Basic Information

Gene Symbol
-
Assembly
GCA_004143905.1
Location
SCDX01000489.1:68696-71696[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.098 6.9 7.1 1.4 1 21 239 259 239 260 0.94
2 7 0.0014 0.097 13.0 2.3 1 23 266 289 266 289 0.96
3 7 0.00022 0.016 15.4 1.0 2 23 296 318 296 318 0.97
4 7 0.017 1.2 9.5 3.8 1 23 357 379 357 379 0.99
5 7 0.024 1.7 9.1 0.7 1 23 386 408 386 408 0.97
6 7 0.0062 0.43 10.9 0.2 1 23 413 435 413 435 0.95
7 7 0.00027 0.019 15.2 2.6 1 23 489 511 489 511 0.98

Sequence Information

Coding Sequence
ATGAACAATCAACTAAACCCGGCCACCTACCgcaaattcaataatttgctCAGCAGCGGCGCTGTCACCGTCACCGGTCCCGGCCAGCCGCGCATATTGAAAACAACGCGCCTGGCGACACCTGGAGGCGGGGGCTCAAACGCGAGCGCcgcgtcgcagcagcagcaacagcagcaaaatatCATGGACTCGATGGCGGCCCTGCGGTGTTACATCTGCGATGAGGCGCTGCTCTCCAACCAGACGCAGACCTCGCTGACGGAAATGTGCACATCGCACACGTCCACCAAGTTCCCGAACAAGCTGGCCCAACTGGTGGGCGAGGGCTTCTTGGTGATTGTGTGCAACGAGGATTTCGTGTGCTCGCGCTGCACCAACCTGGTCAACTACTACGACCGCCTGGAGAACGACGTGGAGCGCGTCAAGTCCAACTTGCTGAACTTGCTGAATAAGAAGTACGGCATCAATGAGgacagcggcggcagcaactcGGACGCAGCCAGTCCGCCGCTCAAGATGCAGAAGCTGAGCAGCGGCGCGGGTAATCGTTCGTTGGATGAGGGCAGCGGCGCGGGCGCGACCGGGGATGTGCTACGCACACGCAAGCTGGTGCAGCAGTCAACGCCAGCCTCGCAGCAGCTAAAGCTGGCGACGCCACAGGGCGGCGTCGTAGCGGGCACACAGACGCAGGTTCAGCGCAAGGCGACCAAGATTTACAAGTGCACCTCGTGCGATTACAAGACCTCGGACATGCGTCTTTTTAACACGCACTACGAGACCTGCAAGCAGCAGACGTTCCAGTGCAAGACCTGCCGCAAGATCTTCCCCCACTTTGGCGCCATGAAACAGCACATGGTGCGGGATCACAACACCGCGATGGACAACACCTGCGCCATGTGCCACATCAATTTCGTGAACGAGGCCAGCCTGCGCAAGCACATGGAAACGAATCACGCGACAAACGTGCTGGTCACCAGCACCACAACAATAcccgctgccgctgcgccggtcacagcggctgctgctgccgctgccgccgctgctgccgctggtgtCTCCGAGTCTCTGTACACATGCAACCACTGTCAGTTCAAGTCGACCGACAAGGGCGTCTTCGATGAGCACATGCGCAAGCATGTCAGCAAGCCGAAGCCGTTCAAGTGCCGGCTCTGCTCGCAGCGCTTTGAGACCCGCGAGGCGGCCACCGTGCACGCCAAGCAGCACCAGACGAACTACTTCAAGTGCGGCCAGTGCGCCATGAGTTTCCCCAAGCGCGAGCTGCTCGTCAAGCACGCCGAGCTGCATCAGGCCGAGAAGCTGTCAGCCGCCGGCGGTGGCCAGAACTTGAACACACAGAAGCTGCTCCAGGAGACCATCGACGAGGCGCTCAGCGACAGCGTGCCGGCCCAGGCCGGGGGCACGGTTGTGGCCACCGCAGCCGAGGCGGAGAACAACATACGCTTCTTCTCGTGCAGCATCTGCTCGCTGACATTCATCCAGGAGACGTACTACAATCACCACATGGAGACGCACAGGCGCGACAAGAAGAGCGCAgccgctggcggcggcggtggcaccACAGCCCTCAACTCCGCGGCCACGGCGCTGCTCAGCGACGAGCCGAGCGAGTCGAGCGCCAGCGCCAAGGAGGAGAGCAGCGAGCAGAGCGCCGAGGCGGACATTGAGAGTCTGTTCGAGAAGCTGCACTCGGAGAAGAACGACACCGAGAAGAGCGGCAAGAATGAGATGGTCATCACCTCGCAGGAGGGCAGCGGTGGCATAACATTCAACATAACCATACCACAGGTGGATGCCACTGGCGAGCAGGTCGAGAAGAACTCGCCCAATTCGCAGGCGCCCGTCTCGGTCAGCATTGACATGCCGGTGCTGGACCAGGCCGAAGAGGAGGAGTCGCAATCGCAGAGCAGCAATGACAAGACAACCGAAGCCAGCAGCAAGTCGGGCACCGCGCCCGTCTCCATGCCCAGTCTGGACGACGACAATGAGGCAGCCGCAGCCAACGCAGCGGACACAACAGACGGCAATGCAGCCAGCAGCAAGGCCGGCGAGAAAGCTGGCGCCAAGTCAGACCAGGCGGCGACCAAGGAGAAGGCCAAGGAGGCTGCCGAAGAAGCAGCCGATCCGGAGGGCGAGGCTGAGAAACGTGAAGCCGCAGATACGCCCTCAGCTGAGCAGGCGGCTGAATCGGAGGCTGCAGCCAATGAAGCGGCCGAGGCCGAGGCAGCTGCCACAGCAGAAGGCGAAGCTGCCGAAGCAGCTGGCGGCGAAGCCATGGAACTGGACGAGGCCATGCAGGCTCAGGTCGATGGCGGTCAAATCAAGTTCATCGTCAACGAGAACGggcacctgctgcagctggacaACCATATACTGACCGATGCCGATGGCAACCAGATAATAGTCCAGGATCCGGAGCAAatacagcagctgctgcagagcGTCGGTGTGCTGCAGTCGGGCGAGGGACTCGAGGGCGAGACGCTCCAAATGATGACCGATGGCAGTGGCCAGATGGTGCTCGTCCATGGCGACAACaatgagcagcagctgatcgatGCCTCGCTGCTCAACTCCGAGGGACAAATCATAATACAGCAGGGCCAGGATGGTGAGGAGGGGCCGCATGTCATTAGCGAGGATGGCACACACATACCCGTCTCCGTCTCCTACACCGAAGATGGCCAGCCCATTGTCcaggtgcagcagcaggtacTGGAGGCGGCCCAGGCCGGCGCCGAAGAGAaggaggcagcggcagcggccgcCCAGGAGGAGGCCGCCGAGCAAGCGCAAACCAGTGAAGCCGTCACAGTCACCACAGCCGCTGCTGCGGTGACCACCAGCACGGCCAGCAGTAGCACTGGCGGCACGGCGGGCTTCTTTGCGCTCGAGGAATTCGCAGAGACGAAAACTGACTAG
Protein Sequence
MNNQLNPATYRKFNNLLSSGAVTVTGPGQPRILKTTRLATPGGGGSNASAASQQQQQQQNIMDSMAALRCYICDEALLSNQTQTSLTEMCTSHTSTKFPNKLAQLVGEGFLVIVCNEDFVCSRCTNLVNYYDRLENDVERVKSNLLNLLNKKYGINEDSGGSNSDAASPPLKMQKLSSGAGNRSLDEGSGAGATGDVLRTRKLVQQSTPASQQLKLATPQGGVVAGTQTQVQRKATKIYKCTSCDYKTSDMRLFNTHYETCKQQTFQCKTCRKIFPHFGAMKQHMVRDHNTAMDNTCAMCHINFVNEASLRKHMETNHATNVLVTSTTTIPAAAAPVTAAAAAAAAAAAAGVSESLYTCNHCQFKSTDKGVFDEHMRKHVSKPKPFKCRLCSQRFETREAATVHAKQHQTNYFKCGQCAMSFPKRELLVKHAELHQAEKLSAAGGGQNLNTQKLLQETIDEALSDSVPAQAGGTVVATAAEAENNIRFFSCSICSLTFIQETYYNHHMETHRRDKKSAAAGGGGGTTALNSAATALLSDEPSESSASAKEESSEQSAEADIESLFEKLHSEKNDTEKSGKNEMVITSQEGSGGITFNITIPQVDATGEQVEKNSPNSQAPVSVSIDMPVLDQAEEEESQSQSSNDKTTEASSKSGTAPVSMPSLDDDNEAAAANAADTTDGNAASSKAGEKAGAKSDQAATKEKAKEAAEEAADPEGEAEKREAADTPSAEQAAESEAAANEAAEAEAAATAEGEAAEAAGGEAMELDEAMQAQVDGGQIKFIVNENGHLLQLDNHILTDADGNQIIVQDPEQIQQLLQSVGVLQSGEGLEGETLQMMTDGSGQMVLVHGDNNEQQLIDASLLNSEGQIIIQQGQDGEEGPHVISEDGTHIPVSVSYTEDGQPIVQVQQQVLEAAQAGAEEKEAAAAAAQEEAAEQAQTSEAVTVTTAAAAVTTSTASSSTGGTAGFFALEEFAETKTD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00476960;
90% Identity
iTF_00561344;
80% Identity
-