Basic Information

Insect: Drosophila merina
Gene Symbol: salm
Assembly: GCA_035047645.1
Location: JAWNPH010000055.1:19262328-19270702[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 3.9e-06 0.00036 21.0 0.9 1 23 460 482 460 482 0.98

2 7 7.7e-06 0.0007 20.1 2.1 1 23 488 510 488 510 0.98

3 7 0.013 1.2 9.9 1.5 2 23 848 869 847 869 0.98

4 7 5.5e-08 5e-06 26.9 0.5 1 23 875 897 875 897 0.98

5 7 0.00017 0.015 15.9 2.3 1 23 907 929 907 929 0.98

6 7 0.022 2 9.2 2.9 2 23 1311 1332 1310 1332 0.97

7 7 2.2e-08 2e-06 28.1 1.3 1 23 1338 1360 1338 1360 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	3.9e-06	0.00036	21.0	0.9	1	23	460	482	460	482	0.98
2	7	7.7e-06	0.0007	20.1	2.1	1	23	488	510	488	510	0.98
3	7	0.013	1.2	9.9	1.5	2	23	848	869	847	869	0.98
4	7	5.5e-08	5e-06	26.9	0.5	1	23	875	897	875	897	0.98
5	7	0.00017	0.015	15.9	2.3	1	23	907	929	907	929	0.98
6	7	0.022	2	9.2	2.9	2	23	1311	1332	1310	1332	0.97
7	7	2.2e-08	2e-06	28.1	1.3	1	23	1338	1360	1338	1360	0.99

