Basic Information

Insect: Drosophila melanocephala
Gene Symbol: hang
Assembly: GCA_037043625.1
Location: JBAMBD010000015.1:789590-801386[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.25 16 6.1 1.0 3 23 495 516 494 516 0.93

2 15 0.32 21 5.8 3.2 3 22 608 627 606 627 0.89

3 15 0.00053 0.035 14.5 3.3 1 22 743 764 743 766 0.90

4 15 0.062 4.1 8.0 0.1 2 21 778 797 777 798 0.93

5 15 0.00062 0.041 14.3 0.2 2 23 923 945 922 945 0.95

6 15 0.0018 0.12 12.8 0.1 1 23 953 976 953 976 0.96

7 15 0.00014 0.009 16.4 0.2 2 23 1067 1088 1066 1088 0.97

8 15 0.00026 0.017 15.5 2.9 2 23 1188 1210 1187 1210 0.97

9 15 0.02 1.3 9.5 0.2 2 23 1219 1241 1218 1241 0.95

10 15 0.0012 0.079 13.4 0.3 1 23 1254 1277 1254 1277 0.97

11 15 0.00011 0.0074 16.6 1.1 1 23 1336 1358 1336 1358 0.99

12 15 0.0017 0.11 12.9 0.9 1 23 1366 1389 1366 1389 0.96

13 15 0.061 4 8.0 0.4 2 19 1397 1414 1397 1415 0.94

14 15 0.0014 0.091 13.2 0.3 3 23 1526 1546 1525 1546 0.98

15 15 0.00094 0.062 13.7 0.1 1 23 1581 1603 1581 1603 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.25	16	6.1	1.0	3	23	495	516	494	516	0.93
2	15	0.32	21	5.8	3.2	3	22	608	627	606	627	0.89
3	15	0.00053	0.035	14.5	3.3	1	22	743	764	743	766	0.90
4	15	0.062	4.1	8.0	0.1	2	21	778	797	777	798	0.93
5	15	0.00062	0.041	14.3	0.2	2	23	923	945	922	945	0.95
6	15	0.0018	0.12	12.8	0.1	1	23	953	976	953	976	0.96
7	15	0.00014	0.009	16.4	0.2	2	23	1067	1088	1066	1088	0.97
8	15	0.00026	0.017	15.5	2.9	2	23	1188	1210	1187	1210	0.97
9	15	0.02	1.3	9.5	0.2	2	23	1219	1241	1218	1241	0.95
10	15	0.0012	0.079	13.4	0.3	1	23	1254	1277	1254	1277	0.97
11	15	0.00011	0.0074	16.6	1.1	1	23	1336	1358	1336	1358	0.99
12	15	0.0017	0.11	12.9	0.9	1	23	1366	1389	1366	1389	0.96
13	15	0.061	4	8.0	0.4	2	19	1397	1414	1397	1415	0.94
14	15	0.0014	0.091	13.2	0.3	3	23	1526	1546	1525	1546	0.98
15	15	0.00094	0.062	13.7	0.1	1	23	1581	1603	1581	1603	0.97

