Basic Information

Insect: Drosophila mettleri
Gene Symbol: L
Assembly: GCA_035047625.1
Location: JAWNPI010000085.1:3197267-3207835[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.9e-06 0.00067 19.9 2.9 1 23 167 189 167 189 0.98

2 17 0.34 23 5.7 6.2 1 23 195 217 195 217 0.97

3 17 1.6e-07 1.1e-05 25.5 3.2 1 23 223 245 223 245 0.99

4 17 1.2e-05 0.00082 19.7 0.4 1 23 251 273 251 273 0.99

5 17 0.013 0.91 10.1 0.2 2 23 354 378 353 378 0.93

6 17 0.0003 0.02 15.3 0.2 2 23 401 423 400 423 0.96

7 17 0.06 4.1 8.0 0.7 1 23 500 522 500 522 0.97

8 17 0.071 4.8 7.8 0.3 2 23 530 551 529 551 0.91

9 17 0.02 1.4 9.5 1.2 3 23 562 584 559 584 0.86

10 17 3.3 2.2e+02 2.6 1.0 2 23 620 642 619 642 0.95

11 17 0.0025 0.17 12.4 1.1 1 23 685 708 685 708 0.97

12 17 0.0063 0.43 11.1 1.6 2 23 856 878 855 878 0.96

13 17 0.11 7.6 7.2 0.1 1 23 884 906 884 906 0.92

14 17 1.3 92 3.8 1.2 2 23 914 935 913 935 0.93

15 17 0.3 21 5.8 1.3 1 23 1034 1056 1034 1056 0.94

16 17 0.018 1.2 9.7 0.0 1 23 1066 1088 1066 1088 0.96

17 17 0.00021 0.015 15.7 1.2 1 23 1093 1115 1093 1115 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.9e-06	0.00067	19.9	2.9	1	23	167	189	167	189	0.98
2	17	0.34	23	5.7	6.2	1	23	195	217	195	217	0.97
3	17	1.6e-07	1.1e-05	25.5	3.2	1	23	223	245	223	245	0.99
4	17	1.2e-05	0.00082	19.7	0.4	1	23	251	273	251	273	0.99
5	17	0.013	0.91	10.1	0.2	2	23	354	378	353	378	0.93
6	17	0.0003	0.02	15.3	0.2	2	23	401	423	400	423	0.96
7	17	0.06	4.1	8.0	0.7	1	23	500	522	500	522	0.97
8	17	0.071	4.8	7.8	0.3	2	23	530	551	529	551	0.91
9	17	0.02	1.4	9.5	1.2	3	23	562	584	559	584	0.86
10	17	3.3	2.2e+02	2.6	1.0	2	23	620	642	619	642	0.95
11	17	0.0025	0.17	12.4	1.1	1	23	685	708	685	708	0.97
12	17	0.0063	0.43	11.1	1.6	2	23	856	878	855	878	0.96
13	17	0.11	7.6	7.2	0.1	1	23	884	906	884	906	0.92
14	17	1.3	92	3.8	1.2	2	23	914	935	913	935	0.93
15	17	0.3	21	5.8	1.3	1	23	1034	1056	1034	1056	0.94
16	17	0.018	1.2	9.7	0.0	1	23	1066	1088	1066	1088	0.96
17	17	0.00021	0.015	15.7	1.2	1	23	1093	1115	1093	1115	0.97

