Basic Information

Insect: Drosophila meridiana
Gene Symbol: -
Assembly: GCA_035045185.1
Location: JAWNPF010000020.1:2018945-2021307[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.011 0.84 10.4 2.2 1 23 391 414 391 414 0.92

2 7 0.12 9.1 7.1 2.7 2 23 548 571 547 571 0.91

3 7 0.18 14 6.6 2.0 2 21 583 602 582 603 0.95

4 7 0.9 68 4.4 4.3 1 20 618 638 618 640 0.93

5 7 6.7e-05 0.005 17.4 2.1 1 23 673 695 673 695 0.97

6 7 7.6e-06 0.00057 20.4 1.0 1 23 701 724 701 724 0.96

7 7 3 2.3e+02 2.7 0.5 1 11 730 740 730 747 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.011	0.84	10.4	2.2	1	23	391	414	391	414	0.92
2	7	0.12	9.1	7.1	2.7	2	23	548	571	547	571	0.91
3	7	0.18	14	6.6	2.0	2	21	583	602	582	603	0.95
4	7	0.9	68	4.4	4.3	1	20	618	638	618	640	0.93
5	7	6.7e-05	0.005	17.4	2.1	1	23	673	695	673	695	0.97
6	7	7.6e-06	0.00057	20.4	1.0	1	23	701	724	701	724	0.96
7	7	3	2.3e+02	2.7	0.5	1	11	730	740	730	747	0.81

