Basic Information

Insect: Drosophila melanica
Gene Symbol: Znf574
Assembly: GCA_004143765.1
Location: SCDT01000315.1:21511-23883[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.026 2.6 8.8 0.4 2 23 335 357 334 357 0.96

2 10 2.4 2.4e+02 2.7 0.2 6 23 367 384 367 384 0.97

3 10 7.5e-06 0.00075 20.0 0.8 1 23 390 412 390 412 0.98

4 10 0.00039 0.039 14.6 2.4 1 21 425 445 425 448 0.87

5 10 0.00019 0.019 15.6 1.4 1 23 456 479 456 479 0.97

6 10 2e-05 0.002 18.6 1.0 3 23 487 508 485 508 0.92

7 10 0.0022 0.22 12.2 0.4 2 23 520 542 519 542 0.97

8 10 0.00016 0.016 15.8 3.2 1 23 549 572 549 572 0.93

9 10 1.9e-06 0.00019 21.9 1.2 1 23 578 600 578 600 0.98

10 10 4.5e-05 0.0045 17.5 1.4 1 23 606 629 606 629 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.026	2.6	8.8	0.4	2	23	335	357	334	357	0.96
2	10	2.4	2.4e+02	2.7	0.2	6	23	367	384	367	384	0.97
3	10	7.5e-06	0.00075	20.0	0.8	1	23	390	412	390	412	0.98
4	10	0.00039	0.039	14.6	2.4	1	21	425	445	425	448	0.87
5	10	0.00019	0.019	15.6	1.4	1	23	456	479	456	479	0.97
6	10	2e-05	0.002	18.6	1.0	3	23	487	508	485	508	0.92
7	10	0.0022	0.22	12.2	0.4	2	23	520	542	519	542	0.97
8	10	0.00016	0.016	15.8	3.2	1	23	549	572	549	572	0.93
9	10	1.9e-06	0.00019	21.9	1.2	1	23	578	600	578	600	0.98
10	10	4.5e-05	0.0045	17.5	1.4	1	23	606	629	606	629	0.97

Sequence Information

Coding Sequence: ATGGCGGCGTGTGTGCTTTGTTTTGGGTGCTGCAAAAATGGCGATTCATATAAGATATTTTCCGAGGCTGGTTTGCGGCtcaatatttgcaaaacaataaacaaacatttttggctcGAGTTGAGCAGTGCAGGGAGCGAATACGAGGAAATTTGCCGCCAGTGCTGGGAGTGCGTAAGCAGCTTCAATGAATTTTACCAACGCGTCTACAACGCGCACCAGGAACGACGCTGCGACGTAAAGAATGTGCCCATCGAGTTCTGCGGCGATTCGGAGGCGGCCAATCCTCTTGCTATTGGCGGTGAATTGGATGCACTGGCCGAGGATTTCTTTGCATCCGACGATGTCAAGGTGGAGGTGAACGAGTTGGAGCCGCTGCCCAAGCTTGAAATTCTCGAGGAGCCCATAATTGAAGCAAAGACTGGTGCAACAAAGCGCGCTAGTGCCGACTATCCATCAAGTGCTAAGAGGCgtataaaaaaagagcaacTAACGGTCGTCAGTGATTCGGATGGGGACATACCGCTGGCCGAGTTCCTGGAACTGAAAAATACTTCAagggcagcgacagcaacagcttcgGCAGATAAACCGACATCCACCAAGGGCCGACAGCTACGTAGGAGCTCTCGTCGTGGACGCAGAGCGAAAACGCCGCCAGATTCACCGCAGGGCagcttaaaaaaagaatttctttCGGACGATGAGCgcgataatgataatgacaTGGATTTCGTGGCTGCTGAGGCAGTGCTGGGCACCGAAGACAGCGCCAGTTCCAGCGATCCCAGCGACAGCGACTCTGGCAACAGTTTGCCCGACGTGGAGCCAGAAGAGCGCTATGCAGAAATACCCAAGCGAGTTGTAGTCAAGCCCAAAAAGTATCGCAAACGTCCCAAGCCGCTGGTGGCTCCTGTTCGGATGAGTCGCGAGGAGATCGAGAAACGGAAAGCGCAACAAAACGAATTCGATGAGATTATCTTTGACTTTTTCAAGAAACTGCCATGCCACGTATGCAATCTGTTGGTGCCCAACTTCGGTGACATGCGTCGCCACCTGCGAATGTCCCACAATATTGAAAGTGGATTCATTGCCTGCTGCGGTCGCAAATTTCATATACGTCGGGGTCTGGCTGAACATGTGCTGGTGCACAAGAATCCAGAGCATTTTATGTGCACGCAATGTGGTCGCGTGTTCCAGGATTCCAAGTCACTCGAGACGCacgaacaaacacacacgaatCCTCAAGCGGATGCGAAGGATAAGCGCATGTACCAATGCGACAAGTGTCCCAAGTGCTTCACCACAAAGGCTGCTGTCGAGTACCACAATGTGTCCAAACATGTGCCCAAGTCAGACTTTAAATACACCTGCTCCGAGTGCAATAAGAAGTTGCCCACTGAGCGCAAACTGAAAGAACATCTTCGTTACATGCATGATCCGGAAACTGCCATCATCTGCGATAAGTGCGGCAAAACGTTGCGCTCCCAGGCCAATCTTAAGAAGCACCACGAACTGGAGCATTCCGATAAGCCACGTCCCAAGCCCGATCCAGTGCAGTGCGAGATTTGCGGCACTTGGCTGCGCCACTTATCCGGCCTTAAGCAGCACATGAGCACTGTTCACGAACCGCCCGGCGGTGAGCATCGGTGTCCCATCTGCGACAAGAAGTCCATCAACTCGCGCGCACTTAAACGCCATATCTACCACAATCATCAGTGCGAACGAAAGTTCCGCTGCACCATGTGTGAAAAGGCCTTCAAAAGGCCCCAAGACTTAAGAGAACACACATCCACCCACACGGGCGAGGTGTTGTACACCTGTCCGAACTGTCCACAGACGTTCTTCTCAAATGCCAACATGTACAAGCATCGGCAACGACTGCATCGCGCCGAATGGGAGGCGGATCGCAAGAAACCGCTGCCGCCCAACATAATGCAGCAAGCGGTGGGTGCCACATCGGCCATGAAGAAACGTCAGACTAACAATGCCGGCCCAGCGCTCTTTACACAATCCGCTGAGGCCATTGCGGATGTCCCGAAGCAGGAATCACAACTGCAATAg
Protein Sequence: MAACVLCFGCCKNGDSYKIFSEAGLRLNICKTINKHFWLELSSAGSEYEEICRQCWECVSSFNEFYQRVYNAHQERRCDVKNVPIEFCGDSEAANPLAIGGELDALAEDFFASDDVKVEVNELEPLPKLEILEEPIIEAKTGATKRASADYPSSAKRRIKKEQLTVVSDSDGDIPLAEFLELKNTSRAATATASADKPTSTKGRQLRRSSRRGRRAKTPPDSPQGSLKKEFLSDDERDNDNDMDFVAAEAVLGTEDSASSSDPSDSDSGNSLPDVEPEERYAEIPKRVVVKPKKYRKRPKPLVAPVRMSREEIEKRKAQQNEFDEIIFDFFKKLPCHVCNLLVPNFGDMRRHLRMSHNIESGFIACCGRKFHIRRGLAEHVLVHKNPEHFMCTQCGRVFQDSKSLETHEQTHTNPQADAKDKRMYQCDKCPKCFTTKAAVEYHNVSKHVPKSDFKYTCSECNKKLPTERKLKEHLRYMHDPETAIICDKCGKTLRSQANLKKHHELEHSDKPRPKPDPVQCEICGTWLRHLSGLKQHMSTVHEPPGGEHRCPICDKKSINSRALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQAVGATSAMKKRQTNNAGPALFTQSAEAIADVPKQESQLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508523;
90% Identity: iTF_00561207;
80% Identity: -