Basic Information

Insect: Drosophila melanocephala
Gene Symbol: Prdm15
Assembly: GCA_037043625.1
Location: JBAMBD010000012.1:43318-47848[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.00049 0.033 14.6 0.9 1 23 213 235 213 235 0.97

2 24 0.00058 0.038 14.4 2.8 2 23 242 263 241 263 0.97

3 24 0.019 1.2 9.6 0.7 2 23 296 317 295 317 0.96

4 24 0.00023 0.015 15.6 2.0 1 23 392 415 392 415 0.94

5 24 0.19 13 6.5 0.6 2 22 425 445 425 445 0.96

6 24 4 2.6e+02 2.3 0.4 1 19 454 472 454 474 0.91

7 24 0.9 59 4.3 2.1 1 23 592 615 592 615 0.95

8 24 0.016 1 9.8 0.7 1 22 624 645 624 660 0.94

9 24 6.1e-05 0.004 17.4 0.4 2 23 674 695 673 695 0.97

10 24 1.4e-05 0.00089 19.5 5.2 1 23 701 723 701 723 0.98

11 24 0.11 7.3 7.2 1.0 1 23 862 885 862 885 0.95

12 24 0.0019 0.12 12.8 1.9 1 22 892 913 892 913 0.96

13 24 0.38 25 5.5 0.4 1 20 922 941 922 945 0.86

14 24 5.6e-05 0.0037 17.6 1.6 1 23 969 991 969 991 0.97

15 24 0.00042 0.028 14.8 0.7 1 23 998 1020 998 1020 0.98

16 24 0.07 4.6 7.8 0.0 2 21 1047 1066 1046 1067 0.94

17 24 0.037 2.4 8.7 4.0 1 23 1112 1135 1112 1135 0.96

18 24 0.0063 0.42 11.1 1.5 1 23 1172 1195 1172 1195 0.96

19 24 0.013 0.88 10.1 3.1 1 23 1222 1245 1222 1245 0.97

20 24 1.3e-05 0.00084 19.6 0.1 2 23 1266 1287 1265 1287 0.95

21 24 4.3e-05 0.0029 17.9 2.9 1 23 1293 1315 1293 1315 0.99

22 24 3.9e-06 0.00026 21.2 2.3 1 23 1321 1343 1321 1343 0.97

23 24 2.7e-07 1.8e-05 24.9 2.6 1 23 1349 1371 1349 1371 0.99

24 24 0.0011 0.074 13.5 0.3 1 20 1377 1396 1377 1401 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.00049	0.033	14.6	0.9	1	23	213	235	213	235	0.97
2	24	0.00058	0.038	14.4	2.8	2	23	242	263	241	263	0.97
3	24	0.019	1.2	9.6	0.7	2	23	296	317	295	317	0.96
4	24	0.00023	0.015	15.6	2.0	1	23	392	415	392	415	0.94
5	24	0.19	13	6.5	0.6	2	22	425	445	425	445	0.96
6	24	4	2.6e+02	2.3	0.4	1	19	454	472	454	474	0.91
7	24	0.9	59	4.3	2.1	1	23	592	615	592	615	0.95
8	24	0.016	1	9.8	0.7	1	22	624	645	624	660	0.94
9	24	6.1e-05	0.004	17.4	0.4	2	23	674	695	673	695	0.97
10	24	1.4e-05	0.00089	19.5	5.2	1	23	701	723	701	723	0.98
11	24	0.11	7.3	7.2	1.0	1	23	862	885	862	885	0.95
12	24	0.0019	0.12	12.8	1.9	1	22	892	913	892	913	0.96
13	24	0.38	25	5.5	0.4	1	20	922	941	922	945	0.86
14	24	5.6e-05	0.0037	17.6	1.6	1	23	969	991	969	991	0.97
15	24	0.00042	0.028	14.8	0.7	1	23	998	1020	998	1020	0.98
16	24	0.07	4.6	7.8	0.0	2	21	1047	1066	1046	1067	0.94
17	24	0.037	2.4	8.7	4.0	1	23	1112	1135	1112	1135	0.96
18	24	0.0063	0.42	11.1	1.5	1	23	1172	1195	1172	1195	0.96
19	24	0.013	0.88	10.1	3.1	1	23	1222	1245	1222	1245	0.97
20	24	1.3e-05	0.00084	19.6	0.1	2	23	1266	1287	1265	1287	0.95
21	24	4.3e-05	0.0029	17.9	2.9	1	23	1293	1315	1293	1315	0.99
22	24	3.9e-06	0.00026	21.2	2.3	1	23	1321	1343	1321	1343	0.97
23	24	2.7e-07	1.8e-05	24.9	2.6	1	23	1349	1371	1349	1371	0.99
24	24	0.0011	0.074	13.5	0.3	1	20	1377	1396	1377	1401	0.93

