Basic Information

Insect: Drosophila merina
Gene Symbol: su(Hw)
Assembly: GCA_035047645.1
Location: JAWNPH010000002.1:8452347-8455324[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00033 0.03 15.0 1.8 1 20 217 236 217 238 0.94

2 12 2.3e-06 0.00021 21.8 0.4 3 23 289 310 287 310 0.93

3 12 0.047 4.3 8.2 0.1 1 23 316 338 316 338 0.95

4 12 4.4e-07 4.1e-05 24.0 2.4 1 21 345 365 345 366 0.95

5 12 5e-06 0.00046 20.7 1.0 2 23 378 399 377 399 0.96

6 12 8.5e-05 0.0078 16.8 5.3 1 23 410 432 410 432 0.99

7 12 6.6e-05 0.006 17.2 0.9 1 23 438 460 438 460 0.97

8 12 4e-05 0.0037 17.8 0.4 1 23 466 488 466 488 0.98

9 12 1.2e-06 0.00011 22.6 2.5 1 23 494 516 494 516 0.98

10 12 4.7e-05 0.0043 17.6 0.5 1 23 520 542 520 542 0.97

11 12 5.7e-05 0.0052 17.4 1.5 1 21 550 570 550 574 0.92

12 12 5.3e-06 0.00048 20.6 0.4 3 23 597 618 595 618 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00033	0.03	15.0	1.8	1	20	217	236	217	238	0.94
2	12	2.3e-06	0.00021	21.8	0.4	3	23	289	310	287	310	0.93
3	12	0.047	4.3	8.2	0.1	1	23	316	338	316	338	0.95
4	12	4.4e-07	4.1e-05	24.0	2.4	1	21	345	365	345	366	0.95
5	12	5e-06	0.00046	20.7	1.0	2	23	378	399	377	399	0.96
6	12	8.5e-05	0.0078	16.8	5.3	1	23	410	432	410	432	0.99
7	12	6.6e-05	0.006	17.2	0.9	1	23	438	460	438	460	0.97
8	12	4e-05	0.0037	17.8	0.4	1	23	466	488	466	488	0.98
9	12	1.2e-06	0.00011	22.6	2.5	1	23	494	516	494	516	0.98
10	12	4.7e-05	0.0043	17.6	0.5	1	23	520	542	520	542	0.97
11	12	5.7e-05	0.0052	17.4	1.5	1	21	550	570	550	574	0.92
12	12	5.3e-06	0.00048	20.6	0.4	3	23	597	618	595	618	0.96

