Basic Information

Insect: Drosophila micromelanica
Gene Symbol: prg
Assembly: GCA_004143905.1
Location: SCDX01000004.1:161782-163614[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.39 27 5.3 0.8 1 21 230 250 230 253 0.81

2 9 0.0012 0.084 13.2 0.1 1 23 259 282 259 282 0.96

3 9 2.1e-06 0.00015 21.9 1.4 1 23 288 310 288 310 0.98

4 9 8.9e-08 6.3e-06 26.2 4.3 1 23 316 338 316 338 0.98

5 9 1.5e-05 0.001 19.2 0.7 1 23 344 366 344 366 0.98

6 9 4.2e-05 0.0029 17.8 0.2 1 23 372 394 372 394 0.99

7 9 2.7e-05 0.0019 18.4 0.5 1 23 456 478 456 478 0.96

8 9 4.5e-05 0.0031 17.7 0.4 1 23 483 506 483 506 0.91

9 9 0.011 0.77 10.1 1.0 1 23 510 532 510 532 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.39	27	5.3	0.8	1	21	230	250	230	253	0.81
2	9	0.0012	0.084	13.2	0.1	1	23	259	282	259	282	0.96
3	9	2.1e-06	0.00015	21.9	1.4	1	23	288	310	288	310	0.98
4	9	8.9e-08	6.3e-06	26.2	4.3	1	23	316	338	316	338	0.98
5	9	1.5e-05	0.001	19.2	0.7	1	23	344	366	344	366	0.98
6	9	4.2e-05	0.0029	17.8	0.2	1	23	372	394	372	394	0.99
7	9	2.7e-05	0.0019	18.4	0.5	1	23	456	478	456	478	0.96
8	9	4.5e-05	0.0031	17.7	0.4	1	23	483	506	483	506	0.91
9	9	0.011	0.77	10.1	1.0	1	23	510	532	510	532	0.98

Sequence Information

Coding Sequence: ATGTTAAATTTAGGGACGGACAACGCAGGAGCTAACAGTGAGGACATGCAAAATCATCGAACATCTACAACGGAGCCAATGCCGTGTCGCCTTTGCCACTCCCGGTTTAAGCTGGACACAGAATCGCCAAACATTTATGAAGCCTGCGTGGATTTTGTTAAAGGAGATTGCGAGACTTCGAACGGCGAGGGCGAAAAGTGCCTAATTGTCGATGTGTGCCAGAGTGTCTGGGGCGTCAAGTACGAGCGCCACGAGTTCCTGCCGGAGCGCATCTGCGTGCGCTGCCTCGAAATGCTGAAGGACTTCTACGAGCAGCGGCGGTGCATGCAGCAACGGGAGTTTGAGCTGCAACAGGATTTGAAAGGCATTATTTCTCTGGACGCTAAGTACCGGCCTGGCTTGAATGGCAATCCCGGCGTGTTTGAGTTCGAGGAAGGCGAAGAGGGCTGCGTCATTGTCGACGTGGATCCGGATCAGCTGTGCGAGACGAGCGACGATGAGTTCCTAGGTTCCGATGGCGAGGCCGAGCTCGATGACGACGAGTGGGaagacgaggacgaggaggaggCTCAAAACGACGAAGATGTTGACATGCCGCTCGGCATGGATGCCGCTCAAATGGCGCTAATGCAGGCGCATCAAACGGCGGATGCCAGCACCATCGCTAATGCGCATCCGAAAAGCGCATTCCTCTGCCAATACTGCGACCTGGCCTTCACCCTGCAGCAGGACTGCCAGCAGCATGAGCTGGGCGCCCACGACGTCTCTGCCCCCTACAGCTGCAACTATTGCCAGCTGCGCTTGGCCACACGACCCGCTCTCATTGCGCACATCAAGGAGCTGCACGACGCCGAGCGGCCGTATGTGTGCGCCCACTGCAGCAAGGGATTCGTGCGACGCTCGGACCTGAAGAAGCACACGATCGTGCACACTGGTGTGCGGCCCTTCTCGTGCCACGTCTGCTCCAAGAGCTTCTCGCGCAACACGAATCTCACGAAGCATTTGCGCATTCACAGCAGTGTGAAACCGTTTGTGTGCCAGCAGTGCCCGCGGTCTTTTCAGACGCCGCTGGAGCTGATGAAGCACACGCGCTCCCATGCCGAGGTCAAGCCCTACCAGTGCGGACGGTGTCCGGCTTCGTTTGCGCGCAGGGACAAGCTCCTGATGCACCAGCAGGTGCACCTCAAACGCGATgcagaacagcagcaacaaaatgcgcGCGCCAACTTGATTGTGCCGCcggagcaactgcagcttcCACTGCATCCCTACGTGGATGCCGATGCTTCAGTGCAGCAGCTACCCTATCAACAGCAACCGGCATCGCAGCCCAAAGCAAAGCAATCGTCGAAGCTGACGCGCAATTTTCGGTGCGACGTCTGTGACAGGGGATTCCAGCGTGAGCGGGATTTGCAGCGCCATCGGGCTCTGCACATGGATAGACTGTTCGCATGCAAGCTGTGCGGACAAGGCTTTAACCGGCCCGAGCAACTGCATCGCCACGAGCTGGAGGCCCATGGCCCCAGCTACACCTGTGCGATATGCTGCATCACCTTTCTGCAGCAGAGCGACCTGGAAACCCACCTCAAAGTTCATGAGCTGCAACACAGTGTGGCCAAGAGCACACAAGAGGCGTCGctagcagctgctgcagcaccgCTGGGACATGCCGAGCAGATGGGAGCTGCTGTGCCGCCCGCCGTGCCGGAGCCTGTCCACGTGCCCAACATGAGACCTTCGGCCGCCGAGTTGTCTTTCTACAGCAATATGATACCCACCATGAATCTGGGCTTTTACAGCGAAACCCGACCCGAAGAGCGCAACGGAATTtga
Protein Sequence: MLNLGTDNAGANSEDMQNHRTSTTEPMPCRLCHSRFKLDTESPNIYEACVDFVKGDCETSNGEGEKCLIVDVCQSVWGVKYERHEFLPERICVRCLEMLKDFYEQRRCMQQREFELQQDLKGIISLDAKYRPGLNGNPGVFEFEEGEEGCVIVDVDPDQLCETSDDEFLGSDGEAELDDDEWEDEDEEEAQNDEDVDMPLGMDAAQMALMQAHQTADASTIANAHPKSAFLCQYCDLAFTLQQDCQQHELGAHDVSAPYSCNYCQLRLATRPALIAHIKELHDAERPYVCAHCSKGFVRRSDLKKHTIVHTGVRPFSCHVCSKSFSRNTNLTKHLRIHSSVKPFVCQQCPRSFQTPLELMKHTRSHAEVKPYQCGRCPASFARRDKLLMHQQVHLKRDAEQQQQNARANLIVPPEQLQLPLHPYVDADASVQQLPYQQQPASQPKAKQSSKLTRNFRCDVCDRGFQRERDLQRHRALHMDRLFACKLCGQGFNRPEQLHRHELEAHGPSYTCAICCITFLQQSDLETHLKVHELQHSVAKSTQEASLAAAAAPLGHAEQMGAAVPPAVPEPVHVPNMRPSAAELSFYSNMIPTMNLGFYSETRPEERNGI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502679;
90% Identity: iTF_00588987;
80% Identity: -