Basic Information

Gene Symbol
-
Assembly
GCA_037075325.1
Location
JBAMCG010000115.1:2231683-2233819[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 2.7e-05 0.0018 18.6 2.5 1 23 98 120 98 120 0.98
2 13 0.00035 0.024 15.1 4.1 1 23 126 148 126 148 0.96
3 13 2.2e-05 0.0015 18.9 0.9 1 23 154 176 154 176 0.98
4 13 0.00011 0.0078 16.6 0.0 2 23 200 221 199 221 0.97
5 13 1.6e-06 0.00011 22.5 1.7 1 23 227 249 227 249 0.98
6 13 0.0017 0.12 12.9 3.5 1 20 255 274 255 276 0.94
7 13 0.0097 0.66 10.6 0.4 1 20 414 433 414 435 0.94
8 13 0.00017 0.012 16.1 1.5 1 23 449 471 449 471 0.98
9 13 0.0052 0.35 11.4 4.7 1 23 490 512 490 512 0.98
10 13 0.00053 0.036 14.5 1.4 1 23 520 542 520 542 0.98
11 13 8.1e-05 0.0055 17.1 6.0 1 23 548 570 548 570 0.99
12 13 7.9e-07 5.4e-05 23.4 0.9 1 23 576 598 576 598 0.98
13 13 0.0039 0.27 11.8 2.7 1 23 602 624 602 624 0.95

Sequence Information

Coding Sequence
ATGAGTGGTATAATCGATCTGTCCTGTGTAAAAGTTGAGCGCGaccaggagctggagcagcagcaggaattcTATGGAATCTTGGAGGACGCCAAATGTGCTCAACTAAAAACTGAGCTGCCTTTCGCAGAGATGGACATAGGGCCTGTTAAAATAGATCCCGATGGATTGAGAGAAGAGCCAGCAGGCAAGGGGCAGATTAAGCAAAGAAGTGAGGCCCCGAGGACtcgcaagaagaagagagctgctgcagcagcagttgctgtttCTTCTACGGTTGCCAAAAAACAATATCAGTGCCGACATTGTCCACGGCACTTCGAACGCAGCGATGAGCTGAGCATCCACCTgctaatacacacacataatctCTCCTACAAGTGCTCCTACTGCCCTTACAGTTTTTCGCACAAATCCATCTATACAAACCACATGTATGGACACACAGGGAAATTTCCACATCAGTGCCCCGACTGTCCGCAgggatatatgaaatatgcggATCTGATGAAGCACCAACGCACGCACATTGTCAAGGATTTGAACAGGTGTCCCTTGTGCCCCACGAATTGCATACATAAGGGTAAGAATTTTCTTCAATGCCCGCAATGTCCGCGCGTCTTTGCCAATGGCTTCGAACTGGAGATTCATCTGCAGATCCACAGCAACAAGTTGCCCTACAAGTGTCCACATTGTCCGATCAGCTTTGGCCATAAATCGAATTATATAGCGCACGTTCGCGAGCATACGGGTCAATTTCCACATAGATGCTCGAACTGCCCGAAGGGATTTATGAAGCGCTCTGAGTTAACTAAGCACAAATGCGAAGGGTGGACCACTCCAAACAGAGCGAACATGAGGAAAAAACGTGGCATTGATAAGGAGGGTATGGAGCCAGTGGAACAACGCGAAGCGCTGCTAAAAAAGGAGCCAGTTAAGAGTCAGGctgcaagaagaagcagtccAAGAGTCAAAAGGCCTGCACAGGAATTGACAACAGCAGTGAGCACAAAGGAGCCCAGGAaagagaagcaggagcagcagcaatccaTAGCAAAAGACAGCACCTTAGCGAACCTGAATAGTAAAAATGATACAAAGCTGAGCTCTATCAAAACAGAACCGCAGGAGCAAGAAGAGCAGAGCAAGCCTAAGCAGGAGCCTATAAATGTTAACTCAAGGCTCGAAGTCAGGAAACCTATGCAGCAGCCCGTTGTAAGAATTAAGAGGCTGCGCAgccataaatgcaatttatgtaGCAAGGAATTACCCACATTAAACGAACTGCAAAAGCATGAAAAAGGTTGCGCTCCTTCCAGCAGGACAAATGAGGAATCAAATCTTTATGAATGTGAGCATTGCTCGAGGAAGTTCGCCCAGTTGCCTAGCCTTACGGAGCACAAACTCAGTCATTCGGCGAAACTTCCAGATAAATCCCCGCCTTCTATGCGCACAGTCAAAAGACCTTTTAAGTGTCCGCACTGTCCGTGCACCTTTGACAGCACTTTGAATCGGAAAAACCATTTGCAGATCCATCAACCCCAGAGCAATTATTCATACAAGTGTCTGCGTTGTGCACGGACTTACCAGCAGAAGTCAAATTTTCTGGCGCACTTGCGTGGACACACGGACGAACGCCCCTATCAGTGCACCTATTGCACGAAGGACTTCAAACACAGCGACGTTTTCAAGAAACATCTGCGCAATCATACGAGTGATCGTCCATATGTGTGTCCTCATTGCTCGAAAACCTTTGCGGAGAGCTCGGACTTCAATGCGCATCTACGTGAACATACAATACCCTACCAGTGTCCACATTGTCCGCGGCTCTTCCTTAAAGCCTTTAGCTACAAATTACATCTGCGCACCCATACGGGTGAAAAACCATGA
Protein Sequence
MSGIIDLSCVKVERDQELEQQQEFYGILEDAKCAQLKTELPFAEMDIGPVKIDPDGLREEPAGKGQIKQRSEAPRTRKKKRAAAAAVAVSSTVAKKQYQCRHCPRHFERSDELSIHLLIHTHNLSYKCSYCPYSFSHKSIYTNHMYGHTGKFPHQCPDCPQGYMKYADLMKHQRTHIVKDLNRCPLCPTNCIHKGKNFLQCPQCPRVFANGFELEIHLQIHSNKLPYKCPHCPISFGHKSNYIAHVREHTGQFPHRCSNCPKGFMKRSELTKHKCEGWTTPNRANMRKKRGIDKEGMEPVEQREALLKKEPVKSQAARRSSPRVKRPAQELTTAVSTKEPRKEKQEQQQSIAKDSTLANLNSKNDTKLSSIKTEPQEQEEQSKPKQEPINVNSRLEVRKPMQQPVVRIKRLRSHKCNLCSKELPTLNELQKHEKGCAPSSRTNEESNLYECEHCSRKFAQLPSLTEHKLSHSAKLPDKSPPSMRTVKRPFKCPHCPCTFDSTLNRKNHLQIHQPQSNYSYKCLRCARTYQQKSNFLAHLRGHTDERPYQCTYCTKDFKHSDVFKKHLRNHTSDRPYVCPHCSKTFAESSDFNAHLREHTIPYQCPHCPRLFLKAFSYKLHLRTHTGEKP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00551734;
90% Identity
-
80% Identity
-