Basic Information

Insect: Drosophila micromelanica
Gene Symbol: L
Assembly: GCA_004143905.1
Location: SCDX01001009.1:25093-34569[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 8.8e-06 0.00061 19.9 2.9 1 23 163 185 163 185 0.98

2 17 0.3 21 5.6 6.2 1 23 191 213 191 213 0.97

3 17 1.5e-07 1e-05 25.5 3.2 1 23 219 241 219 241 0.99

4 17 1.1e-05 0.00075 19.6 0.4 1 23 247 269 247 269 0.99

5 17 0.011 0.75 10.2 0.2 2 23 343 367 342 367 0.92

6 17 0.00069 0.049 13.9 0.2 2 23 397 419 396 419 0.95

7 17 0.092 6.4 7.2 0.4 1 23 499 521 499 521 0.95

8 17 0.018 1.3 9.4 0.1 2 23 529 550 528 550 0.91

9 17 0.00056 0.039 14.2 0.1 1 23 558 582 558 582 0.94

10 17 4.3 3e+02 2.0 0.9 2 23 618 640 617 640 0.94

11 17 0.0022 0.15 12.3 1.1 1 23 700 723 700 723 0.97

12 17 0.0023 0.16 12.3 2.3 2 23 897 919 896 919 0.96

13 17 0.099 6.9 7.1 0.1 1 23 925 947 925 947 0.92

14 17 1.2 84 3.7 1.2 2 23 955 976 954 976 0.93

15 17 0.34 24 5.4 1.2 1 23 1075 1097 1075 1097 0.94

16 17 0.026 1.8 8.9 0.0 1 23 1107 1129 1107 1129 0.95

17 17 0.00065 0.046 14.0 2.0 1 23 1134 1156 1134 1156 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	8.8e-06	0.00061	19.9	2.9	1	23	163	185	163	185	0.98
2	17	0.3	21	5.6	6.2	1	23	191	213	191	213	0.97
3	17	1.5e-07	1e-05	25.5	3.2	1	23	219	241	219	241	0.99
4	17	1.1e-05	0.00075	19.6	0.4	1	23	247	269	247	269	0.99
5	17	0.011	0.75	10.2	0.2	2	23	343	367	342	367	0.92
6	17	0.00069	0.049	13.9	0.2	2	23	397	419	396	419	0.95
7	17	0.092	6.4	7.2	0.4	1	23	499	521	499	521	0.95
8	17	0.018	1.3	9.4	0.1	2	23	529	550	528	550	0.91
9	17	0.00056	0.039	14.2	0.1	1	23	558	582	558	582	0.94
10	17	4.3	3e+02	2.0	0.9	2	23	618	640	617	640	0.94
11	17	0.0022	0.15	12.3	1.1	1	23	700	723	700	723	0.97
12	17	0.0023	0.16	12.3	2.3	2	23	897	919	896	919	0.96
13	17	0.099	6.9	7.1	0.1	1	23	925	947	925	947	0.92
14	17	1.2	84	3.7	1.2	2	23	955	976	954	976	0.93
15	17	0.34	24	5.4	1.2	1	23	1075	1097	1075	1097	0.94
16	17	0.026	1.8	8.9	0.0	1	23	1107	1129	1107	1129	0.95
17	17	0.00065	0.046	14.0	2.0	1	23	1134	1156	1134	1156	