Dmet007833.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mettleri
Gene Symbol
-
Assembly
GCA_035047625.1
Location
JAWNPI010000085.1:1770599-1772689[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.37 25 5.5 0.3 1 16 38 53 38 55 0.82
2 10 0.0032 0.22 12.0 2.9 2 23 221 242 220 242 0.97
3 10 0.00046 0.031 14.7 1.2 1 23 268 289 268 289 0.97
4 10 0.00063 0.043 14.2 1.0 1 23 295 317 295 317 0.95
5 10 0.00013 0.0089 16.4 0.4 1 23 342 364 342 364 0.97
6 10 8.5e-08 5.8e-06 26.4 0.9 1 23 370 392 370 392 0.99
7 10 0.0014 0.096 13.1 5.5 1 23 398 420 398 420 0.98
8 10 3.3e-06 0.00022 21.4 0.8 1 23 426 448 426 448 0.98
9 10 2.1e-05 0.0014 18.9 0.1 1 23 452 474 452 474 0.99
10 10 0.0092 0.63 10.6 0.0 3 23 498 519 496 519 0.95

Sequence Information

Coding Sequence
ATGTCAGGCGCCAGGGGTAAACAACACGGGATAGCTGCGAGCTCGCACGTGGacgaacaaaaacaaagcaatactGACCATTTCATAATTGATACGTGTGCagatgaaatttattattgtgaaGATTGTAACGAGGACTTTGACAGCATCGAGTCGTACAACCGGGCGCACAGTGGCCCCAACGGCTGTGCGGGTACTGTCGATGACAGATCCAAATTTCAGTTTTACGCTGCCGAGATCAAAGATGAGTTAGAGGACAACACGATAGATATTGATCCCATGATAGTTGAAGATGATTTGATCGAGGAGCTAGACGAGGCAAGCGAACCGCAGATGTGGGAGGTGCTGGACGACGACGAGCAAGTGTACATAACTGAAGCGGATTTTCACAATGAGCCTGAAATCGAGGCACAAACTGAGCCGGAGCCAGAGGCAGAGGATGTGGCCAATAAATCTGAACGTTACTTCTGTTTCGATTGTCACAGCATTTTTGAGACACGCCAGAGCGCCGAGGACCACAGTTGCCCACAGGCCGAAACGAATGGCGAAtcaggtagcaaaaacaataacgcCAAGCTGGCCAAGACGCAGACACCAATGCGTCGCAAGGTCACAGCCACAGCGTctagcagcaataataacagcagcagcaccaccacagTTTGTGACATTTGTAAAACGCAATTCAGCTCGGCGAAATGCCTTAAATTCCATATGCGCATTCACAACAAGCGTGCGCCCAAATCCATACAGGATGCCCTGCCTGTGGGAGCGCATCAGCAATACAGCGAGTTGGATCAGTTCTACTGTGAGATTTGCAACAAGAGCTTCGAGCAGAACCTGTTGACTGTGCACAAGCAGATGCATCAGAGCCAGGAGCAGTTCTTGTGTGGCACTTGCAATCgaaaatttgagaatttgaCCAACTACGAGATGCATTTGAAAATTCATGAACGCCATGCGCTGAACGGCAATAGCAGTGCGAATAAGAAGCCCGCCGGTGTGAACAAGGATAAGCCAGGATTCGCCTGCCAATACTGTCAGCGTGTCTTTCCCCGCCCCTACGAGAAGGTGAAGCACGAGCGTGTCCATACCGGCGAGAAGCCCTACAGTTGCGAGGTGTGCGGCAAAACGTTTCGCGTCTCCTACTCATTGACGCTGCACCtgcgcacgcacacaaacatacggCCGTACGTGTGCACCACGTGCAACAAGCGCTTTAAGTCGCATCAGGTTTACGCGCATCATTTGCGCATTCACAGCTCGGATCGTCTGTATGTCTGTGATAGCTGCCCGAAATCGTTTCGCACTTCTGTACAGCTCTACGCCCATAAGAATACGCACACGAAGCCGTATCAGTGTGCCGTCTGCAATCGTCCGTTTGCCTCGCTCTATGCCGTCAAGGCGCACATGTCGACCCACAGGACGAGCGACGCGAAGAGCATCAGCGCCGGTGCCTCCAAGAGTCAGCAGCTGGCGAACAAATATTGGTGCGTCACTTGCGGTGCGGAGTATGAGCGTCCATTTGCTCTGCGTTTACATATGAAGGCCGCCCATGGTCATCCGGATGATGCGGACACACGATTAGCCAAAGTGCCTGCTCCAgaagatgacgatgacgacgacggcaACGAGGAGATTATTGTTCCAGACACCGAGACGGCGGTGCTCATCGCAGCCGCCAAGGCGGATTCAGCCTATCTCGATGCAGCCGCCAATGATGTGGACGTAATGGGGGCCGTGCCCAAGTACGAGGAATGCATTGAGGTATCCACAGATGCGTTCGATGTGGAGACATTCCACAACGAGGAAATCATCACAGACTGGCTGAAGTGA
Protein Sequence
MSGARGKQHGIAASSHVDEQKQSNTDHFIIDTCADEIYYCEDCNEDFDSIESYNRAHSGPNGCAGTVDDRSKFQFYAAEIKDELEDNTIDIDPMIVEDDLIEELDEASEPQMWEVLDDDEQVYITEADFHNEPEIEAQTEPEPEAEDVANKSERYFCFDCHSIFETRQSAEDHSCPQAETNGESGSKNNNAKLAKTQTPMRRKVTATASSSNNNSSSTTTVCDICKTQFSSAKCLKFHMRIHNKRAPKSIQDALPVGAHQQYSELDQFYCEICNKSFEQNLLTVHKQMHQSQEQFLCGTCNRKFENLTNYEMHLKIHERHALNGNSSANKKPAGVNKDKPGFACQYCQRVFPRPYEKVKHERVHTGEKPYSCEVCGKTFRVSYSLTLHLRTHTNIRPYVCTTCNKRFKSHQVYAHHLRIHSSDRLYVCDSCPKSFRTSVQLYAHKNTHTKPYQCAVCNRPFASLYAVKAHMSTHRTSDAKSISAGASKSQQLANKYWCVTCGAEYERPFALRLHMKAAHGHPDDADTRLAKVPAPEDDDDDDGNEEIIVPDTETAVLIAAAKADSAYLDAAANDVDVMGAVPKYEECIEVSTDAFDVETFHNEEIITDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00493819;
90% Identity
-
80% Identity
-