Basic Information

Insect: Drosophila meridionalis
Gene Symbol: -
Assembly: GCA_035045145.1
Location: JAWNPG010000020.1:6300929-6303125[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 3e-05 0.0021 18.5 2.5 1 23 402 424 402 424 0.97

2 7 3.3e-05 0.0023 18.4 0.5 1 23 430 453 430 453 0.98

3 7 0.024 1.7 9.4 2.7 1 23 459 482 459 482 0.94

4 7 1.6e-06 0.00011 22.5 2.2 1 23 522 544 522 544 0.97

5 7 0.00093 0.065 13.8 0.9 1 23 550 572 550 572 0.98

6 7 0.00081 0.057 14.0 0.4 1 23 578 600 578 600 0.98

7 7 0.004 0.28 11.8 5.1 1 22 606 627 606 630 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	3e-05	0.0021	18.5	2.5	1	23	402	424	402	424	0.97
2	7	3.3e-05	0.0023	18.4	0.5	1	23	430	453	430	453	0.98
3	7	0.024	1.7	9.4	2.7	1	23	459	482	459	482	0.94
4	7	1.6e-06	0.00011	22.5	2.2	1	23	522	544	522	544	0.97
5	7	0.00093	0.065	13.8	0.9	1	23	550	572	550	572	0.98
6	7	0.00081	0.057	14.0	0.4	1	23	578	600	578	600	0.98
7	7	0.004	0.28	11.8	5.1	1	22	606	627	606	630	0.91

Sequence Information

Coding Sequence: atgaaatgtgctATAATAAGCTGCTCAAACAagttcaaaacaaaacaaaaacactccGAGCAACTGAGTTTCTTCAGTTTTCCCAAAAACCCGGACGTCTTAAAAAGATGGCTTGCATTTTGCCGAAGATACAACAAAGAGAGACTGAAGGCACCCCAAAAGAGCGTCATTTGTAATGAGCACTTTAAAGAGGAGGATATCCAAGGAGCCTTACAGTTTCAAATGGGTCTATGCAGTAAAAGAACGCTGAAACCGGGCGCCGTGCCATGCCTAAATAAAAACGATATGAGTACACTTGAACGGGAGCAAGCTGAAAGGCGCAAGAACAAAAAACTGGTTGCAGAGCTACTTGAGGAAGCGGCAGCACGTGAAGCAGCCGAGGCCAGCGGAGAAATTGTTAAAGCTCCAGACTTCGTCAGAAACACAGGCATTGCTTCGGCCCCCGACTTCGTTAATGCAACAGGCAATGCCTTCATTCCATGTACACCGACACTCCGAGAAAGCGATCCATTGGCAGAAGAACAGGAGGAGCCAGAGTTGGGCGAAGCTCAAAAAGCTGAGCAGATTAAGTGCCGCACCTGCCTTGAACCATTTGTGTTGGATGAAAATGCTAAAGATCTTTCTGATGAAAAAAACGCCGTCATGTTGTTCCACATTGAAGTTATAACCGGTATCTGGaTCCAAGGCAAGGAGGGAATGTTCATGTGCTCAAACTGCGTCCATAATCTGCGCACAGCCATTGATTTTCgagaaaaatgtattcaaacgGAGGTAGAGCTATCACGGTTAGATGCGATTATTAAGGAGACTAGCACAGAAACTCGGAATGCTAATGATGCAGAGATAATTCAGATTAGTGAGAACACTAAAGATTTCGTATCCATATTTCCGGCTGAAAATCAGAATGATCAAACATCTGCAGATGAGCCTTTTTCTTTTGAAGCAGCACAAGTTCCGCCAACATATCCACCAAATGCAGATTCTAATAGTATTGCATTGGGAGCTCAAATATATAAGGATCTTCTTAATGAGTACAGTGGTAAGGACAGAATACCACGTCCACGGCAGATGACAATAACTAGAGAAAAAGTTGTAAAAAAACGTAATCGTACGCCTCGGGAACCTAAACCGAAACAGCCAAAGCGcacaaaagaagaaagaaatcGCATACGTCGTGAGCAAATCAGAGCCATGCCCTTAAACCATGTGTGCGATCAGTGCGGCGCCTCGTTTCGAGTCAGATGTAATTTAACGATCCATATGTTGCGGCACACGCGCACAAAGAACTATTCTTGTCCGGAGTGTCCCAAAAAATTCTACGATGCCTATATGCGAAATATGCATATACGTGTGCGGCACAAGGGCGAATTACcatttgaatgcaaattttgCAGGAAAGCATTTAGCTCGTCCAATACGCGCTATCTACATGAAAAAAAGGTTCATGGAGCATTACCACGTATTCATAGAAACGTGAACCGATTGAACAAAAGGATCGAGCTTAAAAATGAGGAAAAGGAGCATCAACCGCAGGATGAATTGGGTCAAAAGGAGAATGTACGCCACTATTGTACTTATTGTAATAAGAGCTATGCAACAAAATATGCACTTAATTGGCATATCAATATGCACATAGGGCACAAGCCTTTCAAATGCAAGCTCTGCGACATGGGCTTTCCAGATCCTCAATCCAAGAAGAAGCACGAAATGAAGCATGATAGTAAACGTCCCTTTGAGTGCGATATTTGTCTGAAGGGATTCTATGTACGCAACAAGTTAAAGGAACATGAACGAATTCACACAGGCGAACGACCCTATAGGTGTGATGTTTGCAATGCTTTCTTTCGGTACAAGTTTAATTTATGCTCACATCAGTTTAGCAAATTGCATAAGGAGAATGTACAAAAGCTGGAAAAAGTTGAAGTCCTGGAAGATTCAAATTAA
Protein Sequence: MKCAIISCSNKFKTKQKHSEQLSFFSFPKNPDVLKRWLAFCRRYNKERLKAPQKSVICNEHFKEEDIQGALQFQMGLCSKRTLKPGAVPCLNKNDMSTLEREQAERRKNKKLVAELLEEAAAREAAEASGEIVKAPDFVRNTGIASAPDFVNATGNAFIPCTPTLRESDPLAEEQEEPELGEAQKAEQIKCRTCLEPFVLDENAKDLSDEKNAVMLFHIEVITGIWIQGKEGMFMCSNCVHNLRTAIDFREKCIQTEVELSRLDAIIKETSTETRNANDAEIIQISENTKDFVSIFPAENQNDQTSADEPFSFEAAQVPPTYPPNADSNSIALGAQIYKDLLNEYSGKDRIPRPRQMTITREKVVKKRNRTPREPKPKQPKRTKEERNRIRREQIRAMPLNHVCDQCGASFRVRCNLTIHMLRHTRTKNYSCPECPKKFYDAYMRNMHIRVRHKGELPFECKFCRKAFSSSNTRYLHEKKVHGALPRIHRNVNRLNKRIELKNEEKEHQPQDELGQKENVRHYCTYCNKSYATKYALNWHINMHIGHKPFKCKLCDMGFPDPQSKKKHEMKHDSKRPFECDICLKGFYVRNKLKEHERIHTGERPYRCDVCNAFFRYKFNLCSHQFSKLHKENVQKLEKVEVLEDSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516527;
90% Identity: iTF_00545276;
80% Identity: iTF_00545278;