Basic Information

Gene Symbol
-
Assembly
GCA_035042045.1
Location
JAWNLY010000188.1:1419334-1428237[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.00084 0.058 13.8 2.0 1 23 861 883 861 883 0.98
2 8 0.00022 0.015 15.6 1.3 1 23 915 937 915 937 0.97
3 8 1.2 85 3.8 0.4 1 19 944 961 944 967 0.85
4 8 0.0033 0.23 11.9 0.0 3 23 974 995 973 995 0.96
5 8 0.00015 0.011 16.1 1.7 1 23 1001 1023 1001 1023 0.97
6 8 0.025 1.7 9.1 0.2 1 23 1030 1053 1030 1053 0.95
7 8 0.00035 0.024 15.0 2.2 2 20 1060 1078 1059 1081 0.91
8 8 0.26 18 6.0 10.7 1 23 1087 1110 1087 1110 0.96

Sequence Information

Coding Sequence
ATGGAAGAACCGGTGGATCAGTCAGTGAATCTACTGGACAGTCTGAACGCTGCGTCGCGGTGCGATGCAATTAAGTTTTTGCTGCAAACGCTTAAGTGCAAATATCCAGAGGCCTGCGACAGAGTCGTCAGGAGTCTGTACATTAACAGTAGTCACAGTAAGCCGACGACTGACAATGGCGCCGGTgcggaggtggaggaggagcaaAAGGAGAAGGACGGAGTGCAGCTAGCGAAGAGAGatcagttgcagctgctgcttgctgccacCGCCATGAAGAAGGAGAAGACGGAACCGGGCACAGGAATCGGGGTTGTGAAAATCAAGCTAGAGAACGAGGATGAAGCATCCGCGATCGATTTAAATCAAAACTTTGAGAAAATTCTCTGCAAGGAGGAGTTTATGTGCCTCGACGAGGAGGATGATTTCCTCGATAATGATGTGGCCGATGCTGATGCGGATGTCGATTTGGATGCGGATGTTGACACAGAAGAGAACTCATCTTCCATTGGCAAACATGGACTGCATCACTATCATCGCAACAACAATGTTAATGTCGGAATTGCCGGACGACGCGTTGCCGGACACGGTGTGCTGCTCACCAGTGCTGATCCACTCGATCTAATACACACGGTGAAGCGACGCTATGCGGCGACATTCGCCGAAGATGATGACGGAGACGATGATGAAGAGGAGGGGCAGGACGAAGAACAGGCGGAGGAGCAGGCGGTGGATGAGCTGCTCTCaatgcaacggcaacaaaagcTGGCGAAACGAAAGCGAAACAACAATCACATTAGCAACAGtagctacagcaacagcagcaatatcaTCTCACCATCTGTCCATCTGCTGTCCACACGTTCTGCACGTCTAGGCGATGGCTATGTGTTCCACGAGGACAACCAGTACACGTTGCGCTATCATCACAGCAGCGGCGAGTTCAGTGAGCGGGCATTCAAGGCACAGTTTCGTCTGCTGTTGCGACTGGCGCTGAGTCAACATCACAAGCCGTTCCTTAAGCAGTTCTATGAGAATTTTGTGATCACCGGCCGGCTGCTGGGCACCACGCCCTCGACACGGGTGCTAAAGGAGCTGCGAGAGCAGCGGCTGGCTGAATGGCGACTGCAAAGCGAACGCAAACTGTTAGCGAAAACTgttgccgccgcagcagcagctgcagcagcggcagaggaagcggcagcagcagcagcagcaaaggaaGCGgcggcagtagcagcaacagttgctgcccGGCTAGCGAAGGAACAGCagaaggagcaacagcagcagcagcagcagcagctggagctggagctggaaaagcagaagcagttccagcatcaggagcagcagcagcagttggaacAGCAattggatgtggatgtgtCCCCGTTGCAACTGCAGCCAGAGCATCAGCTGAGATCCATTTCGTTTGGTGACTCGGAGCTGGAGTCGGAAACGGAATCACAGCTATCGTCGACGGCGCAGGAGATTATGAAGTTTGAGGAGTTCATTGATGATGGTGTAGGCGCAGGTCGTCTCATCGATGGGCTCGAAATGGAGCCAGAAATAGATGAGATGATGCTGGCTGGTGCCGGTGGCAGCGCCGGCGACGTTGGTGACGGCTGCGGCAGTGGATTGGGCAGCGTAACGGGCACCTGCAGCGGCAGTGgaaacagcaatagcaacagcagcgccgtTCACGACAACGGCATCGCCTCCCTCCTCATGGACACCAGCCATGGGCAGCAGCTTCATTCGCACCATCTcagcagcaacagcagcagtagtggTGGAAATCTTGTGATCAATGGCCTTACGTCAAGCAATAtgcacagcaacaatattaattgtaaCAAGAGCAATAATGCGCTCAattcacagcagcagctggcgccTGACCATCCCTCGAAGCAGTCCGGGCCGCATCAGGTTCGGGATCGGGAGCATCAGGCGCAGATGCAGTCGCAATCGCAACAGTTATCGATGCCACCAATGAGAAGCGGATATGGCATTGATGGCGTTGCGATGTCGGCGACAACGCAGCTAATGGCTGGCACTGAGATTCAGCTGCAGAACGAGTCGCAAAACCAGACGCAGAATCAGAACCAGAACCATTATAATTCAAGCAATAATCCGCTCTCGATGCCGCCAATCATTGAGCAAAtgatgcaaatgcaaatgcatcagcagcaacagagacCATTTCCCCAGCATCAGCATGCCCAACTGATGAACAACCGTCAGTCGCATCTGCATCCGCATCCCCATCctcatccccatccccatccgcATCCCCAGTCACATCCACATTCGCAGTCGCAGCCAACGACGCATTTGGGTGCAGCGAGTGGTATTGGAGGATCATCGCAGCTGAACTCATCGCTAGAGCTGGACGACAATGAATTGTCGGGCGAGGAGGATGACGATGACCTAGACAATGAGATTGACGAGCTGGACGCGGCCAAGCAGCAGCTCATTgatggcggcagcagcagcagcacctccCTGCAAGCGCCACCCTCCCAGCTCGGCGGCAGCCATACGCCCGGCGGCAGTAAAAAGGACAAGCCCAGCTACAATTGTCTGCTGTGCCCCAAGTCGTACCGGAAGCGCAAATCGCTGCTGGACCACTACAAGATGCATCCCGGCTACTGTCACGACTGTGGCCAGCCCAATGGCAACACCCTGGAGgAGATAATTCAACACAATCGGACGATGCATGTGAAGGAGTTTCCGTTTGTGTGCGAGACCTGCGGTGAATCCTATTCACGTCGACAGCAGTTCCATGCCCATGTGGAGTCGCACAAGAAGGATTTCAAAATCTTCCCGTGCGGCGAGTGCGGCCTGAAGTTGTCGCAGAAGAAGTTGCAGCAGCACTTTGAGGAGACCGGCCACAAGGCCGATGGCGCCATCTGCGAGGTTTGCGGCGCCGAATTTCCATCGAAGAATGCCCTCTATCAACACATCATACGGGTGCACAAGCGTGACAATTTCTTTGAGTGCCACATTTGCCAGAATCGTTTCACACTCAAGGCCAATCTGGAGCGGCATGTGCAGCTGCACACGGAGGTGAAGCGCACGTATGTGTGCGATATGTGCGGCTCCTCCTATTTTACATATCCCGCACTCAAGGAGCACTACAGCAACGCCCATGTCGATGTCTCCGAGTGCAAGTGCACCCTTTGTGGCAAGAGATTCGGTTCGGCCAAATCTCTGCAACGCCATTTGCCATCGCACTCTGAGGAGCGGCCGCATTGCTGCAATCACTGCGATCAGaCTTTCAAGTGGAAGACGCATTTGGTGCGCCATAAACAGACGATGCATGGAAATCAGCCGCCGCCACCCAAAAAGGGCAAACAGCGTTTCCCCAAGGCCAACGAAGAGGATATGTTGCCACTGCCTGATATGCCGGGGCCGCCGCCGGTGAAGGCTAGTAAAAAGTCGGCGGTCAGCAAGGCAAAGACACAAGCAGgtgcggcagctgcagccacacagcagcaacaacagcaacaacaacagcagcagatgcagTCGGGAGTTGGGAAGGGTGGTAGTGTGggagccacgcccacaccgcCCCCACCATTGTCGACGACGCCTGGCTGCTCGCAGCAGGACCCGTTCAATGCCGCCATTGTGAGCAGCAACAGTTCGCAATCATCGACGGCATCCACGTCACAGCACTCGGTCTCCACGAGCGAATCTCAGCAAAATTCCATGTACAATCAGAGCTTTAGTGCCGAtaagttgcaacagcagcagcagcagcctccggcgcagcaacaacaacagcagcagcagcagaatgcgttgcatcatcaacagcagcagcagcaacatgcggCAGCAACGCCACCACCAacgccacagcaacaacaacagcaagcgtTGCCAactgcacagcagcaacagcagcagccgccgcatcATCGCCATACTCCACACACACCGCATACACCGCATACGCCGAACAACAGCACGCCGGAAATGCATCTGCAGCGAATGAACAGTTTTGGCGGGCCGGAGAGCCAGTTTCACTTCGAGCCCACCGGCAATCCAGCTGTCGGTTATCAGCAACATCAGGTCTTAAATCAgtatcaacagcaacagcaacaacagcagcaggcgcaacaacaacagcagccgccacagccaccgcagcaacagcagcagcagcatatgcGCAGCCACACGCCACAGagtccacatccacatccacatccacatgcGCATCCGCATCAGgcacagcagttgcaacagccgcagcagcagcaacactttaGCTCGCCGCATCACATGCCACCAatgcatcatcagcatcagttgctgttgcagcagcatcgTCACAGTCATTCGccgcaacatcagcaacactCGCGTTTGCAATctccacagccacagccgTCGCCATCGGCCGCTGCTTCAGCAACACAACAGCAAtttttgcaacagcagcagcaacaacaacaacaacaagcgactGACTCATGGGGCAACATGGGCTTTGGTGGCGCACCAAACACGCAACCGGTCGAGCTGAAGGACAACAAGTTCTACATTGTCGACTCGACCGAGTTTCTCGGGCTTCCAATGAACGTGGGCACACCAACGCCACCCACTCAACAGCAagccgctgttgttgtcggcaacaagccgcagcagcagcaacaggcgccACAAGATCCCGCCTTAGCTGGCGATCTATTGGGCTTCCAGCACATGTggccgcagcaacagccgcaaccgcaacagcagcagcaacaacaacagcagcagccggcaacagcagcgccgcAGGTGAATCAAGTGGGGCAGGGAGATGCACACAACTACAATAATATTGGTAGCATTCTGACGAATCTCATCGACACAAATCCCACGCCTTTGGAGTACAACTTTGATTTAATGCCacaatcgcagcagcagcaacagcaatcccagcagcagcagcaaccactgCAGTCGCAGCAACATCAGGCGGGTCAGCAACATCacaatgcagctgctgcttacGGTGCCGGCCTTATGCGGCACGGAGTTCCAACGGGCAACGTTTACtacgagcagcaacagcatcacaATCACAACCACAGTGCGCTgagcgagcagcagcagcagcagctagtCAGCGAACAGCAGAAGCACAATAGCTTCCAGCCATATCATCCACACgcgcatccacatccgcatccacatccgcatccgcatggactgcaacagcagccgttgCATTCGTTGGCGGGCGCCTCACATTtgttgccaccaccaccgccgcatGGCAGCGTCTATGAGCGTACAGCACCACCAGTGGGTGTCGGTGGTTATCCCATGCTCGGCGATGATAGCAAGTCTGTGTTGCCGCCAATCAATGACTATATGCATCatatgcagcaacagcagcccgATCTAATCTACTATCCAGTGAAAAACGATTGA
