Basic Information

Insect: Drosophila merina
Gene Symbol: -
Assembly: GCA_035047645.1
Location: JAWNPH010000059.1:17152481-17156575[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0045 0.41 11.4 0.7 3 23 240 261 238 261 0.95

2 10 0.011 1 10.1 4.6 2 23 402 424 402 424 0.91

3 10 0.0091 0.83 10.4 2.3 3 23 507 528 505 528 0.94

4 10 0.1 9.4 7.1 3.5 1 19 622 640 622 645 0.94

5 10 0.00018 0.016 15.8 0.2 2 23 760 782 759 782 0.96

6 10 0.0011 0.096 13.4 0.2 2 23 839 861 838 861 0.92

7 10 0.0088 0.8 10.5 3.6 2 23 915 937 914 937 0.96

8 10 0.086 7.9 7.4 4.2 2 23 951 973 950 973 0.92

9 10 0.0018 0.16 12.7 0.7 2 23 1036 1058 1036 1058 0.95

10 10 0.04 3.6 8.4 0.6 1 23 1154 1176 1154 1176 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0045	0.41	11.4	0.7	3	23	240	261	238	261	0.95
2	10	0.011	1	10.1	4.6	2	23	402	424	402	424	0.91
3	10	0.0091	0.83	10.4	2.3	3	23	507	528	505	528	0.94
4	10	0.1	9.4	7.1	3.5	1	19	622	640	622	645	0.94
5	10	0.00018	0.016	15.8	0.2	2	23	760	782	759	782	0.96
6	10	0.0011	0.096	13.4	0.2	2	23	839	861	838	861	0.92
7	10	0.0088	0.8	10.5	3.6	2	23	915	937	914	937	0.96
8	10	0.086	7.9	7.4	4.2	2	23	951	973	950	973	0.92
9	10	0.0018	0.16	12.7	0.7	2	23	1036	1058	1036	1058	0.95
10	10	0.04	3.6	8.4	0.6	1	23	1154	1176	1154	1176	0.99

