Basic Information

Insect: Drosophila melanocephala
Gene Symbol: -
Assembly: GCA_037043625.1
Location: JBAMBD010000007.1:174332-175548[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.001 0.069 13.6 0.0 3 23 198 219 196 219 0.96

2 6 8.8e-06 0.00058 20.1 1.1 1 23 226 249 226 249 0.94

3 6 0.0002 0.013 15.8 0.9 2 23 270 291 269 291 0.96

4 6 0.011 0.7 10.4 1.1 1 23 297 319 297 319 0.96

5 6 0.00011 0.0071 16.7 2.0 1 23 326 349 326 349 0.98

6 6 0.003 0.2 12.1 4.2 1 23 355 377 355 377 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.001	0.069	13.6	0.0	3	23	198	219	196	219	0.96
2	6	8.8e-06	0.00058	20.1	1.1	1	23	226	249	226	249	0.94
3	6	0.0002	0.013	15.8	0.9	2	23	270	291	269	291	0.96
4	6	0.011	0.7	10.4	1.1	1	23	297	319	297	319	0.96
5	6	0.00011	0.0071	16.7	2.0	1	23	326	349	326	349	0.98
6	6	0.003	0.2	12.1	4.2	1	23	355	377	355	377	0.98

Sequence Information

Coding Sequence: ATGTTAACTTTTGCCAATATTTCCCAATTATGTCGCATTTGCCTGCGCCATCTGCGTCAGATTAAtgaacagcaccagcaacaccaacagcgcAACAAATCCAGCTACAACCCGAAAGCGCTGCCCCATttggcaaaaatgttgaatcACTTTTTTGCCATTGACGTATTTCAGCAGCCAGAGACATATCCACAAGACATATGTGCATTGTGCTACAATGCCATCGAATACTTTCAGCAGCTCTGCAACGTCGCCGAGCAGAGCAACGAGATGCTGATGCGCCTCACCATAACCCTGGCCGTTGATCAGCCAAAGAGGACTGAAGCTGATGTTGATGTCCATGTTGACGTTAATGCTGACGATCACTCGTTGTCGCTCGTGAAAGCAGAGCCGGCGGAAGACGAAACACAGCATCACCAAGATTACAATGCTGACGCTATCGCTGACGCTGACGTGGATGCCaacggcgatggcgatggcgatgtcgATACCGATGCGGATGCGGACAATGTAAACGACAACAATGAGAGCCTAGAGGCGAATAATGATGAGGCAGCGGCTGCAGCGGCCAGCAAGCGAAAGTTGCTTGCTTGCGAGCAATGCGGCAAGCAGGTGTACAAGCTGCCCTATCTGGAGGCGCACATACGGAGCGTGCACGAGGGCCACCCGAAGCCGTTTCTATGCCGAAATTGTGATAAGGCCTTCACTCGATATGAGCAACTGCGCTCACATGTGCGCAATGTGCATCCGGCTGTTGCGGCtgcgacaacaagaacaacatcatCGATCAGCGAGGAGCTAGAACTATACTGTGAGCAGTGTAATCGCAGATATAGTACGAAAAATGCACTCGGCGAGCATCTGAAGCGTCACGCACAGGAAAAGCCGCACATTTGCGAGCACTGCGGGGTCGCGAAGGTGACACGCACCGAACTGCTCACCCATCTGCGCATCCACAATCCCGACTGGGAGAAGTTCAAATGCAAGCAATGTCCGCAACTCTTCCGTCACAAGAGCGCCATCAGCCGGCACGTTCGCGTCGTACACGAAGGGCAGCGGCGATTCCAGTGCGGTCATTGTCAGAAGCGATTCGGCACCCATGCCTCTCAGGTGCGACACGAGCGCCTCCACATTGAAACATTTTAA
Protein Sequence: MLTFANISQLCRICLRHLRQINEQHQQHQQRNKSSYNPKALPHLAKMLNHFFAIDVFQQPETYPQDICALCYNAIEYFQQLCNVAEQSNEMLMRLTITLAVDQPKRTEADVDVHVDVNADDHSLSLVKAEPAEDETQHHQDYNADAIADADVDANGDGDGDVDTDADADNVNDNNESLEANNDEAAAAAASKRKLLACEQCGKQVYKLPYLEAHIRSVHEGHPKPFLCRNCDKAFTRYEQLRSHVRNVHPAVAAATTRTTSSISEELELYCEQCNRRYSTKNALGEHLKRHAQEKPHICEHCGVAKVTRTELLTHLRIHNPDWEKFKCKQCPQLFRHKSAISRHVRVVHEGQRRFQCGHCQKRFGTHASQVRHERLHIETF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00497677;
90% Identity: iTF_00549095;
80% Identity: iTF_00498409;