Sequence Information

Coding Sequence: ATGTTGCCGACGAATATTTGCCGCACGTGTGCGTTGCAAGATGACAACTTGTTGGCGTTGGCAACGCGGAGTGAGAAATACGCAAAGAAAAGTATTTGCGACATGCTGCACGAATTAACACAAAACGATCCACTGCTGGAGCATACAGATGATAAGCTACCACAGCATTTGTGCGGCCAATGCTTGAGCCAGCTGGAAGCTGCCTATGCATTTGTGCTGCAGGCACGCCAGACGCAggagcaactgttgctgcagctacGTAAAGGATTGCAGACACAGTGCCTGGACGAAACACCCATCGATATAAGCATAGAGCACATCAAAATCGAAACAGACATTGACCTAGATGCAGACATGGCTGACTTAGTCGATGCTGAGTTGGAGGAGGAACAGGAGAAGCAGGTGGCCTTAAAATGTCAGCCGGCAACTGATAGCGATAGCAGTCAAGATAATGTGAAGGACCATCACATTAGGGTCAAAACTCCGCAGCTGCGGCGCAGTGCACGGCGAGCCAAATTGAGCACAGACAGCGAAAATGAGTCCTCCGAGCAGGTGAAGCCGTTACCTGTTAAGCGTGGACGCGGTCGTCCCGCACGTCTGGCCAAGAGGGAGACGACCACCAACAAGGACGGACGGCATGTGTGCGAGGTGTGCGGCAAGACCTTCTCCTGGTATCGTGACATGCAGCGCCATGCGCGCATCCACTTTGAGCAGGCGGGTATTGTGTGCGAGCACTGCGGCAAGAAGTTCCTGCGCAAGGACAAGTACATGACACATCTGCGATCGCACAAGAAGCACACAaccacagacagacagacactgCCACGGAGCAGCGAGTGGCGCTACGCGGAGCGTCTCTACAGCCCCGGCAGATTCATGCGTGTGGAGTGCAAACTGTGCGGCTTGAGTTGCCAGCGCATTCGGGAGTTGCGCGAGCACCTGGCGAGTCATGTTCACATTGAGACATTGTCGAATCTCAGCCTGGATAACGATGTCATCCGAGAGCAGTTTGGCAGCCAATTGGATTTGCAGCAAATCAAGGAAAAGGTGTGCACGCAAATTGCCAAAGGTCGCGAGCAACTGGAGAATTACGGCGCCGTGGTGAATGCTTACGGCTATGAGCTGTGCCTCAGCGACtcggatgaggaggaggatggGGAGCTGGCTGGCAAATATCAATGTCTGCGCTGCAATGTCAGCTTTGCACGCAAGCATCAACTCATGCGTCACACGCTCGAGGAGCACACGGACAGAAGTGAGACTCTTTTGGAACGCTGCAATATCTGTCAAATTGGCTTTGTTTGCGCCAAGCTGCTGGAACAGCATCAGCGCACGCAGTGCCTAAATCCGCTGAAGCGTTACAGCTGCGAGAATTGTCCTGGCAAGTTTATTTGGCTGCAGAATCTGCAGCAACATGCATGCTGCAGACTGCAACCGGATATGCAGCATCGGCAtccagagcagcagcaggcaactcATCACCAGATACAATGTTGCCTGTGCGAAGTCCAACCCAGCAGCATGACTGCCCTACGCTCTCATTTACTCACGCATCGTGATGGACATACCGACATTGATCCGCAGCAGCAATCTGCCTTCTTTCGCACCTATTACGAGGATGACGGCGCCAGCAGTCTGTCAGAGCTCAGCGCACGCATCGCTGGCGATTTTGAGGCACAGCTTTATGGAAGATATTTCAATGCGTGCACGGACAGTGGACAAGAACTCGACTTCAACGATTCCGACAAGGAATGGAGGGATGCGCCCGCTCTGCACAGCTGTGCCGTGTGTGGCGAGAGCAGAAGCTGCCTCGATCAGCTGCTCCAGCATCAGCAGAGCCAGCACATAGAGCTAGCGGGCAGCCTGCCTCATGTCTGCTCCGATTGTGGATTGGGCTATGTGGCCgagtcgctgctgcagcagcatcTCAAGCGCTTCTATTGGCACTCCAACTACGAGCGGCACATTCAGGTGCAACATCCTACGGATAcgaagcaggagcaggagaagAGCAAGCTGCAGTGCAGCGAGTGCGATAAGGTGTTCATCTGGCCCAAGGATTTGACGCGCCACAAGCGCATGCATCAGTCGCAGGTGCAGTTCGAATGTGCGCACTGCGATCGCAAGTTTCATCGCAAGGATGGTCTTAAGTCGCACATGCGGATGCACGGTGAGCAGCCGACGTCGTCTCTCGGTGAGCAGCTGCAATGCATGCCGATGGTTTTGAGCCAGCTATGTCGCCCCAATGGCTGCAAGCAGATCAAATGCATGATTTGCCTGTCGCAGCACACAAAGATCTCCGATTTGCGAACGCATTTGACTAGCCATCAGTTGACGCTGTGTTTGGCCGAGGAGCGAGGCATCACAAATATTTGTCGTGCTCTTTATCCGGAGCTGAACACGCCACTGGATCAGCAGGCATTGATCAAGCGCATCCAGCGTGATCTAACCAATGGCTTGGAGCTGGAAAGATTCGTTTCGATAACCAACGAGGCGGGCATCGAACTAAGCCTGGACAGCAGCGAAACGGACACGGATTCAGATTGTGCAGCAGAAACCGAACGGAGCAGCACGGAACGCCGTTACAGCTGTGAACTGTGCCAGGTGCAGGTGATGCGCAAGCATCAGCTCTATGCGCACCAGCTGGAACAGCACACGTGGCACCAGACGACGCACGTGTGCAGCCACTGCCAGGCGAGTTTCGTGAatgagcagctgctggagcATCACTATCGCACCCTCTGCCGCAATGCACATCGGCGTTTCCTGTGTCGCAAGTGTCCGTTGCGCTTTCGCTGGCGCGATAATTTGAAGCTGCACAATGGTGTGGCGCATCAGGAGCGAGGGACTGTGGAACAGCACGCCAATATGGACATTCAGTTGCGTATGCTGCCCGTGGTTAGCTACGACTGTGTCGAGTGCAAGCGTAgcttcaaaatgcaaaaggaTCTCACACGGCACACCCTGATGCATGCCCAGGAGTCGAGCATCTACCGGTGTCGCTGGTGCGCACGACGCTTCTATCGCGAGGCGAATCTGCTGCAGCACATCGAGCGACATGGCATCAGCGCCGACCAGCTGCCCTATGCGGAGGCCCTGCTCAACGCAAGCCGGCATCCGCATGGCCCGAAGTGCATCCAGTGTCGCGTTTGTGAATTATCCTTTGCTAGCATTGCTGCACTGCGTTTGCATCTGCAATCGTCGTCAGTTGGCACTCATCATCCGATTGAGTCTATGGCCAACTATTCGATCACCAATCAGCTGGGCTACGAGCTGCACCTGGACGACTCTGAAACGGATGAGGAAGCCAAGCCGGCCGGCACTCCAGCGCATTACACGTGCGGAATGTGCCAGCTGCGCTGTGTGCGCAAGTTTGaactgcatcagcatcagcaggcCATGCATCGTCTGGAGCGCATCGCCGACGGCTGCAATCTGTGCATCTTCAAGAGCGTCTCGCCCGATCTGATTGCCTATCATCGGCGTGTGCTGTGCGAGAACACGGAGAAGCAGTTTAAGTGCTCTAAATGCAGCTACAAGTTTATGTGGCAGTCGAATTTGGTGCAGCACATCCAACTGCAGCATCCCAGCAGCGAGGAGtcgccaacaaaaacaacaatgcccAAGACCGTGCCCGACATTGACAACGTCGAATGTCACATCTTCCAGTGTGGTCAGTGTCCCAGTAAATACAATCGCAAGGATCGCCTCACGGCCCATGTGAAAAAGTGTCACACAACTGGCGCAACTGCGTCAACAAAATCGCCAGCGGCTACCAAGCAGCAGAAGAGTTTCCTGTGCGCCTTTTGCGGCAAGGCGGTGAGCTCATCCTCCAATTTAATCATACACATACGTCGGCACACCGGCGAGAAGCCGTTCAAGTGTGATTACTGCGACATGGCCTTTCCGCGCTCCTCCGATCTCCAGTGCCATCGACGCACCCACACCGGCGAACGGCCCCACATCTGCACCGTCTGTAAGAAGGGATTCGCTCGCTCATacaagctgcagcagcacatgCGCATCCACAACGGCGAACGGCCCTACAAGTGCACCTTCTGCGACAAGAGCTTCACCCAGTCCAATGACCTCACCCTCCACATCCGCCGCCACACGGGCGAACGACCTTATCAGTGCAATACTTGCGGCGAGCGATTCATTCAGGGCACAGCGCTCAAGAACCATCGAGTGCAGAATGGCCACTACGAGACGGAAGTGGATCAATCGAAGGATGACTAA
Protein Sequence: MLPTNICRTCALQDDNLLALATRSEKYAKKSICDMLHELTQNDPLLEHTDDKLPQHLCGQCLSQLEAAYAFVLQARQTQEQLLLQLRKGLQTQCLDETPIDISIEHIKIETDIDLDADMADLVDAELEEEQEKQVALKCQPATDSDSSQDNVKDHHIRVKTPQLRRSARRAKLSTDSENESSEQVKPLPVKRGRGRPARLAKRETTTNKDGRHVCEVCGKTFSWYRDMQRHARIHFEQAGIVCEHCGKKFLRKDKYMTHLRSHKKHTTTDRQTLPRSSEWRYAERLYSPGRFMRVECKLCGLSCQRIRELREHLASHVHIETLSNLSLDNDVIREQFGSQLDLQQIKEKVCTQIAKGREQLENYGAVVNAYGYELCLSDSDEEEDGELAGKYQCLRCNVSFARKHQLMRHTLEEHTDRSETLLERCNICQIGFVCAKLLEQHQRTQCLNPLKRYSCENCPGKFIWLQNLQQHACCRLQPDMQHRHPEQQQATHHQIQCCLCEVQPSSMTALRSHLLTHRDGHTDIDPQQQSAFFRTYYEDDGASSLSELSARIAGDFEAQLYGRYFNACTDSGQELDFNDSDKEWRDAPALHSCAVCGESRSCLDQLLQHQQSQHIELAGSLPHVCSDCGLGYVAESLLQQHLKRFYWHSNYERHIQVQHPTDTKQEQEKSKLQCSECDKVFIWPKDLTRHKRMHQSQVQFECAHCDRKFHRKDGLKSHMRMHGEQPTSSLGEQLQCMPMVLSQLCRPNGCKQIKCMICLSQHTKISDLRTHLTSHQLTLCLAEERGITNICRALYPELNTPLDQQALIKRIQRDLTNGLELERFVSITNEAGIELSLDSSETDTDSDCAAETERSSTERRYSCELCQVQVMRKHQLYAHQLEQHTWHQTTHVCSHCQASFVNEQLLEHHYRTLCRNAHRRFLCRKCPLRFRWRDNLKLHNGVAHQERGTVEQHANMDIQLRMLPVVSYDCVECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYREANLLQHIERHGISADQLPYAEALLNASRHPHGPKCIQCRVCELSFASIAALRLHLQSSSVGTHHPIESMANYSITNQLGYELHLDDSETDEEAKPAGTPAHYTCGMCQLRCVRKFELHQHQQAMHRLERIADGCNLCIFKSVSPDLIAYHRRVLCENTEKQFKCSKCSYKFMWQSNLVQHIQLQHPSSEESPTKTTMPKTVPDIDNVECHIFQCGQCPSKYNRKDRLTAHVKKCHTTGATASTKSPAATKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCKKGFARSYKLQQHMRIHNGERPYKCTFCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRVQNGHYETEVDQSKDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577186;
90% Identity: iTF_00610043;
80% Identity: -