Basic Information

Insect: Drosophila micromelanica
Gene Symbol: -
Assembly: GCA_004143905.1
Location: SCDX01000309.1:46826-50834[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.2 83 3.7 8.5 2 23 331 353 330 353 0.95

2 17 7.2 5e+02 1.3 0.0 1 23 360 385 360 385 0.89

3 17 0.015 1.1 9.7 1.8 2 23 396 417 396 417 0.93

4 17 4.8 3.3e+02 1.8 3.0 2 17 428 443 427 454 0.75

5 17 0.0035 0.24 11.7 0.6 3 23 487 507 485 507 0.95

6 17 0.0013 0.091 13.1 0.7 1 23 515 538 515 538 0.98

7 17 2.5e-05 0.0018 18.4 0.4 2 23 543 564 542 564 0.97

8 17 0.00048 0.034 14.4 0.3 1 23 612 636 612 636 0.91

9 17 0.19 13 6.2 0.6 3 21 643 661 641 662 0.90

10 17 0.0035 0.24 11.7 0.5 1 23 681 706 681 706 0.97

11 17 0.0097 0.68 10.3 1.4 2 23 722 744 721 744 0.93

12 17 0.0008 0.056 13.7 0.4 2 23 750 772 749 772 0.92

13 17 0.00057 0.04 14.2 0.1 2 23 776 798 775 798 0.96

14 17 1.5e-05 0.001 19.2 2.1 1 23 804 826 804 826 0.98

15 17 0.0082 0.58 10.5 1.3 1 23 830 853 830 853 0.93

16 17 5.5e-05 0.0038 17.4 1.6 1 23 859 882 859 882 0.97

17 17 0.00015 0.011 16.0 1.6 1 23 886 914 886 914 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.2	83	3.7	8.5	2	23	331	353	330	353	0.95
2	17	7.2	5e+02	1.3	0.0	1	23	360	385	360	385	0.89
3	17	0.015	1.1	9.7	1.8	2	23	396	417	396	417	0.93
4	17	4.8	3.3e+02	1.8	3.0	2	17	428	443	427	454	0.75
5	17	0.0035	0.24	11.7	0.6	3	23	487	507	485	507	0.95
6	17	0.0013	0.091	13.1	0.7	1	23	515	538	515	538	0.98
7	17	2.5e-05	0.0018	18.4	0.4	2	23	543	564	542	564	0.97
8	17	0.00048	0.034	14.4	0.3	1	23	612	636	612	636	0.91
9	17	0.19	13	6.2	0.6	3	21	643	661	641	662	0.90
10	17	0.0035	0.24	11.7	0.5	1	23	681	706	681	706	0.97
11	17	0.0097	0.68	10.3	1.4	2	23	722	744	721	744	0.93
12	17	0.0008	0.056	13.7	0.4	2	23	750	772	749	772	0.92
13	17	0.00057	0.04	14.2	0.1	2	23	776	798	775	798	0.96
14	17	1.5e-05	0.001	19.2	2.1	1	23	804	826	804	826	0.98
15	17	0.0082	0.58	10.5	1.3	1	23	830	853	830	853	0.93
16	17	5.5e-05	0.0038	17.4	1.6	1	23	859	882	859	882	0.97
17	17	0.00015	0.011	16.0	1.6	1	23	886	914	886	914	0.96

