Dmel015541.1
Basic Information
- Insect
- Drosophila melanogaster
- Gene Symbol
- -
- Assembly
- GCA_000001215.4
- Location
- JANZWZ010000683.1:108197-111256[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 6.6e-06 0.00072 20.2 4.2 1 23 194 217 194 217 0.97 2 13 0.0003 0.033 15.0 0.2 1 23 224 246 224 246 0.97 3 13 0.14 15 6.5 0.1 2 23 278 299 277 299 0.94 4 13 5e-05 0.0054 17.4 2.1 1 23 389 412 389 412 0.97 5 13 0.17 18 6.3 0.6 1 19 419 437 419 440 0.93 6 13 0.045 5 8.1 6.4 1 23 449 471 449 471 0.95 7 13 0.012 1.3 9.9 0.2 1 23 478 500 478 500 0.93 8 13 0.00026 0.029 15.1 2.4 2 23 508 529 507 529 0.96 9 13 0.04 4.3 8.3 0.2 3 21 557 575 556 576 0.95 10 13 2.1 2.2e+02 2.9 0.3 10 23 621 635 619 635 0.90 11 13 0.059 6.5 7.7 0.4 1 23 672 695 672 695 0.93 12 13 0.047 5.2 8.0 0.3 5 23 715 734 714 734 0.93 13 13 4.9 5.4e+02 1.7 0.3 2 16 749 763 748 776 0.77
Sequence Information
- Coding Sequence
- ATGAAGCTGCCGGTGATTTGTCGCACGTGCGACTCCACGGACACCGACAACCTTCTGAAGCTGGCCACGCCCTCGAAAAAGTATCCGGACAAGTTGCTTTCGGAGATTTTATGCGAGCTAACCGAAATCAATCTGGATGCAACTGTGGATGCACCAAAAAAATTAATGGGTGCCTATTGCTATGTGAAGCAGGCGCTGGCCGCCAACGAACTTCTAATGAAGCATCTAAAGAACGGTGCTGCTCCAACGTCAACCGACTGTCTGCAGGAGGCGCCGATGGAGCTGTGTGCTGAGCAGCATGTGGAAGTCAAGCTGGAGACTGAGGATGAGGACTGTGGCGAAAATGATGTTACTATCACTTGTTCCGAACTACCGGAACCGGACGAAACGGACATGGAGAGCAAAAAGTCGGTGGACCCACTGACCATGATTGAAACGGTGAAGCTGGAAATGGAACCCAGAAGCGTGGAGAAGCCAGCGTATGACGATCCCACATCGGACTTTGAAGACGAAGACTCCCTGGATAATTTGCCACTGTATAATCGCATTCAAAAGTGGAAAACAGGAAGAAAGTCTGTATATAAATGTCACGACTGCCCTAGGAGTTTTAAACGATTCGACTTCTTGAAACGCCATGAAATGCGCGTCCATAAGCCAGAAACTCGATTATATGACTGCTCCCTTTGCATTCGCAAGTTCAGCCGCAGCGAAGCCCTCGAAGCACACCTAAAAATTCACCGGAATTCAAAACGATCGGCCAACATTAGCGAGCACAAGAAGGCCAAGGCTGTGGATTTGAATCTCTGCAAACCGCATGGCTACAAGCTGATTGAGTGCATGATCTGTCAGAGCCAATACAACAAGATTGCTGATCTGCGCCGGCATTTGGAGGAGCACCCCGATATTGTTAGCCTGTGCGGTCGGCCAAATATGGAGCCCCATGAGCTGGCAGAGCTGTTTTATCCCGATTCAAAGGACCTCAGTGAGGAGCAGTTAATCAACTTGATTCGCAAGGATCTAGCGGCGGGTATCTATCAGCGTTTCTATTCGATAACGAACCAAAGTGGCTACGAAATGGATCTGGACAGCTCGGAGACGGACAGCGACCTGGACGGAGATCACGATGACCAGCACAAGAGGCGAAAGAAGTCGCGCAAAGCCACCTACAGCTGCGAGCTGTGCCAGCAAAAGTTCCCGCGAAAATATCAGCTTTATGACCATCAGCGACAAAGTCACAGTTGGTCAGACGCTCCTCACGTCTGCGGGCGATGTGATGGACGTTTTGTGAGTCTGCAGCTGCTGCGCCACCACAACGAGTCGCAGTGTAGGAATGCACAAAAGCGATTTCTCTGCCACAAATGCCCGCTACGCTTTCGCTGGAAACACAACCTGAAAACACACTTCCGCGAACACAGGATTACAAATCAAACGTTTGAATGTTCCGAGTGCAAACGGGTCTTTGATAAAGAAATCCTCACCGTTCACCTGCTTAGCGTACATGCGGAGGAATCCAAGCTGATTCCCTGCCAGTGGTGCAGTCGCAAATTCTATCGGCACGACTACTTGGTAAAACACTTGAAGCGACACGGTTTGAAAGAGCATGACATTCCCTTGGCAGAAACATTGATTGCTGCCACCTCGCGGCAAACGGAGCGAAGCGCATTACTTTGCCGCATGTGCAATCTGCATTTCGAGCGTATTGTTGATCTGCGAGCCCATATCCAGTTGGAGCTTAAGCTATCCCTGTCGCTACACCAGAGCTACGACTCCCCGCATAATTATTCAATAACAAACGAATCTGGCTTTGAGCTGCAGCTGGAGGATTCGGAAACCGAGAGACGAGATGCAGCCCGCGTGCAGTGCAAGCGGAAGTTCGAAATGATCCAGCATCAGCGGACGATGCATCGCTTTGACAAAATGCCACACGAATGCGACGACTGCATCTTTAAATGTGTCTCCAAGAGCATTATGGACCACCACCGGCAAGGTCAGTGTAGTAGTACAGAAAAGAAGCATGCATGTGGCAAGTGTTCCTACAAGTTTATGTGGCCAGAGAACCTAGAGCAGCACATTCTCCTGCAACACAGCAAGTCTTCCGTCAGCAATCCGACTGGCGACAGACACACGCAAGGGACCGTGTCCACCTGCGATCGCACGTACCAGATGAAGTCGCGCCTGAACAATCATATTCGCGATGTGCACATTAACGGCGACCGCAAGCGCAAGGAGGCAATTaagcgcttcctctgctccctgtgcggaatggagacgagatcagccgccgctcttagcagcacgctggagaagcatCGGTTGATGCGGCGTCACTTCGACGAGGTGGAAGCGTGGCTGAGACGCCAAAAGTAA
- Protein Sequence
- MKLPVICRTCDSTDTDNLLKLATPSKKYPDKLLSEILCELTEINLDATVDAPKKLMGAYCYVKQALAANELLMKHLKNGAAPTSTDCLQEAPMELCAEQHVEVKLETEDEDCGENDVTITCSELPEPDETDMESKKSVDPLTMIETVKLEMEPRSVEKPAYDDPTSDFEDEDSLDNLPLYNRIQKWKTGRKSVYKCHDCPRSFKRFDFLKRHEMRVHKPETRLYDCSLCIRKFSRSEALEAHLKIHRNSKRSANISEHKKAKAVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPDIVSLCGRPNMEPHELAELFYPDSKDLSEEQLINLIRKDLAAGIYQRFYSITNQSGYEMDLDSSETDSDLDGDHDDQHKRRKKSRKATYSCELCQQKFPRKYQLYDHQRQSHSWSDAPHVCGRCDGRFVSLQLLRHHNESQCRNAQKRFLCHKCPLRFRWKHNLKTHFREHRITNQTFECSECKRVFDKEILTVHLLSVHAEESKLIPCQWCSRKFYRHDYLVKHLKRHGLKEHDIPLAETLIAATSRQTERSALLCRMCNLHFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGFELQLEDSETERRDAARVQCKRKFEMIQHQRTMHRFDKMPHECDDCIFKCVSKSIMDHHRQGQCSSTEKKHACGKCSYKFMWPENLEQHILLQHSKSSVSNPTGDRHTQGTVSTCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKRFLCSLCGMETRSAAALSSTLEKHRLMRRHFDEVEAWLRRQK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -