Basic Information

Gene Symbol
-
Assembly
GCA_037075245.1
Location
JBAMCH010000007.1:8732527-8734872[-]

Transcription Factor Domain

TF Family
THAP
Domain
THAP domain
PFAM
PF05485
TF Group
Zinc-Coordinating Group
Description
The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 2e-13 3.7e-10 40.6 0.0 1 86 73 142 73 143 0.82
2 7 1.5e-09 2.8e-06 28.1 0.1 1 64 170 227 170 242 0.76
3 7 3.7e-11 6.7e-08 33.3 0.0 1 87 246 317 246 317 0.78
4 7 1.3e-14 2.4e-11 44.4 0.1 1 86 340 414 340 415 0.85
5 7 1.1e-06 0.002 19.0 1.0 1 58 448 494 448 522 0.83
6 7 7.4e-12 1.3e-08 35.6 0.3 1 87 532 602 532 602 0.81
7 7 7.9e-15 1.4e-11 45.1 0.2 1 86 675 747 675 748 0.80

Sequence Information

Coding Sequence
ATGGAGCAAGTTCAGGTGATGGAGGAGCCACAATCAGACGACGAGGACTGTCAATTCGTGGAGGATATGAAAATCAAGGTGGAGGTGGCACCTTCAATGGAAGAGGAACAACAGTCGGACGAGGACTCTCCAATGGAGGAGGAGATATATGTTAAGGAGGAGCCCTGCATGCTGGATAAAGTTAAGGAAGATCCAGATCGCATCCGGACACCCAACTGTTCAATTCCCACCTGCGGACAGCAGGAAACCAGTCAAATTCGACTCTTCCGCTTTCCCAACCAGGAAAATATCTTTATCCAGTGGCTGGTGAACACCGATATGAAGCCTCACCTCGTTAATCCCCTAGAGCTTCTTGTGTGTCAGTTGCACTTCGAACCCCAAGCCATTATGGGCTATGAGCTCCACAGTTGGGCGGTGCCCACATTGCTCCTCGGCCATGCAGGCCATGTGATTCCACTTGCCCAACAGCCGTCTGAGCAAGTGATGCAGGACATCCGAAAGCGGTACTGTTCCGTGCTCAGTTGCTTTCGGGCCAAAGACGAGGGATACCGGCTATATGAATACCCAGAAGACGAGACCACTCGTCGCAAGTGGATACGGCGAAGCAGTCACAACCCAGTGCTGGTCACTAGACACGGGTATCGCCTATGCCAGTCGCACTTTACCCCGAACTGCTTCGATCCGGAGACGGGTGACTTGTTTGCAGGCTCGTTACCAACCAGGGAGCTGTTCACATGCCTAGTGCCTGGCTGTGCGAAGGACTCAGGTGCTTCTGTCGGCTACTACAAAATACCGATAATTAACAGCATACTGGATGGCTGGAGCAACAACCTCTTTATCCCTCATCGGGATCTCTATCGGGATGATCTTCGCGTTTGCAGCCGTCACTTCGAGGACTACTGCTTCACGAATGACAACAGACTTCGGCCTGGCTCGCTGCCCACTCTTTTCCTGGGTCACAGCCAAGCAATCCTGCCAAATCCGCAAAGAATTAGTTCCCAGACTCAAAATATAGCTTGCGCAGTGCCCGGCTGTGGACGCATCCGGAAGCCTGAAGAGAGTCCCTTCTCGCCGTTTCCAAAGCTACCCGCTCTGAGCAGAAAGTGGATACACAACTTTCGACTGGACGCCACCGTGGAGACGGTGAAGGGAATGATTGTGTGCGATGAGCACTTCGAGAAGGCCTGCTTAAAACAAACTTCGGGACCAAATCGAGTGCGTACGGGAGCCATGCCGACCTTGAAACTGGGTCATTCCCATCGCGATATATACTATACCAATACGAATCTTCGGGGAAAAACattaaagcatttttcaaaGACTAAAAAATACAGTTTAGATTGCTGCTATCCCGATTGTGTAGAGCAGCATAAAGTCACTTGCTACGATCTGCCCCGGATGGAAAATCTCCGCAAAGCGTGGCTCAGCCACATGAACATTGAATTGCCATCGGATGATTTGCAGCTATGTCCGCTGCACTTCATCATTCTGTACGAGCACAGTGCCATCAACTTTTCCGATCATGCTCCCGACACATCTCTGGACAATAATTACAAGTGCGCCCGAAGCCAGAAACGAATGCAGTTCCTAAGGTGCGCCATCAAAGGATGCAATACCTTCCAGCCCAGAGATGGAGGCATCCTGCATGGTATGAAGTCCCTTAAGGAAATCGAACAGATGTGGGTGGAAAACGGTCAGATGGAGTTGAAACGTCAAAAAAGCTACAATCGTGTGTGTAGTAAGCATTTTGAACCACAGTGCTTCGAAGGTCAACGAATCCAGGAGTGGAGTGTGCCCACCCTGCACCTGCCGGGCGAGGCAGTGCATCAGAATGTTACCCTGGAGCAGTATAAGCTTTACAGCGAGACGGCAAAACATAATGATTGGGAAGACGAAGAAGATGTTGATTATTCGGATCCCAATCCCCTTGCCGGGGAAACCTTGAGCGAAACCCTAGAACAGACTGAGGATCAATCCCTGGAGCAGATCCCCTCTAACAGGAAACAGTATAGTACCAATCGCTGTGCTGTTCCGGGTTGCCTGAAGACTTTCAAGGACGTTACCAGAACATTCCGGCTGCACAAACTCCCCGATTCCGAGGAAGCAGCCAACATGTGGCTACACAACACCCAGGTGAAGATGGACAGGCAGTACTGGCCCAGCTTTCGCATCTGCAGCCTCCACTTCGATGAGGATTCCTTCCAGGGTTCGAGGGTGAGGAAGGGCGCCATGCCCACGCTTCGCATGGCAAGTTTGCTGCGGGGATCGATGTACGAAAGTGAGTGGACAGCCAAGAaatggaaacccccctccagGTTTCCAAGAGCAGTGAAGAATAGAACGTAA
Protein Sequence
MEQVQVMEEPQSDDEDCQFVEDMKIKVEVAPSMEEEQQSDEDSPMEEEIYVKEEPCMLDKVKEDPDRIRTPNCSIPTCGQQETSQIRLFRFPNQENIFIQWLVNTDMKPHLVNPLELLVCQLHFEPQAIMGYELHSWAVPTLLLGHAGHVIPLAQQPSEQVMQDIRKRYCSVLSCFRAKDEGYRLYEYPEDETTRRKWIRRSSHNPVLVTRHGYRLCQSHFTPNCFDPETGDLFAGSLPTRELFTCLVPGCAKDSGASVGYYKIPIINSILDGWSNNLFIPHRDLYRDDLRVCSRHFEDYCFTNDNRLRPGSLPTLFLGHSQAILPNPQRISSQTQNIACAVPGCGRIRKPEESPFSPFPKLPALSRKWIHNFRLDATVETVKGMIVCDEHFEKACLKQTSGPNRVRTGAMPTLKLGHSHRDIYYTNTNLRGKTLKHFSKTKKYSLDCCYPDCVEQHKVTCYDLPRMENLRKAWLSHMNIELPSDDLQLCPLHFIILYEHSAINFSDHAPDTSLDNNYKCARSQKRMQFLRCAIKGCNTFQPRDGGILHGMKSLKEIEQMWVENGQMELKRQKSYNRVCSKHFEPQCFEGQRIQEWSVPTLHLPGEAVHQNVTLEQYKLYSETAKHNDWEDEEDVDYSDPNPLAGETLSETLEQTEDQSLEQIPSNRKQYSTNRCAVPGCLKTFKDVTRTFRLHKLPDSEEAANMWLHNTQVKMDRQYWPSFRICSLHFDEDSFQGSRVRKGAMPTLRMASLLRGSMYESEWTAKKWKPPSRFPRAVKNRT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-