Dmet002987.1
Basic Information
- Insect
- Drosophila mettleri
- Gene Symbol
- -
- Assembly
- GCA_035047625.1
- Location
- JAWNPI010000035.1:10035787-10040414[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 24 0.0024 0.16 12.4 1.5 1 23 216 238 216 238 0.97 2 24 0.01 0.7 10.4 2.0 1 23 244 266 244 266 0.97 3 24 0.31 21 5.8 0.8 2 20 298 316 297 319 0.93 4 24 7.1e-05 0.0048 17.2 2.2 1 23 396 419 396 419 0.94 5 24 0.31 21 5.8 1.0 1 23 459 482 459 482 0.96 6 24 2.6 1.8e+02 2.9 1.8 2 23 494 515 493 515 0.96 7 24 0.042 2.9 8.5 0.9 1 23 595 618 595 618 0.96 8 24 0.0033 0.22 12.0 0.1 3 22 629 648 627 648 0.95 9 24 0.83 56 4.4 2.8 1 23 657 680 657 680 0.96 10 24 0.001 0.071 13.6 0.2 2 23 708 729 707 729 0.97 11 24 0.00024 0.016 15.6 7.9 1 23 737 759 737 759 0.98 12 24 0.0033 0.23 12.0 0.5 1 23 908 931 908 931 0.95 13 24 2.6 1.8e+02 2.9 1.7 1 23 968 991 968 991 0.88 14 24 1.1e-05 0.00072 19.8 1.9 1 23 1016 1038 1016 1038 0.97 15 24 0.0011 0.073 13.5 2.4 1 23 1045 1067 1045 1067 0.98 16 24 0.016 1.1 9.9 0.0 2 21 1094 1113 1093 1114 0.93 17 24 0.09 6.1 7.5 4.0 1 23 1159 1182 1159 1182 0.96 18 24 0.007 0.47 11.0 0.9 1 23 1219 1242 1219 1242 0.95 19 24 0.0039 0.26 11.8 1.4 1 23 1270 1293 1270 1293 0.97 20 24 1.3e-05 0.0009 19.5 0.1 2 23 1321 1342 1320 1342 0.95 21 24 4.5e-05 0.0031 17.9 2.9 1 23 1348 1370 1348 1370 0.99 22 24 2.2e-06 0.00015 22.0 2.0 1 23 1376 1398 1376 1398 0.97 23 24 5.7e-08 3.9e-06 27.0 2.4 1 23 1404 1426 1404 1426 0.99 24 24 0.00011 0.0077 16.6 0.6 1 23 1432 1454 1432 1454 0.98
Sequence Information
- Coding Sequence
- ATGTTACCAACGGATATTTGCCGTACGTGCACACTACATAATGATAGACTGCTTCCGTTAACCACGTGTACtgataaatatgcaaataaatgcttACATGATATGTTGCACGAATTGACACAAAATGATCCATTGCAGGAGCATACGGATGACCGGCTGCCACAGCACTTGTGTATCGCCTGTCTGCACAAACTGGAGGCTGCCTATGCGTTCGTGCTGCAGGCGCGCCAGGCTCAAGAGGAActtttgttgcagttgcaaaaaGGCTTGCAGACCCAGTGCTTGGATGAGATGCCTATAGACATTGACTTGCAGCACATCAAAACCGAAACTATTGTCGACATTCATCTAAATAGCAAAACCAAAAGTGAAGACGATGAGGAAGCTGAAGACATGTCTGCAGTGTCTATTCCAGTCCTAAAATGGCAGCCAGAAAGCGAAAGTGAGAGCGATAAGACTGCTGTTGATGACCAGGGCGAAGACTTGAAGCCTACGCAGTTGCGACGAAGTGCACGTAACCCTAAAGTAGACATCTGCAGCGAAATTGAGGCATCATCTGCTCATCTGGATCCTTTGCCAATCAAACGACGTCGAGGTCGCCCAGCTCGTTTTTGTAAAAAGGAAACTATCAACGACCAGGGACGTCATGTGTGTGAGGTTTGCGGAAAGACTTTTTCGTGGTTCCGCGATATGCAGCGCCACTCGCGCATACACTTCGATCAGGCGACCTATGTGTGTGAGACTTGTGGCAAAAGCTTCTTGCGCAAAGACAAATACATGTTCCATCTGCGCTCTCACGAAAAGCGTGCATCCAAGTGCCAGGCCACGCAAATGAGCAGCGAATGGCGCTTCGCTGAGCGTCTCTACAGCTCTGGTCGACTCAAGCGGGTGGAATGCAAACTATGCGGATTGAAATACCAGCGCATAAACGAGCTGCGCGAGCATCTGGCGTGCCACAACAGCATTGAGAGTCTGTCCCATCTGAGTCTAGAGAGTGATGTTGTCAAGGAACAGTTTgcaacagagcagcagcagttagAATTGTCGCTCATTAAGCAACAGATATGTGCAGAGGTTGCAGAAGGGCGTCATCACCTGGACAAATATTGCGCTGTCGTCAATGCGTATGGTTATGAGCTCAGTCTTAGCGACTCAGACGAAGAACCTTCTGGCAGGCTGCCGCAATACAAGTGCCAGCAGTGCAACATAAGCTTCACGCGCAAATATCGCCTTATGCGTCACACCCTCGAGGAGCACACCAATCCGGGCACAGATGTTTCATGGCAGCGCTGTGATGCTTGCCAAATTGCCTTTGTGTGTGACAATATGTTGGAGCAACATCAGCGTACGCAGTGCCACAACAAAATGAAGCGTTACACTTGCTCCAACTGCCCAGGAAAATTTATTTGGCTGCAGAATCTGGAGCGCCATGCGTGTTCGCAGCACATCAAACAGAAGCAGGAGAACCATCAACAAAAGCAGTGTTGTCTTTGTGATGTCCTCTTAAATAGCATGTTCGAATTACGAACTCATTTGCTCACTCATCAAGATGGACGCAGCGGCATATATCCAGAGCGGCAGGCGACTTTCTTTCGTACCTACTATCCCAATGGCCTTGACTGCACCATGTCAGAGCTAAGCGCACGCATTGCCGCCGACTTTCAAGTGGAGGATTATGGGCGATACTTTAACGCCAGAACGAAAAATGGCGAAGAGCTCGACTTCTTTGCTTCGGACTCGGATTTCAATGACGCAGACCAGTTGACTTCTGGCCCTACGGTGCACATATGTTCCCTGTGTGGCGAGACGGCAATGCGCCTGACTAAATTGCTCGAGCATCAGCGCAGCCGGCATAGCGATGTGCAGGACAGGCTGCCATACGGCTGTGGCGATTGTGATTTGAGTTTTGTGGCCAATTCGCTGCTTCAACAGCATCGCCGACGCGTCTGCGCCAAGCAGCATACCAAGTACCATTGTCTGCAATGTAGTCAGCGCTTCTACTGGCTGTCCAATTACGAGCTGCACATGCAGCTGTATCATCAGAATCCTCCAAGGGAGGATGATGAAGATGAACACGAGACGCGGATGAGAAGCAAGCGCCAGTCAACAATGGCCAAATTGCAGTGCGGCGAATGTGAAAAGGTGTTCATCTGGCCCAAGGATCTGACGCGTCATAAGCGTTTGCATCAACCTTGGTCCTTGGCCCAATACCATTGCTTGCACTGCGACCGCAAGTTCCATCGTAAGGATGGGCTCAAGTCGCATATGCGTGTGCACGGCGAACAACAGGTGGATGTCACGGCTGCCAATGAACAAGTGGTACCCACGCTGCAGCGAATGCCAGTGGTCCTGACCCAGCTATGCCGACCCAATGGCTGCAAGCAAATTCAATGCATGATATGTCTCTCGAGGCACACCAAAATATCTGATATTCGCTCGCATTTGTTTAAGCATCAGCATGATGTCAAATTTACAGAAGAGAGGGGCCAACCGGAAAGTATTGCGAGCATTGCACGTGCTCTATATCCAGAGCTGGCTGTACctttggagcagcagcaacttgttGAGCGCATTCAAAGTGATGTAGCAAAAGGTGTGCAGCTGGACAGATTCGTATCCATTACAAACGAGGCGGGAACTGAGCTCAGCCTGGACAGCAGCGAAACGGAAACTGATTCCGACTCTGCAGAAGCGGTCGAAAGCAAGTCGAACAAGCAATCCTATAGCTGTGAGCTGTGCCAGCTCAAGGTATCGCGCAAGTATGAGCTCTATGCCCATCAGCTGGAGCAGCATACGTGGGACCAGGCAACACGTGTTTGCAACTGTTGTCAGGCCCGATTCGTGAGTGAGCAGCTACTAGAGCACCATTGTCGCACAGTCTGCAGCAACGCTCAGAGACGTTTCTGCTGTCGTAAATGTCCGCTACGCTTCCAATGGCGCGAGAATCTTAAGCTGCATTCTGACGTGGCGCACAACGAAGCTAAAGATGAGCAACCGAACTTGGCCTTGAGATTGAACGGGACGCACCTGTTGCCCATCGTTAGTTATGACTGCACCGAATGCAATCGAAGCTTTAAAATGCAGAAGGATCTCACCAGACACACTCTGATGCACGCCCAGGACTCAAACATTTATCGCTGTCGCTGGTGCGCACGACGCTTCTATCGCCATGCCAATCTTCTGCAGCACATTGAGCGTCACGGTATTAGCGCCGAGCAGCTGCCCTATGCTGAGGCACTGCTGAATGCCAGCCGACATCCTCATGGCCAGAAGTGCATCCAGTGTAAGGTCTGCAACTTGAGCTACCCCACCATTGCAGCGTTGCGCGCTCATCTTCTGTCAGCGCCAGCAGGCTCACATCATGAGTTTGACTCGTTGCTCAACTACTCTATTACTAATCAGTTGGGGtatgagctgcagctggacgaCTCGGAAACTGATGAGGAGGCCAAGCCGCCAGGCACACCCAAGCACTACACCTGCGGCATGTGCCAACTGCGCTGTGTGCGCAAGTATGAGatgcatcagcatcagcaggcGATGCATCGATTGGAGCGAATAAAAGACGGATGTGATTTGTGCGTCTATAAGAGTGTCTCACCAGATCTCATTGCCTATCATCGCCGCACTTTGTGTGACAATACGGAGAAAAAGTTCAAGTGCTCCAAGTGTGGCTATAAGTTTATGTGGGAAACGAATTTGTTGCAGCACATGGAGTTGCAGCATCCAAGCACCGAAAGCAGTGAAAGGCAGCAGGATGGAAGCTGTCGTCCTGCACAGGAAGTGCCCAGTGCAGAGTGCCAGATTTTTCAGTGCGGCCAGTGTCCTAGTAAATACAATCGCAAGGATCGGCTCACAGCACATGTAAAGAAATATCATGTAGCGGGAGCAACTGGATCCACCTCTGCGGCAGCGAAGGCTATGAAAAATTCAACTGATGCCAAGCAacagaaaagttttttatgcGCCTTCTGCGGCAAGGCGGTTAGTTCCTCCTCTAATCTAATCATACACATACGTCGTCATACTGGCGAGAAGCCTTTTAAGTGCGACTACTGCGATATGGCTTTTCCACGCTCTTCCGATCTGCAGTGCCATCGACGCACCCACACGGGCGAGCGGCCTCACGTCTGCACGGTTTGCCAAAAGGGCTTTGCTAGATCCTACAAGTTGCAGCAACACATGCGCATTCACAATGGCGAACGACCATACAAGTGCACTTATTGTGACAAGAGCTTTACTCAGTCGAATGATCTGACGCTACACATACGTCGGCACACAGGCGAGCGTCCCTACCAGTGCAATACATGCGGCGAACGCTTCATTCAGGGGACAGCCCTAAAAAATCATCGCATGCAGCATGGACATCACGATGCGGAAGTGGAGCAGGCAAAGATTACTAATTAA
- Protein Sequence
- MLPTDICRTCTLHNDRLLPLTTCTDKYANKCLHDMLHELTQNDPLQEHTDDRLPQHLCIACLHKLEAAYAFVLQARQAQEELLLQLQKGLQTQCLDEMPIDIDLQHIKTETIVDIHLNSKTKSEDDEEAEDMSAVSIPVLKWQPESESESDKTAVDDQGEDLKPTQLRRSARNPKVDICSEIEASSAHLDPLPIKRRRGRPARFCKKETINDQGRHVCEVCGKTFSWFRDMQRHSRIHFDQATYVCETCGKSFLRKDKYMFHLRSHEKRASKCQATQMSSEWRFAERLYSSGRLKRVECKLCGLKYQRINELREHLACHNSIESLSHLSLESDVVKEQFATEQQQLELSLIKQQICAEVAEGRHHLDKYCAVVNAYGYELSLSDSDEEPSGRLPQYKCQQCNISFTRKYRLMRHTLEEHTNPGTDVSWQRCDACQIAFVCDNMLEQHQRTQCHNKMKRYTCSNCPGKFIWLQNLERHACSQHIKQKQENHQQKQCCLCDVLLNSMFELRTHLLTHQDGRSGIYPERQATFFRTYYPNGLDCTMSELSARIAADFQVEDYGRYFNARTKNGEELDFFASDSDFNDADQLTSGPTVHICSLCGETAMRLTKLLEHQRSRHSDVQDRLPYGCGDCDLSFVANSLLQQHRRRVCAKQHTKYHCLQCSQRFYWLSNYELHMQLYHQNPPREDDEDEHETRMRSKRQSTMAKLQCGECEKVFIWPKDLTRHKRLHQPWSLAQYHCLHCDRKFHRKDGLKSHMRVHGEQQVDVTAANEQVVPTLQRMPVVLTQLCRPNGCKQIQCMICLSRHTKISDIRSHLFKHQHDVKFTEERGQPESIASIARALYPELAVPLEQQQLVERIQSDVAKGVQLDRFVSITNEAGTELSLDSSETETDSDSAEAVESKSNKQSYSCELCQLKVSRKYELYAHQLEQHTWDQATRVCNCCQARFVSEQLLEHHCRTVCSNAQRRFCCRKCPLRFQWRENLKLHSDVAHNEAKDEQPNLALRLNGTHLLPIVSYDCTECNRSFKMQKDLTRHTLMHAQDSNIYRCRWCARRFYRHANLLQHIERHGISAEQLPYAEALLNASRHPHGQKCIQCKVCNLSYPTIAALRAHLLSAPAGSHHEFDSLLNYSITNQLGYELQLDDSETDEEAKPPGTPKHYTCGMCQLRCVRKYEMHQHQQAMHRLERIKDGCDLCVYKSVSPDLIAYHRRTLCDNTEKKFKCSKCGYKFMWETNLLQHMELQHPSTESSERQQDGSCRPAQEVPSAECQIFQCGQCPSKYNRKDRLTAHVKKYHVAGATGSTSAAAKAMKNSTDAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRMQHGHHDAEVEQAKITN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00509945;
- 90% Identity
- -
- 80% Identity
- -