Sequence Information

Coding Sequence: atgtcGGAAAATTCAAAAGCCAACCACATTGAGAATGGGCCTAGCTGCCTGCATTGCAGAGTGTACAATTCAAAACACCAATATCAGGAAATATTTGATGAAGTAGGCATCGAAATTGAACTCGCCGATCTGCTGGCCAAATATTTCCAAATTGTCGTCAAGCCCGATGCCCAAAAATCGCAGCTGCTGTGCCAGGAATGTGTGAACACGCTAATACGTTTCTTCGATATAGACGAGCTGCAACGCGAACAAGATGCCGCAAATGCTGCAAAAAAGAAGAGCATCAACGAGCCGGAGACTGTTGAAGAGCCGCCGGCGCCTGCAGTTATAGCCAAAAAAGATGCCAAGCCTGCCAAAAAGCAGGCGGCTTCGCCGCCaaaagcgacaacagcagcgccaaaGAAGTTGGCAGCTCCTGTTAAACCGGAGAAATCAAAGCCGActgcagttgccgctgcacCCGAAGCCGTCGCCGTACGCATAACCAGAGCGAGAACCGCGGCGCCAAAACGTTTGCCCATTAAAGTGAAGCAAGTGATCAAAGCGAGTGGAACGTCCAGTGCGCCCATTGAACAGGAGCAGATAAGCGAGCTAATTCGTGACATCCTAGACGATGAGGAGGCGCCATCCGATGATAAGTTTGCCGAGGCAGCGGCCACAGTGCGCCAGCTGGAGAAGCAAACGGCAGCTGAGGAGGCTGCCGAAAGGCAGGAGGAAGAACAGGAAGAAAACAATGATGAGCTTGAATTTTTGCTGGAACAGGACGATGGCTCCTCGGATTCGGATGTGCGTCATTTCAAAGTGGAGCGTAAAGTCAAATCGACCACATCGCGGTCACAAAATGAAAGCCAAAGCGAGGATGAATCATTCAAAGTGGAGCCTTTCAATTTTGTGCTGATTAAAGAATCTGATAATATTGATGATCTGTACGAGTATTTGGCGACTGTGGTGAAGACTTGCTTTGAAACTTTGCAATTCGATTGGGCCGTTGTTTGCCATCATTGCTCGCTAAAGTGTACCAAATATGAGCACTTCCTTAATCACATAATAAAGCGCCATCAACTGCCGGATGATCACTACAAGTGCCCCATTGAGGGCTGCACTGCTGAGCTGCAGGGACGCAAATCTTTGGCTATGCATTTGGTGGTGCTGCATGCGCCCGTGGCTGAAATACCCATTTATGGCTCTTGTCCCGAGTGCAATATGACCTTCTCCAACATATTGCAGTACAACAAGCATTCCTGCGCCCATGTCATCAAGAAACGTCGCGGCATTCGCTTGTATTGTGAAATGTGCGGCCTGGAGTTTCCCTCCTGGAAGCGCTTTAATTTCCACAATCAATTTCATTTGGAGCGGCATAGGCCGCGCGCCTGTTTTGTGTGCAGCTATGCGGACACCAACATCGATGAGCTGTTCCATCATCTGCACTACGCACACGAACCCGAGGGCACGCTCTTCTGTGATCTCTGTGATCGCACTTTTCGTGATCAGGCCGTCTTTATGGAGCACAATAAGTCGCACGCCAATGTTAGCAGCACAACCTACAGCTGTACCGAGTGCAGCTCGAACTTTGAGACACGCGGTCGTCTCAATAGTCATCTGCGCTCTGCTCATGGCAGCGTCATCAGCTGCGAGCTGTGCAACCGCGAGTTTGCCACAGAGTCCACATACAACATACACATGAAGACCCATTTGATCATTGAGCGCGAGGTGCACGTGTGCAACAGTTGCGGGCTGCTCAGCGAGAGCAATGAGAAGATGGTGGCTCATGTCGAGAATGAGGATTCGGCCTGCTTTGGCATGGACATCAATGTGGAACTGCTGCGTGATGCGTATGTCTGCGAATATTGCTCGGCGTACTTTAAGCAGAAAATCGATTTGCGCGCCCATCGTGATACGGGCGTGCACAAAGATGGTTTCTTCTTGTGTCAGCCTTGTGGGAAGGAGTTTGGCGACATGAAACTCTATCGTCATCATTTGCGCAACTTTCAGCAACAGCGCACGGATATGGCCCATCGCAAGCTAGAGATATGCTTGTACTACATGTGTGATTATGAGGATTGCACTGAGGCTTACATTAACTGGAATTCGCTGTACACACATAAGCGCCGTTCGCACGATGGCCAGGAGAAGCACGAGCCCAAGATTAAAGATAACGAATGGATCTGCCAGTTCTGTCAGAAGGTGTGTCGCTCCAAAATGTCGCTCTCGGTGCATGTAGCGCGCAGTCACAATAACAATAATGTGGTTTGCCCGCTTTGCAAGGCCTCCTATAAGGATAATGATTCGCTCAAAAGCCATCACGCCTATTGGCATGAACCCATTGAATGTCCGATTTGCCTTAAGGTGGTTAAGAATCGAAGAAATTTTGATACCCACATGAATGTGGTGCACTCGAACAATAAGCGTTATTCATGCAGTGTCTGCCAAAAAGGCTTCTATCACAAAAGCGAAATGGAGGCGCATCAGCGGCTGCATACTCAATCCTTTAGCTGCGATAAGTGCAGCTTTACCACTCGGAACAAGAAATCGCTGTCCGTGCACGTGCTGGGACAGCACTACAAACGCTTCGCATTCGAATGCAAGAGCTGCAACAAGCGCTTTGGACGTCGCCAGGGATTATCGAATCATATGCAGCGAGTGCACGGCTCCAGATATACCTGTCACGATTTCTTTGACGGCGGCTGCAACAAAACCTTTGGCTCAACGGCCCAGCTCAATAGGCATGTGCGTAAATCGCACAATGCTAGCATTTTACTCGAAGATGATCTGGCCAAGACGGAGGAAGTTGACGAACTGCTCGACGAGGACTCAACCAGCGATGGACCGTCGACATCGAAAAAACGCTGCATACGCATCAACGACAGTACACAGATTGAGTTCATTGGCGACGCCGCTGTAGCCGAGGATAACGAGAGCCTGGCCGATTCCGATATCTTTGAGGAATTTCAGGAAATCAAAGGCGCCGTAGAGGcgccaccaaaaaaaaaagcaacgtCAAAGTTAGAATAG
Protein Sequence: MSENSKANHIENGPSCLHCRVYNSKHQYQEIFDEVGIEIELADLLAKYFQIVVKPDAQKSQLLCQECVNTLIRFFDIDELQREQDAANAAKKKSINEPETVEEPPAPAVIAKKDAKPAKKQAASPPKATTAAPKKLAAPVKPEKSKPTAVAAAPEAVAVRITRARTAAPKRLPIKVKQVIKASGTSSAPIEQEQISELIRDILDDEEAPSDDKFAEAAATVRQLEKQTAAEEAAERQEEEQEENNDELEFLLEQDDGSSDSDVRHFKVERKVKSTTSRSQNESQSEDESFKVEPFNFVLIKESDNIDDLYEYLATVVKTCFETLQFDWAVVCHHCSLKCTKYEHFLNHIIKRHQLPDDHYKCPIEGCTAELQGRKSLAMHLVVLHAPVAEIPIYGSCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCSYADTNIDELFHHLHYAHEPEGTLFCDLCDRTFRDQAVFMEHNKSHANVSSTTYSCTECSSNFETRGRLNSHLRSAHGSVISCELCNREFATESTYNIHMKTHLIIEREVHVCNSCGLLSESNEKMVAHVENEDSACFGMDINVELLRDAYVCEYCSAYFKQKIDLRAHRDTGVHKDGFFLCQPCGKEFGDMKLYRHHLRNFQQQRTDMAHRKLEICLYYMCDYEDCTEAYINWNSLYTHKRRSHDGQEKHEPKIKDNEWICQFCQKVCRSKMSLSVHVARSHNNNNVVCPLCKASYKDNDSLKSHHAYWHEPIECPICLKVVKNRRNFDTHMNVVHSNNKRYSCSVCQKGFYHKSEMEAHQRLHTQSFSCDKCSFTTRNKKSLSVHVLGQHYKRFAFECKSCNKRFGRRQGLSNHMQRVHGSRYTCHDFFDGGCNKTFGSTAQLNRHVRKSHNASILLEDDLAKTEEVDELLDEDSTSDGPSTSKKRCIRINDSTQIEFIGDAAVAEDNESLADSDIFEEFQEIKGAVEAPPKKKATSKLE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589011;
90% Identity: iTF_00541898;
80% Identity: -