Dmau013268.1
Basic Information
- Insect
- Drosophila mauritiana
- Gene Symbol
- ich
- Assembly
- GCA_004382145.1
- Location
- NC:20880092-20882359[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 2.4e-06 0.00015 21.7 2.5 1 23 134 156 134 156 0.98 2 10 6.4e-07 3.9e-05 23.5 1.5 1 23 162 184 162 184 0.99 3 10 7e-08 4.3e-06 26.5 3.0 1 23 190 212 190 212 0.99 4 10 0.019 1.2 9.4 1.9 2 23 219 240 218 240 0.90 5 10 1.9e-06 0.00012 22.0 1.7 1 23 246 268 246 268 0.99 6 10 0.0006 0.037 14.1 1.9 1 21 273 293 273 294 0.95 7 10 2.9e-07 1.7e-05 24.6 1.1 2 23 317 338 316 338 0.97 8 10 2.5e-05 0.0015 18.5 2.2 2 23 345 366 344 366 0.97 9 10 0.00032 0.02 15.0 0.8 8 23 379 394 372 394 0.93 10 10 0.00026 0.016 15.3 0.3 2 20 401 419 400 420 0.94
Sequence Information
- Coding Sequence
- ATGGAATCGTCCATATGCCGAGTTTGCCTGGTCAGCTGCGAAAATATGGCCAGTGTTTTCGATGCGTCTCATGAACCGGACCTATCCATTGCGTACATAATATCCAAGTGCACCGGCTGCCAAGTTGAGAAGGACGATCCACTGCCCAACACCATATGCCAGTCCTGTCTGGAGGATGCGCAGAACGCATTCGACATCATAGAAACGTACGAGAGAAGTCACCAGTTCTACCGCTTCTTCAAGGATGTTCGGGAGGAGGAGAGTGAAAATAAGGGATCCGGATGCTCAGAAGAAGTGAAGTCAGCTGAAATGGATCTCCAGGATGGTGCCGACGACGCCGATTCCGGCAATGAACCTGATACTAACGAACGTGATATCAAGGCCAAGGAGAAACCAGGCTTTAGCTGTTCTTACTGCTCGAAATCTTTTCAAATAAAATCGAGTCTGAAAGTACACTTGCGAACGCACACAGGAGAACGTCCTTTCACGTGCTCCTTCTGCCCCAAGTCCTTTGGCTACAACTCTGTTCTTCAGAATCACATGCGAACCCACACAGGAGAACGACCCTTCCAGTGCTCGCATTGTCCAAGGTCCTTTTCAGTTGCCCACAACCTCAAGGCCCACATACGGATGCACGAAAGAAGAGAATCCTTGAAGTGCCCATACTGCCAAAAGTGCTTTCTAAGTTCTTTAATTCTCAAGCAGCACTTGGCCACGCACACTGATAAAACGCAGTTCCAGTGTTACCAGTGCTCGAAGTCCTTTCAAGACGAACGGCAACTCCGTGTGCACATGCGAGTGCACCAAGAACGCCCCTTTAGGTGTTCCCATTGCTTAAAGGACTTTGCGCAACATGCGTATCTCAAGGCACACCTGTCAAGGAACGCAACATGCTCTCAAGGCTCAAAAACGTCTGCTCACAAAACACTAGTCCCCTCAAAGGCACTTAAGTGTGGTGAGTGCCCAAAAACTTTCACTGACCATTCGGCTCTTTTCGCTCACTTGAAAACGCACACCAAAAATAAGCCGCTGAAGTGTTCCCATTGCTCAAAGTTCTTTGCAAATCTTCAGGATCTAAGCCGGCACATAGTAACGCACACAGAAAACGGGCCGTTTAAGTGTTCCAGCAGCCCAAGGACCTTTTCGCGGAAATCAGCACTGCAAACACACTTACGAACCCACACAGGAAAACGCCCATTGCAGTGTTCCCACTGCCCAAAATCGTTTGCACGACGCTTAGGCTTTTGGGAACACATGCTGTAG
- Protein Sequence
- MESSICRVCLVSCENMASVFDASHEPDLSIAYIISKCTGCQVEKDDPLPNTICQSCLEDAQNAFDIIETYERSHQFYRFFKDVREEESENKGSGCSEEVKSAEMDLQDGADDADSGNEPDTNERDIKAKEKPGFSCSYCSKSFQIKSSLKVHLRTHTGERPFTCSFCPKSFGYNSVLQNHMRTHTGERPFQCSHCPRSFSVAHNLKAHIRMHERRESLKCPYCQKCFLSSLILKQHLATHTDKTQFQCYQCSKSFQDERQLRVHMRVHQERPFRCSHCLKDFAQHAYLKAHLSRNATCSQGSKTSAHKTLVPSKALKCGECPKTFTDHSALFAHLKTHTKNKPLKCSHCSKFFANLQDLSRHIVTHTENGPFKCSSSPRTFSRKSALQTHLRTHTGKRPLQCSHCPKSFARRLGFWEHML
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00592545;
- 90% Identity
- iTF_00592545;
- 80% Identity
- -