Basic Information

Insect: Drosophila melanosoma
Gene Symbol: -
Assembly: GCA_035042045.1
Location: JAWNLY010000201.1:3685579-3689292[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.054 3.7 8.1 0.1 2 23 186 208 185 208 0.96

2 9 2.9 2e+02 2.7 1.7 2 21 796 817 796 819 0.89

3 9 9.2 6.3e+02 1.1 2.4 3 20 831 849 829 853 0.90

4 9 1.5e-06 0.0001 22.5 2.8 1 23 889 911 889 911 0.98

5 9 0.00069 0.047 14.1 3.6 1 21 935 955 935 956 0.94

6 9 2.8e-05 0.0019 18.4 4.2 2 23 963 984 963 984 0.98

7 9 0.021 1.4 9.4 3.3 1 23 990 1012 990 1012 0.98

8 9 0.012 0.79 10.2 0.8 1 23 1018 1041 1018 1041 0.97

9 9 0.029 2 9.0 0.3 1 23 1051 1073 1051 1073 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.054	3.7	8.1	0.1	2	23	186	208	185	208	0.96
2	9	2.9	2e+02	2.7	1.7	2	21	796	817	796	819	0.89
3	9	9.2	6.3e+02	1.1	2.4	3	20	831	849	829	853	0.90
4	9	1.5e-06	0.0001	22.5	2.8	1	23	889	911	889	911	0.98
5	9	0.00069	0.047	14.1	3.6	1	21	935	955	935	956	0.94
6	9	2.8e-05	0.0019	18.4	4.2	2	23	963	984	963	984	0.98
7	9	0.021	1.4	9.4	3.3	1	23	990	1012	990	1012	0.98
8	9	0.012	0.79	10.2	0.8	1	23	1018	1041	1018	1041	0.97
9	9	0.029	2	9.0	0.3	1	23	1051	1073	1051	1073	0.98

Sequence Information

Coding Sequence: ATGCATTGCAACATGAACGATGTGGCGGATGCAGCCTTCTCCAGTTTCTACGTTGGCAGTCAGctACAGCATGCGGAGCTGTCGCTATCGACGCCCATCCATGCCCTGGAGCACGACAGCAATTTCACCGGACTCTTTGACGATGATCCCGCCCTGCTCTCGCTTCCCCTAACGACAATAACGGGAGCAGCTGTGCATAAAGTTGCATCGAGCGTTGCAACGGAGACCGCCTGCATTCCGTTTGTACAGATTCATACGACAgatctgcagcagcaactcgaACCAGGTCGTAGTTATCGCAATGGATTTCGACGACGCACAGCTGAAATCAAATCGGAGGCTGAACTCATTAAATCAGAGCAGGCAGAGGCGGCGGCTAAGGAGCGCATCAATGCAACGCCCACGCCGCCCACAGCTACAAAGACGATAACGAGCGAGGGTTGCTCGGATCTGCCGCTGCACAAATGTCCCAGCTGCCCGTTCCTCAGCCTCTGCCAGCTAAAGGCCCAAACGCAcatcagcagctgctttgGCGTCGATGCTCAGCGTCGCCTGCAGTGTCCAGGTTGCACGAATATTTTCTACAGCATCGATGTGCTGCAGCTACATCTGAGCACTGATCATCAGCTGGAGTCACAGGAGATAGCCAAGCTGACGGGCAAAACCAACGAAAGACCAGCCAaaaaaccacagcagcaattgctgcCAAAAAGTCGGATCTTTATCAAGAATGTGGATTGCTTGAGGGAGCCACATCGCGAGCAGGATACAATCAATCCATTTTCCGACTTTTTGCCGCTGTTGCCCAACTCGCCAGATGGCAGCACTGGCAATATACTAGATCTGCTTGATGATGTTgacgaggagcagcagcagcagcagcaacagcagcaaatctTGCCAATGATCCAAAAGCCAGCCGTGCAAAAGATATCCATAAAGAGTGTTGATGTGCTGCGGGAGCCGGCGCTGCTCCCCTTTGACTTCCATCTGCCCAATGCCGgagagcaactgcaacagcagcagcatcagttgcCGTTGCCTCCACTGCCAACCCTGTTGATGGGCAACAATTTGCTAGATGTGCAGGAAAAGCCGCGTCAGCCGAAAATCTATATACGCAATGTGGACATATTAAAGGAGCCCATGTTGCTGCCGGGCATGGGCTTCAACGAGGCACCCACCACATCGACAATCGAGGGTCCCGTGGAGATATTTCCCGCCGAAACGCTACTAACGCCAACCGGTCCAGTGGGTCCACTGCCCGGCTTTGAGCCAGCTCTGGCCCCACTGGTCAACATGTGCGGGGAGTCGTTCAATTTTGATGCCGTGCTTAGTGGTGCTGGCACCACCAGCAATAACAGTGTCAGCAGTAACAATTTCAGCGCCttggatttggattttggTGTGGATTTCGATAACAATGTGCAACTGGAGAcgacaccaccaccaccagcaccaccgcCATCAGCAGCACCATCTGGAGCAGCAGTATCAGCGGGACCAACAGAAGAACCATCTTCACAGCAGTCACTTATAAGCGCGCAGCTGGCAGAGCTCGGCGCACTGCCTCAAGATGAGCTGGAGAACTACTTGCCAAGGACGACATTGTCGAAGCAAAAGATCTTCATCAAGAATGTGGACATATTGAAGGCACCACAACGTGGTACTTTGCATCTGCGCACCGTTGACGAACTGAATCTGATGAATCGTAACGAGGTGGAGCATCTAATTGTGCCACATAGGGACCcgctgcagctggagcagctgccACTAAATGCCACAggtgctgctactgctgctgtcacACTGGAATCGACACTTGTCGATTTCGAACAGGCCCCATCAGCGCCATTGAGCTATGATGATAGCTACGATTTGGCCGAGAATCTAGAAATCTGGCCTTGGATGGAGGAATCGGTGCCAGAGGGCATCGTTACAGCCTCAGAGATGGAGCACGATGTTACGGAGCAGTTAGAGTTGCCAGAGATTGCCGACGATATTTTGATTAAGGATTTCCCGCAACTCTATGCCCAGCAGACGCCCACAGCGGATGCTGTGCCGCCCTTGGTGCCGGTCACTGGCTCACCAGAGCTGACGGCGACCTCAGCTGTGCCGACAGAGAACTTGTGTGGGTTACCCGTGCCGCCACTGGTACCGCTCGCTGCAGaggcggctgttgctgctgcctctactgctgctgtcggCGCCGATGAAAAGCCCGCACGCATTTATGTGGCCAACAATTTGCTCCCCGCTGCTGTGGAGCGAGCCCCGCTGCCTGGTGGCACGTCGGTGCGTGGCCGCCCATATGGTGCCAAGCAGGCGGGTCAGACCGCCAAACGGCGGCCTGCACAGACCGCAGTCCAGTCACTCGAAGGTGGCAAATGCACCGTGGAGGGTTGCATGTTCCGCTTCAAGTCACCGAGCACCTTGGAGTACCATGGACGTTGTCACAATGGCTCGCTCGGCTCCACACAGCCGATGATCTGTCCCGAGTGTAGATCGACGCAGTTTAGCAATTGGAATTGCCTGCACACCCATCTCTGGCGCACCCATGAAATCGACATGGAACTGTACTGCTGCCAGCTGTGCAGCTTTAAGACGCCCATTTACTCGAGACTGGTGAACACCCATTCCAAGATCCACTCCGAGGAGCGCAACTACAAGTGCGAGCAATGCGGCAAGGGATTCAAGAATACCAAACAGCTAAAGAATCATCGACGATTGCATCGCACCCAAGGACTAGGTATGTCAGCCAAGCCAAGCATTAGCGAGGAGCAGATAGCGTTGCCCACATTGCATCGCTGCGAGGATTGCGGTGCCGCCTTCAAGCATCGCAAAACGCTGCGGGAGCATCTGTGCAAGCAGCGCAATGAGCAGCCACAATGCAGCACCTGTCAGCGCGTCTTTAGCTCGAAGAGCAGCCTCAAGTTGCACATGCACAGTCATCAGGAGATCAAGCGCTTCAAGTGCGACAAGTGCGATCATGAGGCAAATGATCACAATGCCTTCCGGCGTCATCTGGCCACTCATCGGGAGGCCAAACGCTATGCGTGTCCACATTGCGATTTTAAGGCCATACAAAGCACAGCCTATCGAATACACCTGCAGAAAATGCATCAGGAACAGGAGCTGTCAACCATCATATACAAATGCAATGCATGCACCTTTTCCAGCATCAATCGCGGCCTGCTGCTGGTTCACCAGGCCAAGCACGACACAGCGCAAAGCGAGTCCTCAAAGATCAAAGTAAAAAGTAACCTCCTGCTTGCCCCAAAAGTTATGGAGCCCAATCAGGCAGAGTTGGTGGCACTTGCGGCGCCAGCAGGCGATTCAATTGCCTAG
Protein Sequence: MHCNMNDVADAAFSSFYVGSQLQHAELSLSTPIHALEHDSNFTGLFDDDPALLSLPLTTITGAAVHKVASSVATETACIPFVQIHTTDLQQQLEPGRSYRNGFRRRTAEIKSEAELIKSEQAEAAAKERINATPTPPTATKTITSEGCSDLPLHKCPSCPFLSLCQLKAQTHISSCFGVDAQRRLQCPGCTNIFYSIDVLQLHLSTDHQLESQEIAKLTGKTNERPAKKPQQQLLPKSRIFIKNVDCLREPHREQDTINPFSDFLPLLPNSPDGSTGNILDLLDDVDEEQQQQQQQQQILPMIQKPAVQKISIKSVDVLREPALLPFDFHLPNAGEQLQQQQHQLPLPPLPTLLMGNNLLDVQEKPRQPKIYIRNVDILKEPMLLPGMGFNEAPTTSTIEGPVEIFPAETLLTPTGPVGPLPGFEPALAPLVNMCGESFNFDAVLSGAGTTSNNSVSSNNFSALDLDFGVDFDNNVQLETTPPPPAPPPSAAPSGAAVSAGPTEEPSSQQSLISAQLAELGALPQDELENYLPRTTLSKQKIFIKNVDILKAPQRGTLHLRTVDELNLMNRNEVEHLIVPHRDPLQLEQLPLNATGAATAAVTLESTLVDFEQAPSAPLSYDDSYDLAENLEIWPWMEESVPEGIVTASEMEHDVTEQLELPEIADDILIKDFPQLYAQQTPTADAVPPLVPVTGSPELTATSAVPTENLCGLPVPPLVPLAAEAAVAAASTAAVGADEKPARIYVANNLLPAAVERAPLPGGTSVRGRPYGAKQAGQTAKRRPAQTAVQSLEGGKCTVEGCMFRFKSPSTLEYHGRCHNGSLGSTQPMICPECRSTQFSNWNCLHTHLWRTHEIDMELYCCQLCSFKTPIYSRLVNTHSKIHSEERNYKCEQCGKGFKNTKQLKNHRRLHRTQGLGMSAKPSISEEQIALPTLHRCEDCGAAFKHRKTLREHLCKQRNEQPQCSTCQRVFSSKSSLKLHMHSHQEIKRFKCDKCDHEANDHNAFRRHLATHREAKRYACPHCDFKAIQSTAYRIHLQKMHQEQELSTIIYKCNACTFSSINRGLLLVHQAKHDTAQSESSKIKVKSNLLLAPKVMEPNQAELVALAAPAGDSIA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00522548;
90% Identity: iTF_00499210;
80% Identity: -