Sequence Information

Coding Sequence: ATGAAAAATCACCTGTCCAACGTTTTGTGTGCGATGCGTAGTGACTTCAAGGATAATCACCAGGAGACCATCAATAAAATGATACAATTTGGCACAGTGAAATATGGCATTGTCAAACAGCTGAAGGATCGCGCTCGCAGCGCCGACAAAGACACAGGCAGCGATCAAGAGGAGAATGGTGGCTGCTCGCCATTGACCACGGCCACCACCACGGCCAGTCCCAGCCGGAGTCCCGAGCCGGAAGATCAGGATCACCAcgatcaggatcaggatcaCCAGGTATCCTCTCCCCTCACAGAACAGGTAGAAAAGCCCTTCGAAACGTTgcaacagaaaacagaaatcgAACCCATAGAGGATAACAATAATAAGGTAGAAATGACCAAACCAAATTCTGAAGATCGCGATCGGGATCGGGAGCGAGAGCCCAATGCCAGTGGCTCCATGCCCAGTTCCCCGGTGGCCGAGGCCAGTGCCGAGGAGGCGGCCACGGAGAGAGCTCCGGAAAAGGAGAAGGACATCGAAGTAGAtgtggagatggagatggcgGATGAGCCAAGAAGTGTCCTACCCGCCACGGAGATGGGAAGTCTGCCCGGAGCAGCCGGGGCTCCCGTGACCCTCGAGGCAATCCAGAACATGCAGATGGCCATTGCCCAGTTTGCGGCCAAGACCATTGCCAACGGATCCACCGGAGCAGACAATGAGGCTGCCATGAAGCAGCTGGCCTTCCTCCAGCAGACCCTCTTCaatctgcagcagcagcagctcttCCAGATTCAGCTCATCCAGCAGCTCCAGTCCCAGCTGGCCCTCAACCAGGCCAAGCAATCGGAGGACGATCAGGAGGAGGAGCCAGAGCAGGACGTcgagcaggaccaggagctgGAGACGGACACctacgaggaggaggagcgtATCGCGGACATGGAGCTGCGTCAGAAGGCCGAGGCCAGGATGGCGGAGGCCAAGGCCCGCCAGCATCTGATCAATGCCGGTGTGCCGCTGCGAGAAAGCTCGGGTTCCCCGGCGGAAGCCCTGAAGAGGAGGCGGGAGCACGACCAGGAGTCGCAGCCAAGCCGCCGACTGAGCTCCGAAGCCTGCATAAAGAGGGAGAACCACTCCCAGCAGGATGCCCTCGCCAAGCTGAAGGATCTCGAAAACACTCCCCTGCCGTTCGGTTCGGACTTGGCCTCCAGCATCATCACCCACCATGATGACCTGCCGGAGCCCAACTCCCTGGAAATGCTGCAGAAACGCGCCCAGGAGGTCCTGGACTCCGCATCGCAGGGCATCCTGGCCAATAACATGGCCGATGACTTTGCCTTCGGAGACAAGTCCGGGGACGGAAAGGGCCGCAACGAGCCGTTCTTCAAGCACCGCTGCCGGTACTGCGGGAAGGTCTTCGGCTCCGACTCTGCCCTCCAGATCCACATCCGATCTCACACCGGAGAGCGGCCCTTCAAGTGCAATGTGTGCGGGAGTCGCTTCACCACCAAGGGCAACCTGAAGGTCCACTTCCAGCGACATGCTCAGAAGTTTCCCCACGTGCCGATGAACGCCACTCCCATCCCGGAGCACATGGACAAGTTCCACCCGCCTCTGCTGGACCAGATGTCGCCCACGGACAGCTCCCCCACCCATTCGCCGGCGCCACAGTCCGGTCCGTTTGGTTCGGCCTTCCCTGGACTCCAGAATCTCTATCGTCCGCCCATGGAGATCCTGAAGAGCTTGGGCGCCGGTGCCCCGCATCCCTTCTTCCCTCAGGACTTGCCCACGGATCTCCGCAAACCCTCGCCGCGCctccaggaggaggaggaggcgatGGAAGCTGTTCCCGTAAAAAGGGAGATCGTTGAGGAGGAGAAGAATgcgcatcagcagcagcaatgcGAGCAGGAAGAGCGGGCATTGAGCCAAAGAGAAGAGGAGCAGGATAACCGCAACTCCTCGCCGGAGCCAGAGCCTCTGCCGCTGGAGGTGCGCATCAAGGAGGAGCGCGTGGAGGATGAGCCTGAACAGGAGCCGGTCCAGAAGGAGGAGCGAAGGAGCCCGTCCCCATTGCATCATCATCAGCCCTCTCCTCATCACCTGCACCGACCCAGCCACCTTGGCTATCCGCCAGTGGTGCAGCCCATCCAGCCACCCGCCCTGATGCATCCACAACCCTCGCCGGGATCCCAGTCGCACCTGGACCACCTTCCCACGCCGGGTCAGCTGCCGCCTCGCGAGGATTTCTTCGCCGATCGGTTCCCGCTCAACTTCACAACCGCCAAGACCCTGTCGCCGGAGCACCACTCCCCGGTGCGCTCGCCCGCGGGCGCTGGTGTGCCTCCACCTGGAATTCCTCCGCCACACCACCATCCTCACCACATGGCCAGGTCGCCTTTCTTCAATCCCATCAAACACGAGATGGCCGCTCTGCTTCCGCGTCCCCACAGCAACGACAACTCCTGGGAGAACTTCATCGAGGTGTCGAACACCTCGGAGACCATGAAGCTGAAGGAGCTGATGAAGAACAAGAAGATCAGCGATCCCAACCAGTGCGTCGTCTGCGACCGCGTCCTGTCCTGCAAGAGTGCCCTCCAGATGCACTATCGCACCCACACCGGCGAGCGTCCCTTCAAGTGCCGCATCTGCGGCAGGGCCTTCACAACGAAGGGCAATCTGAAGACACACATGGCGGTGCACAAGATCCGTCCGCCAATGCGCAACTTCCACCAGTGTCCGGTGTGCCACAAGAAGTACTCCAACGCCCTGGTCCTGCAGCAGCACATCCGCCTGCACACCGGAGAGCCCACTGACCTGACGCCGGAACAGATCCAGGCGGCTGAGATCCGGGATCCGCCTCCTTCGATGATGCCGGGGCACTTTATGAATCCCTTCGCAGCTGCCGCCTTCCATTTCGGAGCTCTGCCTGGAGCAGGAGGTCCTCCAAACCCCAACCACATGCACAACGGAGCCCTCGGATCGGAGTCCTCGCAGGGCGACTTGGAGGATAACATGGACTGTGGCGATGACTACGACGACGACGTCTCCTCGGAGCATCTGTCGAACAGCAAtctggagcaggagcagggcgAGAGACCACGATCAGGGGACGACTTCAAGTCCCTGCTGTTTGAGCAGAAACTGAGGATCGATGCCACGGGAGTGGTTAATACGAATCCTGTGCGACCGCGGTCTTCGGCCTCCAGCCATGGCGGCCACTCTGCGGGCTCTACTTCGGCCCCGACCTCGCCCACCACCACGTCGGCTGTCGTCCAGAAGCCCAGTGCCTCGCCTGCCCGGTCGGAGGCCTCCCAGGGAGCTCTGGACTTGACTCCTCGAGCCCAGCCTGCCGCCAGGTCTCCTCTGCCCGCCTCCATCGACAAAAAGCCCGTTATCAGCAGTCCGCCCAGCTTGCCACGCAGTCCCAACCACGGTCCCACCTCGCTGCTGACCTCCCCGCTTCCCCCAAGCGTCGGCATCGACTGCCTACCCCCGGGCCTGCAACACCacttgcaacagcagcaccagcacctcATGCACCAGCAGGCAGCCgtggcagcagcggcggccgCCCAGCACCATCATCACCAGCAGATGGCGGCTCTGCACCAGCACCAGGAGCAGCTCCGTCGGGAGGCGGCCGAGGCACAGCAGAAGgctgcagcggcagcagcggcggcggcagcagcagcggcagccgcCCAACGCCAGACCTCCCCTCAACCCACCCAGCCGCAAAGGCCGGGAGATGGGGGAGTGGGCCAGCCACCCAATCCGATGATGGGCGCCCGGCCGCCTTTCGGCATGTTCCCTAACCTGCCGCTCTTTCCGCCCGCCACCACCCAGAACATGTGCAACGCCATGAACCAGATCGCTCAGTCGGTGATGCCGGCAGCTCCGTTCAATCCTCTGGCTCTGAGCGGTGTGAGGGGCAGCACCACCTGCGGCATCTGCTACAAGACATTCCCCTGCCACTCGGCCTTGGAGATCCACTACAGAAGCCACACCAAGGAGCGGCCCTTCAAGTGCAACATCTGCGATCGCGGCTTCACAACCAAGgGCAATCTCAAGCAGCATATGTTGACCCACAAGATTCGCGATATGGAGCAGGAGACCTTCAGAAATCGTGCCGTAAAGTATATGAGTGACTTGAACGCCGATCGCGAATAA
Protein Sequence: MKNHLSNVLCAMRSDFKDNHQETINKMIQFGTVKYGIVKQLKDRARSADKDTGSDQEENGGCSPLTTATTTASPSRSPEPEDQDHHDQDQDHQVSSPLTEQVEKPFETLQQKTEIEPIEDNNNKVEMTKPNSEDRDRDREREPNASGSMPSSPVAEASAEEAATERAPEKEKDIEVDVEMEMADEPRSVLPATEMGSLPGAAGAPVTLEAIQNMQMAIAQFAAKTIANGSTGADNEAAMKQLAFLQQTLFNLQQQQLFQIQLIQQLQSQLALNQAKQSEDDQEEEPEQDVEQDQELETDTYEEEERIADMELRQKAEARMAEAKARQHLINAGVPLRESSGSPAEALKRRREHDQESQPSRRLSSEACIKRENHSQQDALAKLKDLENTPLPFGSDLASSIITHHDDLPEPNSLEMLQKRAQEVLDSASQGILANNMADDFAFGDKSGDGKGRNEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTKGNLKVHFQRHAQKFPHVPMNATPIPEHMDKFHPPLLDQMSPTDSSPTHSPAPQSGPFGSAFPGLQNLYRPPMEILKSLGAGAPHPFFPQDLPTDLRKPSPRLQEEEEAMEAVPVKREIVEEEKNAHQQQQCEQEERALSQREEEQDNRNSSPEPEPLPLEVRIKEERVEDEPEQEPVQKEERRSPSPLHHHQPSPHHLHRPSHLGYPPVVQPIQPPALMHPQPSPGSQSHLDHLPTPGQLPPREDFFADRFPLNFTTAKTLSPEHHSPVRSPAGAGVPPPGIPPPHHHPHHMARSPFFNPIKHEMAALLPRPHSNDNSWENFIEVSNTSETMKLKELMKNKKISDPNQCVVCDRVLSCKSALQMHYRTHTGERPFKCRICGRAFTTKGNLKTHMAVHKIRPPMRNFHQCPVCHKKYSNALVLQQHIRLHTGEPTDLTPEQIQAAEIRDPPPSMMPGHFMNPFAAAAFHFGALPGAGGPPNPNHMHNGALGSESSQGDLEDNMDCGDDYDDDVSSEHLSNSNLEQEQGERPRSGDDFKSLLFEQKLRIDATGVVNTNPVRPRSSASSHGGHSAGSTSAPTSPTTTSAVVQKPSASPARSEASQGALDLTPRAQPAARSPLPASIDKKPVISSPPSLPRSPNHGPTSLLTSPLPPSVGIDCLPPGLQHHLQQQHQHLMHQQAAVAAAAAAQHHHHQQMAALHQHQEQLRREAAEAQQKAAAAAAAAAAAAAAAQRQTSPQPTQPQRPGDGGVGQPPNPMMGARPPFGMFPNLPLFPPATTQNMCNAMNQIAQSVMPAAPFNPLALSGVRGSTTCGICYKTFPCHSALEIHYRSHTKERPFKCNICDRGFTTKGNLKQHMLTHKIRDMEQETFRNRAVKYMSDLNADRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00504155;
90% Identity: iTF_00550436;
80% Identity: -