Basic Information

Insect: Drosophila melanosoma
Gene Symbol: -
Assembly: GCA_035042045.1
Location: JAWNLY010000178.1:7161301-7163793[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 4.8 3.3e+02 2.0 0.7 3 23 36 58 34 58 0.88

2 8 0.044 3 8.4 0.2 2 23 125 147 125 147 0.90

3 8 4.1e-06 0.00028 21.1 3.0 1 23 165 188 165 188 0.98

4 8 8.3e-05 0.0057 17.0 2.1 2 23 300 321 299 321 0.96

5 8 0.0038 0.26 11.7 5.8 1 23 327 349 327 349 0.98

6 8 5.5e-06 0.00038 20.7 2.4 1 23 355 377 355 377 0.96

7 8 1.7e-06 0.00011 22.3 3.0 1 23 383 405 383 405 0.99

8 8 0.00014 0.0093 16.3 3.7 1 20 411 430 411 432 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	4.8	3.3e+02	2.0	0.7	3	23	36	58	34	58	0.88
2	8	0.044	3	8.4	0.2	2	23	125	147	125	147	0.90
3	8	4.1e-06	0.00028	21.1	3.0	1	23	165	188	165	188	0.98
4	8	8.3e-05	0.0057	17.0	2.1	2	23	300	321	299	321	0.96
5	8	0.0038	0.26	11.7	5.8	1	23	327	349	327	349	0.98
6	8	5.5e-06	0.00038	20.7	2.4	1	23	355	377	355	377	0.96
7	8	1.7e-06	0.00011	22.3	3.0	1	23	383	405	383	405	0.99
8	8	0.00014	0.0093	16.3	3.7	1	20	411	430	411	432	0.95

Sequence Information

Coding Sequence: ATGTGCTCCACATCGGTGCTGTGTCCACTGTGCGCTGTGCCCAGTTTTAATAGCATCGATGCACTGCAGCAGCGTCTGATTAAGGCAGCCAATGGACCCTTGGCCTGCTCATTTCCACACTGCAAAGAGCAGTTCCTGGGCCTGGATAAGTTAACCATACATCTGTTTAGTCACACGAGTCTGATGAACAGAGTGGTTGAAGTTCCAGTAGTTACAAAAGTTCCAGAAGCTGCAGTCAGTTTGCCAGCGCCGCCTGTTGCAGCGCCTACTACTCCGCCCACCGCGGCAGCGCCGAAGCGGCGTGGCAAAAAGTCGCGAGCGAAGAATGTGGAACCACCGCCACAACCGCCGCTGCCTACTACACCGCCGGCTCGCTGTGACATCTGTGAGTTTAGTTTCCGCAACGACGAGTTGCGCGACATTCACATCCGGCTGGTCCACGAGAATGGAGTGGAGAGTACGGCAACGCaaccgctgcagcagcaggagccgTACAAATGCCATCTGTGCTCCAAGACGTTTCGCATGAAGGGTTCACTGCGTGTCCATCTCAAAGTGCTGCACACAGTTGGCAGcagctccaacaacaacaacagcaacaacaattcgagcagcagcaatggcaaccaGATGCTAAATCCCACGCCAAAGATAAGCATTTGCGATCGCATTCGACGCAAGGAGGCAACGGCTTTGGCTAATGGCAACACCATCACttcaggcaacaacaacaacaacaacaatacaaacaactccaacagcagcagcagcaacaacaacaacaacaacacccaaCCATATGCACTAAGTGGTGCCATTTGCATGCTGAAGCAGGACACCACAGGTGCAACAGAGTCAGCGAACAGCTCGGAGTACGGAAGCACGCCGAAGAACTGGGAGTGTGATGTGTGCACCAAGCTCTTTACCACCAAGTACTTCCTGAAGAAGCACAAGCGACTCCACACCGGCGAGATGCCATACACGTGCCAATACTGCGCTCGCACCTTCACCTTCCAGCAGTCCTACCACAAGCATTTACTCTACCACAGCGAGGTGAAGCCGCACGCCTGCAACATCTGTGGACGCGCCTTCAAGGAGCTATCGACGCTACACAATCATCAGCGCATCCACAGCGGCGAGAAGCCCTTCAAGTGCGAGGTGTGCGGTAAATGTTTTCGGCAACGGGTCTCCTTTCTGGTGCACACCCGCATCCACACTGGGGTTATGCCCTACAAGTGTGAGCAGTGCCAGAAGACTTTTCGGTACAAGGTCTCGCTGCGCACACATAAATGCGCTGCTGGCACTGAGGAGGCGCAGACACCAGAGCAGCTGATCAAGGCACTGCTGGAGTCGAATGCGGTCGGCGTGGTGGGCCATGTGCAGACAGAGCATTCGGCAGCGGGAAGTGGGACAAGTGCTGGGGATCAGGAGGCGTTGCTCTCGCAGACGATCGATGACATTGTCGTCGAGAGCTGCCAGAAGCTGGGCATTTGTGGTGTGGAGCCACCACAGCAGGTAATCCTGGACAATGGCAATGTGCACTTCGATGGCAGCAATTCaccgctgcagcagctgcagaatTTGCGCCTCTACTCGCCACCACAGCAGCCGGAGCAGCCCAGCTCCGATGGGGAGCTCTTTCGCCACTTCCTCATGGACGCCACGTAG
Protein Sequence: MCSTSVLCPLCAVPSFNSIDALQQRLIKAANGPLACSFPHCKEQFLGLDKLTIHLFSHTSLMNRVVEVPVVTKVPEAAVSLPAPPVAAPTTPPTAAAPKRRGKKSRAKNVEPPPQPPLPTTPPARCDICEFSFRNDELRDIHIRLVHENGVESTATQPLQQQEPYKCHLCSKTFRMKGSLRVHLKVLHTVGSSSNNNNSNNNSSSSNGNQMLNPTPKISICDRIRRKEATALANGNTITSGNNNNNNNTNNSNSSSSNNNNNNTQPYALSGAICMLKQDTTGATESANSSEYGSTPKNWECDVCTKLFTTKYFLKKHKRLHTGEMPYTCQYCARTFTFQQSYHKHLLYHSEVKPHACNICGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTGVMPYKCEQCQKTFRYKVSLRTHKCAAGTEEAQTPEQLIKALLESNAVGVVGHVQTEHSAAGSGTSAGDQEALLSQTIDDIVVESCQKLGICGVEPPQQVILDNGNVHFDGSNSPLQQLQNLRLYSPPQQPEQPSSDGELFRHFLMDAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01324381;
90% Identity: iTF_00518645;
80% Identity: -