Sequence Information

Coding Sequence: ATGAGCGCCTCGAAGGAGGGTAAGGAGAAAAAGCCCGTCACTGTGGTGAAAATCGTCGAAGTGGAGTCTGCTGCTTCGTCGAAGGACAAGCGACCGACCCGCATGAAACTTCTGAACGATGTCTCGGCAAGCTCGCCGCAAACGTCTCCCACAAAGACGGATAAACGCGTTGGCATTCGGGGAGGACGCGTAAAAATACTCAACGAGGAGGTTATGGTGACTCCAAAGGTAGAGAAAAGGCGATCCACGAAGCCCAGCAGCCCCGTGTCCACCTCGACAGTGAAGATCCTCAATGAAAAGAGGATCGTGCCTGCCGAAGACACTGCACATGAGACTACAAAGATTAAAATTTCACCTCCAAAGAGAAACAAAATGGATCACTACGTACTCCAGGCAGTAAAGGTTGAAAATAGCAAGTCTGCTACCCAATCTACAGCTTCCGAACCCCAAGAGGACGAAGACACCATAGCCTTTATACTGGGGGACGACGATGAAGTGGTTCCAGCATCCATAAGCCGATCGAATGGACAAGAGATCTTGGTGaccgaagaggaggaggaagaggacAATGACTTGGGCGACGAGGGCGACTCACCAGTGGGCAGTAACAAGAATTCCGATCACAAGGCCATGAAAGAGATCGTGGAGCACGTTTGTGGCAAGTGCTACAAGACCTTTCGCCGGCTAATGAGTTTGAAGAAGCATCTGGAGTACTGCCGCTACGATAGCGGCTATCATTTGCGAAAAGCTGAGATGCTGAAGAATCTAGACAAAATCGAAAAAGACGCAATTGTCTTAGAGAAGAAAgacatttgtttttgttgctgtgaAAGTTATGATACTTTCCATCTGGGCCACATCAACTGCCCCGACTGCCCCAAGTCGTTTAAAACGCAGACCAGCTACGAGCGGCACATTTTCATCACTCACTCGGAGTTCAGTGACTATCCCTGTTCCATTTGTAATGCGAACCTTCGCAGCGAGGCCTTGTTGAAGTTGCATGAAGAACAGCACAAATCGAGGGGCAAGCCGTACGCCTGCAAGATCTGCGGCAAGGATTTCACGCGCTCCTATCACCTCAAGCGCCACCAAAAGTATTCTTCCTGCTCGGCCAACGAGAACGACACAATGAGCTGCAAGGTGTGCGACCGGGTCTTCTACCGATTGGATAATCTACGATCCCATTTGAAACAGCATCTTGGCACTCAGGTCGTGAAGAAACCTGAATACATGTGTCATGTGTGCAAGAACTGTTTTTACAGTCTTTCAACGCTCAAcatCCATATCCGCACACATACTGGAGAGAAACCCTTCGATTGTGATTTATGCGACAAAAAGTTCTCCGCTTTGGTGGCTCTCAAAAAGCATCGGCGCTATCATACTGGAGAAAAACCCTACAGTTGCACTGTGTGCAGCCAAGCCTTTGCCGTCAAGGAGGTGCTTAATCGCCACATGAAGCGGCACACTGGCGAGCGACCGCACAAATGCGAAGAATGTGGCAAGAGCTTCATTCAGGCCACTCAGCTACGCACACATTCCAAAACCCACATTCGTCCCTACGCGTGCGATTTGTGTGAAGAGAAGTTTAAGACCGAGAAACAACTTGAACGCCACGTTAAGGAGCACAGCCGTCAAAAACGAGCTGTATTTTCTTGTACTGAATGCAAGCGTCATTTCCGCAACACAGCCCAGCTTAAGCAGCACATGGATGCCGGTGACCATTCTCCCGTAGAAAAACCGCAACGTACTGCGTCGAAGAGAACTGCCAAGGTAATTGAGCGCACGGATTGCGCCATTTGCGACAAAAACTTTGACAGTAGCGAAACCTTACGCAAGCACATTCGTTCTGTCCATGAATGCGATCCGGATGACATTTTTGGCATTCAACCGCCGAAAAAGCGTTCCAAAAACAAAGTAACAAAGGTTGATGAAGACGAAGTAGTGCCAGTGGCACTGAATGCATCATCCAGTTCGTTGATATCTAGCCAAACGGACGATAATGGTGTAGTGGTGCGGGAGTTCTTGGTGGATGAAGCCGATGGTACTGCCCAGACCATtaccttggaaaacgaaaCCTATACCATTCTACCATTAGATGGAGCTGTCGAGGGCGAGCAAATCACAGACGAAGGTGTCAAGGTGGAGGGCCAGAAGTCACCGGCAAAGAAATCACCGCTTGTTAAGAAAGAGAAACGAAAGTCTTTGGGTGCAAGCTTAGCTGCTGCAATTGCCGATAACATTGAAATACCCCAACTCGAGGATGAAATTGAGGGCGAAATTCTAACCGAGGAAGATCTTAAACTAAAAGAAAACATATCCAAGCTGATTGACATGCTGGTGGACCCGCCTATCTTGAAGAAATACGGTTGGCCTAACGCTCCCGAGGAAATGGTGCTCTGCAAGGTGATAGAAAACTGTGGCTATGATCTGAAGAAAGGATCAGAAAACTACGAAGAGTTAGACTACGGCAGCAGGATGAGAGAGTATTGCAAACTATTGTTCACGGTGGTCATTCACAACGATTCCATCAAGTCCCTGTTGAACAATTTCCCCATCGACGATGTGATCGAATATGTTCTGGGGGATGAGGACCAAGATGACGAAGGAGATACCAAGGAAAAGGAAGTGAAAGGCAAAACTGGTCCTAAGACGGTTAcagcaaaaaaggaaaaggaaacgGTTGCATGA
Protein Sequence: MSASKEGKEKKPVTVVKIVEVESAASSKDKRPTRMKLLNDVSASSPQTSPTKTDKRVGIRGGRVKILNEEVMVTPKVEKRRSTKPSSPVSTSTVKILNEKRIVPAEDTAHETTKIKISPPKRNKMDHYVLQAVKVENSKSATQSTASEPQEDEDTIAFILGDDDEVVPASISRSNGQEILVTEEEEEEDNDLGDEGDSPVGSNKNSDHKAMKEIVEHVCGKCYKTFRRLMSLKKHLEYCRYDSGYHLRKAEMLKNLDKIEKDAIVLEKKDICFCCCESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFSDYPCSICNANLRSEALLKLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCSQAFAVKEVLNRHMKRHTGERPHKCEECGKSFIQATQLRTHSKTHIRPYACDLCEEKFKTEKQLERHVKEHSRQKRAVFSCTECKRHFRNTAQLKQHMDAGDHSPVEKPQRTASKRTAKVIERTDCAICDKNFDSSETLRKHIRSVHECDPDDIFGIQPPKKRSKNKVTKVDEDEVVPVALNASSSSLISSQTDDNGVVVREFLVDEADGTAQTITLENETYTILPLDGAVEGEQITDEGVKVEGQKSPAKKSPLVKKEKRKSLGASLAAAIADNIEIPQLEDEIEGEILTEEDLKLKENISKLIDMLVDPPILKKYGWPNAPEEMVLCKVIENCGYDLKKGSENYEELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDDEGDTKEKEVKGKTGPKTVTAKKEKETVA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00550375;
90% Identity: iTF_00504114; iTF_00615027;
80% Identity: -