Sequence Information

Coding Sequence: ATGCCCGCACACTGTGCAGTTGTTAATTGCAGCGATAAATATGTGCATGCGGGCAGCATATCGTTCCACAGATTTCCATTTAAGCGCAAGGATCTGCTGCAGAAATGGAAGGAGTTCACGCAGCGCAGCGGCCAGTGGATGCCCTCCAAGTGGAGCGCCGTTTGCAGTCGCCACTTCGTGGACACTGActtcaactgcagcaacaatcgGAAGACGCTGAAGAAGAATGCGGTGCCAACAGTGCGGCCGCCGGACGATGCCTTGAATGTGCTTGTGGAGCAGGTAACGCGCGCTGTAACGGATACGCCACAGACAACAACGACTGCCGGCACGAGAAGCACCTGCCGCTTCTGTGGCATTGCCGCACTCAATTGCGTCTCGTTTGACAAGAGTTTCGAGCTGTTCGCCATGATCCAGAAATGCTTTCCCACGCTGCAAATCCTGCAGGATGACACGCTGCCCCTGCCGAAGGAAATCTGTGGCGATTGCTGCCGTCAATTGGAGCGTTTCTCCCAATTCTGTGATGTTGTGATCGTGGCTCAGGGCGAGCTGCAGCGAAAATACCGacggcagctgaagatcaagCAGGAGCCGGTGGTGCGGGTCAAGCAGGAGGCGTGCGAAAGTCTTGACAATCTGTTTCCCGACGAGCTGGACATGGGCCTGGACGAGGGCTGCTGCGACCATGAGCCCGATACGAACGACGAGACGGAGCAAAAGTTTCAATTCTGCAATTTTCCCATGCTCAACGCCCAGGACATCATCAACAACTGCGACATCATGGAGATTATCAACCTGGACGATCCGTTCATCAACATCACGGACGATGCGGATGTCGCACAGGCACAGCCCGTCAATGTGCCGGTGCTGCCACAAACGGAGCTGCTCAGCGAGGAGCACAACTATGCCAAGGAGGACTGGCAGCTGCCGCCACTGCAGCAATACAAAACGGAGAAGGTGGAGGGTGCTGAGCCGCAGGAGCAGCCGccatcccaatcccaatccgCTGCTCCCGCTGAGCCGCGCAGCTGCAAGCCCATTGTCACGAATGTCAGCCAGATACCCAATCCGCTGATCTGCGAACTgatgccgccgccaccgctAGCCAGCACCAAGCCCAACATTGTGGTGCTCAACGACAGCGTGGTGCAGTCCTCGGCCTTTCGCCTGCACAATTGCACCTTCTGCACCACGAAGTTCTTCACAGCCGAGAGCCTGCAGCAGCATTACGCCCTGGCACATGCCgcgcccacacccacacccacgccCATGCCCTCGCCCATGCCTATGGTCAGTGTGCCGCCGCCCAATCTTAACCAGACTGCCCACAGCTCACTCAAGCTGGAGTGTCCGCCcgctgcagcaggcgctgGCCTGCCCTTGGCCACGCCCGTGGACTACTGGCAATCGGACTGGCTGCCGCCGCAGCTGCCCGCCAAGAAGAAGATCGACATCCTGGACATGCAGCGCAGTTTCCTGCAGTACAATGATCTGATAGCGGAGCCGGCAATCAGTGCGCCGCAATCCCAGAACTATGCCTACGCCAAGCTGGCCGCACGCTTCAGACGACTGCAGCACACCTGTCGCCAGCTGCGCACGAACCGGAAGTCATTGGCGCAGTCGCGCGCCAATCCTCGCCTGCGCTGCGCCCGCTGTCATCGTCGCTTTGCCagcgtgcagcagctgctgggccACAGGCGACGCAAGCGGCACTTCGGGCTGCCGCCGAAGCGTCTCTTTGCCATGAAGTGCTTCGGCTGCCTGCGGCTCTTCTGCTCCCGACTCGGCCTGCGCCAGCACATGCGCTACATCTGccagtcgctgccgctgcgcaATGCCCGGCTGCAGAGCTACAAGTGCCGGCACTGCCAGAGCATTAGCTTCACGCACTGGCGTTTCTATAGGCGACACGAGCTCAAGTGTCGCCAGCGGCTGCCGCTGAAGCGGGCGGCCAAGCGACGCTGTCGTCCAACTGGTGCAGCCGCTCAGCCTGCACATCATGGCAAACGAACTGTTCACAGCTGCGCCGTCTGCCAGAAGACGTTCAGCTCGCTGACCGGACTGAAGCAGCATCGCATCACGCACAGCTCGGAGCGGCGCTACAAGTGCAGCATCTGCGAGCGCGTCTTCAAGCGGCGCAACGGTCTCTCCCAGCACATCAAGGGCTATCATCTGCAGCTCAAGCCGCACCAGTGTCCCGTCTGCCAGCATCGCTATGCGCTCAAGTGCGACATGCTGCGCTGTCGCCACTCCCAGCGCCGCGGCGCCGCCGCCATCAGTGATCTTGAGCCAGCGAAAACATAA
Protein Sequence: MPAHCAVVNCSDKYVHAGSISFHRFPFKRKDLLQKWKEFTQRSGQWMPSKWSAVCSRHFVDTDFNCSNNRKTLKKNAVPTVRPPDDALNVLVEQVTRAVTDTPQTTTTAGTRSTCRFCGIAALNCVSFDKSFELFAMIQKCFPTLQILQDDTLPLPKEICGDCCRQLERFSQFCDVVIVAQGELQRKYRRQLKIKQEPVVRVKQEACESLDNLFPDELDMGLDEGCCDHEPDTNDETEQKFQFCNFPMLNAQDIINNCDIMEIINLDDPFINITDDADVAQAQPVNVPVLPQTELLSEEHNYAKEDWQLPPLQQYKTEKVEGAEPQEQPPSQSQSAAPAEPRSCKPIVTNVSQIPNPLICELMPPPPLASTKPNIVVLNDSVVQSSAFRLHNCTFCTTKFFTAESLQQHYALAHAAPTPTPTPMPSPMPMVSVPPPNLNQTAHSSLKLECPPAAAGAGLPLATPVDYWQSDWLPPQLPAKKKIDILDMQRSFLQYNDLIAEPAISAPQSQNYAYAKLAARFRRLQHTCRQLRTNRKSLAQSRANPRLRCARCHRRFASVQQLLGHRRRKRHFGLPPKRLFAMKCFGCLRLFCSRLGLRQHMRYICQSLPLRNARLQSYKCRHCQSISFTHWRFYRRHELKCRQRLPLKRAAKRRCRPTGAAAQPAHHGKRTVHSCAVCQKTFSSLTGLKQHRITHSSERRYKCSICERVFKRRNGLSQHIKGYHLQLKPHQCPVCQHRYALKCDMLRCRHSQRRGAAAISDLEPAKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532714;
90% Identity: iTF_00545604;
80% Identity: iTF_00544527;