Basic Information

Insect: Drosophila merina
Gene Symbol: -
Assembly: GCA_035047645.1
Location: JAWNPH010000055.1:3879767-3891062[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.2 1.1e+02 3.8 2.8 3 23 286 308 284 308 0.92

2 15 2.6 2.4e+02 2.7 1.1 3 21 450 468 448 472 0.90

3 15 0.28 26 5.7 0.5 2 23 494 516 493 516 0.88

4 15 1.4 1.3e+02 3.6 3.0 1 23 533 556 533 557 0.94

5 15 0.21 19 6.2 0.3 1 22 561 582 561 585 0.90

6 15 0.00038 0.035 14.8 0.2 2 23 630 652 629 652 0.95

7 15 0.32 30 5.6 0.7 1 22 657 678 657 678 0.93

8 15 4 3.7e+02 2.1 3.3 1 23 698 720 698 720 0.93

9 15 0.00012 0.011 16.4 3.3 1 23 732 753 732 753 0.98

10 15 7.4e-06 0.00068 20.2 0.3 1 23 759 782 759 782 0.97

11 15 0.00035 0.032 14.9 0.5 1 23 806 828 806 828 0.98

12 15 0.52 47 4.9 1.4 1 23 836 860 836 860 0.95

13 15 0.031 2.9 8.8 0.9 1 23 865 890 865 890 0.97

14 15 1.2 1.1e+02 3.8 2.1 1 23 900 922 900 922 0.96

15 15 0.00016 0.015 15.9 3.3 1 20 928 947 928 949 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.2	1.1e+02	3.8	2.8	3	23	286	308	284	308	0.92
2	15	2.6	2.4e+02	2.7	1.1	3	21	450	468	448	472	0.90
3	15	0.28	26	5.7	0.5	2	23	494	516	493	516	0.88
4	15	1.4	1.3e+02	3.6	3.0	1	23	533	556	533	557	0.94
5	15	0.21	19	6.2	0.3	1	22	561	582	561	585	0.90
6	15	0.00038	0.035	14.8	0.2	2	23	630	652	629	652	0.95
7	15	0.32	30	5.6	0.7	1	22	657	678	657	678	0.93
8	15	4	3.7e+02	2.1	3.3	1	23	698	720	698	720	0.93
9	15	0.00012	0.011	16.4	3.3	1	23	732	753	732	753	0.98
10	15	7.4e-06	0.00068	20.2	0.3	1	23	759	782	759	782	0.97
11	15	0.00035	0.032	14.9	0.5	1	23	806	828	806	828	0.98
12	15	0.52	47	4.9	1.4	1	23	836	860	836	860	0.95
13	15	0.031	2.9	8.8	0.9	1	23	865	890	865	890	0.97
14	15	1.2	1.1e+02	3.8	2.1	1	23	900	922	900	922	0.96
15	15	0.00016	0.015	15.9	3.3	1	20	928	947	928	949	0.95