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGGAGAACTTAATTGAAAAGATTCAAGCCACCAAGGAGATTACAAATAACGACATGTACAGCACGCACACCTCCTCCAGCTACTCGCCGAGCATCTCCGATGGCACTTTGACGCCCAACTCGATGCCGCAGCTGGCGGCGCAGGGCGACGAGTCCGCCACGGAGACGAAGGCGAATGGGGAAACAGTGTCCGGCacggaggagcagcagcagcaggagccaATTAGGCCAAAGCGTCCGGCACAtttgcatcatcatcatcaccatcattatcatcatcagcaggCGCTGAAAATTGCCAACAAGCTGCGCAAAATCAATAAGGATGCGAAACTGTTAACTGGAACAGGATCGGGCGGCACAGGACAGCCCGGACACAATGCAGCGGGAGCCAAGTTTGATAAGTTGACAGGCGAGGGCATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTGTTCAAACACAAACGCTCCCGAGATCGCCATAAGAAGCTCCACACGAACGAGAGGAACTACAAGTGTCCGCATTGCGAGGCGGCTTTCTCCAGAAGCGATCATCTGAAGATCCACATGAAGACGCACGACATCCAGAAACCGTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACGGCCGCCGCCCTCACCTCCCACATGCAGAAGCACAAGAAGAACGCGGCCATTTTGGCCGCCGGCGGCAATCCGAATGCGCTCAACTACAGTCCCAGATCGACGGGATCCGCCTCGATATCGAGCAATGGCAGCCTGCACAAGCGCCGCTATGCGCTCGCCTTGGCCACCGACAGCAGTCCGAGCCGTCTCGAGTATCCCAAGCGGGCGCGTGCCCAGCTGgcggctgccacgcccacaccgacGCCGCTGCTGCGTTGCAGCTACTGTCCCAAGGTGACCGAGTTCACCAGCCTGGAGCAGCTGAACGCCCATCTGCAGAGCGTCCacgagcagcagccgcagcagcaagagCAGATTCCTCCAGCGGAGGGCGATGGATCCGTCGTGGAGCAGGCGACAAACGGCTTCCAGCTGAGCTGCGAATATTGCACGATGAAATTCGTGAATATTGCGGCACTCTTTCAGCACATGCGCGGCACCCATCTGGACCGGCTGGGCAGTCCGAACTCGTATTACGAGCACTTCAATCGGCTGGCCACGGCGGGCACGTTCAGTCCCCGCCTGGCGGCGGAGTTGCCCAAGCAAATCAAaccggatgcggatgcggatgcgaaattggagcaacaacagcaggagcTGCCCACCGATttgagcagcaacaagagGCGTCCCTTAACACCGCAACCGGCATCAGCAGCGATTGCAGCGCCACCTGGCGTCTTTTTGTGCAACCAGTGCAATGCCGGTTTGCCGGACTTTGAGAGCTTCCGCAACCATCTGAAATCGCACATCGTGGAGGGCATGCAGCTGAGCTGCCCGCACTGCGGCCTCAATCTGCCCGAGCAGAGCGAGTACGAGCGCCACGTGGTCGCCCACTTTCTGATCAGCAGCTCCGAGTTCAAttgcagcgccagctgcgGCAAATCGTACGCGAAGGcggaggagctgcagcagcatctgctGAGCGAGCAtgtccagcagctgctgaagTGCGTCCTCTGCTCGGAGCTGTGCGAGAATCGGATGTCGATGCAGCTGCACCTGGCCTGCGCCCACAGCCAGGAGACGAagctgctgcgctgcagcgCCTGCCTGGAGCTGTTTCGCAGCGATGCCGAGTTCCATGTGCACGTCAAGACGCGCCACCAGCTGGgcggacaacagcagcaacgagagcgggagcgggagcgggaacgggagcgggagcgggagcagcTGAGTGGCGGCGGCCCATCCTCGAATCCGTTGCAGTGCATGTTCTGTCGCGTCGTTTGCGCCTCCGAGCTGGAGATGCACTTCCATTTGGCGGCGCATGCGCGACAATTTCGCTGTCCCAGCTGCCCGGAGACATTCCACGTGGAGTTCCTGCTCGATCGGCACATGCAGAGCCAGCacggcggcgtcggcggcggcgccgccTCCAACAAGGGAGCCAAGGAGCCGGGCGCCAGCATGGGCAGCCTCTATGTGAatgcgctgctgccgccgctggcagcggccgctgctgctgccgccgcggcgaccaacaacaacagcagcctgCACATCGACTACAACGTGGCGTTCAAGGGTCTGTTCGGTGGCggcacggccacgcccacaggcCAACAGGCGAAGTTCTACAGTCCGCTGCAGGTGGACACCAAAGCGGCGCAGCAGACGCCGCATCCGGCGCTGATGTACGGCCTGGGCCAGCGCTACTTGATGGAAATGTACGCGGCCAAGGCGAATTCGCCGGCGACAAGCGCAGCGGAGTTGCCACCGCCAGCGCCACCAATTGTGGCAGCAACCaccggcggcaacaacaatgctaaTTACAGCTGTGGAATGTGCGAGCGTCAGGATTTGCGCAGCGAGGCGGAGCTGCACTCGCATCGGAAGCTGGCGCACAATCTGAAGACGGGCGTCAGCCTGAGGTGCGCCTACTGCTCCGGCAATTACAAGTCGCGCTCGGAGCTGGAGCAGCACATGAAGAGCTGCCACAATTCGAGCGGCAAGCACAAGTGTCTCATTTGCGATGAGATCTTTCCGTCGCCGGCGATTCTCGCCGAGCACAAGCTGCAGCACTCCAAAGTGGGACAGTCGGGCAAGTGCGCCCATTGCGGCCACCAGCTGGAGCATGTGGCCGCCTTCCGGGCGCACCTCGGCGAGCACGGCAACGATGGCAATCTGCCGATGGCCTGCATCTGTTGCCGGCAAACGCTGCACTCGGAATTCGAGCTCAGTCTGCACGCCAAATTCCACACGAAATCGTCGCCGGGCTGCGGCAGCCTCCAGGAACCGGTCTGTGCCCTGTGCCTGGAGCCGCTCCCCGGCGCCGGCGAAACCGCCAAGCTGTGCGACAAATGCTGCCGCAAGCACAATCTGAATGGCAAGCGACCCAAGGAGCCGGCCACCCTGGTGGCGGCACCAGCCACAAAGGCAGCAGGCACAGCCGCGTATCTGGAGCACCGTTGCAATCTCTGCAAGCTGATACTGCCGCACGCCCAGAAGCTGCAGGAGCACCTGGTGGAGCACACATTCGCGGGTACCGAGCAGCGCGGCTTCAATTGCTACATCTGCTCGGCGGTGTTCACGGCGCCCGCCGGACTCCTCAGCCACATGGGGGAGCACGGGGCACGGCCCTACGATTGCAATCTGTGCACCGAGAAGTTCTACTTCCGGGCCGAGCTGGAGCACCATCAGCGGGCGCACGAGCTGCGACCACAGCCAACCACCAAGCAGGAGACCGAGATCAGCTCCGCGGCCAGTTCGCCGATGACGCCGACGACGAGTCCACTGCACGCGGTCAAGCAGGAGCTCTACGAATCGGAGCCGGGCACATCGCCCAGCGGTGAGCAGCCGGCTGTCGGTGACGAGGAGGAGTACATCGAGGTGGAGCAAGTGCCGCAGGAGACACAACGCACTGGAGAGCTGCTCAGCACcgaacgcagcagcagcagcgcctaA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSMPQLAAQGDESATETKANGETVSGTEEQQQQEPIRPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLLTGTGSGGTGQPGHNAAGAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALATDSSPSRLEYPKRARAQLAAATPTPTPLLRCSYCPKVTEFTSLEQLNAHLQSVHEQQPQQQEQIPPAEGDGSVVEQATNGFQLSCEYCTMKFVNIAALFQHMRGTHLDRLGSPNSYYEHFNRLATAGTFSPRLAAELPKQIKPDADADAKLEQQQQELPTDLSSNKRRPLTPQPASAAIAAPPGVFLCNQCNAGLPDFESFRNHLKSHIVEGMQLSCPHCGLNLPEQSEYERHVVAHFLISSSEFNCSASCGKSYAKAEELQQHLLSEHVQQLLKCVLCSELCENRMSMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGQQQQREREREREREREREQLSGGGPSSNPLQCMFCRVVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVGGGAASNKGAKEPGASMGSLYVNALLPPLAAAAAAAAAATNNNSSLHIDYNVAFKGLFGGGTATPTGQQAKFYSPLQVDTKAAQQTPHPALMYGLGQRYLMEMYAAKANSPATSAAELPPPAPPIVAATTGGNNNANYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRSELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGHQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSSPGCGSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRPKEPATLVAAPATKAAGTAAYLEHRCNLCKLILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLSHMGEHGARPYDCNLCTEKFYFRAELEHHQRAHELRPQPTTKQETEISSAASSPMTPTTSPLHAVKQELYESEPGTSPSGEQPAVGDEEEYIEVEQVPQETQRTGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00541932;
80% Identity: -