Basic Information

Insect: Drosophila malerkotliana
Gene Symbol: Hivep2
Assembly: GCA_018153235.1
Location: JAECXV010000075.1:11271581-11279733[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00064 0.047 14.0 0.2 1 23 187 209 187 209 0.98

2 8 0.0056 0.41 11.0 2.1 1 21 215 235 215 239 0.88

3 8 0.0096 0.7 10.3 0.1 1 19 821 839 821 842 0.93

4 8 2.1e-06 0.00016 21.8 2.0 1 23 1535 1557 1535 1557 0.99

5 8 7.8e-06 0.00057 20.0 3.5 1 23 1563 1587 1563 1587 0.92

6 8 4e-05 0.0029 17.8 3.6 2 23 2042 2063 2042 2063 0.97

7 8 0.00061 0.045 14.1 1.2 1 23 2069 2093 2069 2093 0.91

8 8 0.002 0.14 12.5 2.7 1 23 2114 2138 2114 2138 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00064	0.047	14.0	0.2	1	23	187	209	187	209	0.98
2	8	0.0056	0.41	11.0	2.1	1	21	215	235	215	239	0.88
3	8	0.0096	0.7	10.3	0.1	1	19	821	839	821	842	0.93
4	8	2.1e-06	0.00016	21.8	2.0	1	23	1535	1557	1535	1557	0.99
5	8	7.8e-06	0.00057	20.0	3.5	1	23	1563	1587	1563	1587	0.92
6	8	4e-05	0.0029	17.8	3.6	2	23	2042	2063	2042	2063	0.97
7	8	0.00061	0.045	14.1	1.2	1	23	2069	2093	2069	2093	0.91
8	8	0.002	0.14	12.5	2.7	1	23	2114	2138	2114	2138	0.92