Sequence Information

Coding Sequence: ATGGCTGCATCCATATATGCCACCCCACCGCCAGATCTGAGTAGCGAGGACACTGCTCTCTCGGACGTCTCAAACTCATCGACACTGAACACGAATCGCGGaaccaacaacagcagcagcaacagcaacaataacaataataataacaacaccAACAGTAACAGCACCCATGAAGCCCCAGGAGCAACAGCCACAACAGCTACAGGAGGAGAAGAAACGGGAGTGGGAGGACACACAGAGCACTTCGTCAAGGCGATGGAACTGGATCTGGAGCCAAAAGCAGCGGGAAGCGGCACAAACGATTCGGAAAGCCTGGAGGAGAAGGAGAGGGATTCCGAAATGGAAACGGAGAATAGCGCCGATATGGCCACCATGGCGGCAGCCATGCAGTTGCAACTCCTCGAGGCACTTAGCGATGCGGCCAAGAAGCGACGCAAACAACACAATCCCAGTCGCCTGGAGGCATTGAATCTAAGTGGCGAAGGCAACGAAGTGGAGAAGCCCAAAAGGCCGGTGGACTATGAGGAAAAGCTCTCCAAGATGTTCCTGCCCAAGTCCATAGAACAATTGAAGGAGACCTTTGAGTTGCTGCAGcaacaaaagcagcagcaggagatgGAGGAGGATGGGGAGCCACCAATCcaaccggaaacggaagccAACATATCATCGACAATGTCGCCCGGCAATCAGCGCGAAAATCCTTACCAAACTTTTTGCAAGCAGTGCGGCGAGAActttgaaaccgaattcaaactGAGTCTGCACATGTTACAGGATCATGGGGAGGAGCAGGGATCCGGGAGTCAGGATCCAGCTGATTTTCTGGCATCTATCAAAGTAAAGCTGGAGCGCTCGGAGAGTCCCAGTGCGCAGGATCAGCTGCAGTTGCAACTgcagcaacaactgcaacagcaacaccaccagcaacaacagcagcaccaccaccaccagcaacaTCAACTGTCCCAGGATATAACCAATGGCCATGGCAAGGATCTAGAGAACAGGGACCAGGAGAATGCCTGGTTCCAAGCCATGCATCATCCCCATGGTCCAGCCCTGCCGCCGGCCTTTCCCTTTCCCCCGGAGGCCGCCTTGGGCGTGGGTCCTGCCGGATACTTACCCCTCCTGGGCATGTCCGGCTTCCCCGGAGTGGATGGCTTGAATCGGCCGCCTTTGCGCATCTTCAACCCCGAGGCCTATTGCGAGCTGTGCAACAAGGAGTTCTGCAACAAGTACttcctcaaaacacacaaggCCAACAAGCACGGCATCTTCGATCCTGTGGGCGAATCCACCCCAGGATCCAACACTTCCAgccaccacaacaacaacaataccaACAGtacaaataacaacaatagCGGTGGCCCCAATCCAGGTCTGAGTTCCATGAGTCAGATGTTCCAAATGCAGAGGGAGGCTCAAGCCGTCAAACAGGATCTGGCCGGAGCAGGACCAGCTTCCCTGGTGCCTGGAGGAGCTACCCCAGGAACACCAGTGGCCTCGGTCCACTGCGACGTCTGCTCCAAACGCTTCACCAACGTTTTTGCCATGCGACGGCATCGGGCCAAGCAGCACGACACTTTGCCAACCAACCAGGACTCACCCACTTCGCAAAACCAATCCCGGCGAGCTAGTCCCACTGAGCAGACCATCAAGCAAGAAATGCCCCAAGAACCAGAGCAGGGAAAGCCCTATCAATTACCCGAGGGCTTCCGCGAAGATTTCAGTCTGGAGCAGGAGGAGCTGAGTTTTGTGCCACCGCCCAAGAAGCTACCGAGTCATCTACATCAGCAGGCGAAAGAGGCCAACTTGAATGCCGAAAAGCTGCGTCGCCTGGGGGTCCAGTTCCCGGAGTTCTACTGCGAACTGTGCCACCGGGAGTATGCCAACAGGTACTTCCTGCGCACCCACAAATGGAAGCGCCACGGAGTGTTTGTGCCGCCAGAGGAAGTGACACCTCAGGCTGGAGCCAAGGAGGAAGCCCAAATGAGCGCCTGGCCCTTTATGCCACTGAATCTAATGCTGGCTAAGGCGGCGGCTGCCTCTATGGATCAGCAGCAGGAAGGCGAGGCGGAAGCCGAACCCGAACCGGAGCCGGATACCGATCAGGATCAGCCAAGGAAGCGCATAAAGCTGGAGCAGGATACCACACCCACCGAAGGTTACGACGAAGAGAAGATTAACGGGTCGGTAATGGGTCTTCAGAACCTCCAGAAGCTGCAGTCTATGCTCCAGCAGCTGAACGATATCAACGGAAAGAGACCACTGCCATGTCATCTTTGCGGCCGGGAGCTGGAGAACCAGTATGCTTTGCGGGCTCATCTGATGACCGAACATGCCGGACAAATGCAGTTGCCAATGCAGATGCCCATTCCCATCCCTCTGCcagaccagcagcagcaacagcagcaggcaTCCCATCCCCTGTCGTCTCTTTATCATCAGGCTAATCCCCAGACCCCGCCCGGCACTGGAGCCAGGTCGTCGCCCGGTGGAGGAGATCTCCGTTGCCAGCAATGTGATCGGGATTTCGCCACCGCCCAGGAATTTAAGCAACATATCGCCGAGGTGCACATGGGTGGCCGCAGTGGCGGCCTCAACGGCAGTCCAACCCTGCGCGAGGGATTCTTCACCCCGGAAAGGCCCGTGATTCCCGGGAGAACGGGAGGCGGTGCCGATCCAGCTGCCCCGCCGGGCAACCGTCCGGCCTATACGATGACGCCCACCAGCAGCTATTGCGAGATCTGCAACAAGGAGCTGTGCAACAAGTACTTCATGAAGACCCACATGCAACGGATGCACGGCATCGAGATTGAGAACGGGGCCCAAATCGGTGGCGTAGTGTGCAACATTTGCAACAAGGAGCTGTGCAGCAAGTACTTCCTGCGGGTGCACAAGCACAACACCCACGGCATCATCGAGGAGGGCTCGCCCCTGCCTCAGCCCAGAGGACAAAACGGGGTCAAGCTTGAGGccgcggcggcggcagcagcagcagcggcagccgcCCAACAAAACCACGATCCGGAACAGTTGAACATCTCTCCCACGACAGTGGAGGGCGGCTCCTCCACCTCATCCAACTCCAATAACGAAGTGTGTCCCCTCTGTTCCCGGCAGTTCCGGAGCTTCAAGTGGCTGCGTTCGCATCTAATGAACGAGCACGGATCGGCGGGCGTGGAAAGGCTACGGGAACTGGAACCAACCGGACCCATCAATCGCAGCAAGCCCAATAGTCCAACACTCAAGATTCCCAACGGCAACGGGGCCAATCCGGGAGCTGCAGCAGGAGCTGGAAACCCCGCTCCTAATCTGGCCCAGGCCCTGCAGAACCTGAATGCCCAGCACCTTTTTGGGcaaatgcaacagcagcaaccacAGCTGCCCAAGATGCCGCCACTTCCTTTGCCTGGAATGTTTGGCGAGCAGGCCGCTGGCCGGTTCAAGGAATACCAGTGCTCCTTGTGTCCCTTCACCACGCCCTACTACGCCTTCCTGTTCATCCACGAGCGTTCCCACGCCCTACTCAACAATGGAGGCGAGAATATGGAAGTGCCACCTGTGGAGATGCCACCAGCACAAGCTCCCTCATCCAGAAGTCAGGGAAAGTCCCGCAGCAAGTCCAGCAAAGCTGCAGCTCCAGTGGCTGCACCACCAATTCCATCCGATGATCCAGAGGTATCCGTGGAGCCCACCAACCTGAGTACGGCCAAGGTAACGCCGCCATCTCCCCGACCATCCGTTGCCGCATCCCCTCCGTCTCCTCCCAAAGCCAGTTCCATTTCCCCAAGGATCAGTTCCCCGGCCAAGCCGCCATCCACTCCGAATGGCGTGGGCAGTGGTGGTCATCGATCCGCTGCCACCTCGCCCTTCGAAGGCTGCGGCGAATTGGCCAACGGCAGCGGAAAGCCGGCCAGTTACGCGCAACCGGAGCGCCCCGAGGAGTCCTACCAGATGCAGGCCTTCCACCTGCAACCCGCCGATGCCGACTCGGAACTCCAGTTTGCTCCGGCTCTGGTTTACTTGCCCGTCCGGATGCGGGCCTCCGAGTCCGCAACGCTCAGCTTCCGGCTCACACCTGCCTAA
Protein Sequence: MAASIYATPPPDLSSEDTALSDVSNSSTLNTNRGTNNSSSNSNNNNNNNNTNSNSTHEAPGATATTATGGEETGVGGHTEHFVKAMELDLEPKAAGSGTNDSESLEEKERDSEMETENSADMATMAAAMQLQLLEALSDAAKKRRKQHNPSRLEALNLSGEGNEVEKPKRPVDYEEKLSKMFLPKSIEQLKETFELLQQQKQQQEMEEDGEPPIQPETEANISSTMSPGNQRENPYQTFCKQCGENFETEFKLSLHMLQDHGEEQGSGSQDPADFLASIKVKLERSESPSAQDQLQLQLQQQLQQQHHQQQQQHHHHQQHQLSQDITNGHGKDLENRDQENAWFQAMHHPHGPALPPAFPFPPEAALGVGPAGYLPLLGMSGFPGVDGLNRPPLRIFNPEAYCELCNKEFCNKYFLKTHKANKHGIFDPVGESTPGSNTSSHHNNNNTNSTNNNNSGGPNPGLSSMSQMFQMQREAQAVKQDLAGAGPASLVPGGATPGTPVASVHCDVCSKRFTNVFAMRRHRAKQHDTLPTNQDSPTSQNQSRRASPTEQTIKQEMPQEPEQGKPYQLPEGFREDFSLEQEELSFVPPPKKLPSHLHQQAKEANLNAEKLRRLGVQFPEFYCELCHREYANRYFLRTHKWKRHGVFVPPEEVTPQAGAKEEAQMSAWPFMPLNLMLAKAAAASMDQQQEGEAEAEPEPEPDTDQDQPRKRIKLEQDTTPTEGYDEEKINGSVMGLQNLQKLQSMLQQLNDINGKRPLPCHLCGRELENQYALRAHLMTEHAGQMQLPMQMPIPIPLPDQQQQQQQASHPLSSLYHQANPQTPPGTGARSSPGGGDLRCQQCDRDFATAQEFKQHIAEVHMGGRSGGLNGSPTLREGFFTPERPVIPGRTGGGADPAAPPGNRPAYTMTPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLRVHKHNTHGIIEEGSPLPQPRGQNGVKLEAAAAAAAAAAAAQQNHDPEQLNISPTTVEGGSSTSSNSNNEVCPLCSRQFRSFKWLRSHLMNEHGSAGVERLRELEPTGPINRSKPNSPTLKIPNGNGANPGAAAGAGNPAPNLAQALQNLNAQHLFGQMQQQQPQLPKMPPLPLPGMFGEQAAGRFKEYQCSLCPFTTPYYAFLFIHERSHALLNNGGENMEVPPVEMPPAQAPSSRSQGKSRSKSSKAAAPVAAPPIPSDDPEVSVEPTNLSTAKVTPPSPRPSVAASPPSPPKASSISPRISSPAKPPSTPNGVGSGGHRSAATSPFEGCGELANGSGKPASYAQPERPEESYQMQAFHLQPADADSELQFAPALVYLPVRMRASESATLSFRLTPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481822;
90% Identity: iTF_00615151;
80% Identity: -