Basic Information

Insect: Drosophila meridiana
Gene Symbol: L
Assembly: GCA_035045185.1
Location: JAWNPF010000171.1:12703686-12712706[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.0008 19.9 2.9 1 23 161 183 161 183 0.98

2 17 0.36 27 5.6 6.2 1 23 189 211 189 211 0.97

3 17 1.8e-07 1.3e-05 25.5 3.2 1 23 217 239 217 239 0.99

4 17 1.3e-05 0.00097 19.6 0.4 1 23 245 267 245 267 0.99

5 17 0.014 1.1 10.1 0.2 2 23 348 372 347 372 0.93

6 17 0.00032 0.024 15.3 0.2 2 23 398 420 397 420 0.96

7 17 0.064 4.8 8.0 0.7 1 23 492 514 492 514 0.97

8 17 0.076 5.7 7.8 0.3 2 23 522 543 521 543 0.91

9 17 0.021 1.6 9.5 1.2 3 23 554 576 551 576 0.86

10 17 3.5 2.6e+02 2.5 1.0 2 23 612 634 611 634 0.95

11 17 0.0026 0.2 12.4 1.1 1 23 678 701 678 701 0.97

12 17 0.0067 0.5 11.1 1.6 2 23 871 893 870 893 0.96

13 17 0.12 9 7.2 0.1 1 23 899 921 899 921 0.92

14 17 0.57 43 5.0 0.4 2 23 929 950 928 950 0.93

15 17 0.32 24 5.8 1.3 1 23 1055 1077 1055 1077 0.94

16 17 0.01 0.77 10.5 0.0 1 23 1087 1109 1087 1109 0.96

17 17 0.00023 0.017 15.7 1.2 1 23 1114 1136 1114 1136 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.0008	19.9	2.9	1	23	161	183	161	183	0.98
2	17	0.36	27	5.6	6.2	1	23	189	211	189	211	0.97
3	17	1.8e-07	1.3e-05	25.5	3.2	1	23	217	239	217	239	0.99
4	17	1.3e-05	0.00097	19.6	0.4	1	23	245	267	245	267	0.99
5	17	0.014	1.1	10.1	0.2	2	23	348	372	347	372	0.93
6	17	0.00032	0.024	15.3	0.2	2	23	398	420	397	420	0.96
7	17	0.064	4.8	8.0	0.7	1	23	492	514	492	514	0.97
8	17	0.076	5.7	7.8	0.3	2	23	522	543	521	543	0.91
9	17	0.021	1.6	9.5	1.2	3	23	554	576	551	576	0.86
10	17	3.5	2.6e+02	2.5	1.0	2	23	612	634	611	634	0.95
11	17	0.0026	0.2	12.4	1.1	1	23	678	701	678	701	0.97
12	17	0.0067	0.5	11.1	1.6	2	23	871	893	870	893	0.96
13	17	0.12	9	7.2	0.1	1	23	899	921	899	921	0.92
14	17	0.57	43	5.0	0.4	2	23	929	950	928	950	0.93
15	17	0.32	24	5.8	1.3	1	23	1055	1077	1055	1077	0.94
16	17	0.01	0.77	10.5	0.0	1	23	1087	1109	1087	1109	0.96