Sequence Information

Coding Sequence: atgtcgacgacgacgacgacgactctTTGGCCTGCGCCCCCGGCAACGACATCATCATCtacgtcggcgtcgtcgttgtcgtcgtcgtcttcgttgTCGTCGGCACGTTGTTGCTGCGTGTACTTTGGTTGGTGCCTGGTGTGCTTGCTGGGCTGCTCTTTGGTTTCGCTTTGGCTCGATTTCATGATCACATCGGTGGATCGTCTGTCGTTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCACAGTCGAAGCAGCGCCAATGGCTGGAGACGGACAAAACCAAGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGGGCCGAGAATGGCAACACCATtgaccaacaacagcagcagcagcagcaacagcagcagcagcagcacgaatTGAAAATGGATTCAGCGACGGCTGCAGCTGAAAAGGCGTCCGCTGCCAACATTTTGGATGGCATACCTCAGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCGAGTcccaagcaacagcagcaagcacagcaacaacagtcgcaGCAACATTCTCAGCAACAGCATGCAACAGGGGCAAGATCAACAACGAAAACatcagcggcggcggcggcggtgccAGAGTCgcaacaaatattgcaaacCCTTTTATTGCAGGTgcccacagcaacagcagcagcagcagcagcagcgacattgGCAACGTCgtcaacacagcaacaacaacagcagcagcagcgcaagtatcaacagcagcagcagcaacgtggcaagcagcagcaacatcagtatcatcaacagcagcagcgacagagTCGCGTTCGTCAACcgcgacgacagcagcaagcCGCAACGGGCAAATTCAGGAGCAAGTTGTATGTGCCATTGGACATATCGGTGCCAGCACTACCAGCGCTgttgccgccaccgccgccagctgttgctgatgcagcgtcgttgccattgccgctgtcgctgccacTTGATTTCAGCCAGAATCCGAATCCAAATCCCAATCCAAATCTAAATCAGAGATATACAAGTAGCGTTTTAGTGTCGCAGCCGCCGTCGCTGCCCCCGCCAGTTGCAACAATGAGCAGCAACGAGGCTGCCATTGCCGCTGCCACTGGCTGtggtgcaactgcaactgcaaccgcaGTCACGACTCCATTACTCATGCCGCCGCTGCCTGCCGTGCCCATCAAGGATGAGCCCCTGGACGATACGGATGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCactaaatACCTCCGACTATGATTATACGGCTCAGCATGGCGTGACCGCTGTTGTGGCGGCTGCGTCGCTGCCGGCCAGCGCCGTTGCAAATGTGGCCGCCGCTGGCGACTCAAAGGTGGCCAGCTGCCGGGCGTGCAGTCTGCAGTTCTCGACGCGGGCGAATGCGCGACGCCACGAGCGCAATCTGCACCCGAATCTGTTTCAATTGTCGACAGACTCACCAAATAATACGCCAATCACCAAACCGACACCGGCCCTCGCCGCCGCCTTGGAGATACAGCgtgcagcggcggcggcagcgcaACCGCTGAGGCAACGCGTGGTGATGAACACGTTCATCAAATGCGAAAACGGCGGCTTCGACTACGACAATCCCGAACAGTATCAGCAGCTGTTGTCGCACGACAAAGTCGACTTCATACAGGAGAACAGCGAGTTTCTCGAACAGTACCAGACGATGACGTGTCGCTGTTGCAACAAGTACTTCAGCACATACAAAAACTTTATGGCGCACGTACGCAAAAAGTATCCGTTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCACTGCGCACCAAACAGCCAAACTTTGTccatgccaatgccaatgcctcATCCACTTCCACTCCAGCCGCAACGACTGCTgtacaccaacagcagcagcagcagcagcagcagcagcagcaacagttggtgACAGCAAACgaaacagcaccaacaacaacagcaacaacatcaacggaTCGTCCGGAGAAGTTGCGTGCCAAGGAGCTGCTGGTCAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGTTTTCGCACAAAGCACGAGTTCCGCACCCATGTCTACGACAAGCATGCGGATGTCCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCTGTGGATCGTCGAAGGCACTACAATAACATGGATTGCATTGTCCGGCTGCGCTGCATGACCTGCGATGCGAAACTGGAGACGCATCAGCGATTCCTCGACCATGTCTATCAGGATCATTTGGGCGGGGTGAGCAGTGATAATGCATCGTCTACGGCGACGACCAGCGGCATGGATCATTCGCCCGGGAAACGCAGTTTGCTGGGCGCCCTTGGCATCGGCGTTGTCAGCCAATCGTCCAATGATGAGtcgcgcagcacaggagcagcaacagttgttggaggaggaggaggaggaggaggaggagcagcagcagcagcagcagcagcaaccagtgGCGGATCGACAACATCGGGCAGTCGAGATGCACCCAAATCACAGTATTTCTCACGAATGCCACAGGTCTGTCCGATCTGCGGCCAGCAGtacaacaactataacaatGTGTTGCGCCACATGGAATCGAAGCATCCCAACAAATTGCCCGAGACATACAAGTGTGTCCGTTGTGGATTGGGATATCCGCGGATCTCCTATCTGCGGGAGCACATGATCAATGTGCATGGCGTTGACAAGAATCGGCATTCGGGCGGCTTTGAATATATTGTGAATGCCGATGCGGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACGGGACGATATGATTATGTGATGAAGGATCTGATGTCTATAACAAATGGTGGGACACTCgatgatgatgacgatgatggcgGCACCGGCGGCAACATTGCCAAAAAGATGAGACTCGAtgatagcagcaacaacagcagcagcatcaacatgAGCAGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTTAGCAACAATATTGGTCTGTCGAATCATATGCGTTCCCATTACACAGCATCGATAACGACAAGTGCTGCTCTGGCGGCTGCCAATCGCATGACGCCCAAATCGCTGACAATAACAGCGACGCCACCGCTGGAGacaacgacagcaacaacaactgcagctggagttgcagcagtggcagcatcatcatcaggaGCAGTCgcctcaacagcaacagcgtcaGGATCAGGCTCATCATCCGGCAACTTGCCGCCAGCAATGGTGCACCAGACGGCACAGGAGCAGGCGGTATTCCGTCGCAGTCTGGATCAGGCGGCCGATCGACGATTCCGTCGAATGCGCTGTCGCATCTGTCAGCGCAGATTCAGTTCGAAGAAATCGTATCGCTACCACATGCTCACCGACCACCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCGGAGTTCGCCTACGAGAAGGGGCTCAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAGGACGAGATGATTATCAAGCAGTTCGAGTGCGATGTCTGCTCCACGGTCTACAGTTCCGAGCTGGaattgcagcagcacaagcgCAGCGTACACAAGTCACAAGCCACTGATTCATCGTCATCAGcagttggtggtgctggtgctgctgctggcaaatcATCATTGAAATCTGCCACTGCTACTACCTCATCGACAGCTGAGCTGGTCGCAGACACATCATCCTCGTCGGGCACGGCGGGTCCGGCAATTCTGCTGCCACTCTACTGGTACCAGTGCAAATATTGTCCATCCAATTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGTGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGGTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTCTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAGcaggatcagcagcagcagcagcaacaacaacagcagcagcagcagcagcaacaacagcttcaGCTGCAACATCATCAGCGACTCATCTTCAAGCACAAAAcgggcgatgatgatgacgaggaggaggacgatGATCCGTTGCTGCTAATGGACGATGGCGGTGGCGGCAGCAATGATAGCAATGCTGGCAATGCCattgcatcagcagcagcagcagcagcagcggcagcagcagcagtcacaatAAATACGAGCACAATGAAGATACGCATTCCGGAGGTTGCATGCACCATTTGCGGTGCCCGTTTCACCGATCAGGAAATATTCACCAAGCACATACAGAAACACGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCGATGTTCGATGATGGGCCAGCGGATGCCGGACAGTTTCAGGTTGAGCACCAGAACGAGAATGGGGAATACGCGTGCGATTTGTGCACCAAGACGTTCCCGCAGGTGATAGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGATCCCAATCAACGACGGCGAAGCGACAACGctgaacaacagcagcaacaacagcagcagcagcaacaacaacaacaacttcgcTGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCGGTGGGCCTGATGcccaatcagcagcaacaccaaaagcaacaacagcaacaacaacagcagcagcaacagcagcagcagcagcagcagcaacaacggaCGAGCAAATCAATGAAACGGAAACGTGA
Protein Sequence: MSTTTTTTLWPAPPATTSSSTSASSLSSSSSLSSARCCCVYFGWCLVCLLGCSLVSLWLDFMITSVDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLETDKTKQQTLLGYLDLNRAENGNTIDQQQQQQQQQQQQQHELKMDSATAAAEKASAANILDGIPQLKKRKSLTVYVSPSPKQQQQAQQQQSQQHSQQQHATGARSTTKTSAAAAAVPESQQILQTLLLQVPTATAAAAAAATLATSSTQQQQQQQQRKYQQQQQQRGKQQQHQYHQQQQRQSRVRQPRRQQQAATGKFRSKLYVPLDISVPALPALLPPPPPAVADAASLPLPLSLPLDFSQNPNPNPNPNLNQRYTSSVLVSQPPSLPPPVATMSSNEAAIAAATGCGATATATAVTTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAQPLRQRVVMNTFIKCENGGFDYDNPEQYQQLLSHDKVDFIQENSEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPNFVHANANASSTSTPAATTAVHQQQQQQQQQQQQQLVTANETAPTTTATTSTDRPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASSTATTSGMDHSPGKRSLLGALGIGVVSQSSNDESRSTGAATVVGGGGGGGGGAAAAAAAATSGGSTTSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDDDGGTGGNIAKKMRLDDSSNNSSSINMSSIANQQKECLICNAVFSNNIGLSNHMRSHYTASITTSAALAAANRMTPKSLTITATPPLETTTATTTAAGVAAVAASSSGAVASTATASGSGSSSGNLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELQQHKRSVHKSQATDSSSSAVGGAGAAAGKSSLKSATATTSSTAELVADTSSSSGTAGPAILLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQQQQQQQQQQLQLQHHQRLIFKHKTGDDDDEEEDDDPLLLMDDGGGGSNDSNAGNAIASAAAAAAAAAAAVTINTSTMKIRIPEVACTICGARFTDQEIFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVEHQNENGEYACDLCTKTFPQVIALKVHRKWHFRGDSKQIPINDGEATTLNNSSNNSSSSNNNNNFAELIIDAASTRTACGGPDAQSAATPKATTATTTAAATAAAAAAATTDEQINETET

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -