Basic Information

Insect: Drosophila melanogaster
Gene Symbol: grau
Assembly: GCA_000001215.4
Location: JANZWZ010000740.1:633393-635367[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 6.9e-07 7.6e-05 23.3 0.4 2 23 297 318 296 319 0.94

2 8 1.5e-06 0.00017 22.2 0.9 1 23 327 349 327 349 0.96

3 8 0.14 15 6.6 1.8 1 23 357 382 357 382 0.89

4 8 0.00091 0.099 13.4 0.9 3 23 389 409 388 409 0.97

5 8 0.048 5.2 8.0 0.2 2 23 418 441 417 441 0.86

6 8 0.00011 0.012 16.3 0.5 1 23 448 471 448 471 0.94

7 8 5.4e-06 0.00059 20.4 0.8 1 23 476 498 476 498 0.97

8 8 5.4e-05 0.0059 17.3 3.8 1 23 504 527 504 527 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	6.9e-07	7.6e-05	23.3	0.4	2	23	297	318	296	319	0.94
2	8	1.5e-06	0.00017	22.2	0.9	1	23	327	349	327	349	0.96
3	8	0.14	15	6.6	1.8	1	23	357	382	357	382	0.89
4	8	0.00091	0.099	13.4	0.9	3	23	389	409	388	409	0.97
5	8	0.048	5.2	8.0	0.2	2	23	418	441	417	441	0.86
6	8	0.00011	0.012	16.3	0.5	1	23	448	471	448	471	0.94
7	8	5.4e-06	0.00059	20.4	0.8	1	23	476	498	476	498	0.97
8	8	5.4e-05	0.0059	17.3	3.8	1	23	504	527	504	527	0.98

Sequence Information

Coding Sequence: ATGGATATCTGCCGCCTCTGTTTACGCGGAGTGAGCGGCGCCCAGATGTGTCTACAGATCTTCGATGTGGACTCGGGCGAGAGCAAGGTGGCGGAGGTGCTGCGCCAACATTTCTGGTTCGAGGTACTGCCCAACGACGAGATATCCAAGGTTATTTGCAACGTCTGCTGGACGCAGGTGTCCGAGTTCCATCAGTTCTACGTGTCCATACAGGAGGCCCAGGTGATATACGCCACCACCTCCAAGTTCAAGCAGGATCCGGAGATGGTGAACACCTCCTGGCCGGAGGAGGTGCTCATGCCGGCCGACGTCCTTGCCGTCGACAACGATGTCGGTGCGCAGATAAATGTGAATCCCCTGGACGAGTTAGACCTTAGCCAACCCATGTCCCCGGAAGACAGCAAGGTGGGCATCAAAACAGAGCGACAGTCACCCGACATGGAACTCCTCTTTGAGGATGCCAACAATGAACAGGATGAGGACTACGAGGACGACGAGGATGATGACACCGACGACCTGATCGTGACCCGGAGTGGACGCAAACGTAAACGGGACGTGGCCAAGCCGGCTAAAACGAAAAGAGGAACGGTGTCGGTGGGCAGAAAGGGGAAGGAGAAGATGGTGGTCAAGCGGGGACCGCCCAAGAGGATATTCAAGATGGAACGCCTGCCGCCGTTTTGCAAAGAGGACGAGGAACTGATCAAGCGCTACATAGTCATGGGCTGCGAGCTGTGCATATTCTTGGCCGAGGACTTCGACGGCATCCGCGAGCACTTCAAGGACAAGCATCCGGACGAGCGGCCCTACATCAAGTGCTGCGGACGCAAGCTCAACAAGCGCTGCCTCATTCAGGAGCATGCGAGGAGGCATGAGAATCCCGAGTACATCAAATGCAAGGACTGCGGAAAGGTGTTCGTCAATTCCAGCGTATTGCGTGCCCACTGGCTGGTCCACCATGTTCCAGACGAGGAGTGCGACTTCCAGTGCGAGGACTGCGGCAAACGCTTCTCGCGACGCAACCTGCTCGAACTGCACAAGGGCTCCCATGTGCCCGTAAATGAGCGCAAGTTCATCTGCCCGCAGTGCCCCAAACACAATGCTTTTGCCACGGAGTACCACATGCAGGTCCATATCAGCATGCAGCACCGCAAGGCGGCCAATATCTGCCATGTGTGCGGCAAGAAGATCAAGGACAAGGCTGTCTTCGAAAAGCACGTTCGCCTGCACTTCGAGGAGAGCGGACCACGGATCAAGTGCCCGCGTCCTGACTGCGAGAGCTGGCTGAAGGACGAGGACAATCTTAAGCAGCATTTGAGGCGCCACAACGACGAGGGCAAGCTGTTTATCTGCTCAGAGTGTGGCAAAAGCTGCAAGAACTCCCGCGCGCTGATTGGTCATAGCGCTACTCCCCACTCGAATGTGATCTACACCTGCGAGCAGTGTGGCAAAACCTTCAAGAAGGACATCAGCCTTAAGgagcatatggcgcagcacactggcgagccactctacaagtgtcccttctgtccccgcaccttcaactccaacgccaacatgcactcccacaagaagaaaatgcatccggtggagtgggacatctggcgaaagaccaagaCCGCTATTGCCAATGACTATTCGGGTTAG
Protein Sequence: MDICRLCLRGVSGAQMCLQIFDVDSGESKVAEVLRQHFWFEVLPNDEISKVICNVCWTQVSEFHQFYVSIQEAQVIYATTSKFKQDPEMVNTSWPEEVLMPADVLAVDNDVGAQINVNPLDELDLSQPMSPEDSKVGIKTERQSPDMELLFEDANNEQDEDYEDDEDDDTDDLIVTRSGRKRKRDVAKPAKTKRGTVSVGRKGKEKMVVKRGPPKRIFKMERLPPFCKEDEELIKRYIVMGCELCIFLAEDFDGIREHFKDKHPDERPYIKCCGRKLNKRCLIQEHARRHENPEYIKCKDCGKVFVNSSVLRAHWLVHHVPDEECDFQCEDCGKRFSRRNLLELHKGSHVPVNERKFICPQCPKHNAFATEYHMQVHISMQHRKAANICHVCGKKIKDKAVFEKHVRLHFEESGPRIKCPRPDCESWLKDEDNLKQHLRRHNDEGKLFICSECGKSCKNSRALIGHSATPHSNVIYTCEQCGKTFKKDISLKEHMAQHTGEPLYKCPFCPRTFNSNANMHSHKKKMHPVEWDIWRKTKTAIANDYSG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00494594;
90% Identity: iTF_00531851;
80% Identity: -