Basic Information

Insect: Drosophila malerkotliana
Gene Symbol: -
Assembly: GCA_018153235.1
Location: JAECXV010000036.1:563246-565022[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 6.5 4.8e+02 1.4 4.0 2 23 206 230 205 231 0.83

2 10 0.18 14 6.3 0.5 6 23 240 257 240 257 0.99

3 10 0.0064 0.47 10.9 1.0 1 23 263 286 263 286 0.97

4 10 1.7e-05 0.0013 18.9 1.1 1 23 294 316 294 316 0.97

5 10 6.7e-07 4.9e-05 23.4 3.3 2 23 323 345 323 345 0.98

6 10 3.8e-05 0.0028 17.9 1.2 1 23 352 375 352 375 0.97

7 10 0.043 3.2 8.3 0.6 2 23 385 406 384 406 0.96

8 10 0.015 1.1 9.7 0.4 2 23 416 437 415 438 0.94

9 10 8.8e-06 0.00065 19.9 3.6 1 23 443 465 443 465 0.98

10 10 0.0001 0.0074 16.5 3.7 1 23 471 494 471 494 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	6.5	4.8e+02	1.4	4.0	2	23	206	230	205	231	0.83
2	10	0.18	14	6.3	0.5	6	23	240	257	240	257	0.99
3	10	0.0064	0.47	10.9	1.0	1	23	263	286	263	286	0.97
4	10	1.7e-05	0.0013	18.9	1.1	1	23	294	316	294	316	0.97
5	10	6.7e-07	4.9e-05	23.4	3.3	2	23	323	345	323	345	0.98
6	10	3.8e-05	0.0028	17.9	1.2	1	23	352	375	352	375	0.97
7	10	0.043	3.2	8.3	0.6	2	23	385	406	384	406	0.96
8	10	0.015	1.1	9.7	0.4	2	23	416	437	415	438	0.94
9	10	8.8e-06	0.00065	19.9	3.6	1	23	443	465	443	465	0.98
10	10	0.0001	0.0074	16.5	3.7	1	23	471	494	471	494	0.97

Sequence Information

Coding Sequence: ATGATATGCCGCCTGTGTCTGGACGAGGCGGAGCACAGTGTGCCGATCTTCGACCAGGACGATGCCGCCGACTTCGCTGGGGCCTCCACCAACTTGGCCGGGCTGATTGAAAAGCACCTGCAGATGGTGCTCCTGCCCAATGACGCGGTGTCCAAGTGCCTCTGCACCCAGTGCTGGCAGCAGTTGGCCGATTTCGAGCAGTTCTGCTCGATGGTGATGAAAAAACAGCTGGGCCTGCCGCAGCTGAAGCAGGAACCCTTTTCCGAGGACGACGACGACGACACCAAGGCGCAAATTCTGTGCGAGCCAGAGATCGATGTTAGTCCGGCAGGGCCGGACACTGAGGAGTTCAACGAGATCGACGTGGATGCCAGTAGTAGCCAGGCAAAGGGAAAAGTTCGCCTGCCGTCGCCCATACGGCGCAGTATGCGTCCCCGGTCTGCTCCAAAGACCAGATCAGTTAAGAGCAAGGTCAAACCCAAGCGGCAGCCGGTGGAGGAGGATGAGGACGGAGACGAGGATGAGGAGCGAGAAACAGATCCAGCGGTGGACGCTGAGAGCCGCACCAGCAGCAGTCATGAAATGGACAGCTACATTGCGAGTCATGGGCGTTTGGAGTGCAATCTGTGCGGCAGTGACGACGGCCAGTTCCAGAACTTTGCCGAACTGAAGCGCCATTTCCGCAATCACCACCAGTCCCAGGGATATGTGGTGTGCTGCCAGCGGCGCTACAAGAAGCGGGCTCTCTACGTCGACCACCTGCGCATGCACAACGATCCGGACTACTTCAGGTGCAAGATATGCTCCAAGCAGCTGGTGAGCCGGATTAGCTACGACGTGCACATGCTGCGCTTCCACTCCAATGACGAAGCCTGTGTCTTTGCCTGCGACAAGTGCTCCAAAAGATTCTCCAAACAGTTTCTGCTCACCATTCACGCCCGGGTGCACCAGCAGGAGCGCAAGGAGCAGTGCAAGCACTGCGACAGATCCTTCCGCACTGCCGTGGATCTGCGGCTACACATGCGTCGCACCCACGATCCCAGTTTTGTGCCCTTCATATGCGACTCGTGCGGCTCCAAGTTCAAGACGAAACAGAATCTATTGGTGCACAAGCGAACCGTGCATCGGGAGGGCTCCCAGCTGCCGGAGGTGCAGTGCCAACAGTGCCAGACATGGCTGAGCGACGAGAACAGTCTGCGCAAGCACATGTACATGCATCTGGACGCTGCATCGCTCCGGCAATGGAAGTGCGAGCAGTGCGGCCTCGTGAAGGACTCCAGGGCCAAGTTGGCTGCCCACATTCGTTACCACCATCCAAAGGAGTATCACAAGTGCTCCCACTGTGGCAAGGAGTTCAAGAGCAGTCGAGGCCTGGAAGAGCACACAGCCACTCATACGGGCCAGGATCTGTACGAGTGCGCCTTCTGTGAAAGGACTTTCAAGAATTCGGGTAATATGCACAAGCATCGCCGCCAGATGCACGCTGCCCAGGTGGCTGCCCTGCAGCAGCAGAAGAAAGTGCGCCCCAGCAAGCGGAAAGACAAGGGCGAGCTACTGCTTGGTGTCCTGGCATCTTCCGGCGGCAAGGACATGGACATGGACGTGGGGATGGGCATGCCAATGGGAATGGGAACTGTGGGAGGGAGTGGAGTAAACGACTGA
Protein Sequence: MICRLCLDEAEHSVPIFDQDDAADFAGASTNLAGLIEKHLQMVLLPNDAVSKCLCTQCWQQLADFEQFCSMVMKKQLGLPQLKQEPFSEDDDDDTKAQILCEPEIDVSPAGPDTEEFNEIDVDASSSQAKGKVRLPSPIRRSMRPRSAPKTRSVKSKVKPKRQPVEEDEDGDEDEERETDPAVDAESRTSSSHEMDSYIASHGRLECNLCGSDDGQFQNFAELKRHFRNHHQSQGYVVCCQRRYKKRALYVDHLRMHNDPDYFRCKICSKQLVSRISYDVHMLRFHSNDEACVFACDKCSKRFSKQFLLTIHARVHQQERKEQCKHCDRSFRTAVDLRLHMRRTHDPSFVPFICDSCGSKFKTKQNLLVHKRTVHREGSQLPEVQCQQCQTWLSDENSLRKHMYMHLDAASLRQWKCEQCGLVKDSRAKLAAHIRYHHPKEYHKCSHCGKEFKSSRGLEEHTATHTGQDLYECAFCERTFKNSGNMHKHRRQMHAAQVAALQQQKKVRPSKRKDKGELLLGVLASSGGKDMDMDVGMGMPMGMGTVGGSGVND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00566302;
90% Identity: iTF_00615709;
80% Identity: -