Basic Information

Insect: Drosophila mauritiana
Gene Symbol: ZNF526
Assembly: GCA_004382145.1
Location: NC:11760817-11763399[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.039 2.4 8.4 0.2 1 21 329 349 329 350 0.96

2 10 6.2e-07 3.8e-05 23.5 0.3 1 23 358 380 358 380 0.98

3 10 0.00025 0.015 15.3 1.0 1 23 383 406 383 406 0.92

4 10 6.2e-07 3.8e-05 23.5 0.8 2 23 413 434 412 434 0.98

5 10 2.9e-08 1.8e-06 27.7 1.0 1 23 440 462 440 462 0.98

6 10 2.1e-06 0.00013 21.9 1.2 1 23 468 490 468 490 0.99

7 10 0.00053 0.033 14.3 2.9 1 23 496 518 496 518 0.98

8 10 0.00089 0.055 13.6 0.3 1 23 524 546 524 546 0.98

9 10 8.3e-05 0.0051 16.8 3.7 1 23 552 574 552 574 0.99

10 10 0.0016 0.098 12.8 0.0 1 23 580 602 580 602 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.039	2.4	8.4	0.2	1	21	329	349	329	350	0.96
2	10	6.2e-07	3.8e-05	23.5	0.3	1	23	358	380	358	380	0.98
3	10	0.00025	0.015	15.3	1.0	1	23	383	406	383	406	0.92
4	10	6.2e-07	3.8e-05	23.5	0.8	2	23	413	434	412	434	0.98
5	10	2.9e-08	1.8e-06	27.7	1.0	1	23	440	462	440	462	0.98
6	10	2.1e-06	0.00013	21.9	1.2	1	23	468	490	468	490	0.99
7	10	0.00053	0.033	14.3	2.9	1	23	496	518	496	518	0.98
8	10	0.00089	0.055	13.6	0.3	1	23	524	546	524	546	0.98
9	10	8.3e-05	0.0051	16.8	3.7	1	23	552	574	552	574	0.99
10	10	0.0016	0.098	12.8	0.0	1	23	580	602	580	602	0.95

Sequence Information

Coding Sequence: ATGGATGTGGACAAGATCTGCCTGACCTGCCTGAGTTCCACGGGACCCCTCCTGTCCATCTACGACGGCGGATCCGGCAGCTGCCTGGCGGACATGATCCGGGAGTTCACAAAAACCAAGCCCCGACGCAACGATAATCTGCCCGAGAAGGTGTGCCTGAGCTGTTTGAGTGAAATCTCCAATTGCTACACGTTCAAGATCAAGTGCGAGAACTCCAGTCGCACCCTGCGCCAATTGCTGCCGAATGCGTTGCCGGAGGAGCCCGATAACAAGGTGTCTATCAGTTGTCCAGTGGCCACAACTGACCAGGCTGTGCAGACCACTAGTTGGGAGCCGGACAGATGCACAGCCTCCGTGCAAACGGACGCAGTGACTACCACAGACGCCGAGCAGAATACCAGCCTGATTAAGTCAACAATTTCAGTGGACCTGGACTACGAAGGCGAGGGCGAGGTCTTCGACTACGAGCTGCCGGATGAGCCCGTCGAAAAGACCACCAGCCTCATCCTGCAGGTCCAGGGAAACTTAAAGGACGAAAAGGAAGTGGTGTTTACCCAAACCAATGTTATTTACGAAGGCGACGCCCACGAGCTGGAACAGCAGATCAGGGAATGTAATCTGGCCATCTTCGAAGGTGTCGACAACGAGGCGGAAATCATCACAGTAACCGCTCCGCAGGTAACCACCAGAAAGAGCGCTGCCAAGCTGCTAACACAGCAGGAAAACGATAAGCAGGAGACTCGTGTGGGTTCCAAGGAAGAAGCACGCGAAATAGAGAAGGAACAAGTACCTCAGACGGCTAAGCGCACCTCACGGCGTCGCGGAGGTGTCAAGCAGGATGTACCGGCTACCCCGCCGTCAGATACAGAGCCTTCCCCCAAGCAGCATCGGTTAGGAACGCAGCGAAAACTCAGCGCGCCAAGAGCGGGAACAGTAAACAGCCCTAGCACAACGTCAGGAGCAGCCACTACCCCTGAGCTCAAATACCACTGTGATCGTTGCAATGCGGGATTCGCAGTAGAGAAATCGTTGATGATCCACAGACGCCAAAAGGGCTGCATTAATCGCAACTTCAAGTGCAATGAGTGCGAAAAGGTCTTTGTGTCGCCGGATCACTTGGCGGAACACCAGGCCAGTCATGGTGCCCACAATTGCCCGGAGTGTGGAATACGCTGTGATTCCAAGGAGGCACTGAGCAAGCACATGGTGCAGGGCCACAAGCGTAATCTGCGGAATCAGTGCAATATCTGTCAGAAAGTATTCACCATGCTGTCCACGCTGCGTGACCACATGCGCATCCATACTGGCGAGAAACCCTTTGTGTGCAATATCTGCGGCAAGAGCTTTACACAGAACGCCAATCTTCGCCAGCACAAGCTGCGTCACTCGGAGACCAAAAGTTTCAAGTGCGAGCTGTGCCCGCACTCGTTCGTTACCAAGGCGGAACTCACCTCCCATGCCCGCACCCACACCGGTGACAAGCCCTTCGAGTGTGAGGTGTGCTTGGCCAGATTCACCACCAGTTGCTCCCTGGCCAAGCACAAACGAAAGCACACAGGCGAACGGCCATACGCCTGCGATCTCTGCCCCATGAGATTCACTGCCCTCAATGTGCTAAAGAACCACCGAAGGACGCACACAGGTGAGCGACCGTACGTCTGCCCCTTCTGCTCAAAGACCTTTACGCAGCGGGGTGACTGCCAGATGCACCAGCGTACACATCAAGGCGAGCGGATCTACATTTGTCCGGTGTGCAATGAGGAGTTCAAGTCGATGCCCGAGATGCGATCACATTTGGCCGGCCACGAGCAGCACGACAAACGTCTGGTGCACTTCACCTTTCTGAGCAACAAGGAAAACGGAAGCGGGGCCCTTGAAGAAGACCTTAACGAGATAACCGAGTCTGCACTTATGCTATAA
Protein Sequence: MDVDKICLTCLSSTGPLLSIYDGGSGSCLADMIREFTKTKPRRNDNLPEKVCLSCLSEISNCYTFKIKCENSSRTLRQLLPNALPEEPDNKVSISCPVATTDQAVQTTSWEPDRCTASVQTDAVTTTDAEQNTSLIKSTISVDLDYEGEGEVFDYELPDEPVEKTTSLILQVQGNLKDEKEVVFTQTNVIYEGDAHELEQQIRECNLAIFEGVDNEAEIITVTAPQVTTRKSAAKLLTQQENDKQETRVGSKEEAREIEKEQVPQTAKRTSRRRGGVKQDVPATPPSDTEPSPKQHRLGTQRKLSAPRAGTVNSPSTTSGAATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNFKCNECEKVFVSPDHLAEHQASHGAHNCPECGIRCDSKEALSKHMVQGHKRNLRNQCNICQKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHQGERIYICPVCNEEFKSMPEMRSHLAGHEQHDKRLVHFTFLSNKENGSGALEEDLNEITESALML

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505549;
90% Identity: iTF_00591836;
80% Identity: -