Basic Information

Insect: Drosophila melanocephala
Gene Symbol: wdn
Assembly: GCA_037043625.1
Location: JBAMBD010000737.1:461877-465070[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00017 0.011 16.1 0.6 1 23 318 340 318 340 0.98

2 7 0.059 3.9 8.0 1.8 2 23 351 371 350 371 0.93

3 7 6.4e-07 4.2e-05 23.7 1.1 1 23 377 399 377 399 0.99

4 7 4e-06 0.00027 21.2 4.0 1 23 405 427 405 427 0.98

5 7 0.00021 0.014 15.8 3.0 1 23 433 455 433 455 0.97

6 7 4e-06 0.00026 21.2 0.8 1 23 461 483 461 483 0.96

7 7 9.5e-05 0.0063 16.8 2.3 1 23 489 512 489 512 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00017	0.011	16.1	0.6	1	23	318	340	318	340	0.98
2	7	0.059	3.9	8.0	1.8	2	23	351	371	350	371	0.93
3	7	6.4e-07	4.2e-05	23.7	1.1	1	23	377	399	377	399	0.99
4	7	4e-06	0.00027	21.2	4.0	1	23	405	427	405	427	0.98
5	7	0.00021	0.014	15.8	3.0	1	23	433	455	433	455	0.97
6	7	4e-06	0.00026	21.2	0.8	1	23	461	483	461	483	0.96
7	7	9.5e-05	0.0063	16.8	2.3	1	23	489	512	489	512	0.98

