Dmel009799.1
Basic Information
- Insect
- Drosophila melanogaster
- Gene Symbol
- -
- Assembly
- GCA_000001215.4
- Location
- JANZWZ010001362.1:270219-271942[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.0055 0.6 11.0 3.7 3 23 257 277 255 277 0.97 2 8 0.00023 0.025 15.3 0.7 1 23 283 308 283 308 0.94 3 8 0.0095 1 10.2 0.1 5 23 321 340 320 340 0.95 4 8 0.00012 0.013 16.2 2.2 1 23 352 374 352 374 0.97 5 8 8.5e-07 9.3e-05 23.0 0.1 1 23 381 403 381 403 0.98 6 8 0.0054 0.59 11.0 0.2 1 23 409 431 409 431 0.97 7 8 1.7 1.9e+02 3.1 3.9 1 19 437 455 437 457 0.95 8 8 0.022 2.4 9.1 4.3 2 23 463 484 462 484 0.96
Sequence Information
- Coding Sequence
- ATGAACGAGGGCAGGCAGTACTCGATCCACAGCCTGTGCAGGATCTGTCTGAACCACCTGCAGAACGACGCCGCCTACGATTTGTATCTGGTTCCAGGACTTTCGAAGAAGCTATGCTTCTGCACATCCCTGTCCGTGGAGCAAAACGACGGATTCCCGAAGAACCTGTGCACCCTGTGCTACACCAAGCTGAACGAGCTGCACGACTTTCAGAAACAGTGCGTCGATTCCGTGCAAAAGTTCCAGGATCTGGTGGCCAGCAATGTCTTTGCCTGCCAGAGCAGCTTCGACGTCTTCGATCCCAACGTTGCCGTGCAGGACTACCCGGCCGAGGAAGAGGACCACGTCAACTATGACCCGCTGCTGAACCACAAGATGGAGCTAATCGAGAACGAGGAGGATGTCTTCAAGATGCTGGAGCACGTCGACAAGGAGGCCGAGGAGGTGGAGAAGGAGGCCAAGGTGGAGGAGGATGACGGGGGCAACGTTTCCGTCAAGATGTTCGACGACGATTCCTCCATCGAGAGCGGCAATGACAACGACCACGATCTGGACTTCGAGCCAAATAGCAGCGATGATGACATTCCGCTGGCCCAGCGCATGAGGGGACCAGCTACCGGATCAGGACCCCAGCAGGACCGTTTTAGCAACCTAGACAAACCCAAGCCGAGGCCCCGGGGACGGCCCAAAAAGATAAAACCGCCTCCGCCAGAGGAGGAGGAGAAGCGCATTCCCATCGAGGAACGCCACCTGCACCGCATCATCGACTGCCACATTTGCCACCAGAAGTTCAAGAAGGCCATCCGCTACGAGGAGCACATGAAGTACCACAACGACCTGCTGCCCTTCCAATGCAAGGTGGAGACCTGCAAGAAAGGTTTCACTACCGCCAATGGGCTGCGCATTCACATCGACCACGCCCACACAGAGCTGTCCGAGGTTCACGCCTGCATCGCCGAGGGCTGCGGCAAGACCTTCCCGCGCGTCCGTCTGCTCACCTTCCACATGAAGAAGGTGCACGGTATCACCAAGGCGGCTGCCCCGCTTCGAGATTTCCCCTGCACAGAATGCGACACCGTATTCCGCTGCCCCACAGCACTCAAGAAGCACATGTATAAGCACACGGGCGAGGAGCTTCCGTATCCTTGCAATATCTGCGGCAAGCGTTTTGTAATCAATAGTGCTTTAAGGGATCACCTTATGCGGCACGCAGGCATCAAGAACCATGTGTGTCCGTACTGCGGGGTGGGCAAGACGACGCGCCAGGAATGGAACGCCCACATCCTCACGCACACCAAGGAGAAAAAGTTCAAGTGCCGACAGTGCGACCATGCCTCGCACAACAAACAGGCGTTGTCCAATCATTCACACGGGGAGAAGTGCTGCGAGTGCAAGATCTGCGGCAAGATATTCCTCTGCGAGAAGAGCCTCACCAAGCATTTGAAGACGCACGAGAAAAGGGATCTGCCGCCGGCGGAGCCCACTTCGCCAGCAGCTTAA
- Protein Sequence
- MNEGRQYSIHSLCRICLNHLQNDAAYDLYLVPGLSKKLCFCTSLSVEQNDGFPKNLCTLCYTKLNELHDFQKQCVDSVQKFQDLVASNVFACQSSFDVFDPNVAVQDYPAEEEDHVNYDPLLNHKMELIENEEDVFKMLEHVDKEAEEVEKEAKVEEDDGGNVSVKMFDDDSSIESGNDNDHDLDFEPNSSDDDIPLAQRMRGPATGSGPQQDRFSNLDKPKPRPRGRPKKIKPPPPEEEEKRIPIEERHLHRIIDCHICHQKFKKAIRYEEHMKYHNDLLPFQCKVETCKKGFTTANGLRIHIDHAHTELSEVHACIAEGCGKTFPRVRLLTFHMKKVHGITKAAAPLRDFPCTECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHSHGEKCCECKICGKIFLCEKSLTKHLKTHEKRDLPPAEPTSPAA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -