Basic Information

Insect: Drosophila meridionalis
Gene Symbol: -
Assembly: GCA_035045145.1
Location: JAWNPG010000054.1:338279-353523[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 6.3 4.4e+02 1.8 3.8 3 23 312 334 310 334 0.92

2 15 2.3 1.6e+02 3.1 0.9 3 21 473 491 471 495 0.91

3 15 0.26 18 6.1 1.4 2 23 517 539 516 539 0.91

4 15 0.17 12 6.7 0.8 1 23 556 579 556 579 0.95

5 15 0.2 14 6.4 0.2 1 21 584 604 584 608 0.91

6 15 0.026 1.9 9.2 0.3 2 23 661 683 660 683 0.93

7 15 0.34 24 5.7 0.2 1 21 688 708 688 709 0.92

8 15 1.7 1.2e+02 3.5 0.4 2 23 728 749 727 749 0.90

9 15 0.0001 0.007 16.8 3.0 2 23 762 782 761 782 0.97

10 15 0.0025 0.18 12.4 1.7 1 23 788 811 788 811 0.95

11 15 0.00012 0.0087 16.6 4.3 1 23 838 860 838 860 0.98

12 15 0.36 25 5.6 0.3 1 23 867 891 867 891 0.93

13 15 0.69 48 4.8 6.9 1 23 896 920 896 920 0.97

14 15 0.0089 0.62 10.7 5.9 1 23 929 951 929 951 0.99

15 15 0.0095 0.67 10.6 5.5 1 21 957 977 957 982 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	6.3	4.4e+02	1.8	3.8	3	23	312	334	310	334	0.92
2	15	2.3	1.6e+02	3.1	0.9	3	21	473	491	471	495	0.91
3	15	0.26	18	6.1	1.4	2	23	517	539	516	539	0.91
4	15	0.17	12	6.7	0.8	1	23	556	579	556	579	0.95
5	15	0.2	14	6.4	0.2	1	21	584	604	584	608	0.91
6	15	0.026	1.9	9.2	0.3	2	23	661	683	660	683	0.93
7	15	0.34	24	5.7	0.2	1	21	688	708	688	709	0.92
8	15	1.7	1.2e+02	3.5	0.4	2	23	728	749	727	749	0.90
9	15	0.0001	0.007	16.8	3.0	2	23	762	782	761	782	0.97
10	15	0.0025	0.18	12.4	1.7	1	23	788	811	788	811	0.95
11	15	0.00012	0.0087	16.6	4.3	1	23	838	860	838	860	0.98
12	15	0.36	25	5.6	0.3	1	23	867	891	867	891	0.93
13	15	0.69	48	4.8	6.9	1	23	896	920	896	920	0.97
14	15	0.0089	0.62	10.7	5.9	1	23	929	951	929	951	0.99
15	15	0.0095	0.67	10.6	5.5	1	21	957	977	957	982	0.93

