Basic Information

Insect: Drosophila micromelanica
Gene Symbol: -
Assembly: GCA_004143905.1
Location: SCDX01001273.1:23545-28778[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0008 0.056 13.7 0.5 1 23 143 165 143 165 0.98

2 14 0.00011 0.0075 16.5 1.3 1 23 398 420 398 420 0.98

3 14 4.5 3.1e+02 1.9 0.4 1 23 426 449 426 449 0.90

4 14 0.59 41 4.7 0.2 1 23 472 495 472 495 0.94

5 14 0.00094 0.066 13.5 1.9 3 23 768 788 767 788 0.92

6 14 0.038 2.7 8.4 1.4 1 23 794 817 794 817 0.98

7 14 1 73 3.9 1.8 2 23 854 875 853 876 0.87

8 14 0.0024 0.17 12.2 0.7 1 23 897 920 897 920 0.97

9 14 0.015 1.1 9.7 0.4 1 23 1067 1090 1067 1090 0.90

10 14 0.00057 0.04 14.2 4.8 1 23 1103 1125 1103 1125 0.98

11 14 0.00012 0.0085 16.3 0.1 2 23 1131 1153 1130 1153 0.96

12 14 0.0011 0.074 13.3 2.9 2 23 1160 1184 1159 1184 0.89

13 14 0.5 35 4.9 0.7 1 23 1189 1211 1189 1211 0.93

14 14 0.079 5.5 7.4 1.5 1 23 1217 1240 1217 1240 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0008	0.056	13.7	0.5	1	23	143	165	143	165	0.98
2	14	0.00011	0.0075	16.5	1.3	1	23	398	420	398	420	0.98
3	14	4.5	3.1e+02	1.9	0.4	1	23	426	449	426	449	0.90
4	14	0.59	41	4.7	0.2	1	23	472	495	472	495	0.94
5	14	0.00094	0.066	13.5	1.9	3	23	768	788	767	788	0.92
6	14	0.038	2.7	8.4	1.4	1	23	794	817	794	817	0.98
7	14	1	73	3.9	1.8	2	23	854	875	853	876	0.87
8	14	0.0024	0.17	12.2	0.7	1	23	897	920	897	920	0.97
9	14	0.015	1.1	9.7	0.4	1	23	1067	1090	1067	1090	0.90
10	14	0.00057	0.04	14.2	4.8	1	23	1103	1125	1103	1125	0.98
11	14	0.00012	0.0085	16.3	0.1	2	23	1131	1153	1130	1153	0.96
12	14	0.0011	0.074	13.3	2.9	2	23	1160	1184	1159	1184	0.89
13	14	0.5	35	4.9	0.7	1	23	1189	1211	1189	1211	0.93
14	14	0.079	5.5	7.4	1.5	1	23	1217	1240	1217	1240	0.95

Sequence Information

Coding Sequence: ATGGCGCACAAGCGTATGAAAACAGAGAACAtggcaataaattataaatttgcgTGTCGCTGTTGCCTCAAATCCGAGGCGGAGTTCTTCAAGCTGGACTCGCTAATCGACTGCGGGATCGGCGACAACGATGCGACCGCAACGAAAATACCCCTTATACGTTTACTATTGTTCTGCATGCGCACGGAAAATCTGCCCGAGCTGCCGCAATACATTTGCGCTGAATGCAGCAAGAGTTTGCAAATAGCCTATCTGTTCATACAGAACGGCTTGCGCGCCCACGAGATACTCTGCCGCAAATTGTGCCCCGGCCAGTTGAAGTCCACAACGCGCTCGAATGGCCAACACATGTCTCTGACGCAAGAGCCCGAGGACGCGACGCTGGGCAGGCACGGGGAGCTGAAGTCAACAAAAGCCGCTGTGCGACACGAATGCAAAGTATGCGGTGCCATTATCTACAATCGCATGGAGCTCAAGCAGCACATACGCATGCATACAGAGGCGTCGCGACATCAGTGCAAATTGTGCAATTTTGTCACGCTCAAGCATCGCCAGCTGCCGGAGCATTATCGCAAGGCGCACGGCCTTACGGCTGCCCAAATTGAGCATCAGCTCAAAATACGTAGATCCATGCAGGCGGCAGCAAATGCAATACCAACATCAACAGCGgctgcgacaacaacaacaggagcaacaacaacagctgcggACGATGATCAAGTGAAGGTGTGCACACTGGAGGATATGGAGCTGCTGATACCCACTGTGCTGACGCCGGAGGATTTTTCGCATCCACAATTGGATGCGGAACAGTTGCGTGATATTGAACAACAATTGGCAAACTCGCTGCCCGTCTCACAGTCCAGTTCAGCGTACGCTGCGGAACCAACGATAGCTGCTGGCGGTGGCGCCAATGTGACCATAGGCGCCGAGTTTCTGGTCCTGCCCGATGGCTCGTTGCAGCAGGTGAACGACGGCGGTGTCGTGTTCGAATATATTGACGATAGCAAGAACATCGCCAATGCGGCAACCAATATGACGTTGCAGAGCCTGTTGGGTGATTCCAAGCCAGATTTAACATATGACCCCATGGATATCGATCTGAGTCATATGGTGGTCGACAATGCGCTGCCGCAAATaacagtTAAGCCAAAGCCACGGCCGGCACCAGCGTCAACGGGCGCCTTGAAGCACAAATGCAAACTGTGCCCCAAAGCATTTCCCACAGTGGCACGTCTGAAATCTCATCAATTAACCCATAGTCATTTGCCCAAATTCTATTGCGATCAGTGCGCTTATTATTCGCTGCGCAGCGCCGATCTCATCCAGCATTATACCACGGAGCACAAGTCCTGCGTTACCGAAAGTCGGGCGAACCATTATGATAAGCTGCCCGGGGACAGGAGTCGCATATATTCCTGCGATATGTGCCTGTTTGAGGCGCCGAGCAGTGGTCAGCTGCGTGTACATTACAGCAATAAGCATATGGTTGTGCCCAGTGAGGTGCAGCTGCGTCCCACCTGGACGCACGAGTCGAGGGTGGGGGATGGCAACTCGACGCTAGCTGACGGCAACGGCTCCGCACAGCCAGACATACCGCTGGGCATCAAATATCCGCCAATGATGTCGTCGGGAACAACAACCGAGCCAACAGCGACGCCAACAACTGCCATTAGGCAGCCGGGGCaggctacaacaacaactgtggtAACGCCAGATGGAGAAATTAATGTTGTGGTTGATGCCACATCGTTATTCTATGCAGCGGGTGCAGTGGACCAGTTAGCGACAACAACGGAAGGGAcgacaaggacaacaacaacaacgacggcaTCAGCAACTAGTTCAAACACATTTGGATTGTTTCCAGAGCAATCGTTTGGCAACAGTATGgcgagcacaacaacaatgtcgCAGGAGCCAAACGGTGTGCCGTCTACGACATCCGCATCGAATCCAAATACTAGCATCTTTGGTGATATGCAGGATTTTATTGATAACACCGATGTGGCTGCCATATGCACCATACCCGCCGATGATATGCCCGTGGTCGATGGCGATGACATTGTTAttgataacaataatataagtCTGGACTTTGATGCGGAAAATCTATTTGAAGACTTCGAGGATGTTGAGGTCGGCGAagaggatgatgatgatgacgacgacgatgccGAAAATGAGGATGAGAATGATAACAATAATGCGGCGGCCGATCAAAATCTATTGCTGACCAGCGACGATGACGATGTGGATGACTTTGATGACGAACAGTCGAAGCATCTGCAGAAACCATATTGCATCTATTGTAACAAGAAGTTCACCAGCCAATACAAGTTTGAGAATCACATGTTTGTGCATCGCGgTTTGGCGCCTTATCGCTGTGAACTGTGCACCAATCTGTACAATATGAAACGTCTGCTCATACGGCATTATAAGACGGTGCACAAGCGAATGCCCACACGGGACATGGTGCAGGCGAAGGGCGATAAGGTATCCGTGGCGAGTACAACCATTGAAAAAATACAAGTTAATAATGACAAACCTCCTATGCTAATGTGCGCCAAGTGTCCCTTCGAATGCGAGCTTGAGAGTGAAATGCGCAAGCATCTGAATGCGCATCATGGCATCAACGATGGCGTATCTGTGCATGCTAACGAGGTGTTTATCATACGCAAACTGCCCTATGAGTGTCCACGTTGCATACGCTCATTTGCGGCCAAACGAACGCTGACTCGCCATTTGCAACGTAGCCATTTGGTGGACACAATCATTGAGATGCAGGCGCCTCAATTGACAACTAGCTCAGCGGCCACCACGACCACATCGACGGCAACAACCACATTGCCGCTGAACGCCAGTGAtggcaataaaacaacaacaacagtaacagcaacacaaCTGGATTCCAACATGTTGGCGCCGCAAGACGCCGAGACTGTCgacggcgatggcgatggcgatggaaAATGCGgCTCTACGCTCTTTCCAACGCCCACGCCATTTGACTTTGATCTTGATTTTATTGGGAATGGTGCAcaagctgccacgcccattaagattaacaacaacgacaacttcAACATTGCACCGAATTCCAGTCATCTGCTTAATGGCAGCGATAAGCTGCTGACTGCAGCGTTGGAGCCATCGCCAGTTAAGGATTTGCGCACACGGCTGCCGCGCACACCCATCTTTGTGTGCAAGCAATGCAATCAGACCTTCGATGAGCTCGGCAAGCTGTTGCAGCACGAACTGGATCAACATTCCAGCGGCATTGTGTCGCCGCGCAGCAGTTACCAGCATCAGTGCAAGATCTGTAAGACCACATACCGCACCATAACGCTACTCAACTATCATATGAAACGGCATGCGCCAGTCAAAATTCCGTGTAAGCAGTGCTCCAAGGAGTTTGAGGAGAGTTCGGATTTGGAACAGCATATACAGTCCGAGCATAGCGCCAATATGCCCCTCCAATGCGGCGTGGATGGCTGCACGAAGACATTCGCCTTTAAACATCATTTGAAGCGTCATCAGACGGCCTCCCATACGCCGGTTCAGTATATTTGTCCGGAGTGCGGATGCGATATGCTAACCAGTCTGCAGCTGAGGAATCATTTGTCCACGCACAAGGGTACACATTCCTACAAGTGTCCCAAATGCGTGCGCACTTATTTGCGGCGAAAACCTTTTCGAAGACATGCGCTACGTGAGCACAAATGGGAGCTGACCGAGGaagaaattgataaaatatattgcttGAATAGTCCATCGCCGTCAATCAAATTACGTGAACGAAGATCGGTGAAGGCCGAGAGGGACCGGTATGACTAG
Protein Sequence: MAHKRMKTENMAINYKFACRCCLKSEAEFFKLDSLIDCGIGDNDATATKIPLIRLLLFCMRTENLPELPQYICAECSKSLQIAYLFIQNGLRAHEILCRKLCPGQLKSTTRSNGQHMSLTQEPEDATLGRHGELKSTKAAVRHECKVCGAIIYNRMELKQHIRMHTEASRHQCKLCNFVTLKHRQLPEHYRKAHGLTAAQIEHQLKIRRSMQAAANAIPTSTAAATTTTGATTTAADDDQVKVCTLEDMELLIPTVLTPEDFSHPQLDAEQLRDIEQQLANSLPVSQSSSAYAAEPTIAAGGGANVTIGAEFLVLPDGSLQQVNDGGVVFEYIDDSKNIANAATNMTLQSLLGDSKPDLTYDPMDIDLSHMVVDNALPQITVKPKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCAYYSLRSADLIQHYTTEHKSCVTESRANHYDKLPGDRSRIYSCDMCLFEAPSSGQLRVHYSNKHMVVPSEVQLRPTWTHESRVGDGNSTLADGNGSAQPDIPLGIKYPPMMSSGTTTEPTATPTTAIRQPGQATTTTVVTPDGEINVVVDATSLFYAAGAVDQLATTTEGTTRTTTTTTASATSSNTFGLFPEQSFGNSMASTTTMSQEPNGVPSTTSASNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDDDDDDDDAENEDENDNNNAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVASTTIEKIQVNNDKPPMLMCAKCPFECELESEMRKHLNAHHGINDGVSVHANEVFIIRKLPYECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLNASDGNKTTTTVTATQLDSNMLAPQDAETVDGDGDGDGKCGSTLFPTPTPFDFDLDFIGNGAQAATPIKINNNDNFNIAPNSSHLLNGSDKLLTAALEPSPVKDLRTRLPRTPIFVCKQCNQTFDELGKLLQHELDQHSSGIVSPRSSYQHQCKICKTTYRTITLLNYHMKRHAPVKIPCKQCSKEFEESSDLEQHIQSEHSANMPLQCGVDGCTKTFAFKHHLKRHQTASHTPVQYICPECGCDMLTSLQLRNHLSTHKGTHSYKCPKCVRTYLRRKPFRRHALREHKWELTEEEIDKIYCLNSPSPSIKLRERRSVKAERDRYD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598403;
90% Identity: -
80% Identity: -