Dmer005460.1
Basic Information
- Insect
- Drosophila merina
- Gene Symbol
- -
- Assembly
- GCA_035047645.1
- Location
- JAWNPH010000030.1:5131209-5132604[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.00021 0.019 15.6 1.5 2 23 170 192 169 192 0.97 2 9 0.00022 0.02 15.5 0.3 1 23 199 222 199 222 0.97 3 9 0.01 0.91 10.3 0.7 1 23 229 254 229 254 0.93 4 9 1.1e-06 0.0001 22.8 0.7 1 23 265 288 265 288 0.97 5 9 0.16 14 6.5 3.8 1 23 301 324 301 324 0.92 6 9 0.0021 0.2 12.4 1.3 1 23 337 359 337 359 0.97 7 9 7.8e-06 0.00071 20.1 0.2 2 23 365 387 364 387 0.94 8 9 0.00032 0.029 15.0 4.5 1 23 393 415 393 415 0.96 9 9 3.9e-06 0.00035 21.0 2.8 1 23 421 443 421 443 0.98
Sequence Information
- Coding Sequence
- ATGCTGCGAAATCTAAGCCGCAGAACGGCTCCGGAACACTGTCGCACCTGTCTGGTCAAGTTGGACAGAAGTGAAACGAAGGAACAGTCCCAGTTTATGGATATTCCAATTAGCCAGGAGCTGGAAAAGCtccttaatattaatatttccaTGGATTCCACGTCGGAGGAGCACTGGTGGCCCAGGATACTGTGCTCCCAGTGCCAGGATATTGTCCAGAGCTTTGAAAAGTTTCGCAGAAAAGCAGAGGACTCTCGGCAACAGTTGCTGGAGTTGCTCAAGGAGGAGAATGAACAGGAGGACGAGGTGGCAGAGCATGAGGAGGATGCCCCAGATCAGGAACCTTACTTCGAGGTGGTCTACGATCACCTGGAGACTCATCTCAATAACGGGCCGGACTCGTTGCACAGCTCAGAGCCGCCAGAACCGCCTGATCCCGACCCAAAACCCGATCCCATTGCGAAAAGGGAAGAGAAATCCTCAAGCAGGAGAGCGAGAAACAGCCTGAAGTGCTCACTGTGCCGGCACAGCTTTGCCAATCAGCTAACCCTTTCGGCTCACATCCGGAAGGTCCACGAAGGTAATAAAAGGCCATTCCAGTGCGACAAATGCGAGAAGGCCTACAGTTTCATGGGCGGCCTTTACACTCACATCCGGGAGGTGCATGCTCCGCTGGAGCGTCGTCATCCCTGCGACCAGCCCGGCTGCGAAAGGATCTACACCAGCCGGGTGGCCATGCAAAAGCACAAGCGACTTAAGCACAATCCCAGAGCTCGGGAGCTGGCGAGGAAGTTTATTTGCGAGCAGTGCGGCGCCAGTTTTAACCAATCGGCCAATCTCAACTACCACCGACGCACCAAACATCCGACCGAGGACGAGGTGGCCGCCAGCGGGGAGCGTTACTTCTGTGAGCCCTGCCAGAAGGAGTTCCATTCGCGCTACACCCTTAGGTATCACACCCTGCAGCAACATGCCGCCGGTGACGAGGGCCAGGAGGCAGCGCTGCCGCACGAGTGCCAGGTCTGTGGCCGCCGGATGGCCAAGAAGTTCATGCTGCTGCAGCACATGCTGATGCACTCCAGCGAGAAGCTGCCCTGCGAGCACTGTGGCCGTCAGTTCGCCCGCCGTTTCGAGCTGGAGGCCCATGTGCGGGCCGTCCACCTCAAGCTCAAGCCCTTCACCTGTCGCCACTGCCCGGAGAGCTTCGCGTCGCGGAAAACCCTGCGCCATCACGAGTACATTCACACCGGGGAGAAGCCGTATGTTTGCGACACCTGCGGCCAGGCCTTCCGACAGCAGACGTGCCTCAAAAACCATCGCAAAGTCCATGAAAAATAG
- Protein Sequence
- MLRNLSRRTAPEHCRTCLVKLDRSETKEQSQFMDIPISQELEKLLNINISMDSTSEEHWWPRILCSQCQDIVQSFEKFRRKAEDSRQQLLELLKEENEQEDEVAEHEEDAPDQEPYFEVVYDHLETHLNNGPDSLHSSEPPEPPDPDPKPDPIAKREEKSSSRRARNSLKCSLCRHSFANQLTLSAHIRKVHEGNKRPFQCDKCEKAYSFMGGLYTHIREVHAPLERRHPCDQPGCERIYTSRVAMQKHKRLKHNPRARELARKFICEQCGASFNQSANLNYHRRTKHPTEDEVAASGERYFCEPCQKEFHSRYTLRYHTLQQHAAGDEGQEAALPHECQVCGRRMAKKFMLLQHMLMHSSEKLPCEHCGRQFARRFELEAHVRAVHLKLKPFTCRHCPESFASRKTLRHHEYIHTGEKPYVCDTCGQAFRQQTCLKNHRKVHEK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00550416;
- 90% Identity
- iTF_00504158;
- 80% Identity
- -