Sequence Information

Coding Sequence: ATGGAACTAAAATCGAACGGGAGGGAGGCCTTACTTACCGCCTTTGGGGAGTGCTCAAACATATCGCGATATTTGCACAAGAAATTCAAGCGACTGGCCAGCACCACCGAGGTGGAGAACGCCAACGGTAATGGCACTCTGTCTGGGGATGCCGGCCGCACCACATCGCTGTCCTCAAATAGCTCACTTTCGCCTCCGCCACCGCCACCGACAATGGTCGCCAATGGTCATCACTTGACCCAACAGCCGTCGGTTGCGCAGCCAGTGCCGCTGTCGACGCAGCAACATGACTTTAGTGCCAACTTTGTAAATAGCAATCATGTCAATGCCATCGGCCAGGCGGAGGAGAGCCAGAAGGCAGTGCCCAGAACGCGAACACCGCTCACCAACAGCAACAGTAACAGCAATAGCAACAGCAACTATGCGGCAAATGCCACACTGTCGCCGGCAACATTCGCTCAGCACCAGCAGTTGACGCAGCCAACGGCACCGGCTGGCGGAGGAGTGCCAGGTGGAGGAGGAGGAGGAGGTACTCCCGCTGGTGAGAAGGCCGGACGTTATGTCTGCCCGTATTGTAGTTTGATTTGTGCCAAGCCCTCGGTGCTGGAGAAGCACATCAGGGCCCATACCAACGAGCGTCCTTATCCCTGCGATCCCTGCGGTATTGCCTTCAAAACGAAGAGCAACCTCTACAAGCACTGCCGCTCCAGGTCGCATGCGGCCAGAGCCAGGGGCTTGGAGGTGCCGCCAGATGCGGATGATGGTCTGTCCGACCAGGATGCCGAGCTGAGCAATAGTAGTTCCGAGTTGCCAAGTCGCGCTGGATCGCCATATGACGAGCCCATGAGCTCGCCCACACCCTCACCCTCCACACTGTCGGCGGCAAAGAGCGCCTACATCCAGCAGCCGTCACTCCCGCAGCACATGCAACAACTGCCGCTGGGTTCGCCGGCCGCGGGGACACTACCGCCCGCCACGGCGGACAACCTGCACTCGGCCACTGCCCAGCACCGCCAGTCGGTTGACTACAAGCCATACAAGCCCAAGTTCCACAATGCCTCGCTGTACGCTCCCGGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTCTCGCCCAGCACCCAGATGAAGATGAAGAACCACATCAACTCCCACCAGATGCAGTTGCAGCTGCAGCAGCAGTTGCACGCTCAGCAATCGCTGCTGGTCGGCCTGCCGCCGGTTCCCCCAGCCGGGGTCTACTACCTGGGCCAGCCACCCTACTACAATCAGGATCCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGGTTAAGGCTCCTCCGCCAATGGTACAGCCACCCAGTGTCGCCCCTCAGCAGCTGGTGCGGACCAACAGTCAGGTTTCCAACGTAACCCCAGCGCCAGCCACTCCCTCGCCCGCCACGAACCTGAGCAGCTTTGCCAGCTCCAGCGGGGGCATGCAAGTGAATGTGGCCAAAGTTCAGGAGCACATATCGAAGCTGATCTCGCACAACGAGGCCATTGTGGAGAACAAAGACATACTGCTGCAGAAGAAGTATCCCAAGCAGCTCAACCGATCCCGCAGCTTCAACAACGCCAACGCCAATAGTGCGTCGCAACACGCCGGAAACCCAACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGGAACCTCCTAATGGGTTGGTCAAGAGGAACAATTACAAGCCAGCTCCGGCGATTGCCACGCCAGTGAAGCAGCAGCCCCATCTGCCACCTCCGCCCTCTCCACTGCCCATGCAAACGATGCAGTATCGTCAGGATCCCGCCACTCCGGTGGCCAAGATCGACCAACAGGCGATGGGAGGGCATGTGATGCCCTTGAACCTGTCGGCGAAACCAAAGCCCGCTGTAGTTAGTCTGCCGGTCAGTTCCATAGCCACCAGCACGGCGGCACCGACGCCCACGAGCTCCACGGCTCCGGCGGCCAGCGGCTCGAAAACTGCCCCACCCACTGCCCAGCCCAACAACTCAATCATCAAGAACCTGCTGCTGAACGCCCGAGGACTGGCCGTGCCCATTGGAGAGGGCGACGACGCCGTCTACTCCTGTCCCATTTGCGCCAATGAGTTCCGCAGTGCGGACGAGCTGAAGCAGCACAACAGCACCTATTGCCAGGACGCGAGCTCCAGTGCGCCGATGAGTCCGGCCTCCTCGCCCTTCCGCTCCAACTCGATCTCGCTCAGCCTGCCCGAGCTGAAGAACCACATCGCCAACTCCAAGAACCCTCTGTCGCTGGCCAAGCTGGCCTGGTGTCAGCTGAAGACCAAGAGGAGCTGCCTGGTCCTCAATCGCCTAAATGCAGCCCAGACCCACGCGAGGACTTCCACGGTTACTGCTCCTACAGCTACTCCTCCGGCAACTGTTCCTGCTGCGGCTAGCTCTTCCAGTGTGGCTCCTTCTCCTTCAAGTGCTCCAGCAGCTCAGCCCATAGTAGCTCCCACAGCCATCGAAGCTCTGCGCTTTGTGGATGCCCCACTGCCGTCTCCCGGACCACTCCTGGGAAAAACCCCACTGGTGGACTATGCCCAGCAGAACACGCCCCGCAAGGCCCAGGACTCCGTTGTGATTACGAAGATGCACGAGGATCGGCAGTTCCCCGTGGACATGGACGCTCAGCCGGCCAAGCGAGTGAAGACCAGCGATGTCGTCATCGTTCCCTCCCAGACTCAGGCGCAGGTCTTCACCTTTCCCTACAGCAGTGTTTCCGAGCCGCAATCCAGCAAGGAGGAGCGCCTGCGAAGACTGACTTCTTCTGGAGGCACTATGATTCCCATATCGGAGTGCCCCGAGCTGGAGAAGAGTCCCAGGGTGATACGCACATCACTGCTGTCGGGCGGAAGCTTCCAGGAAGTCGGAACCGCCTCCAAGGTCAGCGAGCCTGGATCGGCCAAGGACCGAAAGCTACTACCGTTGCCCGGAGGCCTCTCCACGGGCGCCCAGCACTTTCAGTTCCCGCCCATCAACTCCATCACTGCCTTCAACCCCCTGACCCTGCCGCAGATGGGTGGTGGCGACAAGGCTACTCCAAGCACACCGATTCCCTACGTGCCTGGAATCCCGGGACCTGGCAGTCTGACTCCCCAGATGCCTCTGCTCCCGCCGCCGCCGCAACAGTTGCAGTTGCCGGTGCCCACTGGCCGGGGACGCAGTCCCAACCGGAAGCAGCCCAGCCCGCTCTTGATGGCCGGCGCAGCTGCTGGCGAACTGAAGGCCCTGTCTCCGTTCGGCGGAGTTCAGAATCTCCCCAGCGAGTTCAGTCGCCTTCCGCCCACTCCCGCCCAGCGCCAGGCCCTCCAGTGGAACAGCAAGGAGGCCAACAAGAAGGCTCCGTTCAACTTCCTCCGAATGGCCGACAACGTAAAGATCGCCGAGCCGGAGGTTCGTCACTTCAATCTGGACAACGTGATTGCCGGCAAGCAGCAGCAGGAGGCGCCTCTAACGCCCCTGCACGTGGACACGCCCAATGGAGTGGCCAGCGAGGAGGCCAATGCCCCGTCCACCTCCAGCTCCTCCGCCAAGTCAAAGTTCCTGCGACCCACTAGTCTGCCCCTGAAGCCGGGAACCTTCACCCCGAAACGCCATCACGGAATCACTCCCACGGCCAACACCCTGCCCCTCATCTCGCCCGAGACCCCGAGGCCATCCAAGTCCTGCGTGCAGCTGTATCTGAATGGGCACGCCTACACCTACCTGGGGCTGAAGTGCAGCACCAAGATGTTCTACTGCACGGTGAACTGCCCGCAGCCCTCGTACGTGGCCGGCATGCACAAGCTGTCGATGTACAGCGTGTGGCAGGTGTGCGAGGAGAACCAGCCCCATCCTCTGGGCTTCAAGCTGAAGCAGGTGATGGCCCTCTACGACTCCCGCCAGAGGATGCTGGGCAACGTGAGCACCACTGCGATGGCTGGAACTGGGAAACTGAGCTACGGCCTGGTATCGTCCCAGCAGATCGTGTGCTCGCCCTCGACGAATGCCAGCAGCAGTGCCTTCTACCAGGCCCAGCAGAAGTCAGCGCCCGCCGTCCAGGTGGCCGCACTCAGCGAGGCGAACGTGGCGGCCAAGGCGGCTAACGATGAGGCGCAGGCCAAGAAGCTGGAGACCAGCCCCTCCGGCCAGCCGCTGGTGGGCGGATACGAGTCGCACGAGGACTACACCTACATCCGGGGACGCGGACGTGGCAGGTATGTCTGCTCCGAGTGCGGCATTCGCTGCAAAAAGCCTTCCATGTTGAAGAAACACATTCGTACTCATACGGATGTGAGGCCTTTTACATGCAGCAACTGCAATTTCAGCTTCAAGACCAAGGGGAACCTGACCAAGCACATGCAATCCAAGACGCACTTCAAGAAGTGCATGGAACTGGGCATCAATCCAGGACCCATGCCCGCCGATGGCGAGTTCTTGGATGTGGACATGGACTTTGATCAGCAGTCGTCCACTTCGGCCGGAGGACGCACCTCCTCGATGGCCGGGGAGTCCGACTCCGATGACTTCACCGACAATGAATCGGAAAGTAGTGACACGGATGAGTCAAAGTCGCGCCTGAAGGAGCACGAGGCAGCCAGATGCCTGCTGTCGCTCTCCATGACGCCGCCCATTCCGCAAAGTGTCTCTCCTTATCCGCAACTGCAGGATACACCTGTTCCGGCCGCCAGCCCGGCCAACAGTATTGGATCTTCGGGATCGCTGCCGAAGCGATTGGTGTGCTCCTTCACCTCCCCGAAGCCTCCGTTCGACTATCAGAAGCAGGAACAGTATTACTCCAATCCGGAGGAGTCCAAGCCGAAGCGAAGCGTGGCCAGCGAGGAGAGCGCCCCCATGGATCTCACCAAGCCGCGTAGCTCCACGTCGGCCATCTCGCCCTTGCCGCTGGTGCCGCCAGTGCAGGATCTGCCCAAGTCGCAGGCCCAGCAGATGCGCGAAGTAATCTTCGGCAGCTCCGGCAACGAGAGCGGCTTCATGAAGACCCTGATTTCGGTGTCGGACAAGGTGCGCATCTCGGCCGAGATGGAGGAGCAGGCCAAGCTGGGGGCCGAGGGCGAGGACGTTCTGCTGCAGACGTACATCAAGGAGCAGGCGCTCCACCACGCCAAGATGAAGCAGAGCCAGTTCAGCCGCAGCTACCTGATCAACACTCTGTTCTCCACGGCGGCGCCGGTGATGAGCAGCAGTGCCAACCTACTGACCACCACCAGCAGGCCAGTCATGAGCATCAACGAGGTGCCCAGCATCGAAGTGCACGAGGTGAAGACGCCGGACGAGGTGCCCGCTGTGGCTCCTGCTATTCCGGCTCCAGCATCAGCCCCTCCTACCTCAGCGGTACCTCCCGTGGCCGTCGCTTCTCAAGAGGAAGGCGAGGAGAGCGACCACGAGAAGTCCAAGGTGGAGCGTCACAATGCTAACCTGCCCGCCGCAGTGCAACAGCCGGATGTCAATGACTTCAGCGGAGTACTCAGTGGCCCATCCTTGGCCACAACAGCACCTCCTGCCTCCGTGGCTACGTCCACTCCTGCACCTGTGGTCACATCCAGCACAGCCACCACTCCCAGCGTGTCGTCTCAGCCCACGCAGCGCACTGTGATTGTGGGCGAGGATGGATTCAAGAACTCCACGCCCAGCAGCAAGAGCAGCGACCTCCAGGCGGGTCCCTACGCCCGCGGAATGCCACCTGCTCCCCCGCCAATCGCAGCCGACGCCCGACCCACCTGCACCATCTGCTCCAAGACGTTCCAGCGGCAGCACCAGCTCACCCTCCACATGAACATCCACTACATGGAGCGGAAGTTCAAGTGCGAGCCGTGCAGCATCTCCTTCCGCACCCAGGGCCATCTGCAGAAGCACGAGCGGTCCGAGGCGCACAAGAACAAGGTGATGATGACCTCGACATTCGGAGTACCCACCACCTCCAATCCGCGTCCCTTCGAGTGCACCGACTGCAAGATCGCCTTCCGCATCCACGGGCATCTGGCCAAGCATCTGCGCTCTAAGACCCATGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCATTCGGAACCTACGCGGAGATCGAAAGGGCTGGCATCAGTCTCACGGAGATCGACACCAGCGACTGCGAAAACTCGCTGATTTCCTTGAAGCTACTGGCCCAGAAGCTGCTGGAGAAGGATCCCAACAAGCTGAGTGGCTACACCACCCCCTCGGGAATGATGCAGCTGGCCCAGGACGGCACTGGCCCCACCTCGCAGGATAGTGCCTCCGAGGATGGCTTCAGCGCGGCCATAGCCTCGGCCATTGCATCCCTGGACAACGATAGTGCTGGAAACACACCGAAGCGTGCCAGCTCCATGTCCGAGGACGAGACAGTGACCAATGGCCTGAACCACAATCTGAAGCGACGCTTGCCGGGAAGCTTCAGCAGTACCGGCGAGGAGAGCGATAATCCGGCAGAGGGCACTGGCGAGAAGCGGGCGCGATCCGGACAAGAGTTGCCGGTTCCGGTGCCTGTGGCTGTTCCGGTGGCCGCCTCAGCGGCAGCCAGCAACTGA