Sequence Information

Coding Sequence: ATGAATCCAGACGACCTGGACGACACCCACTTGTGCATAAAATGCAATGCCACAATTTTGGGACTGGAAAAGTATATCGAACACCGAAAACAAAACTGTTTGATTCCCGAGAAACGGACAGTGACTACCACATCGGAGAGTCCTTCCACCACAGCAACTAGCACCCAAGTTTCCCCAAATAGTATCAGTCGCGGGAACTTGGATCACAGCTACGATGGCTTCCATTTTGCAGAACCGGAAGCTCCCAGCAGCTATTTGAGGAAAACAGCAGCGAGTCATGGCGGAAAAACGTCAAAGTCCCTGACCGAAGCCTACGATCTGACCTATGAACTGGGAGCAGATTTGTTCTTTTCGTCGCTGCAGTTGCAGAGTGTTTCTACGGGTGGGAAGACAGGGTCTGGGGCACGACAGGAGAGGTCGAAGGAGGATCCATGGCACCCGGCACCCGGTAGAGATCCTTTGCTGAAGGCTGTGCGGGAACACGAAGTCACTGGTTTTAAGCCACTCAGTTTCGACCACGACTCTCCGGAAGTCAGCGAGGAGGATGACGAGGAGGACGTTACCTACGAGCCGGAATCGGAGGAGGATGAAGAGGAATACGATACGAGGCGTCATTCGCCACCGACTGTGCCCGCCACTCACACCGGCGGCAAGTGGAAGCCCGAACACCGTCCCCAACTCCGGCATCCGCACATCGAACGGATCTCGCCCAGCTGGGATGAGCCACCCGAGGAGACGTACACCCACCCTCCGGCGGATCACACCAAAGGCAAGTGGGTGCCCGGCAGCAAGCAGTTGGAGTACCGCGAGAACATAGATCTCACCAAGCTGGAGCAACCGGGGACCAGCTACTGGTGCAACATCTGCTGCAGACGTTTGAAGAGTCGCTTCAACTACGAGCAGCATTTGCGAAGCGGCTACCACTTGAAAAGGGCAGAAGCCGAGTGCCAGTTGGAGCAGGCCACCTTGGGCAGAGAGCTCAGCCTGAGTAAAGAGTTCGCTGTGGAGGTTAAGGACAAGGAAAAGGATTCGCCAAAGCCtcgaaagagacagagacgaGCCAACTTCCTGCGCTGTGATCTTTGCCGGCACACAATGGCCCGCCACTTGATGGGAAAGCACCTGATCTCCCACTATCACTACCGGCgcttgcagcagcaacagaatcAACTGAAGAGACAGGCATCCCTGCAGGACGTCCTCACCCACATGGACAGCATTGTGAGGCAATCTCCATTCCAGTGTCTGCCCTGCAGATTTTATGCCAACACGGAGGAGGCCTTCCTTGACCATTGGCAGTCGAAAGAACATTCCGAAGTCACCCAGAAACTGGGAGGTAACTTCTGGTGTGGCTACTGCCAGTTCGAATGTGCCAGTAACGACGAGATGTGGATGCATCTGCTCCATGCATCCCACAAggaagtgctcctggccctgAATCGATCTGTTCCCATTTGCATAGCCCAGAGAAGGCATCTCGTGTGCTCCAGTTGTGGTCTCAGTTTCCTGTACAACTTCCAATTGCGTCAGCACTTTGGATCCGAACATCCTGGCCAGGCTGCCACTGAAACTGCTGCGGATGAGTACCAGTGTCGCTTCCGATGTGGTTTGTGTGGCATGCCGCAGAAATCTCGCCTAGCCTTGCAACGTCACGAAAAGCACAAGCACCATGTGGCCAGGTACTACTGTGCCATTTGCCGACTGGAGTTCGAGACTCCTCTGGAGGCGCGACGCCACCGGAATCAGATGAAACACAAACTGAAGGCCAGGCCAAAAGCGTCTAGGTCTCACCTAGAAAAAGAAATTGAGAGCATGCTAAGGGAAGTTCTGGATGAACCGACTGAGCCAAGTGGCAATCCCTCGAAGAAAACTAAAATAGTCAGCCAAAAATGCTCCAACTGCGAGGAGGTTTTCGAGTCTCCTCAAGATTTAGCCCGACATCGAGCTAAAGAGCATCCTGGGGAAAACCATGTTTGTCTCAGCTGTGGTCTAAGCTTCCAATCCACTCAAGCTTTTGGCAGGCATACACGGAAATGTCAACCCTTGGCCAGCACATCCTCCTCGGCGCCGGAAGATCCCAAGAACACGACCTTCTCCTGCTATCAGTGCCCATTCCGTTCCCAATTCAAGTCCGATCTTATTTATCATCGATTTTTCCACACGCGTACAGGGAGTATTTCCAAGCACGAAATCTTCAAATGTCCTCTCTGTCCTAAACAGTTCAAAAAGCATTCGCTTCGAGCTCATCTTAGAAATCACACAAACGAGAAGATCTTCGAGTGTCCCGAGTGCCCAATAAAGTATGCCAGAAGACACAACCTGAAGGATCACATCGACACAGTTCATCGGAAGAAGGAGGATCTGGAAGCGACgaaattggccaaaaagaaagaaaccgCCAAAGAAAAAGCCAAATATCAGTGCGGAACCTGTGGAAAAATCCTTGTTAAAAAATACACCCTAAAAATACACGAACTGAAACATAAGGAGCAGTTGGAGAGGAATTTCAAATGTCATTTTGCGAACTGCTCCTATGCTGGCTTGACCCAGGATAACCTCAAGACCCATCTGGTCTCGCACTCTCAAGGGAGTTACAAATGTGACCGGGAAAATTGTGCCTATGTTGGCAAAAGCGAAATCCATCTTAAGAGACACCTCAAGTCGGCCCATCCCGCGGAGAAGGATGGCGGGCAGTGGTACTCGTGCGATCAGTGCGAGTTCAGGGCCCGCATCAAGGGCCACGTCCGCCGGCACTCGCTGCGCCACTCGGGCCAGACGCCCCACCAGTGCCCCCACTGTGACTACAAATGCAGCACCATCGACAATTTACGCAAACACATCGTCAAGACTGGCAAGCATCCCGGAAAGTTTCTCTACGAGTGTGGAAAGTGCAGTGACCAGGAATCAGTCGACATCTTTAAAACAAACAACTACAAGGACTACCAGAAGCATTTGGATAGCCACAAAGTAAACTAA
Protein Sequence: MNPDDLDDTHLCIKCNATILGLEKYIEHRKQNCLIPEKRTVTTTSESPSTTATSTQVSPNSISRGNLDHSYDGFHFAEPEAPSSYLRKTAASHGGKTSKSLTEAYDLTYELGADLFFSSLQLQSVSTGGKTGSGARQERSKEDPWHPAPGRDPLLKAVREHEVTGFKPLSFDHDSPEVSEEDDEEDVTYEPESEEDEEEYDTRRHSPPTVPATHTGGKWKPEHRPQLRHPHIERISPSWDEPPEETYTHPPADHTKGKWVPGSKQLEYRENIDLTKLEQPGTSYWCNICCRRLKSRFNYEQHLRSGYHLKRAEAECQLEQATLGRELSLSKEFAVEVKDKEKDSPKPRKRQRRANFLRCDLCRHTMARHLMGKHLISHYHYRRLQQQQNQLKRQASLQDVLTHMDSIVRQSPFQCLPCRFYANTEEAFLDHWQSKEHSEVTQKLGGNFWCGYCQFECASNDEMWMHLLHASHKEVLLALNRSVPICIAQRRHLVCSSCGLSFLYNFQLRQHFGSEHPGQAATETAADEYQCRFRCGLCGMPQKSRLALQRHEKHKHHVARYYCAICRLEFETPLEARRHRNQMKHKLKARPKASRSHLEKEIESMLREVLDEPTEPSGNPSKKTKIVSQKCSNCEEVFESPQDLARHRAKEHPGENHVCLSCGLSFQSTQAFGRHTRKCQPLASTSSSAPEDPKNTTFSCYQCPFRSQFKSDLIYHRFFHTRTGSISKHEIFKCPLCPKQFKKHSLRAHLRNHTNEKIFECPECPIKYARRHNLKDHIDTVHRKKEDLEATKLAKKKETAKEKAKYQCGTCGKILVKKYTLKIHELKHKEQLERNFKCHFANCSYAGLTQDNLKTHLVSHSQGSYKCDRENCAYVGKSEIHLKRHLKSAHPAEKDGGQWYSCDQCEFRARIKGHVRRHSLRHSGQTPHQCPHCDYKCSTIDNLRKHIVKTGKHPGKFLYECGKCSDQESVDIFKTNNYKDYQKHLDSHKVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00550565;
90% Identity: iTF_00615203; iTF_00504317;
80% Identity: -