Basic Information

Insect: Drosophila melanosoma
Gene Symbol: -
Assembly: GCA_035042045.1
Location: JAWNLY010000086.1:1083958-1114129[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0057 0.39 11.2 0.6 1 23 1259 1282 1259 1282 0.96

2 8 0.5 34 5.1 1.0 1 23 1287 1310 1287 1310 0.96

3 8 0.0002 0.013 15.8 0.8 1 23 1526 1549 1526 1549 0.96

4 8 0.0028 0.19 12.2 0.8 2 23 1558 1579 1557 1579 0.97

5 8 0.044 3 8.4 0.3 1 23 1586 1609 1586 1609 0.96

6 8 1.7e-05 0.0012 19.1 1.4 1 23 1615 1637 1615 1637 0.97

7 8 8.6e-06 0.00059 20.1 0.4 1 23 1642 1664 1642 1664 0.99

8 8 0.0013 0.088 13.2 4.2 1 23 1670 1692 1670 1692 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0057	0.39	11.2	0.6	1	23	1259	1282	1259	1282	0.96
2	8	0.5	34	5.1	1.0	1	23	1287	1310	1287	1310	0.96
3	8	0.0002	0.013	15.8	0.8	1	23	1526	1549	1526	1549	0.96
4	8	0.0028	0.19	12.2	0.8	2	23	1558	1579	1557	1579	0.97
5	8	0.044	3	8.4	0.3	1	23	1586	1609	1586	1609	0.96
6	8	1.7e-05	0.0012	19.1	1.4	1	23	1615	1637	1615	1637	0.97
7	8	8.6e-06	0.00059	20.1	0.4	1	23	1642	1664	1642	1664	0.99
8	8	0.0013	0.088	13.2	4.2	1	23	1670	1692	1670	1692	0.99

