Basic Information

Insect: Drosophila melanosoma
Gene Symbol: -
Assembly: GCA_035042045.1
Location: JAWNLY010000086.1:513696-518237[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.00048 0.033 14.6 0.9 1 23 213 235 213 235 0.97

2 26 0.00035 0.024 15.0 4.1 1 23 241 263 241 263 0.98

3 26 0.021 1.5 9.4 0.4 2 23 296 317 295 317 0.96

4 26 0.014 0.97 9.9 4.2 1 23 393 416 393 416 0.94

5 26 0.11 7.6 7.1 0.6 2 22 426 446 426 446 0.96

6 26 3.8 2.6e+02 2.3 0.5 1 19 455 473 455 475 0.92

7 26 4.7 3.2e+02 2.0 0.3 2 23 502 523 501 523 0.93

8 26 0.0042 0.29 11.6 0.5 1 23 597 620 597 620 0.96

9 26 0.03 2.1 8.9 0.1 1 22 629 650 629 650 0.95

10 26 0.0062 0.42 11.1 3.5 1 23 659 682 659 682 0.96

11 26 0.00017 0.012 16.0 0.4 2 23 696 717 695 717 0.97

12 26 1.3e-05 0.00091 19.5 5.2 1 23 723 745 723 745 0.98

13 26 0.013 0.88 10.1 1.2 1 23 884 907 884 907 0.95

14 26 0.0045 0.31 11.5 2.2 1 22 914 935 914 935 0.96

15 26 0.37 26 5.5 0.4 1 20 944 963 944 967 0.86

16 26 5.4e-05 0.0037 17.5 1.6 1 23 991 1013 991 1013 0.97

17 26 0.00041 0.028 14.8 0.7 1 23 1020 1042 1020 1042 0.98

18 26 0.037 2.6 8.6 0.0 2 21 1069 1088 1068 1089 0.94

19 26 0.036 2.5 8.7 4.0 1 23 1134 1157 1134 1157 0.96

20 26 0.0073 0.5 10.9 1.0 1 23 1194 1217 1194 1217 0.96

21 26 0.013 0.9 10.1 3.1 1 23 1244 1267 1244 1267 0.97

22 26 1.2e-05 0.00085 19.6 0.1 2 23 1288 1309 1287 1309 0.95

23 26 4.2e-05 0.0029 17.9 2.9 1 23 1315 1337 1315 1337 0.99

24 26 3.9e-06 0.00026 21.2 2.3 1 23 1343 1365 1343 1365 0.97

25 26 2.6e-07 1.8e-05 24.8 2.6 1 23 1371 1393 1371 1393 0.99

26 26 0.00077 0.053 13.9 0.6 1 21 1399 1419 1399 1423 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.00048	0.033	14.6	0.9	1	23	213	235	213	235	0.97
2	26	0.00035	0.024	15.0	4.1	1	23	241	263	241	263	0.98
3	26	0.021	1.5	9.4	0.4	2	23	296	317	295	317	0.96
4	26	0.014	0.97	9.9	4.2	1	23	393	416	393	416	0.94
5	26	0.11	7.6	7.1	0.6	2	22	426	446	426	446	0.96
6	26	3.8	2.6e+02	2.3	0.5	1	19	455	473	455	475	0.92
7	26	4.7	3.2e+02	2.0	0.3	2	23	502	523	501	523	0.93
8	26	0.0042	0.29	11.6	0.5	1	23	597	620	597	620	0.96
9	26	0.03	2.1	8.9	0.1	1	22	629	650	629	650	0.95
10	26	0.0062	0.42	11.1	3.5	1	23	659	682	659	682	0.96
11	26	0.00017	0.012	16.0	0.4	2	23	696	717	695	717	0.97
12	26	1.3e-05	0.00091	19.5	5.2	1	23	723	745	723	745	0.98
13	26	0.013	0.88	10.1	1.2	1	23	884	907	884	907	0.95
14	26	0.0045	0.31	11.5	2.2	1	22	914	935	914	935	0.96
15	26	0.37	26	5.5	0.4	1	20	944	963	944	967	0.86
16	26	5.4e-05	0.0037	17.5	1.6	1	23	991	1013	991	1013	0.97
17	26	0.00041	0.028	14.8	0.7	1	23	1020	1042	1020	1042	0.98
18	26	0.037	2.6	8.6	0.0	2	21	1069	1088	1068	1089	0.94
19	26	0.036	2.5	8.7	4.0	1	23	1134	1157	1134	1157	0.96
20	26	0.0073	0.5	10.9	1.0	1	23	1194	1217	1194	1217	0.96
21	26	0.013	0.9	10.1	3.1	1	23	1244	1267	1244	1267	0.97
22	26	1.2e-05	0.00085	19.6	0.1	2	23	1288	1309	1287	1309	0.95
23	26	4.2e-05	0.0029	17.9	2.9	1	23	1315	1337	1315	1337	0.99
24	26	3.9e-06	0.00026	21.2	2.3	1	23	1343	1365	1343	1365	0.97
25	26	2.6e-07	1.8e-05	24.8	2.6	1	23	1371	1393	1371	1393	0.99
26	26	0.00077	0.053	13.9	0.6	1	21	1399	1419	1399	1423	0.91

