Dmea001281.1
Basic Information
- Insect
- Drosophila melanica
- Gene Symbol
- -
- Assembly
- GCA_004143765.1
- Location
- SCDT01005267.1:781-5040[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.039 4 8.3 0.4 1 23 803 826 803 826 0.96 2 11 4 4e+02 2.0 0.2 1 23 990 1012 990 1012 0.91 3 11 8.9e-05 0.0089 16.6 2.7 2 23 1015 1036 1015 1036 0.97 4 11 3.4e-05 0.0034 17.9 0.2 3 23 1044 1064 1042 1064 0.98 5 11 2.8e-07 2.8e-05 24.5 4.1 2 23 1071 1092 1070 1092 0.97 6 11 2.5 2.5e+02 2.6 0.4 5 23 1105 1123 1102 1123 0.95 7 11 0.67 67 4.4 5.4 3 23 1130 1151 1128 1151 0.93 8 11 0.071 7.1 7.5 0.2 2 23 1162 1182 1161 1182 0.96 9 11 2.7e-05 0.0027 18.2 0.4 1 19 1188 1206 1188 1210 0.95 10 11 7.8e-06 0.00078 19.9 0.5 1 23 1218 1240 1218 1240 0.98 11 11 3.6 3.6e+02 2.1 4.2 1 12 1246 1257 1246 1257 0.91
Sequence Information
- Coding Sequence
- tgGGCAAACAGCGAGGATGAGAATCACGGAAAGCTGGCACACGATCATGTCGAGGATGGCGACGATGAGCACGAGGATAGTCGCAGCAGAGTTGGGCCCAAGACCACATCGAAAAAGTCACGCAAGTCGAaaccaaatggcaaaaagcaCAAACGGGTTGCCAAACATCAGCCGGATGATGAGGACGACTTTATGAGCATAGGCAGCAGCTGTGCTGAGAGCGATCATCAGCTGGAGGAGCAACAGCCGACGCAGGCGCATGCAGCACCGGCTGCGTCCGCGTCGCCATCTCAACTATGCACTGCGCCTTCGACAAGcagtggagcagctgctgcagctgcggctgctggcgGATCAAGCGGTGCCAGCTCGACAACTAGCGGCTCCATCAAGTCCAAGAAAAATCGTGTGACGGTGCTCAGCGATGTGCCGCTGAATATGAACGAGTATCTGGATCTGGTGGGCAACATTGTGGCTTCCAGTCGTATTGGTGCGGCTCGTCCGTTTGCCGCCGTGGCGCCTATACCGTTAGTCAAGGTGGAAAAGGAGGAGCCGCTGGACGACTACGACTCTATGCGGAATGCAGAGATGCAGTCAATGGAGCAAAAACCCAGCGTGGAACAtgccagtggcagcagcaatagcagctgcAGTGGACACGCCACCACCAGCGTCATTCGCATGGccagcacaagcagcagcgcGAACTTGGCCACCGACGATCTCACACAGCCGCCGCCCATGAAGGTGGAGGTGGAGGCAACGGTGCTGATGCCGCAGCGCTTCTCAACGCCGGCGCAGCAGCGGGGCCCCAAGAAATTAGTCATCAAaccaaaggcaacagcaacggcgacggcaacggcaacgacgaATAAgactgacaacaacagcatcagcagcaactgcgcGGAAAGCTCCACCAGCATATCAAAGGTGGCCACGGAGCCGGTGCAGATCAAGAGCGAGAATGTGGAGACGGCCACAacgagtggcagcagcagcagcattctGGAGAAGCATCTGACCACCAGCTATGCGGCACAGCAGGCGCGCAAGCACTCGGCGGTCAATGATGACGATGCCCGCGTGCTGCTGGAGTTTGCTAATTCGAAGCAAATGCCTCTGGCTGGCAACAGCAATCAGACCACGTTTGTGGTGAATGCGGCCAGTTTTGCGTCGGCGGGCTCCGTgttcgccagcagcagcggcggcgctCAGAAGTCGACCAAGCCGGGCGAAGAGTATATTCTGCCTGATGATAACAATCTGGAGGTGGATGAAATTGTGATATCGTCCTCGTCTTCCTATGCCTCAaactcgcagcagcaacagcactcgcagtcgcagcagcagcagccgcagccagcgCAGCAGGTCttgcagcaggcgcagcagcctTCCGCCTTTACGGACTTTAATTTCCTGTACCATCCCAACGcgccaacagctgcagcagcaacaacggcggcTGCAGCAACCACTGCCAACTTTGCTCCATTTGGcatacagcagcaacagcagcagctgcaacatccCCACCACGGCTCCAGCGAAGCCACCAATGCCGCCACGCTGGCGTCCTCCTCCAGCAATTCATCCGCATTGGATCAGGATTGCTCGATGAATGCTACGTTTCGCATGgccaagcaacaaacaacgcTGAGCTCCTGGTATCAggcacatcagcagcagcagccgcaggcaACCACCTCCCACGCGTCTGGTGTGGAGCAGTCAAGTAATTTCATCGCCGCACTCGCAGCCGTCGATTGCAGCAGCGTGGCAGGTGTTGACAGCGATGCCAAGTACTTGGATCTGGATGCCTGCAAGCGTGAACAGctcagcaatagcagcagccaTTTGTCCTCGGGCTGTGCGTCCACGTCCACAACATCCTCATCGTTTGCAGCTGCGCCCACGGAGAGCAGTCTGGTTGGTGGCCTGGGTCTAAACATACGCACCGACGAGAAGATGCCCGCCAAGGGTGAGATCTCCGAGCAGGAGAGCAACTGCGACATCGAAAACTCCTGGAGTCAGTCGATGTACGGCGACATATCACAGCGTTACTTTAGAGGCCAGTTCACGGATGGCTATAATCAGCAGCTGGCCGATTGGCGGCACGACTATTATCCGGCGCAGGATCTTAGTGGCCAGCAGCAGTCACAGCGTGAGCAAAAGCGCTTTGATTTCAATGCGGTCGCCTCGGAATACGCGCAGCCAGGCGATCTGGACGCCACCTCGAGCTCAACTAGAAACAATCATTTGCTGGATGCACAGCCCACCACTTCCACGTCGTCGTCGGCTTTGCTGGCTGGTCCACCGATAGCCTCGACATCCCGTGCGGCCGCCGAGGCGGAAGCTGTGGCCGCGGCGTTGGCACAACGGAAGCCGCCGCGGCGCAAGATCTACAAGTGTCCGCACTGTGTGGCCATCTTTGAGAAGCTTAAGGAGCGCAACGCGCATTTGATCAGCGAGCATAACTATGTGCGCCAGAATCGACGTCTCATCTGCACCCTGGCGTCTCATCTCCCACAGACGCAGGCTCAACaggagccgcagcagctgcaacaacaacagcagcagcatctgatGTTGCAGGCGGGGCACACAAATGATGATGTCTTGCATGAGGACTCCAAGGATGGCATTGTGAAAATCAAGCAGGAGCACTGTCAGGATAAACAGGATTCAACGGAGCATCTGCTTGGCCACATGGAGTTGCCCGACGTCAAGGACTCGGGCCTGCTCGATGCCAGCGGCGAAAACGGTCACGATGCAGACATGAAGCCACCAACTAGCGTCACCGAGCTGGACGAGAAGCCCGCCATAGCGCCGTTGGCCATGACCACGCCCGCTGCCAAACTGGCCGCCCTCTATCGCATGCTAATTGCCTACAACGAGTCGAAACTGGGCCAGGAGCGCAACAATCTCAGCGAGCTGGAGCAGAAAGCCATGGAGAAATCCATATTCCTTTGCTATGTCTGCCGCACCGATTTCCCCTCCGTAAAGCTGTACGATGCACATCTCACTGAACATCCAGCCGAGTGTTTCACCTGCGGCAAGAAGTTCTATCGCTGGAAGAACTTCTCGCTGCATCTGAAACGACATCTGGGCTGGAAGGAGTTCGGCTGCTACGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCACTCGTGGAGCACATGCGCATGCACACTGGCCAGACTCCGCTCAAATGCAAGATATGCGGAAAGAAGTTCAAGCGTTATTCAAACTTGACGCAGCATCGCAAGCGTCACACCAAGATGATGGTGCGTAAGAAGGAGTACGTGTGCCACTGCGGCGAGGTTCTGCCCTCGAAGGCGCGCTTCCTGTGGCACAAAGAGACGCACGACTTGAAGCCCAAGTGCTGTCCGTATTGCTGCGATCGTTTTGTGCATGCGAACTCGCTGCGCCGGCATATTCGACTGGCCCATTCGGACAAGTTTGACTATGCCGAGCCCATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATCAAGGCGCACATGGCGACCCACTCGACGGATCCGCAATACGACTGCGCCATTTGCAATAAGAGCTTCTCCACCAAGTGGAATCTCAAAATACATTCGTGGGTGCATGCGAATCGCACAGCCAAACCGTTCAAGTGCGAGTATTGCCCGAAGGCGTTCGTGCGCGAGTTGGACTTCAAGAATCACATGAATGCGCACAAACAGATCAAGCCCTACACATGCGAGTACTGCGGCTGCAAGTTCATACGCAA
- Protein Sequence
- WANSEDENHGKLAHDHVEDGDDEHEDSRSRVGPKTTSKKSRKSKPNGKKHKRVAKHQPDDEDDFMSIGSSCAESDHQLEEQQPTQAHAAPAASASPSQLCTAPSTSSGAAAAAAAAGGSSGASSTTSGSIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPLDDYDSMRNAEMQSMEQKPSVEHASGSSNSSCSGHATTSVIRMASTSSSANLATDDLTQPPPMKVEVEATVLMPQRFSTPAQQRGPKKLVIKPKATATATATATTNKTDNNSISSNCAESSTSISKVATEPVQIKSENVETATTSGSSSSILEKHLTTSYAAQQARKHSAVNDDDARVLLEFANSKQMPLAGNSNQTTFVVNAASFASAGSVFASSSGGAQKSTKPGEEYILPDDNNLEVDEIVISSSSSYASNSQQQQHSQSQQQQPQPAQQVLQQAQQPSAFTDFNFLYHPNAPTAAAATTAAAATTANFAPFGIQQQQQQLQHPHHGSSEATNAATLASSSSNSSALDQDCSMNATFRMAKQQTTLSSWYQAHQQQQPQATTSHASGVEQSSNFIAALAAVDCSSVAGVDSDAKYLDLDACKREQLSNSSSHLSSGCASTSTTSSSFAAAPTESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRGQFTDGYNQQLADWRHDYYPAQDLSGQQQSQREQKRFDFNAVASEYAQPGDLDATSSSTRNNHLLDAQPTTSTSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPPRRKIYKCPHCVAIFEKLKERNAHLISEHNYVRQNRRLICTLASHLPQTQAQQEPQQLQQQQQQHLMLQAGHTNDDVLHEDSKDGIVKIKQEHCQDKQDSTEHLLGHMELPDVKDSGLLDASGENGHDADMKPPTSVTELDEKPAIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -