Basic Information

Insect: Drosophila merina
Gene Symbol: wdn
Assembly: GCA_035047645.1
Location: JAWNPH010000002.1:19397402-19400194[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00017 0.015 15.9 0.3 1 23 313 335 313 335 0.99

2 7 0.049 4.5 8.1 1.8 2 23 346 366 345 366 0.93

3 7 5.3e-07 4.9e-05 23.8 1.1 1 23 372 394 372 394 0.99

4 7 4.9e-06 0.00045 20.7 4.2 1 23 400 422 400 422 0.98

5 7 0.00018 0.016 15.8 3.0 1 23 428 450 428 450 0.97

6 7 4.3e-06 0.00039 20.9 0.8 1 23 456 478 456 478 0.96

7 7 8e-05 0.0073 16.9 2.3 1 23 484 507 484 507 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00017	0.015	15.9	0.3	1	23	313	335	313	335	0.99
2	7	0.049	4.5	8.1	1.8	2	23	346	366	345	366	0.93
3	7	5.3e-07	4.9e-05	23.8	1.1	1	23	372	394	372	394	0.99
4	7	4.9e-06	0.00045	20.7	4.2	1	23	400	422	400	422	0.98
5	7	0.00018	0.016	15.8	3.0	1	23	428	450	428	450	0.97
6	7	4.3e-06	0.00039	20.9	0.8	1	23	456	478	456	478	0.96
7	7	8e-05	0.0073	16.9	2.3	1	23	484	507	484	507	0.98