Protein Sequence: MELKSNGREALLTAFGECSNISRYLHKKFKRLASTTEVENANGNGTLSGDAGRTTSLSSNSSLSPPPPPPTMVANGHHLTQQPSVAQPVPLSTQQHDFSANFVNSNHVNAIGQAEESQKAVPRTRTPLTNSNSNSNSNSNYAANATLSPATFAQHQQLTQPTAPAGGGVPGGGGGGGTPAGEKAGRYVCPYCSLICAKPSVLEKHIRAHTNERPYPCDPCGIAFKTKSNLYKHCRSRSHAARARGLEVPPDADDGLSDQDAELSNSSSELPSRAGSPYDEPMSSPTPSPSTLSAAKSAYIQQPSLPQHMQQLPLGSPAAGTLPPATADNLHSATAQHRQSVDYKPYKPKFHNASLYAPGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLSPSTQMKMKNHINSHQMQLQLQQQLHAQQSLLVGLPPVPPAGVYYLGQPPYYNQDPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVKAPPPMVQPPSVAPQQLVRTNSQVSNVTPAPATPSPATNLSSFASSSGGMQVNVAKVQEHISKLISHNEAIVENKDILLQKKYPKQLNRSRSFNNANANSASQHAGNPTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEPPNGLVKRNNYKPAPAIATPVKQQPHLPPPPSPLPMQTMQYRQDPATPVAKIDQQAMGGHVMPLNLSAKPKPAVVSLPVSSIATSTAAPTPTSSTAPAASGSKTAPPTAQPNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKQHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKNHIANSKNPLSLAKLAWCQLKTKRSCLVLNRLNAAQTHARTSTVTAPTATPPATVPAAASSSSVAPSPSSAPAAQPIVAPTAIEALRFVDAPLPSPGPLLGKTPLVDYAQQNTPRKAQDSVVITKMHEDRQFPVDMDAQPAKRVKTSDVVIVPSQTQAQVFTFPYSSVSEPQSSKEERLRRLTSSGGTMIPISECPELEKSPRVIRTSLLSGGSFQEVGTASKVSEPGSAKDRKLLPLPGGLSTGAQHFQFPPINSITAFNPLTLPQMGGGDKATPSTPIPYVPGIPGPGSLTPQMPLLPPPPQQLQLPVPTGRGRSPNRKQPSPLLMAGAAAGELKALSPFGGVQNLPSEFSRLPPTPAQRQALQWNSKEANKKAPFNFLRMADNVKIAEPEVRHFNLDNVIAGKQQQEAPLTPLHVDTPNGVASEEANAPSTSSSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQVMALYDSRQRMLGNVSTTAMAGTGKLSYGLVSSQQIVCSPSTNASSSAFYQAQQKSAPAVQVAALSEANVAAKAANDEAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSNCNFSFKTKGNLTKHMQSKTHFKKCMELGINPGPMPADGEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDFTDNESESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYPQLQDTPVPAASPANSIGSSGSLPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVASEESAPMDLTKPRSSTSAISPLPLVPPVQDLPKSQAQQMREVIFGSSGNESGFMKTLISVSDKVRISAEMEEQAKLGAEGEDVLLQTYIKEQALHHAKMKQSQFSRSYLINTLFSTAAPVMSSSANLLTTTSRPVMSINEVPSIEVHEVKTPDEVPAVAPAIPAPASAPPTSAVPPVAVASQEEGEESDHEKSKVERHNANLPAAVQQPDVNDFSGVLSGPSLATTAPPASVATSTPAPVVTSSTATTPSVSSQPTQRTVIVGEDGFKNSTPSSKSSDLQAGPYARGMPPAPPPIAADARPTCTICSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMMQLAQDGTGPTSQDSASEDGFSAAIASAIASLDNDSAGNTPKRASSMSEDETVTNGLNHNLKRRLPGSFSSTGEESDNPAEGTGEKRARSGQELPVPVPVAVPVAASAAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00550443;
90% Identity: iTF_00580185;
80% Identity: -