Basic Information

Insect: Drosophila melanocephala
Gene Symbol: HIVEP2
Assembly: GCA_037043625.1
Location: JBAMBD010000606.1:41870-50925[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0015 0.096 13.1 0.4 2 23 197 218 197 218 0.98

2 8 0.00022 0.015 15.7 3.2 1 21 224 244 224 248 0.90

3 8 0.0088 0.58 10.6 0.4 1 19 897 915 897 918 0.93

4 8 2.7e-06 0.00018 21.7 2.0 1 23 1651 1673 1651 1673 0.99

5 8 1.1e-05 0.00076 19.7 5.3 1 23 1679 1703 1679 1703 0.92

6 8 0.00052 0.034 14.5 3.5 2 23 2197 2218 2197 2218 0.97

7 8 0.00078 0.052 14.0 1.2 1 23 2224 2248 2224 2248 0.91

8 8 0.0025 0.17 12.4 2.7 1 23 2269 2293 2269 2293 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0015	0.096	13.1	0.4	2	23	197	218	197	218	0.98
2	8	0.00022	0.015	15.7	3.2	1	21	224	244	224	248	0.90
3	8	0.0088	0.58	10.6	0.4	1	19	897	915	897	918	0.93
4	8	2.7e-06	0.00018	21.7	2.0	1	23	1651	1673	1651	1673	0.99
5	8	1.1e-05	0.00076	19.7	5.3	1	23	1679	1703	1679	1703	0.92
6	8	0.00052	0.034	14.5	3.5	2	23	2197	2218	2197	2218	0.97
7	8	0.00078	0.052	14.0	1.2	1	23	2224	2248	2224	2248	0.91
8	8	0.0025	0.17	12.4	2.7	1	23	2269	2293	2269	2293	0.92