Sequence Information

Coding Sequence: atGAGTGCCAATAAGCGACGAcgctgcaacagcaataacagcagcacaGCTGATCAAATTGATAAGCAAGTACAGAGCAAAGAATGCAAAGAAATGCCAACAATTGATGTACAACGCTTGTGTCGCTGCTGTGGCAAAGGCGACATAGAATTACTCAAACTGTTCGAGGAGAGCGCTACGACTGCCAATCAGAAGACACAAACTCAAATTGCGATTGCGCAAGTTCGCCAACGCCAAACGACGACAGCAGGCGAAACAGAGGGAACagcacaacaagaacaagaacaacagcaagaacaaaaacagcagcagcagcgcaaaaGTGATAATCCTGTGGAATATGCGCTGAGTGGAGCACACAGCAGCATGGACATTGTGTTAGAAGAGATGAACATATGGACGCTCAATATCTCACGCGACGATGGTCTGCCTCAGGAGATTTGTCGCCAGTGCAAGGCGCAATTCATAATGGTTGCGAAATTTCGGCGGCGATGCATTCGCGTCCAGCAGCGACTACAAGACTACAACCAGGACATGACCAAGAGCAGTTcacagaagaagaaggagcAGCGCACACAGCAGTCACAGACAAAGCCACAGGCAAATGAGGCATCCGCGGCAGATTACATGCATCTGCCACAGTCAGTAAAGGAGCGGAAACGTCGCCTAGTGCCAAACACGGAGACGTCGGCGCTGCCAAAATATGCCAAGACTGATGACACACAGCTGCTGATGACGCCCAAGCAGCGGCGGATACAGTTGGGGGTGTGCACTACGCGCTGTAACTCCTTGCCTGCCTGTAAATTTGAGACTGAAACGGAAACGAAAGTGGGAGCCGGACCGGAAGCGGGAGCGGGAGCGAGAGCCACAGAAACAACCGGCGACTATCGACTGAGTGAGACGAAGCCTCGAACGCCACAGAGATCGCCATATAGAGCCAGACTTATACACGTGCCATGGAGAACGAAAGCGGCACGCAAACAGATCACGGAAATGCGGTCCACTGACTCTGAGCAGGAGTCAGCTAAGGCTATGGCAACGACTACTTTAATGATAAAAACAGCCGATGCGAGTGCAAATTCATCGGAAGATTTGAGTGACTTGTCGGTGAGTGCATGTCAAGGCTTTGACAACGGGTGCAGCAGCTCCAACTCCTCCCCAAAGTCAACTACCAATTCGAAGCTCAGGTTTCCACCAAAACGCTGCTCGCCCATTAAAGCACGTGTTTTGCGGCGACTGGAGAGATGCAATTATGCACCGTTCAAAAGGACGAGGCGCGTTTTCAAGAAGGCAACGGCGAGAAGTGAAGCACCTAAGCAGGAGCTGAGCTGCGTAGAGATGCCAAGCACTGAAGCAACGAAGGAAACACAGACAATTgatcaaataacaaacaactcTGCGAATGAGGAGACGACCAGCagccggagcagcagcagcagtagttcGCTAGAAACCCCTGAGATGATCGATGAGGAAGCACAGAATGGGATGCCAGAAATGGAGTCAAATGTGCAGCAGCAAGAGATTAGCATAGTCGATGAGAAAGCACAGAATGGGATGCCAGAAATAGAATCAAGTGCTCAGCAGGAAGACGCACACATCGAAAATACAAAGGAAGAGCTGCAGCCCGATGAGGCAATCAAATCTGCGCCAGAAACTCAGCACATAAAGTTGATGGCACAAATGGAAAGCATATCAGAAGAAGTGATAAAGACGGATGGGGCAGTAAATGGAACAGTAGAGGCAACGCTAATGAGTCCTGTGCAGCTAGAAGAACTAAGCTCTTCCAGCACGGGTCACATGGAGGGAGAGAGACGTCAATCAGCAACGCCCGAGTTGCCAGCTGCAGAATACGAGGTGGAAGTGAGCCTAACCAATGAGGAGCAAACTTCGGACCAAATGTCAGAGCAATTGTCGGAGCAATTGTCGGATCAAATGTCGGAGCAGATGTCGGAGCAAACGTCGGAGCAAATGTCGGATCAGATGTCGAATCAGATGTCGAATCAGTTGTCGAATCAGTTGTCGGAGCAAACGTCGAATCAGACATCGGATCAGATGTCGGAGCAAACGTTGGAGCTTATAGTCAATATACCGCTAGATGCGCTTGGCCAGAAACTGCAACGTAAATTGTGCAACGAGTCGGAGACATCGACAAATGACGAGTTGGAGCAACCAGCTGGCGTGGAGCGCAAGGAGCCCGCCGAGTCGGACGATGTGAATAACAATGAGAAAAGCGAGCATTTTTACCAGAGTGCTATAGCAGATAGCTTCAATGCTGCTGTAGCACTCGCAACCAAACAAATTGAGGCAGAACCCGGAGGTgacgatgatgttgatgttgatgttgatgatgatgatgatgatatggAGTCACTGGAGAAACTACCCAATCTGCagcacgagcagcagcagcagcagcagcaacaacagccacgcACATCTGCCAGTTCCATGGATTTCTTGGCTGAATTCGAGAAGCATTGCGAAAAATCGATTAAGCTGCAGGCAGCTGGGCAAGAGCTGGCGGAGGCCAAGCAACAGTTGGCGGTGGAAATGAACTATGTTGCGAATACCCTGCACGGCATACTCAATGAGATGCAGGATGAGCATCTCTACACGCCCGTCTGCACGCCCATCGATGAGTTTCTCACGCCCGCCGATTATGCGCCGCCCACGCCAGCCTCGCCCAATCTCTATGAGCAGCCCGTGgaggcacagcagcagcagcaacaacagcagcagcaacaacagcaacaacaacagcaacatcaaaaggAGGGAAATCTCTTTGACAGCAGCACTTTTAGTAATGAGATGATTGGCTTTCAAAATGATATGCCCTGCTTTGAGAATATAGAGTCTACGCCTGAATCGATGGCTGTGCAGCAGAGCCGGCAGCTGGAGCTGACGCAGCTCTTTAATGACCTGCAgccagcacaacaacaacaacaacaacagcagcagcagcagcagcaggaaactGTCAGCTATGAGACACTATATCAAACAACATCAATTCCTatcgccaacagcaacaacaacaaattgcaagtcATACAAATGACGCCACAGGAGACGCTGTGGCAGGCACCcccagtgcagcagcaacaacagcaattacagcaacagtcgcaggcgacaacagcaacacaattGCAATGGTCCACTGTGGGCGGCTTGGAGGCGATCAAGACGACGCCCAGTCTGGATAATCtggacagcaacaacagcaacatcaacaacaacaacaacactacgacaacaaccacataCTACATTAGTGCCAGTGATCTCTatcaaacacaacaacaacatcagcagcaacagcctgGCGAGACTTATGCTCTGCTCGACAGCAATGATAACTTTGTGctggaacagcagcaacagcagcagcaacaaccacatcagcaacagcagcagcagcaaccaattATGATACTCATACAGCAACcggagctgcagcagccagtGGCTTCGGCCAGCAATCCGCAGCAGGCGCCGCTTCATATTAACTACAGCAGTGAGCTGCAAActtatcaacagcagcagcagcagcagcagcagcaacatcaacatcaaaaaccatatccacatccacaacaacaacaagtacaaaaTACAGTATTAGGCTTACCAGGAGCAGCGGTGTCGCTGCCAACACGCGGTCGCCCGCCAATATTGAAGTGCCGCTTCTGCCAGAATGGACCGCGCTTCTCGAGCAGTCTGGAGTACAGTCGCCATATCATTGAGCTGCATCCCGCCGTGGCGCCATTCAATTGCCCGCACTGTCCGCTCGCCTTTGCCGGTCGCAGCAAACGCAATCAGCACATCCTCAGCAGCCACATGGTGCAGCAGTTCCACTGTGGCCAGTGCTCCCAAATGTTGCCCTCGCAGCGTGCGctcgatttgcatttgcagcgaTTTCACATGCCACTCGCCACGGAGCCAGCATCGCCGTCCGGcgtcacagcagcagcagcagcagcagctggtgtGCGTCTAGAGGAGGTTCAATTGCGCATTGCCACCACCAATgatctgcagcagcaacagcagcagcaacaacagcagcaacaacagcagcaacagcagcggcaaccaCTTCAGCAGCAATCAGTTGCACAAATGCGAACCTTGGAATTGCAGGCAAACTCAACCCGACCACGTAGGACGCGCATACTGTGCTGCCCGGACTGCGAGGACTGCACTTCGGTCAGTGGACACAATCAATGCGGCGGGCAGCCGTACGAGGAGCTGAACACGTTGCAACCACCGCCCACGGTGCTGACACCGCCGTCGACAATTGCATCGCTGCCATCACCGCAGCCGGCGGCGCATATAACGTTGCCGTCACCGGAGCAATCCGAGCCAGACTCGACGACGGCCACGTTGCGGCAATTTCGCAAACGTTGCACGACAACATTAGCAGccgcagtagcaacaacaacatcaacaaccacaaccacaacaatgcTAACAGCGGCTGCCTCACCATCGCCGTCATCATCGCCATCATCGTCAACGATGGAGTCAGCAAGCGCCACGCTGCAACTGGGCAAGCTGCGTGGCAGTCATCAGTGCGTCATCTGCGAGAAGCGTTTCACCAACATTATTGCGCTGCGCAAGCATCAGCAACTGGCCCACGATTCACAGACGACGATGCCGTGGGTCTGTTCGATCTGCAAGCGAGGATATCGGAAACGCACCGACATGGATAACCATATGAAATCGCACGAGCCAAAGGGACGACCCTATGAGTGCAACGAGTGCTGGGTGCGCTTTCCAGAGTTCAAGCAGCTGGCGATGCACAAGTTCACCGTGCACGAACTGATCAAGCCGCACACCTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAGTTTCACGGTGTGCGAGGCTTCGAGTGCGATGAATGCGATGAGGCATTCGCCTACATCAAAGATTTGCGGAAACACCGCCGAACCCACAACAGCGAACTATTTTACAAATGCGATTATTGTCCGCGCACGTTTCTGCATTTTACGAGCTATCGTGCACATATGAATACCCACCTGCCGCTGGGTGTATTCCTTAACGACCAGATGCCCAGCAGCGTCTGCAGCAAATCGGAGAATCCATCAAACGCTGAAGAATCGCTGCTGCCATTGACGCCACTGAGCAACTGCAATGgaaacagtggcaacaacagtggATTAGAGGACTGTCCCGGCTCTGTGGAGATGGTGGTGGAGAGCAGCATGGTGGCGCCATCGCTGGACATGATTGTGGATACGCCATAA
Protein Sequence: MSANKRRRCNSNNSSTADQIDKQVQSKECKEMPTIDVQRLCRCCGKGDIELLKLFEESATTANQKTQTQIAIAQVRQRQTTTAGETEGTAQQEQEQQQEQKQQQQRKSDNPVEYALSGAHSSMDIVLEEMNIWTLNISRDDGLPQEICRQCKAQFIMVAKFRRRCIRVQQRLQDYNQDMTKSSSQKKKEQRTQQSQTKPQANEASAADYMHLPQSVKERKRRLVPNTETSALPKYAKTDDTQLLMTPKQRRIQLGVCTTRCNSLPACKFETETETKVGAGPEAGAGARATETTGDYRLSETKPRTPQRSPYRARLIHVPWRTKAARKQITEMRSTDSEQESAKAMATTTLMIKTADASANSSEDLSDLSVSACQGFDNGCSSSNSSPKSTTNSKLRFPPKRCSPIKARVLRRLERCNYAPFKRTRRVFKKATARSEAPKQELSCVEMPSTEATKETQTIDQITNNSANEETTSSRSSSSSSSLETPEMIDEEAQNGMPEMESNVQQQEISIVDEKAQNGMPEIESSAQQEDAHIENTKEELQPDEAIKSAPETQHIKLMAQMESISEEVIKTDGAVNGTVEATLMSPVQLEELSSSSTGHMEGERRQSATPELPAAEYEVEVSLTNEEQTSDQMSEQLSEQLSDQMSEQMSEQTSEQMSDQMSNQMSNQLSNQLSEQTSNQTSDQMSEQTLELIVNIPLDALGQKLQRKLCNESETSTNDELEQPAGVERKEPAESDDVNNNEKSEHFYQSAIADSFNAAVALATKQIEAEPGGDDDVDVDVDDDDDDMESLEKLPNLQHEQQQQQQQQQPRTSASSMDFLAEFEKHCEKSIKLQAAGQELAEAKQQLAVEMNYVANTLHGILNEMQDEHLYTPVCTPIDEFLTPADYAPPTPASPNLYEQPVEAQQQQQQQQQQQQQQQQQHQKEGNLFDSSTFSNEMIGFQNDMPCFENIESTPESMAVQQSRQLELTQLFNDLQPAQQQQQQQQQQQQQETVSYETLYQTTSIPIANSNNNKLQVIQMTPQETLWQAPPVQQQQQQLQQQSQATTATQLQWSTVGGLEAIKTTPSLDNLDSNNSNINNNNNTTTTTTYYISASDLYQTQQQHQQQQPGETYALLDSNDNFVLEQQQQQQQQPHQQQQQQQPIMILIQQPELQQPVASASNPQQAPLHINYSSELQTYQQQQQQQQQQHQHQKPYPHPQQQQVQNTVLGLPGAAVSLPTRGRPPILKCRFCQNGPRFSSSLEYSRHIIELHPAVAPFNCPHCPLAFAGRSKRNQHILSSHMVQQFHCGQCSQMLPSQRALDLHLQRFHMPLATEPASPSGVTAAAAAAAGVRLEEVQLRIATTNDLQQQQQQQQQQQQQQQQQRQPLQQQSVAQMRTLELQANSTRPRRTRILCCPDCEDCTSVSGHNQCGGQPYEELNTLQPPPTVLTPPSTIASLPSPQPAAHITLPSPEQSEPDSTTATLRQFRKRCTTTLAAAVATTTSTTTTTTMLTAAASPSPSSSPSSSTMESASATLQLGKLRGSHQCVICEKRFTNIIALRKHQQLAHDSQTTMPWVCSICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGVRGFECDECDEAFAYIKDLRKHRRTHNSELFYKCDYCPRTFLHFTSYRAHMNTHLPLGVFLNDQMPSSVCSKSENPSNAEESLLPLTPLSNCNGNSGNNSGLEDCPGSVEMVVESSMVAPSLDMIVDTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00499169; iTF_00500610; iTF_00552581; iTF_00535609; iTF_00511582;
90% Identity: iTF_00511582;
80% Identity: -