Basic Information

Insect: Drosophila meridionalis
Gene Symbol: -
Assembly: GCA_035045145.1
Location: JAWNPG010000020.1:82982-90363[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.025 1.8 9.3 1.9 1 23 1128 1150 1128 1151 0.95

2 8 4.8 3.4e+02 2.1 1.0 1 23 1156 1179 1156 1179 0.96

3 8 0.00036 0.025 15.1 0.8 1 23 1407 1430 1407 1430 0.96

4 8 0.0046 0.32 11.6 0.5 2 23 1439 1460 1438 1460 0.97

5 8 0.045 3.2 8.5 0.3 1 23 1467 1490 1467 1490 0.96

6 8 1.8e-05 0.0012 19.2 1.4 1 23 1496 1518 1496 1518 0.97

7 8 0.00022 0.016 15.8 0.6 1 23 1523 1545 1523 1545 0.97

8 8 0.0049 0.35 11.5 3.4 1 23 1551 1573 1551 1573 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.025	1.8	9.3	1.9	1	23	1128	1150	1128	1151	0.95
2	8	4.8	3.4e+02	2.1	1.0	1	23	1156	1179	1156	1179	0.96
3	8	0.00036	0.025	15.1	0.8	1	23	1407	1430	1407	1430	0.96
4	8	0.0046	0.32	11.6	0.5	2	23	1439	1460	1438	1460	0.97
5	8	0.045	3.2	8.5	0.3	1	23	1467	1490	1467	1490	0.96
6	8	1.8e-05	0.0012	19.2	1.4	1	23	1496	1518	1496	1518	0.97
7	8	0.00022	0.016	15.8	0.6	1	23	1523	1545	1523	1545	0.97
8	8	0.0049	0.35	11.5	3.4	1	23	1551	1573	1551	1573	0.99