Sequence Information

Coding Sequence: ATGACGCCACAGCAGGTGGCAAGCAGCGCAGCGAgcaatgtggcagcaacaacaacaacaacaacagcagcaacaacaataccagcCACAGccaacaccaccagcaacaataacaacaaccagaacaacaacaacaacaacaacaataataacaacaacagcagcagcaacaaccacaacaacaacaacaacagcagcagcgaggatccaacaacagcagcagcaacaattgtcgATGGCTGGACGAGCTCAACCAATTTGCgttatttgcacaaaaagtTTAAGCGGCTGGCGAGCACCACCGAACCAGAGTCGGTGGATGCAATGGCAGCGGTGCGCACCACATCGCTGTCATCGAATAGCTCGTTGTCGCCACCGCTGCCAGTGGCCGCAGCACCGCTGCTCAATGGACATGTGACGGTGAAGcatcagcaacaaacgcaaccaacgccagcagcaacagcagccgcaacaacaacaacaacaacagcatcagcagcaccagcagcaacagcagcaacaacaataatacaaacaccaccagcaacagttgcagttgcaggaTTGGGCGAGAAAACTAGTCGCCCCAAGTGCCCCTATTGCAATCTGATCTGTGCAAAGCCATCGGTGCTGGAGAAGCACATTCGTGCCCATACCAATGAGCGACCGTATCCGTGCAACAACTGTGGCATCGCCTTCAAAACGAAGAGCAACCTGTACAAACACTGCCGTTCCCGTTCCCATCTGGCGCGCATGCGTGGCCTCGACGTGCCAGCCAATGAGACGGACGGTCTGTCCGACCAGGACGGCGACGGAGAgctgagcaacagcagctccgAGCTACTAAGCGTCGAAGTTTTGAGTCGCACTGATTCGCCTTATGATGAGGCAATGGCCTCGCCGACGCCATCACCATCGACGCTGTCGGCGGCGAAGAGTACGTatctgcagcagccgcaactgcaacagcatatgctgcaacagttgccgctgGGCTCACCAGCAGCCGGAACACTCCCGCCCGCCCCGCCCGCCGACTGGCTGCACTCGGCGACCGCTCAGCATCGCCAGTCGCTCGACTACAAGCCATACAAGCCCAAGTTTCACAATGCATCCCTCTATGCGCCCGGCACCCTCAaggaagcaacagcagcaacagcagcagcagcagcaacagcagcaacagcagcagcagcgcagcaacagcaacagcaacagcagcagcagcaacaaccatcGCTGGCGCATCCAACGATCTCGCCCAGCACCCAGTTGAAGCTCAACAATCACATCAATTCGcatcagttgcagctgcagctgcagcaccagcaccaacagcagcagcagcagcagcatttgcacGCCCAGCAAtccttgctgctggctgctgcagcaaccaATCCGGTTGCATTGTCTGCattgccaccgccgccgccgggCGTTTATTATTTGGGACAGCCGCAGTATTATAatccaactgcagctgcaatgcATCAGCATGCGCTGGCCATTCAGCagatgcagttgcagcagcactttcagctgcaacaacaacagcagcagcagcaacagcagcatcaaaatcaccaacagcagcaacagcaacagcaacagcagcaacagcagcagcatcaccaacagcagcaacagcagcagcaacactcgCCGTTGCTGAAggcgccacagcagcaacagcagcagCAGCTGTTGCGCTCCACTAGccaacaacaggcagcagtgattgcaacaacagcagcgctgccagcaCCAGCCACACCCAACCCGCCAACCAATCTGACCAGCTTTGCCAGCTCAAGCGGCGGCATGCAAGTGAATGTGGAAAAGGTGCAGGAGCACATCTCCAAGCTGATCTCACAGAACGAGGCGATTGTGGAGAACAAGGAGATACTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGTTCGCGCAGCttcaacaatgccaacaacaacaacaacaacaatagcaacaacagcagcaacatcaccaacagcagcagtataCCAGCAACAGCGcacgccaacagcaacagtaacaacaacagcaatcagcaGCTGGGCGAGACGAAAGTGAACCTGGCACAGGCCATAgtacaaaaacagcagcaacagcagcatatgcagcaacagttgcaacagcagcaacaataccaATTAtacttgcaacagcaacagcaacaacaactggagcCGCCTGTGAATGGTCTGCTCAaacggagcagcagcagctctgcAAGCAGTACAGCCAGCAGCGGCTATGCCAGCTTTAAGAGCACAGCGACCTCAACACAAGCCGCCGCAACCACTGTAAATGTgaaacagttgcaacagttgccgccgccgccatcgccgttgccgttgcaacagttgcagtatCGTCAGGATCCGTCAACGCCAGTGCCcaagctggagcagcagcagcagcagcagttgcagttgcagcaacccCTGCCACTGAATTTGTCTGCCAAGCCCAAGCCGTCGCTAGCAATGCCAGCAAAACcaacgccaacagcaacagcagccgcatcagcaacaacaactgttgttgccaagagcacaacaacaacggcgccagcagcagcaccgaaTATATCGATAATCAAGAATCTGCTGTTGAATGCACGTGGTTTGGCAGTGCCAATTGGCGAGGGCGATGATGCCGTCTACTCGTGCCCCATTTGCGCCAGTAAGTTTCGCAGCGCGGACGAGCTGAAGCACCACAACAGCACCTATTGCCAGGATGCGAACAGCAGTGCACCGATCAGTCCAGCCTCATCGCCGAGCACCAAATACTTTCGCTCCAATTCCATATCGTTTAGCCTGCCAGAGCTCCAGTCGCACATGGCCAACTCGAAGAATCCGTTGTCGCTGGCCAAGCTCGCCAAGGTTGCCTGCAgctatcaacagcagcagcagcagcagcagcagcagcaccacataaacagtagcagcagcagcatcaatcgcaacagcagcaacaatcacataccagcaacggcagcaacagctgtcgTAATCCCGCCCAGCATTGATGCCACCAGCGTTGCCTTGCGTTTTGTGGACGCACCGCTGCCATCGCCGGGTCCGCTGCTTGGCAAGACACCGCTGGTGGATTATGCGGCGCCACGCAAAGCGCCCGATGCCCAGGTGGTCATCACGAAAATGCACGAGGATCGCCTGGAGAACATCATCGTTGAGGCGCCATCGAAACGGCTCAAGCTGAGCAGTGGCGAGACATCGTTCACGCTGCCATCTGTCGTCGATATGCTCTTTGCTGGCAATCCAGAGTTGCAGTTCACTTGCAAGGAGGAGCGTTTGCGTCGCTTTACCTCATCCGGCGGCACCATGATACCCATTTCGGAGTGTCCCGAGCTGGACAAGAGTCCCAAAATGATACGCACTCCTCTGTTGTCCGGCGGCAGTTTCCAGGAGATGTCGCCGCGTCTCAGCGACATCAAGGAGCGCAAACTACtcgctgccaacaacaacaacaacaacaataacaacaacaataataataataataataataatggtttCCTGCTCAGCGCCTCCAACACGTCGCATCATTTCCAATTCCCACCCATCAATTCGATAACCGCCTTCAATCCGCTGACCCTGCCACCgatgtgcaacagcagcagcagcaacattgtgGATAAAGCGATACCCTATGTGCCTGGGATACCTGGTCCGGGCAGCTTATCGTTGCTGCCACCgccactgcagctgcagcgtgGACGCAGCCCCAATCGCAAACAGCCCAGTCCCAATACGAATGCCAATCTCAATATCAATCTCAATCCGCTGCTGGCAGCCGAGGGCCCACTCAAGGCACTCTCGCCCTTCGGTGGCGTACAGAATTTGCCCAGCGAATTCAGTCGCCAACCACCAACGCCAGCGCAACGCAATGCGCTCCAATggacgaacagcagcagcagcagcagcagcaataagcTGCCAGTGATTGTCGCTGACGGCACGCTGGCCAAGAAGCCACCATTCAATTTTCTACGCATGGCGGACAATGTGAAGAGCTCCGCtgtgcaggagcagcagcaacagcaacagcaacagccacagccccTGGCAATGGGTATGCTGGAGGTGCGTCACTTTAATTTCGATAATGTGAACAAATCGCAGGAGGTGCTGGCGCCGCTGCACGTCGACACGCCCGATgaggcagccgcagcagcagtagcagcagcaatcaaaacaacgacaaccactGCAATTCTAGTAGCGGCCTCAACAACCGCAACGAGCAGTGCCAAGTCGAAATTCTTGCGACCCACCAGTCTGCCCCTGAAGCCGGGCACCTTTACGCCAAAGCGACATCATGGGATCACACCGACTGCCAATACACTGCCCCTCATCTCACCGGAAACCCCGAGACCGTCCAAGTCGTGCGTGCAACTCTATCTGAATGGCCATGCGTACACCTATCTGGGACTCAAGTGCAGCACCAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCCTCGTATGTGGCGGGCATGCACAAGCTGTCCATGTACAGTGTGTGGCAGGTGTGCGAGGAGAATCAGCCGCATCCGCTCGGTTTCAAGCCCAAACAGGTGATGGCCCTGTACGATTCCAGGCAAAAGATGCTCGGCACTGGCTGCACCACAGCAATGGCTGGTGCTGGCAAACTGCAGTACTCCGTCTTCAGTTCACAGGAAACGGTTAGCACGTGCTCCACGACGGCCAACGGGCAGAGCAAGTTCTACCAGCACCAGTTGAAGCAGCCGCCGTCAATTGGCGCACTCAGCGAGGCGAATGTGGCAGCCAAGGCCAGCGAGGAGGCTGCGGCCAAGAAGCTGGAAACGGGACAACTATTGGTCGGTGGCTACGAGTCGCATGAGGATTACACGTACATTCGTGGACGCGGGCGTGGTCGCTACGTCTGCTCCGAGTGTGGCATACGTTGCAAGAAGCCATCCATGCTCAAGAAGCATATACGCACCCACACCGATGTGCGTCCATTTACCTGCAGTCACTGCAATTTCAGCTTCAAGACCAAGGGCAATCTCACCAAGCACATGCAGTCGAAGACGCACTTCAAGAAGTGCATCGAGCTGGGCATCAATCCGGGCCCGATGCCCGCCGACGGCGAATTCCTTGATGTCGATGACTTTGATCAGCAATCGTCGACATCGGCGGGCGGACGCACCTCCTCCATGGCCGGTGAATCCGATTCGGATGACTACAGCGACAACGAGTCCGAGAGCAGTGACACCGACGAGTCCAAGTCGCGGATGAAGGAGCATGAGGCGGCACGGGgtctgctgtcgctgtcgatGACGCCACCGATACCGCAGAGTGTTTCACCGTATCCGCCACTGGTCCAGGATACGCCGGCTGCCAGTCCAGCGAACAGCATTGGCTCCTCGGCTGGCAGCGCAGCTGGCAGCGGTTCGCAGCCGAAGCGACAGGTTTGCTCGTTTACGTCGCCCAAGCCGCCGTTTGACTACCAGAAGCAGGAACAGTATTACTCCAATCCCGAGGAGTCCAAACCCAAGCGCGGTGTGCCCAACGACGAGAGCAGCGCGCCCATGGATCTGACCAAGCCACGTCCAATGCCCAGCATTTCAGTGGCGGCCTCGTCGCCCGTCGCCGACCAGATGCAGGCGCAGACACCCAAATCGCAGGCCCAGCAGATGCGCGACGTAATCTTTGGTGCGGGCAACAACGAATGCGGCTTCATGAAGACCCTAATCTCCGTCTCCGACAAGGTGCGCATCTCTGCCGAAATTGAGGAGCAGGCGAAGCGCGAAAGCGAGGGCGAAGATGTCCTCCTGCAGACGTACATCAAGGAGCAGGCGCTGCAGCATGCCAAAATGAAGCAGAGCCAATTCAGTCGCAGCTACCTGgtcacttccacttccaccaCCAACTCGAactgcatcagcagctgcagctccaacTCTACCACGACCAGTGTTAGCATTAGCTGTGTTGTTACCACGCCCATTGTCAATAGCAAGCCACAGTTGAACATCGCGGAGCTGCCCAGCATTGAGGTGCACGAGGTGAAGACACCAGAGTCGCCAACGCCATCGTCGGCACTTGTCAAATCCGCCGAGGAGAGCGAGGAAAGCGAAACGCAATCGGACCAGGAGAAGCCAAGCATAGCAGCAACGTCCATTCCTGTGCCAGTAACCGTCTCTGTTTCAGTTGCTGTGCCCGTTTCCAGCTCCAAGTCGAGTGCAGAGATTCAGCAGCCGCACAATGCCAATTTGCCTGCTGCAGTGCAGCAGCCAGATGCCACCGATTTTAGTGGCgtactcagcagcagcaacagcagcagcagcaacaaaaatagcaacagcagcagcggcagcagtggaTCAACTGCACCCACACGTATTGTGGTCGTCGGTGAGGATGGCTTCAAAACGACACCAACCAGCGGCAGCAACGAATTGCAGTCTGGCGgcgcaacaacagctgcaacagcagccgcaacagcaggtGCAACGTATACGAATCGTGTggtgccaccgccaccgccgccaatAGCGAGTGATGCGCGACCCACGTGCACCGTGTGCAACAAGACGTTCCAGCGAACGCATCAGCTGTCGCTGCACATGAACATCCACTACATGGAGCGGAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGCACCCAGGGTCATCTGCAGAAGCACGAGAGGAGCGAGGCGCACCGCAACAAAGTGATGATGACATCAACGTTCGGTGTGCCAACCACATCCAATCCGCGTCCCTTCGAGTGCACCGATTGCAAGATTGCGTTTCGCATCCACGGCCATCTGGCCAAGCATCTGCGCTCCAAGACACACGTCCAGAAGTTGGAGTGCCTGCAGAAGTTGCCGTTTGGCACCTATGCCGAGATCGAACGGGCTGGCATCAGTCTGACGGAGATCGATACCAGCGACTGTGAGAATTCGCTCATCTCGCTCAAGCTGCTGGCGCAGAAGCTGGTCGAGAAGGATCCGAACAAGCTGAGCGGCTACACAACGCCGTCGGGCATGCTGCAGCTATCGGCGGATGCACCTGCTGCCGGCCAGGACAGCGCCTCCGAGGATGGCTTCAGTGCGGCGAACAGTGCCGCCGCCTCGGCCATTGCCTCGCTGGACAACGACAGTGCGGGCAACACACCGAAGCGTGCCAGCTCCATGTCCGAGGATGAGACCCTCACCAACGGACTCGGCctcagtcacagtcacagccaTGGCCACAGTCTGAAGCGACGTCTGCAGAACAGCAGCTTCAGCAGCAATGGCGACGAGAGCGACAATCCAACGGATACCACTGGCAGtggcggcagtggcagcagcgagAAGCGTGCCAGAAGCAACACAAATGAAATCATCACACTGCCGACGCCGGTGGCTGTGTCGACGGCAACGGCCAGCAACTGa