Sequence Information

Coding Sequence: ATGGAGTGTAAAGGCAAAGCAAAGAGAATGAAAGAAGAGGCGCCAAGCAAAAAATTGCCGCCTAAATTATATGGCGGCGATTATGCGGCCAATGCAAGCACCCCCACCAAAGCGGCCCACGATGAGATACTGAGCTCCTTGTTGCGCATCAACAATTTCGATTCCATATCGAGCATCAAAGACGAATCCCTCGACATCGATCTGTCCGCCTGCGTCACAATCAGCTCGGCCAGCTTCATCAATGGCAACAGCCTGTCGTCTACGGATTTTTGGCGCGTTCTCGACGAGAGTGCACAAAACAATACGGAATTAAATCTATCCTCAGATGTGTGCCGCGAGGAATTGAGTGcgcccagtcccagtcccacaCCCAGTGCGAATCTATCGAATGGCAGCGCCAATGACAATCATAATTCCGAGTTCAATGTTACGTTCCTGCGGCCAGAGCCGCCAAATGCGTTCACGAACTCACCATTTAAAAAgattacaacaacagcaacgacaacggcgGGGGCTGCGACAACGCCAGTGAAGCTCCAATCACCGGAGCAATTGCCAATGGTGCAGCAGATGGTTTCGCAACGTAAGCCACGTTTGCCCGCTGCGACAGCGGTACGGTTAAGGGTCTTCAAGGAGGAGCTCTTCGATGAGAAGGAGATGTCCTCCAAGGGAGCTGAGCTGTTGACCAAAGTGGAGCGTTCGGAGTCGGATCATATGCCGCCATCGTTTACCATATtccagcaaccacagcagcaacaacaacaacagcagcagcagccgccagtGAATAATATGCCGCCACCGGCTGTGCCGTTGGATTTCAATGGTAAACTAGAGTTGGAAACGCCGCCGCCACCTCTCTACAAGTGCCTGGACTGCAACGGCCTGATTCTTGACAATCAGCAGCTGGTGAGTAGCCACAAGGCGGCAGCGCATCGATTGCGCATCACCTACAACTGCACCGAATGCCAGCGCGAGTTTGAGCTCTTGGCCGGGCTCAAGAAGCACCTGAAGACGCACCGCAGCGAGGGACGCAAGGATACGTGGAAAAAGTGCCCAGACTGTGGGAAGTGTTTAAAGTTGGGCAGCATGTGGATGCACCGGAAGATCCACAGCGATAATAAGAAATATCAGTGCGATATCTGTGGTCAGAAGTTTGtgcagaaaatcaatttgacgCATCACGCACGCATCCACTCTTCGGAGAAGCCGTACGAGTGCCCCGAATGCCAGAAACGATTCCAGGAACGCTCCCATCTGCAGCGCCATCAAAAGTATCATGCACAGACGCGCTCATATCGCTGTGAGAAATGTggcaaaatgtataaaacgGAACGTTGCCTCAAGGTACACAATTTGGTGCATCTGGAGCAGCGTCCCTTCGCGTGCAATGTGTGCGACAAGAGTTTCATTAGCAACTCAAAGTTGAAGCAGCATTCGAATATTCATACGGGCATGCGACCGTTTAAATGCAACTATTGTCCGCGCGACTTTACCAACTTTCCCAATTGGCTGAAGCATACGCGACGCCGTCACAAGGTCGATCACAAGACTGGCGAGCATCTCGAGAACATTCCCTCCTACTGCTCCAAGAAATCAACGACAACGAAGGCACAGAaggcagctgccgccgctgctgctgctgctgcggcggcggcggcggcaacggcgacaacaGCCGGATCTCCAGCATCAGAATTGCTGCCTCTCAGCACAGCTGATGGAGAGGCCAAGTCCACATCCTCCTCAACGCCGCAGACAGGCAAAGGGCCGTCAGCTGCAGCGCCAGCTCCACCAGTTAAGCAGGCACGCAAAAagaagcaaccacaacaagcaACTCTTGCCGCTTTGGGCATCACTTTGCCAGCGGGAACGGCACTGCAGCAGGTGCATCCGCCGCAGCCGCTACCACAGTCCACAAGCAAACAGTCAAATGTTGCTCCGCTACTGGCACAACCatcacaagcagcagcagcaatagcaaccaCCGCTCCAGCCAAGCAGATAAAAGCGAAACGAGAACGCAAACAGTTGGCGCccaaacagctgcaacagaaGCCATCTGCGCCAGTGGGCAGCAATCCTCACACGGTGCCCGTCGCAATGCcgcaaattaaaaaggaacCGTTGCCGACGCAGGGTCCATTCCTGGACCTGCATGGCCTTAGCCTCACATCGGCCGAGGAGCTGATCATGGAGCAGGCCCTCGAGATGGAGGAGTGCGGATTGTATGATACACCCGTGGGCAACACTGAAATGGGCACCTCAGACAATGCAACCGCCTCGGATGCAGCGACTGCCCTGCactttcaaatcaaaaacgaATTACCCGATGAACTTCTACCTGACGACGATTTCTtgCCCCACAAACCCAATAGTGGCAATCGCATAGCCTGTCCATCGCTGGAATCATCACCATTCTCCTCGCCCGCATCCATGGAACTGGCTGCGGtatccaccaccaccaccaccagcagtaGCACCATCAAATCCACATCAGCTGTGAATGTGAACACGGGTCGCACCGCCAACTATTATTTGCCAGCATTTACGCTGAATGCCCAAGGCAAGTTGACCAGTTGCACGACCAGCACTGGCACTTGCATGGGAACGGGAACAGGAGCGACCAATGCTATTGCCAGTGGACCGACAACAGTGTCTGTTGTGAATATGCCAATGTTGGTACACTCGAATCAGATGTTGCCATCCGTGGACACTCTGCTCTTTACCACCCAGACGGGCAATCGATTCTTCTCGGGCAAGGCAGCCTCAGGTGGCGCCTCAGTCTCAACGACGACCCATTTGACATGA
Protein Sequence: MECKGKAKRMKEEAPSKKLPPKLYGGDYAANASTPTKAAHDEILSSLLRINNFDSISSIKDESLDIDLSACVTISSASFINGNSLSSTDFWRVLDESAQNNTELNLSSDVCREELSAPSPSPTPSANLSNGSANDNHNSEFNVTFLRPEPPNAFTNSPFKKITTTATTTAGAATTPVKLQSPEQLPMVQQMVSQRKPRLPAATAVRLRVFKEELFDEKEMSSKGAELLTKVERSESDHMPPSFTIFQQPQQQQQQQQQQPPVNNMPPPAVPLDFNGKLELETPPPPLYKCLDCNGLILDNQQLVSSHKAAAHRLRITYNCTECQREFELLAGLKKHLKTHRSEGRKDTWKKCPDCGKCLKLGSMWMHRKIHSDNKKYQCDICGQKFVQKINLTHHARIHSSEKPYECPECQKRFQERSHLQRHQKYHAQTRSYRCEKCGKMYKTERCLKVHNLVHLEQRPFACNVCDKSFISNSKLKQHSNIHTGMRPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLENIPSYCSKKSTTTKAQKAAAAAAAAAAAAAAATATTAGSPASELLPLSTADGEAKSTSSSTPQTGKGPSAAAPAPPVKQARKKKQPQQATLAALGITLPAGTALQQVHPPQPLPQSTSKQSNVAPLLAQPSQAAAAIATTAPAKQIKAKRERKQLAPKQLQQKPSAPVGSNPHTVPVAMPQIKKEPLPTQGPFLDLHGLSLTSAEELIMEQALEMEECGLYDTPVGNTEMGTSDNATASDAATALHFQIKNELPDELLPDDDFLPHKPNSGNRIACPSLESSPFSSPASMELAAVSTTTTTSSSTIKSTSAVNVNTGRTANYYLPAFTLNAQGKLTSCTTSTGTCMGTGTGATNAIASGPTTVSVVNMPMLVHSNQMLPSVDTLLFTTQTGNRFFSGKAASGGASVSTTTHLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01323591;
90% Identity: iTF_00514391;
80% Identity: -