Sequence Information

Coding Sequence: ATGGTGGCTAAGTTTCGGCGGCGCTGCTTGCGTGTGCAGCTGCGCCTGGAGGAGTATGCCAAGAAGATAGCCGAGCGTAAGCAACGTGTGGCTGCCAAGCTGGATAGACTAACACAGTCCAATGATGTACCTGCAAAAGATTATCTTCATCTGCCTGAGATGCAAACGGAGCGCAAACGGCGTCTGGACCTCAGCATGGACAAAGCAAAGTCggaacagcagccgcagctcaaAGTATCCAAGATTGAAGTTGATGCAGAAGTGCCGACGGCGTCCAGTGTCCAACTCCTACAGCTGCGTTCGCGTAAAATGCGAACTGCCTCGTTGCCAGCCAACAGACTAGAGACTGAACCTTCGCCGGCGATAGCGACACGAAGTGCTTCCCAGCACGGCGAAGTAAGATTAAGGGGCCGAACGCCACACAAATCGCCTTGCAAACGAGTTCACGTGCCCTGGAAAACGAAAGCGGCACGCAAACAGCTTTCCGAAACGTTGTCGAGCTGCTCGACAGACACCACGATGCCGGAGGAGCAGCCAAAGGTAGAGTTGCTAACGTTTTTATCAGCGCCGAGCTCCGAAACTGAGACGGAATCAAGAGCTGGCCAATCGACACCGGAGCAGCTCAGCGATTTGTCCGTGAATCCATGCCACGGCTTTGACGTCGTTGGCCACAGCTGCTCTTCCACAACTTCGTCCTGGTCATCCGATtcatcatcagcagctgcGATCACTGGCCAGAAAACAACACCTAAATCGAACTCCAAGCTGAAGTTTCCACCAAAGCGCAGGTCGCCCAAGAAACTCAAGGTGCTGCGCTGTGGACGTAAAGCGCGAGTAACAGTCAACTCTGTGCCGTTCAAGAGATCAAAGTGCACCACAGAGGAGAAGCAGATGCAGAGAGTTGACGAGCAGCAATTGCCCGAAGAATTGTCCATGATAGACCAGTCCAGCAATACATTAATGGAGACCTCCTCTGTGGACGCAATCGCAGGGGAGACGGAGGAGAAGTTTGCACATAGCTCCTCGGCTGAGGTGCCGAATGCACACACAGAAACCAACTCGGAGAAGCAGCATCCAATCCCAGAAGATGAACCACAGGTGGACTCAAGCGAAACATCAGCGGCGACAGCTGCTGAGAGTGATGCGGTGCAGACTAGTGTAGAGATGAGAGAGTTCACCGAACAGCCGAAAATCGCTGCAGCTGAACAAGTGCAGTCGCCAGCGCCGTCAGAGCCAATCAAATCGTCTCTAGACAATGAGATCAGAGAAACTCAGGCCACGATGCCAACAGAGCAAATAGGAAGCATATCAGAGGAAGTTGTGGGTGAAATTGCTCCAACGAATGGAATTGCAGAGTCAGCTGATTCGACGGTGCAATTCGAAGAGCTGACGTCGTCCACCATGGAGCAGGGCAGGCAGTCCCTGACGCCCGAAGTGCCGACAGCTGAGTGCGAAgtggagctgcagcagatgGACGAGGAGTCACAGTCAGACGACGAGGCCAAGGATTCGAAGCTTAAAGTGAGCATACCCTTGGACGTGCTGGACGATGATCTGCAGCGCAAGCTATGCAACAGCACAGATGCCCCACAGGCTGACGTCGAGCAGCGGGACACCGATTTCAAGGAGCCCGCGGAAGCGGACGACGTGAACAACAATGAGAATGGCGAGAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATGCTGCTGTGGCACTCACATCCAAACAAATTGAAGCAGAGCCCAATGGGGGCGTGACTGTGCTGGCCACAGTGGATGACGACATGGAGTCGCTGGAGCGACTGACCTatatgcagcagctgcagccagtcAACGAAGTGCAGCTGCCGCGTGCTGGGAATTCCAGTTCCATGGACTTTTTAGCGGAATTCGAGAAGCATTGCGAGAAGACACTTAAGCTAcattcgcagtcgcagtcgaagtCGCAGTCGAAGTCGCACTCACAGTCACACTCACAGTCACGCTCACAGTCGCAGTTGGACTTACAGGCGCAGGCGCAGTCGCAGTtacagtcacagtcgcagtcgcagttgcagtcgcagtcgcagttgcagacgcagtcacagtcgcagtcactCAAtgtggaactggaactggtaGAGGCtaagcagcagctggaagTGGAGATGAATGATGTGGAGAGCACGCTGCACGGCATACTCAATGAGATGCAGGATCAGCATCTCTACACGCCAGTCTGCACGCCCATCGATGAGCTGCTGACGCCTGCGGACTATGTGGTGCTCAATGAAACGGAGGCGCCAGTGCCGACGCCAGCAGCTCCACAACTCTATGAGCCGCCAACTGAGGCAGttcagccacagcagcagcagcagcagcaggtgaaGGAGGGCAATCTGTTCGATAGCACTAATTTCAGCAATGAGCTGATTGGCTTCCAAAACGATATGCCGTGCTTCCAGAACATTGAGACGACGCCCGAGTCGATGGCAGCTCAGCAGAgcctgcagctggagctgacGCAGCTGCTCAATGAGCTGCAGCCagcacagccgcagcagccactgcagcagcagccactacagcaacagccagtaatgcagcaacagctgcagctacagCCGGAGGCAGTTAACTATGAGGCACTGTATACGGCAGCGCTgcccgctgctgcagcaaacagcaacaagttGCAATTGATCCAAATGCAGCCACAAGAGACGCTGTGGCAGACTCAGACAACTGTCGCCCCGCAAGCGACGGCCACGCAGCTGCAGTGGTCGACGGTGGGCGGCTTGGAGGCCATCAAGACAGCACCTGTTACCAGCGTGGATGCTCTGGATAGCAGTGGCACCACCACCTACTATATCAGTGCCGCTGATCTCTATCAgacgcagctgcagccgcaaaCCGCGCAGCTAACGGGCGACGGCTATGCGCTGCTGGACAGCAATGAGAATTacgtgcagcagcaactgcagcagccacagtcacagcagcaacagctgcagcagcagcaacccaTTATGATACTCATACAGCAGccggagctgcagcagccggtGGCATCCGCTAGCAAtccgcagcagccgccgctgcacATCGCTTATGGCGCCAATCTGAGCAATGAGCTGCACGCCGCCTttccacagcagcaactgcagcagcagcagcagcagcaggagactcagtctcagcctcagcctcagccacagccacagccacaaccCCAACAAGTACAAAATACAGTATTAAGCTTACCTGCTGCCGTGTCGCCGCCCACACGAGGCCGTCCGTCCATGTTGAAGTGCCGCTTCTGCCAGAATGGACCACGCTTCGCCAACAGCCTGGAGTACAGTCGCCACATTATTGAGCTGCATCCGGCCGTGGCTCCATTCAACTGTCCCCATTGCCCGCTGGCCTTTGCCGGTCGCAACAAGCGCAACCAGCACATCCTTAGCCATCATATAGTGCAGCAGTTCCACTGTGGCCAATGCTCACAGCTGTTGCCCTCTCAGCGTGCTCTGGACTTACACTTGCAACGCTTCCATATGCCGCTGCCCACCGAACCAACAGCTGCTACTGGCGTCCGCCTCGAGGAGGTTCAATTGCAAatagccaacaacagcaacaaaaacaacaaaaccaacaacaacaacaacaacaacaacaacaacagcaacagcagcgaacaGCCCAATCAGCTCcatcagcagcaaccgcagcagcaacttaGGCAAccacaaaagcagcagcaactgcagcataTACCTTCTTTGGAATTGCAAGCGAGTTCCCAACAGCCACGCAGGACGCGCATACTCTGCTGCCCCGACTGCGAGGACTGCTCTTCGGTCAGTGGACACCATCAGGACAGCGGGCAGTCGTCGTATGAGGAGCTGTCGACCTTGCAGCCACCGCCAAATGTTTTGACGCCGCCTTCAACAATCGCATCGCTTCCATCGCCGCAGCCGGCGCCGCACATAACACTGCCTTCGCCGGAGCAATCGGAGCCGGACTCGACGACGGCCACACTGAGGCAGTTCCGCAAGCGCTGCAtgcccagcagctgcacaGCAGCCGGAACTACTGccatggcaacagcagcgacaacaacgacagcagcaaccacaatGCTCTCCACGGCGCCATCGCCGTCGCCTTCGTCATCGCCATCCTCGTCGACAATGGAGACGAGCGCCACATTGCAGATGAGCAAGCTGCGCAGCAACCATCAGTGCGTCGTTTGCGAGAAGCGCTTCACGAACATCATTGCGCTGCGCAAGCACCAGCAGCTGGCCCACGACTCGCAGACAACGATGCCCTGGGTGTGTGGGATCTGCAAGCGTGGCTATCGGAAGCGCACCGACATGGACAACCACATGAAGTCGCACGAGCCGAAGGGCCGGCCGTACGAGTGCAACGAGTGTTGGGTACGTTTTCCGGAGTTCAAGCAGCTGGCCATGCACAAGTTCACCGTCCATGAGCTGATCAAGCCGCACACCTGCGACGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAGTTTCACGGTGAACGCGGCTTCGATTGCGAAGAATGCGGCGAACTATTCGTTTATATGAAAGACTTGCGCAAGCACCGTCGCAGCCACAACAGCGACTTGTTTTACAAATGCGACAACTGTCCGCGCACCTTTCTGCATTTTACGAGTTATCGTGCTCACATAAATACTCACCTGCCGCTGGGAGTGTTTCTCAACGACAAAATGCCCAGCAGCGTAAGCAGCAAACTGGAGAATCCTGCTGCAATGCCGGCAACTATCGAGGACTCCTCACTGCCATTAACGCCGCTCAGCAactgcaatggcaacggcggcagcaTCGATGATTGCCCCGGCTCCGTGGAACTGGTGGAAAGCAGCTTGACGCCATCGCTGGACATGATTGTGGATACGCCGTAA
Protein Sequence: MVAKFRRRCLRVQLRLEEYAKKIAERKQRVAAKLDRLTQSNDVPAKDYLHLPEMQTERKRRLDLSMDKAKSEQQPQLKVSKIEVDAEVPTASSVQLLQLRSRKMRTASLPANRLETEPSPAIATRSASQHGEVRLRGRTPHKSPCKRVHVPWKTKAARKQLSETLSSCSTDTTMPEEQPKVELLTFLSAPSSETETESRAGQSTPEQLSDLSVNPCHGFDVVGHSCSSTTSSWSSDSSSAAAITGQKTTPKSNSKLKFPPKRRSPKKLKVLRCGRKARVTVNSVPFKRSKCTTEEKQMQRVDEQQLPEELSMIDQSSNTLMETSSVDAIAGETEEKFAHSSSAEVPNAHTETNSEKQHPIPEDEPQVDSSETSAATAAESDAVQTSVEMREFTEQPKIAAAEQVQSPAPSEPIKSSLDNEIRETQATMPTEQIGSISEEVVGEIAPTNGIAESADSTVQFEELTSSTMEQGRQSLTPEVPTAECEVELQQMDEESQSDDEAKDSKLKVSIPLDVLDDDLQRKLCNSTDAPQADVEQRDTDFKEPAEADDVNNNENGENFCQSATADSFNAAVALTSKQIEAEPNGGVTVLATVDDDMESLERLTYMQQLQPVNEVQLPRAGNSSSMDFLAEFEKHCEKTLKLHSQSQSKSQSKSHSQSHSQSRSQSQLDLQAQAQSQLQSQSQSQLQSQSQLQTQSQSQSLNVELELVEAKQQLEVEMNDVESTLHGILNEMQDQHLYTPVCTPIDELLTPADYVVLNETEAPVPTPAAPQLYEPPTEAVQPQQQQQQQVKEGNLFDSTNFSNELIGFQNDMPCFQNIETTPESMAAQQSLQLELTQLLNELQPAQPQQPLQQQPLQQQPVMQQQLQLQPEAVNYEALYTAALPAAAANSNKLQLIQMQPQETLWQTQTTVAPQATATQLQWSTVGGLEAIKTAPVTSVDALDSSGTTTYYISAADLYQTQLQPQTAQLTGDGYALLDSNENYVQQQLQQPQSQQQQLQQQQPIMILIQQPELQQPVASASNPQQPPLHIAYGANLSNELHAAFPQQQLQQQQQQQETQSQPQPQPQPQPQPQQVQNTVLSLPAAVSPPTRGRPSMLKCRFCQNGPRFANSLEYSRHIIELHPAVAPFNCPHCPLAFAGRNKRNQHILSHHIVQQFHCGQCSQLLPSQRALDLHLQRFHMPLPTEPTAATGVRLEEVQLQIANNSNKNNKTNNNNNNNNNNSNSSEQPNQLHQQQPQQQLRQPQKQQQLQHIPSLELQASSQQPRRTRILCCPDCEDCSSVSGHHQDSGQSSYEELSTLQPPPNVLTPPSTIASLPSPQPAPHITLPSPEQSEPDSTTATLRQFRKRCMPSSCTAAGTTAMATAATTTTAATTMLSTAPSPSPSSSPSSSTMETSATLQMSKLRSNHQCVVCEKRFTNIIALRKHQQLAHDSQTTMPWVCGICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGERGFDCEECGELFVYMKDLRKHRRSHNSDLFYKCDNCPRTFLHFTSYRAHINTHLPLGVFLNDKMPSSVSSKLENPAAMPATIEDSSLPLTPLSNCNGNGGSIDDCPGSVELVESSLTPSLDMIVDTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00544831;
90% Identity: iTF_00544831;
80% Identity: -