Sequence Information

Coding Sequence: ATGGAGTGCAAAGGCAAGGGCAAGAGAATGAAGAAGGAGGCGCCAAGCAAGAAGTTGCCGCCTAAAATCTACGGCGATGGTGGAACACCAACAAAAGCGGCCCACGACGAAATCCTCAGCTCCCTGCTGCGGATCAATAACTTCGACTCGATATCGAGCATCAAGGATGAGTCGTTGGACATTGATCTGTCCGCCTGCGTGACCATCAGCTCCGCCAGTCTGGTCAACGGAAACAGCCTCTCATCGACGGACTTTTGGCGCGTGCTCGACGAAAGCGCGCAGAACAACACAGAACTGAATCTATTGGCGGACGTGTGCCGCGATGACCTGGCGGGTTccagctctggctctggctccggTCTCGGCCATAGCTCCCTCGTACCCGTACCCAGTACCAGTGAACACCATTCTAGCTCTGAATTTAACGTCACGTTCCTGCGCCCGGAACCACCGAACGCGTTTACCAATTCGCCGTTCAAGAAAACTTCCAGCGGAGCCCCCTCAACCGTCAAGCTCTCGCCCGAGCAGCTGCAGatccagcagcaacaactacTAGTTCAACCTCCCATCCAGCGCAAACCCAAGTTGCCAGCGACGACAGCGTTGCGTCTAAAAGTCTTCAAGGAAGAGCCACTCGAAGAGAAGCACATTCAAATGGGTCAAAGTCCCGCGCCAGTGGTCACCAAGGTGGAGATGAGCGAGGCCGAGTTCATGCCTCCTTCGTTTACCATTTTTCAGCAGCCAAAGCCAACATCCACAACCTTTGCAGACACGGATGCAGCTAGTATGCCGCCTCCTGTCATGGAGGTCCACGAAAAACCTGTGGAGGTAGACCCGGCGCCGTTGCATAAGTGCTTGGACTGCAACGGGTTACTGCTGGAGACGCCCGAGGAGTTGGCCAAGCATGAGTCGGCCGCCCATCGGCTGCGTCTCATCTACCGCTGCGGTGAGTGTCAGCGGGAATTTGAGATTTTAGCCGGGCTAAAGAAGCACCTTAAGACGCACCGCACGGATGGCCGCAAAGATACGTGGAAGAAATGTCCTGACTGTGGCAAGTGCCTCAAATTAGGAAGTATGTGGATGCACCGAAAGATCCACAGCGACAACAAGAAATACCAGTGTGACATCTGCGGCCAGAAGTTTGTCCAAAAGATTAACCTTACGCACCATGCCCGCATCCACTCCTCGGAGAAGCCCTTCGAATGCCCAGAGTGTCAGAAAAGATTCCAAGAGCGGTCCCATCTACAGCGCCACCAAAAGTACCATGCCCAGACGCGTTCCTACCGCTGTGAGAAGTGCGGCAAGATGTATAAAACGGAGCGCTGTCTCAAGGTTCACAATTTGGTGCATCTGGAGCAGCGCCCATTTGCCTGCACCGTGTGTGATAAGAGCTTTATCAGCAATTCCAAGCTAAAACAGCACTCGAATATACACACGGGCATGCGACCATTTAAATGCAACTACTGTCCGCGAGACTTTACCAATTTCCCTAACTGGCTTAAACACACGAGACGTCGTCATAAGGTTGACCATAAGACGGGCGAACACCTTGAGAACATTCCCTCTTACTGCTCTAAGAAGTCCACCACCAACAAGGCCCAGaaagcggcagcagcagcggcagctgcagcggcggcggctgcgGCAACCTCTGCTAATACCGATAATTCTGTCGCAACGCATGATTTGAAAATTAAGTCCGATCCTTCTCCTATATCCACGCCGGTCCCCGCGAAACAGGTGCGCAAAAAAAAGCAGCCCCAGCAGGCCACTCTTGCCGCTTTAGGAATCACTCTGCCAGCCGGAACAGCATTGCAACAGGTTCACCCTGTGCCGCCAGCTACGCAGCAATCGGAACTCTCTTCTGTTCTGGTGGCGCTTCCCCCACCGCCTCCAAAGCAGGCCAAGACTAAGCGGGAGCGAAAGCAACTGACCCCAAAGCAACTACAGCAAAAACCACAACTTCAGATAACaaatcagcaacagcaacaacccGCAAGTGCTCCCCTGAGTAGCATTTCGCAGATCAAGAAGGAGCCGGTGCAGAATCAGGGCCCGTTCTTGGACCTACATGGTCTTAGCCTGACTTCCGCCGAGGATCTGATTATGGAGCAGGCACTGGAAATGGAAGAATGTGGCCTTTACGATGCACCCAATGCTAACACCGACATGGGGACGTCGGATAACGCCATCTCCGAATCTGCTGCTGCCCTGCACTTTCAGATAAAAAACGAATTGCCAGACGAACTTTTGCCAGATGAAGATTTCATGCCTTGTAAGCCAAGTGATCGCCTTGCCTGCCCATCACTTGAGTCCTCGCCGTTTTCTTCGCCAGCCTCTATGGAACTGACCGCAGTATCCGCTTCTGTACCCAGTAATGTACCAAGCGCTTCGCAAGCGATGCCGGCGCGTTCGGGGAACTATTATCTGCCCGCCTTCACGCTGAACGCGCAAGGAAAGTTGAGCCGCATGGTTAATACAGTGCAATCCGTACCCACAGGAGCCCCATCTGCAAGCTCTGCGATGCCAGTAGTTAATGTGCCACTGCTGGTACGCTCCAACCAGATGCTGCCTTCAGTGGACACACTGCTATTTACCACCCAAACAGGTGGCAATCGATTTTTCGCGGGAAAATCAGCCCCGGCACCTACGCCGCATCTGACATGA
Protein Sequence: MECKGKGKRMKKEAPSKKLPPKIYGDGGTPTKAAHDEILSSLLRINNFDSISSIKDESLDIDLSACVTISSASLVNGNSLSSTDFWRVLDESAQNNTELNLLADVCRDDLAGSSSGSGSGLGHSSLVPVPSTSEHHSSSEFNVTFLRPEPPNAFTNSPFKKTSSGAPSTVKLSPEQLQIQQQQLLVQPPIQRKPKLPATTALRLKVFKEEPLEEKHIQMGQSPAPVVTKVEMSEAEFMPPSFTIFQQPKPTSTTFADTDAASMPPPVMEVHEKPVEVDPAPLHKCLDCNGLLLETPEELAKHESAAHRLRLIYRCGECQREFEILAGLKKHLKTHRTDGRKDTWKKCPDCGKCLKLGSMWMHRKIHSDNKKYQCDICGQKFVQKINLTHHARIHSSEKPFECPECQKRFQERSHLQRHQKYHAQTRSYRCEKCGKMYKTERCLKVHNLVHLEQRPFACTVCDKSFISNSKLKQHSNIHTGMRPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLENIPSYCSKKSTTNKAQKAAAAAAAAAAAAAATSANTDNSVATHDLKIKSDPSPISTPVPAKQVRKKKQPQQATLAALGITLPAGTALQQVHPVPPATQQSELSSVLVALPPPPPKQAKTKRERKQLTPKQLQQKPQLQITNQQQQQPASAPLSSISQIKKEPVQNQGPFLDLHGLSLTSAEDLIMEQALEMEECGLYDAPNANTDMGTSDNAISESAAALHFQIKNELPDELLPDEDFMPCKPSDRLACPSLESSPFSSPASMELTAVSASVPSNVPSASQAMPARSGNYYLPAFTLNAQGKLSRMVNTVQSVPTGAPSASSAMPVVNVPLLVRSNQMLPSVDTLLFTTQTGGNRFFAGKSAPAPTPHLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615106;
90% Identity: iTF_00504192;
80% Identity: -