Basic Information

Insect: Drosophila melanosoma
Gene Symbol: -
Assembly: GCA_035042045.1
Location: JAWNLY010000177.1:3330713-3334045[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0025 0.17 12.3 0.1 1 23 224 246 224 246 0.98

2 7 0.049 3.3 8.3 5.7 1 23 595 617 595 617 0.98

3 7 4.9e-06 0.00034 20.8 0.9 1 23 623 645 623 645 0.99

4 7 6e-06 0.00041 20.6 0.8 1 23 651 674 651 674 0.97

5 7 1.4e-07 9.8e-06 25.7 2.5 1 23 680 702 680 702 0.97

6 7 6.5e-06 0.00044 20.5 0.7 1 23 708 730 708 730 0.98

7 7 1.7e-06 0.00011 22.3 1.0 1 23 736 758 736 758 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0025	0.17	12.3	0.1	1	23	224	246	224	246	0.98
2	7	0.049	3.3	8.3	5.7	1	23	595	617	595	617	0.98
3	7	4.9e-06	0.00034	20.8	0.9	1	23	623	645	623	645	0.99
4	7	6e-06	0.00041	20.6	0.8	1	23	651	674	651	674	0.97
5	7	1.4e-07	9.8e-06	25.7	2.5	1	23	680	702	680	702	0.97
6	7	6.5e-06	0.00044	20.5	0.7	1	23	708	730	708	730	0.98
7	7	1.7e-06	0.00011	22.3	1.0	1	23	736	758	736	758	0.98

Sequence Information

Coding Sequence: ATGGAGCGCAAAGAAGTGGACGCCGAACAGTTCATCGACCACACGCTGCTGGCGACGGAGCTGATGATGGATCTAATGGATCACACTGGCGTATTTCCCAAGGCAGAAGGACCCACCAATCTCAGCACAAGCGGACATGTCGCCACAGCTGGCTCTCCGCAGGAGCTCAATTTCCACAATACGATTTTTCAGTTTGTCAACAAACATGTTGTCGGTGACGGCGTGGACGACGAGGAGGTGGTGGGTGGCGGATCAAAGGTGTCTGGCAAGGAAACAGATGTAGAATTCCTcaccatcaacagcagctTCCTCGATCGCAGAACAGAAAGAACACCGGGCGCAACGGGCAGCGCCGACAATGTAGTGACAcagcaagaacagcagcaggtgcCACAGCCAGCATTTCCGGCACTGGCCATTGAGCCAACGGTGCCGATCGATGTGTCAAATGCGTTGGAAGATGAGGATTTCCTCTATGCGCACAATGCGTGCACAATCAATGCCCGCAAAGTGTTGCCGCACAAGAAGCGAATCTCGCGTAAACTAAAAGGATCGATGTGCAGCATGGATACAGCGGATTTggagcaacatcagcagcacaaGCATCATGTGCATCAGGTGCAGGTGCAACAACAGGTGGTGCAGCCAACGGTGCAGCAGGTTGCCAACTATAGCTGCGAAATCTGCGGCTACGCGGTTCAAACACAAATCGAATTTTATGCACATCTCAAACAGCACTATGATCCCGTGCATGATCTTGAGCAGCGTCTCGATGTgcctcaacagcaacagcagcaacaacagcagcagcagcttcaaaAAGAGCCGTTGGATATGTGCGGCCTATCAACACAGGATAAGGAACAGGCCAAATTAGATCAAGTCTTTCACGATGTGCAACTGAACTTTGAGAACTTCCACAACATCAGCCACCATCATGTGCATGATGATGTAAGCGTCAATATGGTCATCCATTCAGATGCAATGTCAATGCACAACAAAACTAGCGATGGTAAACTGACgccagttgttgccacaaatgcaGCAACTGTCTCGCATGATGTGGCCGTTGCTGTGGACGATGTGGAGTTTAGTGACTCCGAGGACATGCTCGGTGGTATGCGCGATGTGGTCGATAAGGTCTCAATAGAGGATACCTGCGATGAGCTCGTCGACTTGGAGCTGACCGCCAGTGGCATGCGTGCACCTtggtttaataataattttagtgATATTGGATTTTCGGGTCTGTTGCTGCCAGGTgaaccaccaacaccaacacaaccACCTCAATCAGCGACAACAAGATCAGCAACAAGCACTGAAGAGGATCCGCTGCTCAAAACGCAGCCGGAGCAACAAATGACACTGAGTTTTCTCAACAAGCcggatgagcagcagcagcagcaatctgTGGTGCATCACAAACTGGAAATGGGACACAAGAAGAACTATATTGCAGCCGCTGCATTCAATGCCATCCAATCCAATGGCCATGGCAACGAGCAGACGCTATTGATTACCTCGCCGGAGCACACATCATCTTTATCGCCAAACTCGGGCTCGGCCAttgagcaactgcagcgcTCGCCGCTAATCATTAGTGATTCGTTCAAGCTGGAGGATGTGGAGAGCAGTGTGCCAGCGGGCAGCATTGCATCCTCCTCGCCAGCAGCCACAGTCATTGAAGACGACGGCAATGCCGATAGATATCTGTTGGAGCTGGACAACAAGTCCGCCAGCGATGatcccagcaacaacaacgaggtGACAAAGCGCAAATTCCATTGCGATAAGTGCGCCAGGGACTTCAATTCATACAATGCCCTTAAATATcatcagcacacacacagcaaggAGCGTGCATATCAATGTGCCACCTGCCAGGCTTCCTTCTACACGCCCAGTTCCCTAAAGCAACACGAACGCACACACTCTGGCATCAAGCCGTTTAAGTGCGAACAGTGCGATTTCAAGTTTCGACAATGGGGCGATCTTAAGTTGCACATCATCTCGCGGCACAGCGAGATAAAGGCGCACATGTGCGAATACTGTGGCAAGAGCTTCTCCCGGAAATACTCGCTTGTTGTGCATCGTCGAATACACACGAGCGAAAAGAACTACGCGTGCCAGTATTGTGAGAAGACATTTCGGGCCAGCTCCTATCTACTCACCCACATCAAGGTGCACACGGGTGAGAAGCCCTACTCGTGCTCCGTTTGCGACAAGAAATTTCGGGTGAATGGTGATCTGAAGCGACACTCGCGTATCCACGATCCGTCGAGACTAACGCAGCGCAGCAAACGCTGGAAGCAAATCGAAGATGAGGtggacgaggaggaggaggaggcgatGAATAAGTCTGATGCCGTTTGTGGCGAAAGTGAACAGGAAATTTTGGGCTGTTAG
Protein Sequence: MERKEVDAEQFIDHTLLATELMMDLMDHTGVFPKAEGPTNLSTSGHVATAGSPQELNFHNTIFQFVNKHVVGDGVDDEEVVGGGSKVSGKETDVEFLTINSSFLDRRTERTPGATGSADNVVTQQEQQQVPQPAFPALAIEPTVPIDVSNALEDEDFLYAHNACTINARKVLPHKKRISRKLKGSMCSMDTADLEQHQQHKHHVHQVQVQQQVVQPTVQQVANYSCEICGYAVQTQIEFYAHLKQHYDPVHDLEQRLDVPQQQQQQQQQQQLQKEPLDMCGLSTQDKEQAKLDQVFHDVQLNFENFHNISHHHVHDDVSVNMVIHSDAMSMHNKTSDGKLTPVVATNAATVSHDVAVAVDDVEFSDSEDMLGGMRDVVDKVSIEDTCDELVDLELTASGMRAPWFNNNFSDIGFSGLLLPGEPPTPTQPPQSATTRSATSTEEDPLLKTQPEQQMTLSFLNKPDEQQQQQSVVHHKLEMGHKKNYIAAAAFNAIQSNGHGNEQTLLITSPEHTSSLSPNSGSAIEQLQRSPLIISDSFKLEDVESSVPAGSIASSSPAATVIEDDGNADRYLLELDNKSASDDPSNNNEVTKRKFHCDKCARDFNSYNALKYHQHTHSKERAYQCATCQASFYTPSSLKQHERTHSGIKPFKCEQCDFKFRQWGDLKLHIISRHSEIKAHMCEYCGKSFSRKYSLVVHRRIHTSEKNYACQYCEKTFRASSYLLTHIKVHTGEKPYSCSVCDKKFRVNGDLKRHSRIHDPSRLTQRSKRWKQIEDEVDEEEEEAMNKSDAVCGESEQEILGC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00583127;
90% Identity: iTF_00511462;
80% Identity: -