17	17	0.00023	0.017	15.7	1.2	1	23	1114	1136	1114	1136	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGCTGTATCGCGGTCCCAGTTCGCGTTtagagaatttaattgaaaagatTCAAGCGACCAAGGAGATAACCAATAACGATATGTACAGCACGCACACTTCGTCGAGCTACTCGCCCAGCATCTCGGATGGCACTTTGACGCCCAACtcacagttgcagcagccgcagcagcagcaggagcaacagcagcaggagcagcagcaacagtcccAGGCGAAGGCAAATGGCGATGCGGCAGAGCAAacggagctggagcaggagctgagCAAGCCGAAGCGACCGGCACATTtgcatcaccatcatcatcatcattatcatcatcagcaggCGCTGAAAATAGCGAACAAGCTGCGCAAAATCAATAAGGATGCAAAGCTGGCTGCAGGACAAGGACAAGGACATGGCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGaGCCACGCTGAGCATTTGCCTTTCAAGTGCGAGTACTGCGCGAAGCTCTTCAAGCACAAACGCTCGCGGGATCGCCATAAGAAACTGCATACAAATGAGCGGAACTACAAGTGTCCGCACTGCGAGGCTGCTTTCTCCAGAAGCGATCATCTGAAGATTCACATGAAGACGCACGACATCCAGAAGCCATTCCAGTGCAGCATGTGCAATCGTGGCTACAACACGGCCGCCGCCCTCACCTCCCACATGCAGAAGCACAAGAAGAACGCCGCCATCCTGGCCGCTGGCGGCAATCCCAATGCGCTCAACTACAGTCCACGCTCCACGGGTTCCGCCTCGATATCGAGCAATGGCAGCTTGCATAAGCGACGCTATGCCTTGGCTCTGGCCTCCGACAGTAGTCCCAGTCGCCTGGAGTTTCCCAAGAGGGCGCGTGGCCAGCTGACGACCACGCCCACGGCTAGTACaatagccacgcccacgcccacgccgctgctgcgctgcagctACTGCCCGAAGGCAACGGAGTTCAGCAGCCTCGAGCAGCTCAATGCGCATCTCCAGAGCAACcacgagcagcaacagcagcaccagcagcagcagcagcagtcgaagGATGCGGATGGCCAGACGAATGGCTTCCAGCTGAGCTGCGAGTATTGCACGATGAAGTTCGTCAATATCGCTGCGCTCTTCCAGCACATGAGAGTGACGCACTTGGATCGGCTGAGCAGTCCCAATTCCTATTACGAGCACTTCAATCGCCTCGGTTCGCCCCAGTCGAAGCTCAAATCGGATCTGGAGAAGTCGGAGAAGGCCGAGCAGGAGCTGCCCACGGATCTGAGCAGCAACAAGCGGCGTCCGCTGACATCGCCCACGCAGCAGGCGGCGGCAGCGCAGCCTCCTCCGCCGCCTCCTGCCCCGGGCATCTTCTTCTGCAATCAGTGCAACGCAGGCCTGCCGGACTTCGAGAGCTTTCGCAATCATCTGAAGAGTCATATCGCAGAGGGCATGCAGCTGATCTGCCCGCACTGCGGGCTCAGTCTGCCCGAGCAGTGCGAGTACGAACGCCACGTCGTCGCCCACTTTCTGATCAGCAGCTCCGAGTTCAactgctgcagcgccagctGTGGCAAGTCCTATGCCAAGGCCGAGGAACTGCATCAGCATCTGCTGGCCGAGCACGTCCAGACCATGCTCAAGTGTGTCCTCTGCTCGGAGCTCTGCGAGAATCGCATGGCCATGCAGCTCCATCTGGCCTGCGCCCACAGCCAGGAGTCGAAGCTGCTGCGATGCAGCGCCTGCCTGGAGCTCTTTCGCAACGATGCCGACTTCCATGTCCATGTGAAGACACGCCATCAGCTCCAGGGCAACCAGGGTTTGGGCAATCCCCCAGCTCCTGCCAATCCGCTCCAGTGCATGTTCTGTCGCGCCGTCTGCTCGTCGGAGCTGGAAATGCATTTCCATTTGGCGGCGCATGCGCGACAGTTCCGCTGTCCCAGCTGCCCGGAGACGTTCCATGTGGAGTTCCTGCTGGACAGGCATATGCAGAGCCAACATGGCGGCATCAAGGACAAGGAGTCGCCCGTCGCTGCCGGCATGGGCAGTTTGTATGTGAATGCGCTGCTCCCGCCTCTGgcagcggccgctgctgccgctgccgcagcaaccaatgccaacaataacaacaacaacaacaacaacaatagcaacctGCACATTGACTATAATGTCGCCTTCAAGGGTCTCTTTGGTGGTAATAATCCGCCGAGCAAGTTCTACAACAGCCCCCTGCAGGTGGACACCAAGCAGAGTCCGCATCCGGCCCTGATGTACGGCCTCAGTCAGCGCTACTTGATGGAGATGTACGCCGCCAAGGCCAACTCGCCAGCCAATGCCAGCGCCGCGGAGCTGCCCACGCCACAGGCCAACCAATCCGCGACAgcctcgagcagcagcaacaacagcttcaGCTGCGGAATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCCGAGCTCCACTCGCACCGGAAGCTCGCCCACAACCTGAAGACGGGCGTCAGCCTGCGCTGTGCCTATTGCTCCGGCAACTACAAGAGCCGTgcggagctggagcagcacaTGAAAAGCTGCCACAACTCGAGCGGGAAGCACAAGTGTCTCATCTGCGACGAGATCTTCCCCTCGCCGGCCATCCTGGCCGAGCACAAGCTTCAGCACTCCAAGGTGGGTCAGTCCGGCAAGTGCGCCCACTGtggccagcagctggagcatGTAGCTGCCTTCCGTGCCCACCTGGGCGAGCATGGCAACGATGGCAACCTGCCCATGGCCTGCATCTGCTGCCGCCAGACCCTGCACTCGGAATTCGAGCTCAGTCTGCATGCCAAGTTCCATACAAAGTCGCCCAGCTGCAATAGCCTGCAGGAGCCCGTCTGTGCCCTGTGCCTGGAGCCGCTGCCCGGCGCGGGGGAGACCGCCAAGCTGTGCGACAAGTGCTGTCGCAAGCACAATCTGAATGGCAAGCGCAAGGAGCAAGTGCAGCCAACGGCAATCGCTGCTCCAgcggccgcagctgctgccgttgccgtcgcagTCGCGGCGAGCGCCTACCTGGAGCATCGCTGTAATCTCTGCAAAATGATCTTGCCCCATGCCCAGAAGCTGCAGGAGCATCTCGTCGAGCACACCTTCGCCGGCACCGAGCAGCGCGGCTTCAATTGCTACATCTGCTCGGCTGTCTTCACAGCGCCCGGTGGGCTGCTCGCCCACATGGCGGAGCACGGCACGCGTCCTTACGATTGCAACTTGTGCCCGGAGAAGTTCTACTTTCGTGCTGAGCTGGAGCATCATCAGCGAGCGCACGAGCTGCACCCACAACCAGCTGCATCCACAGCACGTCCTCCCAAACAGGAGACGCACAGCTCGACGGCCAGTTCACCTCTGACGCTCAGTCCCAGCCACGTCAAACAGGAGCTCTACGAATCGGAGCCAGCGAATTCACCCAACGGCGTTGAGCTGCCCGCGCAGccggaggaggaggagtaCATCGAAGTGGAGCAAGTGCCACAGGAGACGCTGCGAACGGGCGAACTGCTGAGCACCGAacgctccagcagcagcgcctaA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQLQQPQQQQEQQQQEQQQQSQAKANGDAAEQTELEQELSKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGQLTTTPTASTIATPTPTPLLRCSYCPKATEFSSLEQLNAHLQSNHEQQQQHQQQQQQSKDADGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNSYYEHFNRLGSPQSKLKSDLEKSEKAEQELPTDLSSNKRRPLTSPTQQAAAAQPPPPPPAPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQCEYERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCVLCSELCENRMAMQLHLACAHSQESKLLRCSACLELFRNDADFHVHVKTRHQLQGNQGLGNPPAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPVAAGMGSLYVNALLPPLAAAAAAAAAATNANNNNNNNNNNSNLHIDYNVAFKGLFGGNNPPSKFYNSPLQVDTKQSPHPALMYGLSQRYLMEMYAAKANSPANASAAELPTPQANQSATASSSSNNSFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCNSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRKEQVQPTAIAAPAAAAAAVAVAVAASAYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLAHMAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELHPQPAASTARPPKQETHSSTASSPLTLSPSHVKQELYESEPANSPNGVELPAQPEEEEYIEVEQVPQETLRTGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00502755;
80% Identity: -