Protein Sequence
MEEPVDQSVNLLDSLNAASRCDAIKFLLQTLKCKYPEACDRVVRSLYINSSHSKPTTDNGAGAEVEEEQKEKDGVQLAKRDQLQLLLAATAMKKEKTEPGTGIGVVKIKLENEDEASAIDLNQNFEKILCKEEFMCLDEEDDFLDNDVADADADVDLDADVDTEENSSSIGKHGLHHYHRNNNVNVGIAGRRVAGHGVLLTSADPLDLIHTVKRRYAATFAEDDDGDDDEEEGQDEEQAEEQAVDELLSMQRQQKLAKRKRNNNHISNSSYSNSSNIISPSVHLLSTRSARLGDGYVFHEDNQYTLRYHHSSGEFSERAFKAQFRLLLRLALSQHHKPFLKQFYENFVITGRLLGTTPSTRVLKELREQRLAEWRLQSERKLLAKTVAAAAAAAAAAEEAAAAAAAKEAAAVAATVAARLAKEQQKEQQQQQQQQLELELEKQKQFQHQEQQQQLEQQLDVDVSPLQLQPEHQLRSISFGDSELESETESQLSSTAQEIMKFEEFIDDGVGAGRLIDGLEMEPEIDEMMLAGAGGSAGDVGDGCGSGLGSVTGTCSGSGNSNSNSSAVHDNGIASLLMDTSHGQQLHSHHLSSNSSSSGGNLVINGLTSSNMHSNNINCNKSNNALNSQQQLAPDHPSKQSGPHQVRDREHQAQMQSQSQQLSMPPMRSGYGIDGVAMSATTQLMAGTEIQLQNESQNQTQNQNQNHYNSSNNPLSMPPIIEQMMQMQMHQQQQRPFPQHQHAQLMNNRQSHLHPHPHPHPHPHPHPQSHPHSQSQPTTHLGAASGIGGSSQLNSSLELDDNELSGEEDDDDLDNEIDELDAAKQQLIDGGSSSSTSLQAPPSQLGGSHTPGGSKKDKPSYNCLLCPKSYRKRKSLLDHYKMHPGYCHDCGQPNGNTLEEIIQHNRTMHVKEFPFVCETCGESYSRRQQFHAHVESHKKDFKIFPCGECGLKLSQKKLQQHFEETGHKADGAICEVCGAEFPSKNALYQHIIRVHKRDNFFECHICQNRFTLKANLERHVQLHTEVKRTYVCDMCGSSYFTYPALKEHYSNAHVDVSECKCTLCGKRFGSAKSLQRHLPSHSEERPHCCNHCDQTFKWKTHLVRHKQTMHGNQPPPPKKGKQRFPKANEEDMLPLPDMPGPPPVKASKKSAVSKAKTQAGAAAAATQQQQQQQQQQQMQSGVGKGGSVGATPTPPPPLSTTPGCSQQDPFNAAIVSSNSSQSSTASTSQHSVSTSESQQNSMYNQSFSADKLQQQQQQPPAQQQQQQQQQNALHHQQQQQQHAAATPPPTPQQQQQQALPTAQQQQQQPPHHRHTPHTPHTPHTPNNSTPEMHLQRMNSFGGPESQFHFEPTGNPAVGYQQHQVLNQYQQQQQQQQQAQQQQQPPQPPQQQQQQHMRSHTPQSPHPHPHPHAHPHQAQQLQQPQQQQHFSSPHHMPPMHHQHQLLLQQHRHSHSPQHQQHSRLQSPQPQPSPSAAASATQQQFLQQQQQQQQQQATDSWGNMGFGGAPNTQPVELKDNKFYIVDSTEFLGLPMNVGTPTPPTQQQAAVVVGNKPQQQQQAPQDPALAGDLLGFQHMWPQQQPQPQQQQQQQQQQPATAAPQVNQVGQGDAHNYNNIGSILTNLIDTNPTPLEYNFDLMPQSQQQQQQSQQQQQPLQSQQHQAGQQHHNAAAAYGAGLMRHGVPTGNVYYEQQQHHNHNHSALSEQQQQQLVSEQQKHNSFQPYHPHAHPHPHPHPHPHGLQQQPLHSLAGASHLLPPPPPHGSVYERTAPPVGVGGYPMLGDDSKSVLPPINDYMHHMQQQQPDLIYYPVKND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00482605;
90% Identity
iTF_00597770;
80% Identity
-