Sequence Information

Coding Sequence: ATGTTGCCGGCGAATGTTTGTCGCACGTGTGCGTTGCAAGATGACAATTTGTTGGCGCTGACAACGCGGAGTGAGAAATACACAAAGAAAAGTATTTGCGACATGCTGCACGAATTAACACAAAATGATCCGCTGCTTGAGCATACAGATGATAAGCTGCCGCAGCATTTATGCGGCCAATGCTTGAGCCAGTTGGAAGCTGCCTATACGTTTGTGCTACAGGCCCGCGAGGCGCAGGAGCAACTATTGCTGCAGCTACGCAAAGGATTGCAGACACAGTGTCTGGACGAAACTCCCATCGATATAAGCATTGAACACATAAAAATGGAAGCAGACATGGACCTATATGCGGATACGGCCGACACAGTCGATACTAAGTTGGAAGAGAAGCAGGGGAAGCAGGTTGCATTGAAATGCCAGGTGGAAACTGATAGCGATAGCAGTCAGGAAAATGTGAAGGACTTTGACTTTGAGGTCAATACACCGCAGCTGCGGCGCAGTGCTCGGCGACCCAAGTTGAGCACAGAAAGCGATGAGTCAACCTCTGAGAAGGTGAAACCGGCGCCTGTTAAGCGTGGACGCGGGCGTCCCGCACGTCTGGCCAAGAGGAAGACGACCACCAACGAGGATGGTCGGCATGTGTGCGAGGTGTGCGGCAAGACATTCTCCTGGTATCGCGACATGCAGCGCCATGCGCGCATCCACTTTGAGCAGGCGGGTTTTGTGTGCGAGCACTGCGGCAAAAAGTTTCTGCGCAAGGACAAGTACATGACCCATCTGCGATCGCACAAAAAGCAGATGGTCACAGACAGACTGGTACTGCCACGGAGCATCGAATGGCGCTACGCGGAGCGTCTATACAGCTCCGGCAGATTAATGCGTGTCGAGTGCAAGCTGTGCGGGTTGAGCTGCCAGCGCATTCAGGAGTTGCGCGAACACTTGGCGATTCACGTTCGCATTGAAACATTGTCGAACCTCAGCCTAGACAACGATGTCATACAGGAGCAGTTTTCCGACCAATTAGATTTGCAGCAAATCAAGGAACAGGTGTGCACAGAAATTGCCAAAGGTCGCGAACAATTAGAGAATTACGGCACCGTGGTGAATTTTTACGGCTATGAGCTGTACCTTAGCGACTCagatgatgaggaggaggatgaaGAGCTGCCTGCCAAATATCAATGTCGGCGCTGTGATGTCAACTTTGCACGCAAGCATCAATTCATGCATCACACGATCGAGGAGCATACCGACAGAAGTGAGCCTCCTTTGGAACGCTGTAATATTTGTCAAATTGGCTTTGTATGCCCCAAGCTGCTTGAACAGCATCAGCGCACGCAGTGCCTCAATCCTCTGAAGCGCTATAGCTGTGAGAATTGTCCTGGCAAGTTTATTTGGCTACAAAATCTAAAGCAGCATGCATGCTGCGCACTGAAACAGGATCTGCAACAGGAACTACAGCATCGGcatcaggagcagcaacaggcacCTCATCGCCAGATCCAATGTTGCCTGTGCAATGAGCAACCCAGTAGCATGGCTGCACTACGCTCTCATTTACTTATTCATTGCGATGGACACACGGACGTAGATCCAGACAAGCAGTCTGCCTTCTTTCGCACCTATTACCAAGATGACGGCGCCAGTAGCCTGTCGGATATCAGAACACGAATCGCTAGCGACTTTGACGCGCAGCtttatggaaaatatttcaatgcgTGCACGGATAGCGGACAGGAACTGGACTTCAACGACTCCGATAAGGAGTGGAGCGATGCCCCAGCACTGCACAGCTGTGCCGTGTGTGGCGAGAGTAGAATCCGCCTTGATCAGCTgcttcagcatcagcagagCCAACACTTTGAGTTGGCGGGAAGACTGCCTCATGTCTGCTTAGATTGTGGATTGGGCTATGTGGCCGAGTcactgctgcagcagcatcgtCGTCGCATCTGCGCCAAGCTGCATGCCAAGTACATGTGTCCACATTGCAACCAGCGCTTCTATTGGCATTCCAACTATGAGCGGCACGTTCAGGTGCTACATCCAGCGGAAAGTCAGCAGGAGCAAGAGAAGAGCAAGCTGCAGTGCAGCGAGTGCGATAAGATTTTCATATGGCCCAAGGATTTGACACGCCACAAGCGCATGCATCAGTCACAGGTGCAGTTCGAATGCGCCCACTGCGATCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCACACATGCGGATGCACGGCGAACAGCCGACGTCATCTATCggtgagcagctgcagcgcatGCCGATGGTCTTGAGCCAGCTCTGTCGCCCCAATGGCTGCAAGCAGATCAAGTGCATGATTTGCCTCTCTCAGCACACAAAGATCTCCGATTTGCGGACACATTTGATTAGCCATCAGTTGACGCTGTGTTTGGCCGAGGAGCGCGGCATCACAAACATTTGTCGTGATCTCTACCCGGAGCTGAACCCGCCGTTGGATCACCAGGCATTGACCAAACGCATTCAGCGTGATCTGGTCAATGGTCTGGAGCTAGAAAGATTCGTTTCGATAACCAACGAGGCGGTCATCGAACTTAGTTTGGACAGCAGCGAAACGGACACTGATTCGGATTGTGCAACAGAAACCGAACGGATCAGCAAGAAACGCTGTTACAGCTGTGAACTGTGCCAGGTGCAAGTAACGCGCAAACATCAGCTCTATGCCCACCAGCTGGAGCAGCACACGTGGCACCAAACGACCCACGTCTGTAGCCATTGCCAGGCGAGATTCGTCAATGAGCAGCTGCTGGAACATCACTATCGCACCCTCTGCCGCAATGCACAGCGGCGTTTCCTGTGTCGCAAGTGTCCGTTGCGCTTTCGCTGGCGCGATAATCTTAAGCTGCACAATGGTGTGGCGCATCAAGAGCAAGGGAATGTTGAACAGCACTCCAATGTGGACATTCAGTTGCGTATGCTGCCCGTGGTTAGCTACGACTGTGTCGAGTGCAAGCGTAGcttcaaaatgcaaaaggaTCTCACACGGCACACATTGATGCATGCTCAGGAGTCGAGCATATATCGGTGTCGCTGGTGCGCTCGCCGCTTCTATCGTGAGGCGAATCTGCTGCAGCACATCGAGCGACATGGCATAAGCGCCGACCAACTGCCCTATGCGGAGGCCCTACTCAATGCCTGCCGTCATCCGAACGGCCCGAAGTGCATCCAATGTCGCGTTTGTGATTTAACTTTTGGCAGCATTGCGGCACTGCGTTCGCATCTGCAATCGTCGCCCGTTGGGACTCATCATCCGATTGAGTCCATGGCGAACTATTCAATCACCAATCAGCTGGGCTACGAGCTGCACTTGGACGACTCCGAAACAGATGAGGAAGTTAAGCCAGCGGGGACTCCGGGGCATTATACGTGCGGGATGTGTCAGCTGCGCTGTGTGCGCAAGTTTGagctgcatcagcatcagcaggcCATGCATCGTCTGGAGCGCATTGCCGACGGCTGCGATCTGTGCATCTTCAAGAGCGTTTCACCCGATCTGATTGCCTATCATCGGCGTGTGCTGTGCGAGAACACGGAGAAGCAATTCAAGTGCTCGAAATGCAGCTACATGTTTATGTGGGAATCGAATCTGGTGCAGCACATGCAACTGCAGCATCCAAGCAGCGAGGAgtcgacaacaaaaacaaaatcactcATGGTCGTTCCCGACATTGCCAACGTTGAGTGCCAGATCTTCCAGTGTGGCCAGTGTCCTAGTAAATACAATCGCAAAGATCGCCTCACGGCCCATGTGAAAAAGTGTCACACAGCTGGCGCAACTGCGTCAACCAAGTTGCCAGCAGTTGCCAAGCAGCAGAAGAGTTTCCTCTGCGCCTTCTGCGGCAAGGCGGTGAGCTCGTCCTCCAATTTAATCATACACATACGTCGCCACACTGGAGAGAAGCCGTTTAAGTGTGATTACTGCGACATGGCCTTTCCGCGCTCTTCTGATCTCCAGTGCCATCGACGCACCCACACCGGCGAACGGCCCCACATCTGCACCGTCTGTAAGAAGGGTTTCGCTCGCTCCTacaagctgcagcagcatatGCGCATCCACAACGGTGAACGGCCCTACAAGTGCACCTTCTGCGACAAGAGCTTCACCCAGTCCAATGACCTGACCCTCCACATCCGACGTCACACGGGCGAGCGACCTTATCAGTGCAATACATGCGGCGAGCGATTCATTCAGGGCACGGCGCTCAAGAACCATCGACTGCAGAATCGCCACTATGAGACGGAAGTCGATCAATCAAAAGATGATTAA
Protein Sequence: MLPANVCRTCALQDDNLLALTTRSEKYTKKSICDMLHELTQNDPLLEHTDDKLPQHLCGQCLSQLEAAYTFVLQAREAQEQLLLQLRKGLQTQCLDETPIDISIEHIKMEADMDLYADTADTVDTKLEEKQGKQVALKCQVETDSDSSQENVKDFDFEVNTPQLRRSARRPKLSTESDESTSEKVKPAPVKRGRGRPARLAKRKTTTNEDGRHVCEVCGKTFSWYRDMQRHARIHFEQAGFVCEHCGKKFLRKDKYMTHLRSHKKQMVTDRLVLPRSIEWRYAERLYSSGRLMRVECKLCGLSCQRIQELREHLAIHVRIETLSNLSLDNDVIQEQFSDQLDLQQIKEQVCTEIAKGREQLENYGTVVNFYGYELYLSDSDDEEEDEELPAKYQCRRCDVNFARKHQFMHHTIEEHTDRSEPPLERCNICQIGFVCPKLLEQHQRTQCLNPLKRYSCENCPGKFIWLQNLKQHACCALKQDLQQELQHRHQEQQQAPHRQIQCCLCNEQPSSMAALRSHLLIHCDGHTDVDPDKQSAFFRTYYQDDGASSLSDIRTRIASDFDAQLYGKYFNACTDSGQELDFNDSDKEWSDAPALHSCAVCGESRIRLDQLLQHQQSQHFELAGRLPHVCLDCGLGYVAESLLQQHRRRICAKLHAKYMCPHCNQRFYWHSNYERHVQVLHPAESQQEQEKSKLQCSECDKIFIWPKDLTRHKRMHQSQVQFECAHCDRKFHRKDGLKSHMRMHGEQPTSSIGEQLQRMPMVLSQLCRPNGCKQIKCMICLSQHTKISDLRTHLISHQLTLCLAEERGITNICRDLYPELNPPLDHQALTKRIQRDLVNGLELERFVSITNEAVIELSLDSSETDTDSDCATETERISKKRCYSCELCQVQVTRKHQLYAHQLEQHTWHQTTHVCSHCQARFVNEQLLEHHYRTLCRNAQRRFLCRKCPLRFRWRDNLKLHNGVAHQEQGNVEQHSNVDIQLRMLPVVSYDCVECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYREANLLQHIERHGISADQLPYAEALLNACRHPNGPKCIQCRVCDLTFGSIAALRSHLQSSPVGTHHPIESMANYSITNQLGYELHLDDSETDEEVKPAGTPGHYTCGMCQLRCVRKFELHQHQQAMHRLERIADGCDLCIFKSVSPDLIAYHRRVLCENTEKQFKCSKCSYMFMWESNLVQHMQLQHPSSEESTTKTKSLMVVPDIANVECQIFQCGQCPSKYNRKDRLTAHVKKCHTAGATASTKLPAVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCKKGFARSYKLQQHMRIHNGERPYKCTFCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQNRHYETEVDQSKDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577186;
90% Identity: iTF_00552447;
80% Identity: -