Basic Information

Insect: Drosophila melanosoma
Gene Symbol: SCRT1
Assembly: GCA_035042045.1
Location: JAWNLY010000145.1:4652514-4656133[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1.6e-07 1.1e-05 25.5 1.8 1 23 498 520 498 520 0.99

2 5 0.1 7 7.2 0.0 5 23 533 551 530 551 0.92

3 5 4.3e-06 0.0003 21.0 0.5 1 23 555 577 555 577 0.97

4 5 1.1e-08 7.3e-07 29.2 0.5 1 23 583 605 583 605 0.98

5 5 8.8e-05 0.006 16.9 2.7 1 21 611 631 611 632 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1.6e-07	1.1e-05	25.5	1.8	1	23	498	520	498	520	0.99
2	5	0.1	7	7.2	0.0	5	23	533	551	530	551	0.92
3	5	4.3e-06	0.0003	21.0	0.5	1	23	555	577	555	577	0.97
4	5	1.1e-08	7.3e-07	29.2	0.5	1	23	583	605	583	605	0.98
5	5	8.8e-05	0.006	16.9	2.7	1	21	611	631	611	632	0.95

Sequence Information

Coding Sequence: ATGTCCGTGGATTTCATGCTGCCCAATCGCAATAAGATACAAACGATTGCGTATGCGAGCAAGAAATATGCCAGTGTTGCCGCCGAAATACAAAGCTGGCGACGTCCCAAGCCGAAACCAAAGCCGAGAGCCAAGTCGAAGACAGgcggacagcagcagcaacagctacgcAAACTGAGGCTATCTGAGAAGCTGCCAGTGTTGCGTAatgccaataacaataataacaatagcaacgcTAAACTGAGCTTCAGGTCTAACGGCAAACGGGGCACCAGAGTTACCCTAAAGCGGGAAATAATCGAGCTGGGAAAAGAGGTTAAGGCGGAGTCGGAAGCGGAGGcggatgatgataataatccGCCGGATGAGCATTTGGAATGGTCGGCGGCACAGTCGCTGGTGCAAATGAACTCCAAGCAGGAGAAACAAAGACGACTGGGTGTAACGGGAACGGGAGCAGGAGCATCAGAAGCTATTACAGTAACAGGAggtggagttggagttggagcaacaacaggaacaggagcaggagtaggagGAGCAACAAGCAAACTTGTATCAACAGCCGCAGTATCGATGCGCCGTCCAGTGGCCTTTGGTCGCGCCCCCGCCGAGGATGGCAAAGTGATTTTCTATGCGCCGCccgcaaatgcaaatggcgcCCAGCGCCAGCCCCAGCCCGTGGCCATAAAACGTGAGCGCGAAAGGGAAAGAGAACGCGAAAGGGAACGGGAGCGGGAAAGGGAATGCGAAAGAGAACTGGATGTGGAACGTGAGAGGGCAAGGGAACTGCAAGTGGAACGTGAGCAGCAACAGGTTGCCATTTATCGCGGACGCAGTGTTGAGGAAACGGAAGCAGCGCACGATCTGCTCTCTCTGTCGCAGAGCTTGCCACCGTTGATACCACCCTGTGTGGTGACAATAATGAGGCAAGAGTTGAGCTCGaaacagttgcaactgcaacatcagcaacaattgtTAAACGGCAGCAGCATGCAGGAAATATGCAACAGCAGTCAAGCAAAATCCACAGGCAGTGGTGGCAATATCAGATTTATTGGCAGCACCTCTTACGATttgttgccacatgccacacaggAGCATagcaataatagcaataatcataataataataacacaaattGTTCGCCGTTGACGCCGCCCAATTCCGATCACAGTTCCGATGTGGACATCGATATATCATCCTCCTCCGAGTCGGGGCAGTTGCACTGGCACAAGCAGTCGCCGCAgtttcaacagcagcaacagcagcaacgtgCCTCCAGCTTAAAGCTGTGCCTCAACATGCTCGATGGTCGCACCAAGGCCAGCAAAGCGGCAGCCGGTAAGGATAAcaacaaggagcagcagcagcatcagacGAAaggcaagtgcaacagcagcagcagtagtagcgAGGCGGTTGCAAGTGgcgcaacagttgctgctgctctagGCGAGAATTACGCAAAGCGCAAGCGGGGCTGCTACAAGTGCTCCGAGTGTGGCAAGCAATATGCGACCTCCAGCAATTTGTCGCGCCACAAACAGACGCATCGCTCGCTGGACTCCCAATCGGCCAAGAAGTGCATCAGTTGTGGCAAGGCCTATGTCTCCATGCCCGCTCTGGCCATGCATCTGTTGACGCACAAACTTTCGCACAGTTGCGAAATATGTGGTAAGCTATTTTCCCGCCCCTGGCTGTTGCAGGGGCATCTGCGCTCGCACACGGGCGAGAAGCCCTACGCTTGCGTCCATTGTGGCAAGGCCTTTGCCGACCGCTCGAATCTCCGTGCCCACATGCAAACCCATTCGGGGGATAAGAATTTCAAGTGTCATCGTTGCACCAAAACTTTTGCCCTCAAATCTTATCTGAATAAGCATTTGGAATCTGCTTGCCTGAGGGATGTAGGCGCCATACCCAGCAGCAAGGATGACCAcaacgaggaggaggatgacgaGGACgaagaggagcaggaggaggagcaggatcaagatcagctgctgctggacgATGAGCTGGACAGCGATGAGAATAGTCAGGATATTGTcgttgcttaa
Protein Sequence: MSVDFMLPNRNKIQTIAYASKKYASVAAEIQSWRRPKPKPKPRAKSKTGGQQQQQLRKLRLSEKLPVLRNANNNNNNSNAKLSFRSNGKRGTRVTLKREIIELGKEVKAESEAEADDDNNPPDEHLEWSAAQSLVQMNSKQEKQRRLGVTGTGAGASEAITVTGGGVGVGATTGTGAGVGGATSKLVSTAAVSMRRPVAFGRAPAEDGKVIFYAPPANANGAQRQPQPVAIKRERERERERERERERERECERELDVERERARELQVEREQQQVAIYRGRSVEETEAAHDLLSLSQSLPPLIPPCVVTIMRQELSSKQLQLQHQQQLLNGSSMQEICNSSQAKSTGSGGNIRFIGSTSYDLLPHATQEHSNNSNNHNNNNTNCSPLTPPNSDHSSDVDIDISSSSESGQLHWHKQSPQFQQQQQQQRASSLKLCLNMLDGRTKASKAAAGKDNNKEQQQHQTKGKCNSSSSSSEAVASGATVAAALGENYAKRKRGCYKCSECGKQYATSSNLSRHKQTHRSLDSQSAKKCISCGKAYVSMPALAMHLLTHKLSHSCEICGKLFSRPWLLQGHLRSHTGEKPYACVHCGKAFADRSNLRAHMQTHSGDKNFKCHRCTKTFALKSYLNKHLESACLRDVGAIPSSKDDHNEEEDDEDEEEQEEEQDQDQLLLDDELDSDENSQDIVVA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00564858;
90% Identity: iTF_00535539;
80% Identity: -