Basic Information

Insect: Drosophila mettleri
Gene Symbol: salm
Assembly: GCA_035047625.1
Location: JAWNPI010000018.1:3116285-3123420[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 2.3e-06 0.00016 21.9 1.7 1 23 351 373 351 373 0.98

2 8 3.3e-05 0.0022 18.3 3.5 1 23 379 401 379 401 0.98

3 8 2.2 1.5e+02 3.1 2.5 5 23 643 661 640 661 0.84

4 8 3.4e-08 2.3e-06 27.7 0.2 1 23 667 689 667 689 0.98

5 8 0.001 0.069 13.6 0.9 1 23 699 721 699 721 0.98

6 8 0.051 3.5 8.2 0.1 2 23 935 957 935 957 0.96

7 8 1.1e-05 0.00075 19.8 5.0 1 23 1089 1111 1089 1111 0.96

8 8 8.8e-08 6e-06 26.4 0.7 1 23 1117 1139 1117 1139 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	2.3e-06	0.00016	21.9	1.7	1	23	351	373	351	373	0.98
2	8	3.3e-05	0.0022	18.3	3.5	1	23	379	401	379	401	0.98
3	8	2.2	1.5e+02	3.1	2.5	5	23	643	661	640	661	0.84
4	8	3.4e-08	2.3e-06	27.7	0.2	1	23	667	689	667	689	0.98
5	8	0.001	0.069	13.6	0.9	1	23	699	721	699	721	0.98
6	8	0.051	3.5	8.2	0.1	2	23	935	957	935	957	0.96
7	8	1.1e-05	0.00075	19.8	5.0	1	23	1089	1111	1089	1111	0.96
8	8	8.8e-08	6e-06	26.4	0.7	1	23	1117	1139	1117	1139	0.98

Sequence Information

Coding Sequence: ATGTGTTCAATATTTCGTAATCGCATCAATTACCGGAGCACAGGCACGCGCAGTGGCTCGACCAGCGCAGGCAGCTCGTCGGTTGCTGACCCAACcagcgacagagacagagacagggacagggacagcTTGCTAACCAAGGAGCTAAGTGCGGATAGCAATAACAATGGCAGTGCAGCCGATGAAACGCCAGATGCAGAGATGGAGCTACAGCTCGAGGCGGAACAGTCGTTGCCCTGCACTGATCAGCCGGAGAACAGCAATGAGGCGTTGGACTTGTCGGTAATCTCCGGCAGCCGTTTGCCCACGAGCGGGCATGTGGCACTAGAAGCTTTACAACATACCAAAGTGGCGGTGGCACAATTTGCGGCCACTGCGCTGGCGGGATCTGTGTCTGATCCGAGCGATCTGGCCATGGTGCAATCAACGATCTTCAACGTCCAGCGCCAGCATctgatgcagctgcagctcatccAGCACCTACAGAGTCAATTGAAGCGAGCGGGAGGTGTGGTAGCTGCGCTGAGCAGGCAAGGTTCGAGCTATGCTGAGCCTGAAgacgacgaggacgaggaggaggaACAGCCGGAACAGACGGACCAGCCACATCCTTCCAAAGAGCAGTCGATAGTCAACGGCGCGGCAGCAGAGGTCGATCATGAAAGGCTGGAGGAGAGTTCAAAGACTGAGGAACAGGAAATGTGCAAGAAAGTGGACGCAATATCGAATGAGTGCAATAGAGAACGAGACGTCGTATTGACCAAAGCAGAGCGGGAACGGGGGCAGGAGATTGAGGCTGAGGTGGATCAGGAGCTGGAGAGCGAATATAAGCCGATAATGTGCGACATCAGCTCCAGCCTGGCATCAAGTATAATCACCAATCACGACCCACCGCCGGCGCCCAATGAGCCGAACTGCCTTGAAATGCTGCAGCGCCGTACGGAAGAGGTCTTGGACTCGGCATCCCAGAGCTTGCATGCGGCCCAAATGCAGGAAGAGTACTCGGAGTATGCCTCTAAAGAAGCACAGAGTCGCGGCGAGATCTTCAAGCATCGCTGCAAATACTGCGGCAAGATCTTCGGCAGTTACTCGGCCCTCCAAATACACTTGCGCTCCCATACCGGCGAGCGACCCTTCCACTGCAATGTCTGTGGCAGCAAGTTTACCACCAAAGGCAATCTGAAGGTTCATTATCAGCGCCACACGCAAATCTTTCCTCccatgctgctgccgcctgtgGTGAATGGGGCACAGCCATCGCCGGCAGTGCCCGAGCAGTTTGGCACTCTCACACCCATACGGCTACCTTTTGCAACGCCAGCGCCCCTGGCGCCACCTCCACCGCCGACAGTGGGTCAACTCGGTAGCGAGCACTCAGCactagagcagcagcagcacgagctGGCAATGCCAGGACACCAACTACAGCAAGCTGAGGATCTAAGCAAGCCAGCCAGGGAGCTGGCGCATTCCCCCATGCAACCCGCGCAAACACCCAAGTCCCTGCCCGAGCGCAGCAGAAGTCAAAGCGTAGCGGATGCTGCTCAGCCGTGCTTAGCTCTGCCCGAGAgtaaggaaaaggaaaagttGAAGGACAGTCGCAAGTCCGCCACGCCACCAGCCACAACGGCGAACCGTCGTAATGGCAGCGTACGCAAGCGTCAGTCCAGCAACGGAGGTAGTCCGCCAGGTGAAGACCGTGAACAATCAGAGCATATGCAGTTAGTTAAGCTCGTGCGCCGTTCCTCGGCAAGCCGCGACGGCGCTGTCGCAATGCCAGGCGAGTACTCCCTCGCTCAGATGGAGCGCATCATAGACAAGTCGTGGGAGGATCTAATCGAGATCGATAAGACATCGGAGACATCAAAGCTTCAGCAGCTGGTGGACAACATTGAGAACAAGTTGACAGACCCAAACCAGTGCATCTTCTGCCAGAAGGTTATGTCGTGCCGCAGCTCTCTGCAGATGCACATACGCACTCACACTGGCGAGCGACCCTTCCGCTGCAAGATCTGCGGCCGTGCGTTTGCCACCAAGGGCAACTTGAAGGCGCACATGAGCATTCACAAGATCAAGCCGCCCATGCGCAGTCAATTCAAGTGCCCTGTGTGTCACCAGAAGTTCTCCAACGGCATCATCCTGCAGCAACACATTCGCATCCATACTATGGACGATGGAAGTGGCAACCAGGTGCATGGCCAGGGCCAGAGTCAAGGCCTTGGCGCTGGAGAAGCTGAGCGCTTGGGTATTGAGGATCAGAACTCTAACAAGTCAATGGGTACCTCTGACACTCTGGACTTCTCAACAACAATTTCGGATCATTCTGGCCAGAGATCGGAGTCCTCACAGGGAGGCGACTTCGATGAGTTCATGACCATGGACAGCACGGACGATTCCCGTGACAATTCAAGCGCAGCCACAACTACACTTCTCGACAGAGACAGACGGCCGGGCCAAGACGACGAGCGCTCCAGATCGGATCTGGATGGCGGTGGGCGTGAGAGCAACAGCGGCGAAATGCCCGCAATGGATCTTTCGTCGCCGTCCTCGTCGTCGGCATCGGCtgcagcggccgcagcagcagcggctgcagcgcgACTCTTCGGTGTTGGCAACagtacagcagcagctgctgctggtgctactGGAGCTCTGCCCATGCTTGGCATGCCCATGCCGCCGAATCTGTTGCTGATGGCCGCGGCGCGTGAGGAGATGCATGCACTAGGCCAGACGCATGCCAAGTTTCCATTACTGCCCTTCGGACCGCTCGGCTTAATGGGCCTGCAGCCGCCCCCAAATGTGTGCAACTTGTGCTTCAAGATGCTACCAAGCCTGGCCGCCTTGGAAAGCCATCTACAGAGCGAACATGCCAAAGAAATGACGGCTCCTTCCGCCCGAGCCCATTGCAACGAAACTGTATCTCCCTACGGTGCAAAGCTCACTCTCAATCCAAATCTATTTGCCAAGAAGCCGAAGCAGCCGCAGGAGCTGGCGCCAGCGGACCCAGTCACGCCATCGGCGGCATCCATTAAAGAGGAGCCTGACTCCGACCAACTGTTGGTCGACGAGGGTGGCTGCGACAGTGGAGCAGCTCCACCAGCTACCGGCTATCCGCATGAGCCACCCGGCGATGCGGAGCAGTCGCTGATGAAGATGCAGTTGCATGCTCATCGCTTTCCAGCTAGCCCGCTGGATTTTCAGCAAGCCTTGATGTCAGCCGGACCACCCAGTTCCAGTCTCGATCCGCCGGTGAACAACAAGCACTTCTGCCACGTCTGCCGGCGCAACTTCAGCTCGAGCTCAGCGCTGCAGATTCACATGCGTACTCATACCGGAGACAAGCCCTTTCAGTGCAATGTCTGCCAGAAGGCCTTCACCACTAAGGGCAACCTGAAGGTTCATATGGGCACGCATATGTGGACGAATCCTACATCTCGACGTGGCCGCCGAATGTCCTTGGAGCTGCCAATGCGCCCTGGACCGGGCCCGGGCACAACACATGGCGCGCCCTCCGCTGAGCAGGAGTTCATGCAACGCCGACCGGAACTCTTTTTTCCCTATTTGCCACCCTTCTTCAACGGAATTCCACCCAAGCCCGGCGAGTTGAGTCCTGGTGCGTTCGCCAACATACCTCCACCGCACTTTGCTAATGGAGCTAAATATCCGTATCCGCCTGGGCTGCTGGGCTTCCCAGGCTTCTTGGGTGGGGCTGGGGTCCATCACCAATATCCGCATGGAGCGGAGAGGAGTAGCAGCAAGTCGCCAACATCTGAGCCTGCGCAGAGTCCAGCATCCCGGGAGGACGACGGAGCGCTAAGTAGTAATATTTGGCATCCGCTGAATAGCATTAAGATGGAGAACAATCAAAACGAGAATATTGGCAATCAGGGCGAGCTGGAGCAGGAGGATATCGCTGGCACAGATGGGGACGCTGAGCCCGAGGCTGGAACCGGTTCCGGGGCCggggctggagctggagctggaggtgACGAGTCTGGTTCGGGCTCGGGCTCCCGCGGCTGCGAGAAGTAG
Protein Sequence: MCSIFRNRINYRSTGTRSGSTSAGSSSVADPTSDRDRDRDRDSLLTKELSADSNNNGSAADETPDAEMELQLEAEQSLPCTDQPENSNEALDLSVISGSRLPTSGHVALEALQHTKVAVAQFAATALAGSVSDPSDLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAGGVVAALSRQGSSYAEPEDDEDEEEEQPEQTDQPHPSKEQSIVNGAAAEVDHERLEESSKTEEQEMCKKVDAISNECNRERDVVLTKAERERGQEIEAEVDQELESEYKPIMCDISSSLASSIITNHDPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYASKEAQSRGEIFKHRCKYCGKIFGSYSALQIHLRSHTGERPFHCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPVVNGAQPSPAVPEQFGTLTPIRLPFATPAPLAPPPPPTVGQLGSEHSALEQQQHELAMPGHQLQQAEDLSKPARELAHSPMQPAQTPKSLPERSRSQSVADAAQPCLALPESKEKEKLKDSRKSATPPATTANRRNGSVRKRQSSNGGSPPGEDREQSEHMQLVKLVRRSSASRDGAVAMPGEYSLAQMERIIDKSWEDLIEIDKTSETSKLQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPPMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSGNQVHGQGQSQGLGAGEAERLGIEDQNSNKSMGTSDTLDFSTTISDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSAATTTLLDRDRRPGQDDERSRSDLDGGGRESNSGEMPAMDLSSPSSSSASAAAAAAAAAAARLFGVGNSTAAAAAGATGALPMLGMPMPPNLLLMAAAREEMHALGQTHAKFPLLPFGPLGLMGLQPPPNVCNLCFKMLPSLAALESHLQSEHAKEMTAPSARAHCNETVSPYGAKLTLNPNLFAKKPKQPQELAPADPVTPSAASIKEEPDSDQLLVDEGGCDSGAAPPATGYPHEPPGDAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPSSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPGPGTTHGAPSAEQEFMQRRPELFFPYLPPFFNGIPPKPGELSPGAFANIPPPHFANGAKYPYPPGLLGFPGFLGGAGVHHQYPHGAERSSSKSPTSEPAQSPASREDDGALSSNIWHPLNSIKMENNQNENIGNQGELEQEDIAGTDGDAEPEAGTGSGAGAGAGAGGDESGSGSGSRGCEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00475377;
90% Identity: iTF_00559655;
80% Identity: -