Protein Sequence: MTPQQVASSAASNVAATTTTTTAATTIPATANTTSNNNNNQNNNNNNNNNNNNSSSNNHNNNNNSSSEDPTTAAATIVDGWTSSTNLRYLHKKFKRLASTTEPESVDAMAAVRTTSLSSNSSLSPPLPVAAAPLLNGHVTVKHQQQTQPTPAATAAATTTTTTASAAPAATAATTIIQTPPATVAVAGLGEKTSRPKCPYCNLICAKPSVLEKHIRAHTNERPYPCNNCGIAFKTKSNLYKHCRSRSHLARMRGLDVPANETDGLSDQDGDGELSNSSSELLSVEVLSRTDSPYDEAMASPTPSPSTLSAAKSTYLQQPQLQQHMLQQLPLGSPAAGTLPPAPPADWLHSATAQHRQSLDYKPYKPKFHNASLYAPGTLKEATAATAAAAATAATAAAAQQQQQQQQQQQQPSLAHPTISPSTQLKLNNHINSHQLQLQLQHQHQQQQQQQHLHAQQSLLLAAAATNPVALSALPPPPPGVYYLGQPQYYNPTAAAMHQHALAIQQMQLQQHFQLQQQQQQQQQQHQNHQQQQQQQQQQQQQQHHQQQQQQQQHSPLLKAPQQQQQQQLLRSTSQQQAAVIATTAALPAPATPNPPTNLTSFASSSGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNNNNNSNNSSNITNSSSIPATAHANSNSNNNSNQQLGETKVNLAQAIVQKQQQQQHMQQQLQQQQQYQLYLQQQQQQQLEPPVNGLLKRSSSSSASSTASSGYASFKSTATSTQAAATTVNVKQLQQLPPPPSPLPLQQLQYRQDPSTPVPKLEQQQQQQLQLQQPLPLNLSAKPKPSLAMPAKPTPTATAAASATTTVVAKSTTTTAPAAAPNISIIKNLLLNARGLAVPIGEGDDAVYSCPICASKFRSADELKHHNSTYCQDANSSAPISPASSPSTKYFRSNSISFSLPELQSHMANSKNPLSLAKLAKVACSYQQQQQQQQQQHHINSSSSSINRNSSNNHIPATAATAVVIPPSIDATSVALRFVDAPLPSPGPLLGKTPLVDYAAPRKAPDAQVVITKMHEDRLENIIVEAPSKRLKLSSGETSFTLPSVVDMLFAGNPELQFTCKEERLRRFTSSGGTMIPISECPELDKSPKMIRTPLLSGGSFQEMSPRLSDIKERKLLAANNNNNNNNNNNNNNNNNNGFLLSASNTSHHFQFPPINSITAFNPLTLPPMCNSSSSNIVDKAIPYVPGIPGPGSLSLLPPPLQLQRGRSPNRKQPSPNTNANLNINLNPLLAAEGPLKALSPFGGVQNLPSEFSRQPPTPAQRNALQWTNSSSSSSSNKLPVIVADGTLAKKPPFNFLRMADNVKSSAVQEQQQQQQQQPQPLAMGMLEVRHFNFDNVNKSQEVLAPLHVDTPDEAAAAAVAAAIKTTTTTAILVAASTTATSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKMLGTGCTTAMAGAGKLQYSVFSSQETVSTCSTTANGQSKFYQHQLKQPPSIGALSEANVAAKASEEAAAKKLETGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSVSPYPPLVQDTPAASPANSIGSSAGSAAGSGSQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPNDESSAPMDLTKPRPMPSISVAASSPVADQMQAQTPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEIEEQAKRESEGEDVLLQTYIKEQALQHAKMKQSQFSRSYLVTSTSTTNSNCISSCSSNSTTTSVSISCVVTTPIVNSKPQLNIAELPSIEVHEVKTPESPTPSSALVKSAEESEESETQSDQEKPSIAATSIPVPVTVSVSVAVPVSSSKSSAEIQQPHNANLPAAVQQPDATDFSGVLSSSNSSSSNKNSNSSSGSSGSTAPTRIVVVGEDGFKTTPTSGSNELQSGGATTAATAAATAGATYTNRVVPPPPPPIASDARPTCTVCNKTFQRTHQLSLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLVEKDPNKLSGYTTPSGMLQLSADAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPKRASSMSEDETLTNGLGLSHSHSHGHSLKRRLQNSSFSSNGDESDNPTDTTGSGGSGSSEKRARSNTNEIITLPTPVAVSTATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00513682;
90% Identity: iTF_00499804;
80% Identity: -