Dmic009470.1
Basic Information
- Insect
- Drosophila micromelanica
- Gene Symbol
- Znf639
- Assembly
- GCA_004143905.1
- Location
- SCDX01001066.1:23449-25523[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0044 0.31 11.4 0.3 3 23 289 310 288 310 0.91 2 10 0.00013 0.0089 16.2 0.5 6 23 319 336 319 336 0.99 3 10 7.6e-06 0.00053 20.1 0.3 1 23 342 365 342 365 0.98 4 10 0.0001 0.0073 16.5 0.5 1 23 377 399 377 399 0.98 5 10 0.00025 0.018 15.3 7.7 1 23 406 429 406 429 0.96 6 10 1.1e-05 0.00074 19.6 1.8 1 23 435 457 435 457 0.96 7 10 0.046 3.2 8.2 0.5 2 23 466 487 465 487 0.96 8 10 3.5e-05 0.0024 18.0 2.4 2 23 493 515 492 515 0.95 9 10 1.6e-07 1.1e-05 25.4 0.7 2 23 522 543 521 543 0.97 10 10 0.00016 0.011 15.9 4.4 1 23 549 572 549 572 0.96
Sequence Information
- Coding Sequence
- ATGATCTGTCGCTtgtgtttaaaaaacataaacgcAAACAATGCCGTCTACCTGTTCGAAACAAACGACACACTGGCCGAATCCTCGCTGCTCAAGATGATAGCCAAGTTTCTCCAGCTCGAGATAATGCCCGATGACAATATCTCGACGAACATTTGCCACGAGTGCTGCGAGCACCTGGAGGACTTTAACAATTTCTGGCAGCTGGTGGAACAGAAGCAGGGAACACTTAAAAAGGAGTTCCTCAACGTGGACGTCGACTGCGTCGCCCTCAAATGGACGGGCGGCATCGATGTGGATGTCAACATTGATGAGCTGCCGCTGGTTGCCGTCGAGATGGACGAGAAGCCGCTGGACATACACAATCTGAGCCTGCTCGGCAGCGTTCTCGACGTGAATGTGGACAGTGTGGAGGTGCCGCAGCTCTCGTCTGTCCCAAAGCCGTCGCGGGATGACGCGTGCCTGCCCCTGGGCACCGTCGACGAGGATGACAACAGGGCCGAGCATGATAACGatatcgacatcgacatcgacgaGAAGCCTCTATTGAATGCCAGCAGCGAAAGCGCTTCCtcagatgatgatgatgatgATGAAGTGCCTCTGGTTAGGCTGCAGCACAAGTTGAAGCCGCAGCGCAAATCACGAACTGGGACGCGCCGCAAGAAGCGCACGCTGACGCTGGCCCAGGAGCTGGACCAGCTGCTGGAGGACAATGAGCACGAGGGCGGCAGGGGGCGTCGCAAGAAGAATGCGACAACCACCGGGCAGAGGAGCGATCTGGAGCGCAAGCCGAAGGGCTGCTCGCGGGCGCAGCTGACCAAGCGGTACGAGGAGGCGATCGCCAGCTACATGGACGCCGACTGTGATCTGTGCGACTACAGCACCAAGTACCTGTCCCAGCTGAAGGTCCACTTCCTGGAGGTGCACCAGCGCGACGCGTATCTCAAGTGCTGCAACAAGGTGTTCAATCGCGCCTCCAAGCTGATGGATCACATACGCAAGCACATCAATCCCAAGCTCTTCACCTGCTCCATTTGCAACAAGTCGCTGAACTCACAGGACTACCTGGCCACGCACATTGAGACGGTGCACAACAAGGTGGCCAAGATCGGCAAAGTGCTCAAGTATCCCTGTCCGAAGTGCGAGCGGACCTTCAGCAGCGAACGGCGACTGGGCAACCATCTGCTCAAGCACGACACGGACCAGTTGGAGCACAGTTGTCACATCTGCCACAAGAGCTTTGCCAATGTGCATAGACTGCGACGGCATATACAGTCGATACACGAGGACCTGCATCCGCATGTCTGCGACATTTGCGGCAAGAAGTTCAAGTTTAAGCCCTCCTTCGAGCGGCACCTGCTGGAGCACCAGGGCGTTGTCGCCCCGGCGATGGAGTGCCCCATCTGCGGTGTCTGGCTGAAGAACGAGCACAGTTTGCGGCTGCATCGATTCACCCACGACAGCACCGACACCGTCTGTCCACACTGCTCGAAGACGTGCAGTTCCCGCACGGCGCTGCGCGCCCACATTCAGTACGCCCACAAGCTGACCACGAGTCTGCAGTGCACCTACTGCGAGAAGAGCTTCAAGCAGCAGCGCAATCTCGAGGAGCACATGGCCATACACACCGGCCTCCAGCTGTACAATTGCCCGCACTGTCCCAAGGAGTGCCGCAGCCGCTCCAACATGTACGTGCACATCAAGCAGCGGCATGCCGACGAGTGGCTCAAGGCCAAAATGGCCCGCTCCAACAATCCGCAATTTAAGCCGCCGGCCTGA
- Protein Sequence
- MICRLCLKNINANNAVYLFETNDTLAESSLLKMIAKFLQLEIMPDDNISTNICHECCEHLEDFNNFWQLVEQKQGTLKKEFLNVDVDCVALKWTGGIDVDVNIDELPLVAVEMDEKPLDIHNLSLLGSVLDVNVDSVEVPQLSSVPKPSRDDACLPLGTVDEDDNRAEHDNDIDIDIDEKPLLNASSESASSDDDDDDEVPLVRLQHKLKPQRKSRTGTRRKKRTLTLAQELDQLLEDNEHEGGRGRRKKNATTTGQRSDLERKPKGCSRAQLTKRYEEAIASYMDADCDLCDYSTKYLSQLKVHFLEVHQRDAYLKCCNKVFNRASKLMDHIRKHINPKLFTCSICNKSLNSQDYLATHIETVHNKVAKIGKVLKYPCPKCERTFSSERRLGNHLLKHDTDQLEHSCHICHKSFANVHRLRRHIQSIHEDLHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECPICGVWLKNEHSLRLHRFTHDSTDTVCPHCSKTCSSRTALRAHIQYAHKLTTSLQCTYCEKSFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSNNPQFKPPA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00610817;
- 90% Identity
- iTF_00561182;
- 80% Identity
- -