Sequence Information

Coding Sequence: ATGAACCCGCAGTCGGACGACCTGGATGATACGCACCTCTGCATTAAGTGCAATGCGACAATTGTGGGTCTGCGCAAATACATCGATCACCGCAAACAGAATTGTCTGAGAATTGTGGGAAATAGTCGGAAGGAGAAGCAGTTGGTGGCTACGACGACGACATCTTCGGTTAGAACTCATGTGACGTCCACGATCATAAGTCGCCCCAACTTGGAGCAAGGCTACGATGGGTTCCACTTTTCCGAGCCGGAGGCACCGAGCAGCTACCTGCGCAAGACGACGGCCAGTCATGGCGGCAAGACGTCCAAGGCCCTCACTGAGGCCTATGATCCAACCTACGAGCTGGGCGCCGATCTCTTCTTCTcctcgctgcagctgcagagtGTCTCCACGGGCGGCAAGACGGGTACACGGCCCGAACGGGGCGCTAAAGAGGATCAGAGCTGGCATTCAACGAGCAACTGTTCCGATCCATTGCTGAAGGCGGTGCGGGAGCATGAGGAATCCGTCTTCAAGCCACTGAAGTTCGTGCACTCGCCCGAGGCGAGCGACGACGAGGAAGATGACGAGGAGCCCGATGAATCTGATGGCGACGACGAGGAGGCAGATCCGCTGCAGGAGCATGAACACGAGCAGGACCCAGAACATGATCCCGATCCAGATCccgatgaagatgatgatggcCAGCGGCACTCGCCGCCTGCCGTTCCTGCCACGCACACAGGTGGCAAGTGGAAGCCGGAGCATCGGCCGCAGCTGCGCCACACCCACCTAGAACGCATCTCGCCCAGCTGGGATGAGCCACCCGAAGATGCGCACGACCATCCGCCAGCCGAGCACACGCACGGCAAGTGGGTGCCAGGCAGCAAGCAGCTGGAGTACCGCGAGAACATCGATCTAACCAAGCTCAAGCAGCCCGACGCCAAGTATTGGTGCAACATCTGCTGTCGTCGCCTCAAGTCCCGACCTAACTACGCTCACCACCTGCGCAGCAGCTACCACAAGAAGCGCGCGGACGCAGAGTGCCAGCTGGAGCGGGCCAAACTGGAGGCCGCTAACCTGAAGGTCGGCAAGCACTTTGTCGAGCGCTCGGCTCCGGCAACGGAGCAAGTGCAGCGACATCGTCGTCGCACCAACTTCTTACGCTGCGATCTGTGCCGGCACACCATGGCGCGCCATCTCATAGGCAAGCATCTGATCTCCCACTACCACTACCGCCGCCTGCGACAGCAGGACAATCTGCGCAACGAGACCTGCCTGCAGGCCATCCTGGATCACATGGGCAGCATTGTGCGGCAAGCGCCGTTCCAGTGCCTGCCCTGTCGGTTCTACGCCAACACAGAGCAGACGTTTCAGGCGCATTGGCAATCGTCCGAGCACATTGAGCTGACCAACCGGCTGGGCGGAAGCTTCTGGTGCAGCTACTGCCAGTTCGAGTGCGGCAGCAACGACGAAATGTGGCAGCACCTCCTGGGCAACACGCACATGGAGGTGCTGCTTGCGATCAATCGATCGGTGCCCGTTTGCAttgggcagcggcggcggctctGCTGCTCCGTGTGCAACGCCAGGTTTCTGTACAACGCGCAGCTGCGACGCCACTTCGCCTCGGAGCATGCGGGCGTGACACCCACGGGCAGCGCCTCGGACGACTATCAGTGTCGCTTCCGCTGTGGCGTCTGCGGCGCTGCGCAGAGGTCGCGCATGGCGCTGCAGCGCCACGAGAAGCACAAGCACCGCCTGAACAAATATTACTGCGCCCTCTGCCAGCTGGAGTTCGAGACACCGCAGGCCGCGCGTCGGCATCGCAGTCAGATGGTGCACAAAGAGAACGCGGAGCGGCGTCGGGATAGCCGCAAATGCGGCAACTCCGAGGTTCCGGAGGGCGAGGATGAGCTGGAGCACATGCTGCGCGAAGTGCTGGGCGAGCCGCCGCCGGAGCAGCCGTCAACGAGTGCCGAAGGCCGGCTCTCAAACCAGCAATGCGTCAATTGCCAGCAGCGCTTCGGGTCGGCCCAGGCGCTGACTCAGCATCGCAGCGAGGCCCATCCCATGGAGAACCACGCCTGCCtcagctgcggcagcagcttcCAGTCCGCCCAGGCCCTGGGCCGGCACACGCGCAGCTGCCAGCCCATGGCCTCGGTATCGACAGCCGCGGAGTCGCCCTCGAGCCAGTGGAACTGCGATCAGTGCGGCTTCAGCGCGCAGTACGAGTCCGACCTGCTCTACCATCGCTTCTTCCACATAATCGGCCCGACCATTGGCAAGGACGAGCTGCTGCAATGTCCGCGCTGCCCCAAGCGCTTCCGCAAGCACTCGCTGCGCGCACACCTGCGCAATCACACGAACGAGCGCATCTTCGAGTGCGCCCAGTGCTTGTCCAAGTTCGCCAGGCGACACAATCTCAAGAGCCACATGGAAAACGTTCATAGCGAGCGGGAGAAGTCGGAACCAGCTGCCAAGACAACGGGTAAGCGGCGGACAGCTAAGTCAACGACGGATTTGAAATTCGAGTGTACCACATGCTGGAAAACATTTACCAAAAAGCATTCACTTAAACTGCACGAAATGAGCCACGCCAAGGTGAAGCGTCAATTCCATTGCCCCCGCGAGGACTGCTCATACGCTGGCCTCACCAATGAAGGCCTCCAAGTCCACATGAAGTCCCACTCCCTCGGCAATCACAAATGCAAACACGAGAACTGCCAGTATGTGGGCAAAAGTGAGCTGCACTTGAAGCGGCACCTCAAATCACATGCTGACCTGACCCATGCTGAACTGTACAAGTGCGATCGGTGTGAGTTTAAGGCACGAGTCAAGGGTCACCTGCATCGTCACATGCGCAAACATACCGGAGAAAAGCCCCATCAATGTCCTCACTGCAGCTTCCAGTGCAGCAGCTTCGACAATCTGCGCAAGCATATTATAAAGACGGGCAAACATCCGGGCAAGTTCATCTACGAGTGCTCTAGCTGTAGTGCATTTAAGAGCAACAGCTATAAGGACTATCAAAATCACTTGATCACACATAACCCGGAGGAAGCTCCATAA
Protein Sequence: MNPQSDDLDDTHLCIKCNATIVGLRKYIDHRKQNCLRIVGNSRKEKQLVATTTTSSVRTHVTSTIISRPNLEQGYDGFHFSEPEAPSSYLRKTTASHGGKTSKALTEAYDPTYELGADLFFSSLQLQSVSTGGKTGTRPERGAKEDQSWHSTSNCSDPLLKAVREHEESVFKPLKFVHSPEASDDEEDDEEPDESDGDDEEADPLQEHEHEQDPEHDPDPDPDEDDDGQRHSPPAVPATHTGGKWKPEHRPQLRHTHLERISPSWDEPPEDAHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLKQPDAKYWCNICCRRLKSRPNYAHHLRSSYHKKRADAECQLERAKLEAANLKVGKHFVERSAPATEQVQRHRRRTNFLRCDLCRHTMARHLIGKHLISHYHYRRLRQQDNLRNETCLQAILDHMGSIVRQAPFQCLPCRFYANTEQTFQAHWQSSEHIELTNRLGGSFWCSYCQFECGSNDEMWQHLLGNTHMEVLLAINRSVPVCIGQRRRLCCSVCNARFLYNAQLRRHFASEHAGVTPTGSASDDYQCRFRCGVCGAAQRSRMALQRHEKHKHRLNKYYCALCQLEFETPQAARRHRSQMVHKENAERRRDSRKCGNSEVPEGEDELEHMLREVLGEPPPEQPSTSAEGRLSNQQCVNCQQRFGSAQALTQHRSEAHPMENHACLSCGSSFQSAQALGRHTRSCQPMASVSTAAESPSSQWNCDQCGFSAQYESDLLYHRFFHIIGPTIGKDELLQCPRCPKRFRKHSLRAHLRNHTNERIFECAQCLSKFARRHNLKSHMENVHSEREKSEPAAKTTGKRRTAKSTTDLKFECTTCWKTFTKKHSLKLHEMSHAKVKRQFHCPREDCSYAGLTNEGLQVHMKSHSLGNHKCKHENCQYVGKSELHLKRHLKSHADLTHAELYKCDRCEFKARVKGHLHRHMRKHTGEKPHQCPHCSFQCSSFDNLRKHIIKTGKHPGKFIYECSSCSAFKSNSYKDYQNHLITHNPEEAP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00544823;
90% Identity: iTF_00544823;
80% Identity: -