Basic Information

Insect: Drosophila merina
Gene Symbol: Trerf1
Assembly: GCA_035047645.1
Location: JAWNPH010000002.1:20955823-20968526[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.011 1 10.2 1.1 2 23 342 363 341 363 0.97

2 6 3.7e-06 0.00034 21.1 1.3 1 23 369 391 369 391 0.98

3 6 0.00037 0.034 14.8 2.5 1 23 397 421 397 422 0.94

4 6 0.00062 0.056 14.1 0.8 2 23 695 716 694 716 0.97

5 6 0.0017 0.15 12.8 0.1 1 23 1840 1864 1840 1864 0.97

6 6 8.3e-05 0.0075 16.9 0.8 1 23 2002 2024 2002 2024 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.011	1	10.2	1.1	2	23	342	363	341	363	0.97
2	6	3.7e-06	0.00034	21.1	1.3	1	23	369	391	369	391	0.98
3	6	0.00037	0.034	14.8	2.5	1	23	397	421	397	422	0.94
4	6	0.00062	0.056	14.1	0.8	2	23	695	716	694	716	0.97
5	6	0.0017	0.15	12.8	0.1	1	23	1840	1864	1840	1864	0.97
6	6	8.3e-05	0.0075	16.9	0.8	1	23	2002	2024	2002	2024	0.98

Sequence Information

Coding Sequence: ATGGCTGCCATAAATACGGTACCCAAGAGCATACACCTGCCACTGACAAGTCTCAGCAGCGCGCCGCGCGTGCTGATGTGCAGCGCCTCCGTGGGCACCGAGGGATCCGTAACTCTGCAACTAAGAGATGCAaacgcagcaacagcagcagcagcagcaacctcAGTCGCCGTcccagcatcagcagcaacatcaatcGCCACATCAACGTCAGCGTCAGCGTCAGCAACAAATGGCGTTGCAACGCTTGCCACCTCTGCGGCAAATGCGTCAGCGTCGACGCTAGAGAATGCGCTGACAATTGGCTATCCGGATCCGGAAATGTTGGCAGATGTCTTGGGCACCATTCAGACAGCCTCTcttaaaaacaacagcaacagtagCAACAACTCAATCCCAACAGCAACCTCAAGCAATAGTTCAAGCAAGTCGACGAGCAGCAATCAATTGGGTAACTCCAATAAAATAACTATAACTAGGCGAAGCGTTCAATCGGTGAGCACATCCACCAACACGAGCATCAgtagcagcagtagcagcaacagcatcagcagcaatACCAGCAGCGGCAAGACAAACACCAGCTATATAAAAAACTGCTTGAtacgcagcagcagctgcagcaacaCGGTCACAAATGTCACGACGCTGGCGCAGATTAtgagcaacagcagcaccagcagcgcGGCAAGTTTACTCAATcagcacaacaacaacagcaactgcagcaacagcagcaacttcAGTACCGCCTCCTCCGTGGGCAGCAGCATCAGTatcggcagcaacagcagcagcaacagcaacagcaacagtaacgacagcaacagcagcagcggcggcatcCACAGTTTAAGCTTCAAGGGCACCGGTAGACATGTTCCTGGATCAGCGAACGGAGTGAGCTCTTCGGTTGGAGCATCCTGCCACAGTGGTGTCACCGGGGTCAGTGGGATCATCAGTGTCGAAGCGCCGCGCAAGAACCGACCCAAATTATCCTCCCCGACGCGACACGGACCGCAACAGTGCCAGATTTGTTGCAAGATCTTTGGAAATGCCTCGGCGCTGGCCAAGCACAAACTGACGCACAGCGACGAACGGAAATACATCTGTGCGCTCTGCTCGAAGGCATTCAAGCGGCAAGATCACTTAAACGGACACATGATGACTCATCGGAACAAGAAGCCTTACGAATGTAAGGCGGATGGCTGTGGGAAGTCCTACTGCGACGCCCGATCTCTTCGGCGGCACTCAGAGAACCACCACGCAGGTGGTGTGGCCACCCCCACCACCAGCCAGTCCCTGTCGCCGACTGCCAGCTCCAGCGGagcgagcagcagcagcagtagcagcagcagcggcagtgtCAGCGGTAGCGGACTAGGCGTGGCCACCAATACGCTCAGCCTCTCGCCGGCAACAGCCAGCGGGGATGCCAGCTCTCCGGACGGAGCCACCTGCATAAGAACCTACATTTCCACGGGAAACTCGGTGGTAGATGCGGCCACCGGGATAGCTCTGTCGGATGAGCAGATCAAGGCCATGAACCTGCCGATCAAGACGGGCGTCACCCTGCTCTCGCCCACCACCTCGACTTCCTCGAACGCCTCCTCCACGGCCAGCAGCTCCGGCTCTTCGCTGTCCTCCGCCTCCGTGGGGACAGCCTCATCAGCGGCTAGCCAGAGTGCGGTGATAGCCACCACCAGCTCCCCCACCATAACGCTTAGCGACGGGGTGAGCCTCGAAGGCGAGGGCCTGACCCGGGAGCAGTTGGATCTCATCAGCAAAATCATGCAGCAGACAAAGCAGACGAGTGCACAGGTCACCGTCTCATCGCCCACCAGTGTCAGCTCCTACAAGATCAACACCAATTCGGCGTCAACACAGTCGAGACCGCGCACCTGGAACATGCAATTGCTCAACAATTCGCAGAATGTGACTGTCACCGTTGAGGATAATACCGACATGATTGCTCCCTCTTCCAACTCCCCCGTAGAGAtcaaggaggaggagctgaaCCAACAGATTGTGGCCGCCATCAATCCCCACCTGCTCAACATTGTAAAGCTCGACAAGCCGGTCGAGTGCAATCTCTGTCACCGTAAGTTCAAAAACATACCCGCCCTCAATGGGCATATGCGCCTCCACGGCGGTTACTTCAAAAAGGATCCGGAAACCAGGCGCAGCGAGAAGAAGGATTCAAGTGGACCGCCCCTGCAGACGGCCAGTATTGGTGTCCGTGCTCTGATCGAGGAGAAGATTATAAGCAAACGGAAGGATATCACAAAGGGCTCCTTTGTGGTTCCTGCCCCACCGCACAGTAGTGGCACCACCACTCCTCTGAGGCGTTCCATTAGCGACCTGGAGAGCTTCCTCAATCCCAAGAGTAGCTCGAGTGGACACACCCAGACGTTGGCAACCAGCACGGGAACCACCACAGCCGTACTCCCGGCAGCCACCACCATCAAGAGCAGCAACGGACTTAGTATCCAGCAGATTGGACTGCCGCAGAGCATCGAGATCTTCAGCGGGGGCCAGAAGCAGGCCAAGACCCTGAATTTGGGCAGTGGCACCAATACCATCACCATTACCACCAATAACGtgcccaccaccaccacaatgAGTGCCCTGACTGCCCTGAAGGCCGGCGGCACAATCAGCGGCATTTCCACAGCCACCAACACAGATCCTAAGGACTCCACTCTCATAGAGCTCCTAAAGCGTGGCACTCGCATTGCGGTGACCTCGAAGAAAACCCAGTCGCAAACCCAAACCGGGTCCAGCGTCTTAATGACCTCCAGCGGCACAGCAACGAGCGCCATGGGTGGGGTAACCGAATTGACCACCATTGGCAGCAACAGTCTGCAGACGGTGGGACGACAGATTATAACAAACAACAACCGTACGGTGATCATACCCTCCGATGTCCAAGTGGTGTCCACCAAGACCAAGCTGAGCACCTTGAGCAGCCTGGTTaagagcagcagcaccaccaccaccacagtCTCGAACAGCGGCTCCAACACCACCTGCTCCTCTGGGAACATTTCCCTGGCCGATGGTACGCCGCTCTCGCTGACCATTACTCCCAATCAGGAGATGTCCGGTGGCGGCTCTTCATCGGGTAGTGTTATCACAAGCGGCGGGGGTGGAGTTTACACAGTCACCTACACCAGCGATGGCACCGATCTCTTCGACGATGCCGAAGTCTACAACGTTTCCGATACGGAGATGCTGCTGCAGACAGTGGACTCCATGGAGCTGCTAAATGACGACGAGGACGACACACAGATCAAGAGCGAACATTCCGAAGACTTTGCCCTGCTGAGCGATGCTGGCGACAGTGTGCACACCCAGCTGGTTAAGCTGGACACGGAGCATATAGCCGGATCGGGTAACATTGGAAACAGCAACACCGCCACTAACAACGCCACCACCACACCGCTGCCCACCTTCCAACAATTCCATTCCAAGGAACTGATTATGCAGAACAGTTCGCAGATCCAGGCAATAGCCAGCATGCGCAGCAGTAGCGGTGTCCTAGCCTCGCCGCTCCACTCCCCACTGGCCTACCCTACGCCGCCCTCAAGCCACGAGAATATGGCCCAGAGTTCCCCATTCATCGAGGATGCAGCTGCCCAGTTTGTGGATGCCAGCAACACTTTCTTTGGCGACAAGACCGACTTCTCGCACATCTACTTCAAGACCGACGATGGCCAGGCTACCATCGAGCAGCTGGATGATCAGGACAATGAGAAGATCCTGAAACTGAAGTCTGTGCTTGAAGAGAGTAGCTTTGACCCTTCCATCAAGGTGGAGGACCTACTGAATGGCACCGATGACGACACCGAGTGTGATCTGCGGGAGTTTGCCGAGACGAATCTTTCGTTTCTGGATGAGGACCAAGAGTTCCTCAATGACTCCCGCAACGCGACTTCCCCACTTTCAGAGTCGTTCTTCACCAGCGGCATTGGTTCGGCTGAGGATGTGAAACAGGTCCTGCGAGAAGTCCTGCCGGACGAAAATATGCAGTTGCAGTTAAGCAGCGAGCAACAGGGCGAGAACATAATCGATCTCTACTATCTTCCTGGTCTGGGTTTGCAATCTCAGATGATGCCAAATTCGGAGGATCCCTTGTTGTCCTCTTCTCCTAGGGAATTTGGCCAGCAAAGACAGCAAGTGAgcttgcaacaacaacagcaacagcaacagcaacaacaccagcaacagcaccagCCCCTGGAGCAGCAACTTCAGAACAGTAATAACCTTTacgagcagcaacagcaggagcAACATCAGCCATCACAGCAGGAGACccagcagccacagcagcagcaacttcaGCAGCAACAATTGATGCTGCCACAGCAACAGCTGAATCAATCCGAAACTCTCCCTGTGGCCAGCAATCAGCAGGCCGATTTTATGTTGCCCCTAGTGGGAGGTCATGGCTTTACGTCCCTGCCTAACCAAAACCAATTCCTGGACAATAGCCAGGGGGGCGGAATGGGACTGCAGCCCCTAAATAGCCTGCTTCAGCCCCTGCTCTTTAGCGCCAGTGGAGCTGGTTCCAATGGAAATCTGGTTGCGGGCAACGATACCCATCTCCCCGCCGATTGCCAAATGAATACAAATCAGACAACGCAGCTCGATGGAAGTCTGTTGTTCGCCTGCGGCCCGGCGGTAACAACGGGCAACAAGCCCCTGCTCCCGGCCATCCCGACTCAAGTGGCCAATTTGCAACCGCTGTCGAACCAAACCAATTCCATTCTGAAACGCCGACTGCGTTCGAACGCGCCTCAGGAAACGCACAAGTTCTCCAAGTTCCATACTCTATCGCCGCATCGCTCCAAGCTGCGCAAACCCTCCCGAACCCACTACACTCCCGCTCCCATCCTGAATCCGGACCGCAAGGGAACCGGGCTCTACTGCAATGTACGGAAGCAGTTGGGTCAAGGGCTGTTCGATGCCTTCGATGACGACTTCGGGGACCCGGTGGGCCTGGTCGACTTTTCCGACGAATCAAAGGTCAACCTGGGCTCCACCTACCAGGCGCAGATTCCCAGCTGCAGGTCACAGGAGGAGGCGGCACGAGAGGATGTGGGAGCCGAGATGATGTGGAACCCCGAGGTGCAGGAGGACGAGAAGATCCTGATGCGCTACATAGATCTCAGCAAGTCGTCGGCCGTGCCATTGGGCAGTCATTCCGAGGAGGTGGCCCTCCACACGCTGCTCAAGGCCCGCGGGAACTCAGCGGCGGCGGTATTGAATCTGCTGCAGACCCAGTCCGGGGCCTTCCAGATGAAATGGAGCTCTCACGAGCTGGAGCAGTTCCTGCGAGGGCTGGAGAAGCATGGCAAGGACTTCGGCAAGATTGCGAACACGCTCCTGACGAAATCCTCCGGTGAGTGCGTGCAGATGTATTACTTCTGGAAAAAGCTGTGTGTAGACTACAAGGTGTCGCACCTCAAGATGGAACCCGTGGCCGTGGTAACGCCACCCGTGGAGAAACCCTATGTGTGCGAGATCCCCGACTGCTCGGCGAGCTTCAGTTCAAAAGCGGCACTGCACGGCCATGTCCGCATACACGCTTACGGCCGTAgtgccagcagcaacaacaacaacaacaatggcagcatcagcaacaacagcagcagcagcaacatgagtAACCAGCATGCAGCGCCGAATAGTGCCAGCAATATAAGCAGCAACAGCGGATACGCATGTGCAACACTCGCAAGTGTCAACAGTGGCAATAACCTCAACAACAATGCCTCATcatctgcagcagcagcaggtgctGCAACTCATGCCATGGGCAGCAGTAGCAACTGCAATCTCAATTCAAATAGCAACgccacaacagcaacatcgacCTCAATCTTGGCCACTTCCAAGCTGGAATCGGGTATTGGTAACAGCAACAttaacggcaacggcaacggcaatggCAACGGCAACACCACCAATGTTGTTCCGAATGCCAAGGAGGGCGAATTCCCCTGCAAGGTGTGCGGCAAAGTCTTCAATAAGGTGAAGAGTCGTAGTGCTCACATGAAAACCCATCGGGTCCAGGAACCGGACCAGTCTGCCAaacaccaccagcagcagcaacagcaacaccaggCCAATGTTTCCACAGGATCCGTACTGGCCACTATCGCCTCGACCTCAACAATTGCATCCGCTACATAG
Protein Sequence: MAAINTVPKSIHLPLTSLSSAPRVLMCSASVGTEGSVTLQLRDANAATAAAAATSVAVPASAATSIATSTSASASATNGVATLATSAANASASTLENALTIGYPDPEMLADVLGTIQTASLKNNSNSSNNSIPTATSSNSSSKSTSSNQLGNSNKITITRRSVQSVSTSTNTSISSSSSSNSISSNTSSGKTNTSYIKNCLIRSSSCSNTVTNVTTLAQIMSNSSTSSAASLLNQHNNNSNCSNSSNFSTASSVGSSISIGSNSSSNSNSNSNDSNSSSGGIHSLSFKGTGRHVPGSANGVSSSVGASCHSGVTGVSGIISVEAPRKNRPKLSSPTRHGPQQCQICCKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKADGCGKSYCDARSLRRHSENHHAGGVATPTTSQSLSPTASSSGASSSSSSSSSGSVSGSGLGVATNTLSLSPATASGDASSPDGATCIRTYISTGNSVVDAATGIALSDEQIKAMNLPIKTGVTLLSPTTSTSSNASSTASSSGSSLSSASVGTASSAASQSAVIATTSSPTITLSDGVSLEGEGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSYKINTNSASTQSRPRTWNMQLLNNSQNVTVTVEDNTDMIAPSSNSPVEIKEEELNQQIVAAINPHLLNIVKLDKPVECNLCHRKFKNIPALNGHMRLHGGYFKKDPETRRSEKKDSSGPPLQTASIGVRALIEEKIISKRKDITKGSFVVPAPPHSSGTTTPLRRSISDLESFLNPKSSSSGHTQTLATSTGTTTAVLPAATTIKSSNGLSIQQIGLPQSIEIFSGGQKQAKTLNLGSGTNTITITTNNVPTTTTMSALTALKAGGTISGISTATNTDPKDSTLIELLKRGTRIAVTSKKTQSQTQTGSSVLMTSSGTATSAMGGVTELTTIGSNSLQTVGRQIITNNNRTVIIPSDVQVVSTKTKLSTLSSLVKSSSTTTTTVSNSGSNTTCSSGNISLADGTPLSLTITPNQEMSGGGSSSGSVITSGGGGVYTVTYTSDGTDLFDDAEVYNVSDTEMLLQTVDSMELLNDDEDDTQIKSEHSEDFALLSDAGDSVHTQLVKLDTEHIAGSGNIGNSNTATNNATTTPLPTFQQFHSKELIMQNSSQIQAIASMRSSSGVLASPLHSPLAYPTPPSSHENMAQSSPFIEDAAAQFVDASNTFFGDKTDFSHIYFKTDDGQATIEQLDDQDNEKILKLKSVLEESSFDPSIKVEDLLNGTDDDTECDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPDENMQLQLSSEQQGENIIDLYYLPGLGLQSQMMPNSEDPLLSSSPREFGQQRQQVSLQQQQQQQQQQHQQQHQPLEQQLQNSNNLYEQQQQEQHQPSQQETQQPQQQQLQQQQLMLPQQQLNQSETLPVASNQQADFMLPLVGGHGFTSLPNQNQFLDNSQGGGMGLQPLNSLLQPLLFSASGAGSNGNLVAGNDTHLPADCQMNTNQTTQLDGSLLFACGPAVTTGNKPLLPAIPTQVANLQPLSNQTNSILKRRLRSNAPQETHKFSKFHTLSPHRSKLRKPSRTHYTPAPILNPDRKGTGLYCNVRKQLGQGLFDAFDDDFGDPVGLVDFSDESKVNLGSTYQAQIPSCRSQEEAAREDVGAEMMWNPEVQEDEKILMRYIDLSKSSAVPLGSHSEEVALHTLLKARGNSAAAVLNLLQTQSGAFQMKWSSHELEQFLRGLEKHGKDFGKIANTLLTKSSGECVQMYYFWKKLCVDYKVSHLKMEPVAVVTPPVEKPYVCEIPDCSASFSSKAALHGHVRIHAYGRSASSNNNNNNGSISNNSSSSNMSNQHAAPNSASNISSNSGYACATLASVNSGNNLNNNASSSAAAAGAATHAMGSSSNCNLNSNSNATTATSTSILATSKLESGIGNSNINGNGNGNGNGNTTNVVPNAKEGEFPCKVCGKVFNKVKSRSAHMKTHRVQEPDQSAKHHQQQQQQHQANVSTGSVLATIASTSTIASAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00477570;
90% Identity: iTF_00481772;
80% Identity: iTF_00545906;