Sequence Information

Coding Sequence: ATGATGGCCTTAAAGATGTTGTATCGCGGCCCCAGTTCGCGTTTGgagaatttaattgaaaagatTCAAGCGACCAAGGAGATAACTAATAACGATATGTACAGCACGCACACTTCATCGAGCTATTCGCCCAGCATCTCGGATGGCACTTTGACGCCCAAttcacagcagccgcaaccgcagcagcagcaacagcagcagccgcagcctggCGAGGAGCCTGGCGAGGAGGCCAAGGCGAATGGGGAGGCGGCACAGCAAACGGAATTGGAGCAGGAGTTGAGCAAGCCGAAGCGTCCTGCACAactgcatcatcatcatcatcatcactatcatcatcagcaggcGCTGAAAATAGCGAACAAGCTGCGCAAAATCAATAAGGATGCAAAACTGGCTGCAGGAGGACAAGGACAAGGACATGGACATGGGCATGCCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGGCTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCCGAACATTTGCCATTCAAGTGCGAATACTGCGCGAAGCTGTTCAAGCACAAGCGTTCCCGAGATCGCCATAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCAGCTTTCTCCCGAAGCGATCACTTGAAGATTCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAATCGCGGCTATAACACGGCCGCCGCTCTGACCTCGCACATGCAGAAGCATAAGAAGAACGCCGCCATACTGGCCGCTGGCGGCAATCCGAATGCGCTCAACTATAGTCCGCGCTCCACGGGCTCCGCCTCGATCTCGAGCAATGGCAGCTTGCACAAGCGCCGCTATGCGCTGGCCCTCGCCTCTGATAGTAGTCCCAGTCGCTTGGAGTTTCCCAAGCGGGCGCGTGCTCAGTTggcggccacgcccacggcCACAACGATAGCGAcggcgacgccgacgccgctgctgcgctgcagctACTGTCCCAAGGCAACGGAGTTCAGCAGCCTCGAGCAGCTCAATGCGCATCTCCAGAGCAcacacgagcagcagcagcagcagcagcagcagccaaaggaTGCGGAGGGGCAGACGAATGGCTTTCAGCTGAGCTGCGAGTATTGCACGATGAAATTCGTGAATATCGCGGCGCTGTTCCAGCACATGAGAGTCACCCACTTGGACCGCTTGAGCAGTCCCAACTCCTACTACGAGCACTTCAATCGCCTGGGCTCACCGCAGTCTAAGCTCAAGGCGGACCTGGCGGCCGCCGAGAAGCCCGAGCAGGAGCTGCCCACGGACCTGAGCAGCAACAAGCGCCGTCCGCTGACATCgcccacacagcagcagcaacagcagcagcaacagcagcagccgcagccacagccgccgccaccgcctgGCATCTTCTTCTGCAATCAGTGCAACGCCGGCTTGCCGGACTTTGAGAGTTTTCGCAATCATCTGAAGAGCCACATAGCCGAGGGCATGCAGCTGATCTGTCCACACTGCGGCCTCAGTCTGCCCGAGCAGTGTGAGTACGAGCGGCACGTGGTCGCCCACTTTCTGATCAGCAGCTCGGAGTTCAACTgctgcagcgccagctgcgGCAAGTCCTATGCCAAGGCCGAGGAGCTGCATCAGCATCTGCTCGCCGAGCACGTGCAGACGATGCTCAAGTGTGCGCTGTGCTCGGAGCTGTGCGAGAATCGCATGGCGATGCAGCTGCATCTGGCCTGTGCGCACAGCCAGGAGTCGAAGCTGCTGCGATGCAGCGCCTGCCTGGAGCTCTTCCGCAACGATGCCGACTTCCATGTGCATGTGAAGACGCGCCATCAGCTGGGCAACCAGGGCCTGGGCAATCCGCCGGCGCCGACCAATCCGCTGCAGTGCATGTTCTGTCGCGCCGTCTGCTCGTCGGAGCTGGAGATGCATTTCCATTTGGCGGCGCATGCGCGACAATTCCGTTGCCCCAGCTGCCCGGAAACGTTCCACGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCACGGCGGCATCAAGGACAAGGAGTCACCCATTGCCGGCAGCATGGGCAGCTTcaacctGCACATAGACTACAATGTGGCCTTCAAGGGTCTCTTTGGCGGCAGCAATCCGCCGAGCAAGTTCTACCACAGCCCACTGCAGGTGGACACCAAACAGGCGCCGCATCCAGCACTCATGTACGGCCTGAGCCAGCGCTATTTGATGGAGATGTATGCGGCGAAGGCCAGCTCGCCGGCCAATGCCAGCGCAGCCGAGCTGCCCGCGCTCCCGGCCGTTCAGTCCGCGACAGGAAtaacggcggcggcagcgacgggcagcagcagcggcagcggcagcggcaacagctacagctgcgGCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAGCTGCACTCGCACCGCAAGCTCGCCCACAATCTGAAGACGGGCGTCAGTCTGAGGTGCGCCTACTGCTCGGGCAACTACAAGAGCCGCGCCGAGCTGGAGCAGCACATGAAGAGCTGCCACAATTCGAGCGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTCCCCTCGCCGGCCATACTCGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGCCAGTCCGGCAAGTGTGCGCACTGCGGCCACCAGCTGGAGCACGTGGCCGCCTTTCGCGCCCACCTGGGCGAGCACGGCAACGATGGCAATCTGCCGATGGCCTGCATCTGCTGCCGCCAGACGCTGCACTCGGAGTTCGAGCTGAGTCTGCACGCCAAGTTCCATACCAAGTCGCCCGGCTGCAACAGCCTGCAGGAGCCCGTCTGTGCCCTGTGCCTGGAGCCGTTGCCCGGCGCCGGCGAAACTGCCAAATTGTGCGACAAATGCTGTCGCAAGCACAATCTGAACGGCAAGCGCAAGGAGCAAGTGCAGCCGGCTGCAATAGCCACGCCCACGGCAGCCACGGCTGCGGCCAGTGCCTACATGGAGCATCGCTGTAATCTGTGCAAAATGATCTTGCCCCATGCCCAGAAGCTGCAGGAGCATCTCGTCGAGCACACGTTCGCGGGCACCGAGCAGCGCGGCTACAATTGCTACATCTGCTCGGCCGTCTTTACGGCGCCCGGTGGCCTGCTCGCCCACATAGCCGAGCACGGCACGCGTCCCTACGACTGCAATTTGTGCCCCGAGAAGTTCTACTTTCGCGCCGAGCTGGAGCATCATCAGCGAGCGCACGAGCTGcgcggcagccagcagccagcagcaattgcagccgcagcgcggCCCAAGCAGGAGGCTCACAGCTCGACGGCCAGCTCCCCCCTGACGCTCAGTCCCAGCCATGTCAAGCAGGAGCTGTACGAATCGGAGCCACCCACTTCGCCCAGCGCTGTCGAGCTGCCCGCGCCACAGGACGAGGAGGAGTACATCGAAGTGGAGCAAATGCCGCAGGAGACGCTGCGCACTGGCGAACTGCTAAGCACCGAGCGCTCCAGCAGCACCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQQPQPQQQQQQQPQPGEEPGEEAKANGEAAQQTELEQELSKPKRPAQLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGGQGQGHGHGHATAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARAQLAATPTATTIATATPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQQQQQQQQPKDAEGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNSYYEHFNRLGSPQSKLKADLAAAEKPEQELPTDLSSNKRRPLTSPTQQQQQQQQQQQPQPQPPPPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQCEYERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCALCSELCENRMAMQLHLACAHSQESKLLRCSACLELFRNDADFHVHVKTRHQLGNQGLGNPPAPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPIAGSMGSFNLHIDYNVAFKGLFGGSNPPSKFYHSPLQVDTKQAPHPALMYGLSQRYLMEMYAAKASSPANASAAELPALPAVQSATGITAAAATGSSSGSGSGNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGHQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPGCNSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRKEQVQPAAIATPTAATAAASAYMEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPGGLLAHIAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELRGSQQPAAIAAAARPKQEAHSSTASSPLTLSPSHVKQELYESEPPTSPSAVELPAPQDEEEYIEVEQMPQETLRTGELLSTERSSSTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: iTF_00502755;
80% Identity: -