Basic Information

Insect: Drosophila malerkotliana
Gene Symbol: wdn
Assembly: GCA_018153235.1
Location: JAECXV010000008.1:2192763-2195534[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 4.6e-05 0.0034 17.6 0.3 1 23 313 335 313 335 0.99

2 7 0.047 3.4 8.1 1.8 2 23 346 366 345 366 0.93

3 7 5.1e-07 3.7e-05 23.8 1.1 1 23 372 394 372 394 0.99

4 7 3.2e-06 0.00023 21.3 4.0 1 23 400 422 400 422 0.98

5 7 0.00017 0.012 15.8 3.0 1 23 428 450 428 450 0.97

6 7 4.1e-06 0.0003 20.9 0.8 1 23 456 478 456 478 0.96

7 7 7.6e-05 0.0055 16.9 2.3 1 23 484 507 484 507 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	4.6e-05	0.0034	17.6	0.3	1	23	313	335	313	335	0.99
2	7	0.047	3.4	8.1	1.8	2	23	346	366	345	366	0.93
3	7	5.1e-07	3.7e-05	23.8	1.1	1	23	372	394	372	394	0.99
4	7	3.2e-06	0.00023	21.3	4.0	1	23	400	422	400	422	0.98
5	7	0.00017	0.012	15.8	3.0	1	23	428	450	428	450	0.97
6	7	4.1e-06	0.0003	20.9	0.8	1	23	456	478	456	478	0.96
7	7	7.6e-05	0.0055	16.9	2.3	1	23	484	507	484	507	0.98

Sequence Information

Coding Sequence: ATGGAGTGCAAAGGCAAGGGCAAGAGAATGAAGGAGGAGGCGCCAAGCAAGAAGTTGCCGCCTAAAATTTACGGCGATGGAGGAACCCCCACGAAGGCAGCCCACGACGAGATTCTCTCCTCTTTGCTGCGGATCAACAACTTTGACTCCATATCGAGCATCAAGGATGAGTCGCTGGACATTGATCTGTCCGCCTGTGTGACAATTAGCTCCGCCAGTCTGGTCAACGGAAATAGTCTGTCGTCAACGGATTTTTGGCGGGTGCTGGACGAAAGTGCGCAGAACAACACTGAGCTGAATCTATCGGCGGATGTTTGCCGCGATGACTTGGCGGGCTCCAGCTCCGGCTCTGGCTCCGGCCTTGGGACCACCACCCTTCTACCCGCCAGTACCAGTGAACACCACTCTAGCTCAGAGTTTAACGTGACGTTTCTGCGTCCCGAACCACCGAATGCATTCACCAATTCCCCGTTCAAGAAAACCTCCAGCGGAGTACCCTCATCCATCAAGCTTTCTCCAGAGCAGCTCCAGCTCCAGCAGCAGCAACACCAACTAGTTCAGCCGACCTTACAGCGCAAACCCAAGTTGCCAGCGACGACGGCGTTGCGCTTGAAAGTCTTCAAAGAAGAGCCCCCCGAAGAAAAGCAGCTTCAAATGGGTCAAAGTTCCGCGCATGTGGTCACCAAGGTGGAGGTCAGCGAGGCCGAGTTCTTGCCCCCCTCCTTCACCATCTTTCAGCAGCCCAAGCCGACGTCGAAAACTTCGGCAGAGACGGATGCAGCTAGTATGCCGCCTCCTGTGATTGAGGCTCACGAAAAGTCTGTTGAGGTAGACCCGGCGCCGTTGCACAAGTGCTTGGACTGCAACGGAGTGCTACTGGAGACGCCCGAGGAGTTGGCTAAGCACGAATCGGCCGCCCATCGGCTGCGACTCATCTACCGCTGCGGTGAGTGCCAGCGGGAGTTTGAGGTTTTAGCCGGGCTAAAGAAGCACCTTAAGACTCACCGCACCGAGGGCCGCAAGGATACGTGGAAGAAATGTCCGGACTGCGGCAAGTGCCTCAAATTGGGAAGCATGTGGATGCATCGGAAAATCCATAGCGACAACAAGAAGTACCAGTGTGACATCTGCGGCCAGAAGTTCGTCCAAAAGATCAATCTTACGCACCACGCCCGGATCCACTCCTCTGAGAAGCCGTACGAATGCCCGGAGTGTCAGAAACGATTCCAGGAGCGATCCCATCTGCAGCGCCACCAAAAGTACCATGCCCAGACGCGTTCCTACCGCTGTGAGAAATGCGGAAAAATGTACAAAACAGAGCGCTGCCTTAAGGTGCACAACTTGGTGCATCTGGAGCAGCGTCCGTTTGCCTGCACGGTGTGTGATAAGAGCTTCATCAGCAACTCCAAGCTGAAACAGCATTCGAACATCCACACAGGCATGCGACCGTTCAAGTGCAACTACTGTCCGCGAGACTTTACAAATTTCCCCAACTGGCTGAAGCACACAAGACGCCGCCACAAGGTCGACCATAAGACGGGCGAACACCTTGAAAACATTCCCTCTTACTGCTCCAAGAAGTCCACCACCAGCAAGGCTCAGAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCGATAATCCAGTCCCTACGCATGATTTGAAAACCAAGTCCAATCCACCACCTGCATCCACGCCCGCCCCTGCAAAACAGGCACGTAAAAAGAAGCAGCCTCAGCAGGCTACTCTGGCCGCCTTGGGAATCACTCTGCCAGCGGGAACAGCCCTACAGCAGGTGCATCCTGTGCCGACAGCATCACAGCAACAGGAACTGTCTACTGTGATGGTGACACTTCCCCCACCGCCGCCCAAGCAGGCCAAAGCTAAGCGGGAGCGAAAGCAACTAGCCCCGAAGCAGCTGCAGCAAAAGCCACAGCTGCAGACTCCAAATCAGCAGCCACCGTCCGGATTGGCTCCCTTGAGCAGCATTTCGCAGATCAAGAAAGAGCCGGTGCAGAATCCGGGCCCATTCCTAGACCTACACGGCCTCAGTTTGACTTCTGCGGAGGATCTGATTATGGAGCAGGCACTGGAAATGGAAGAGTGTGGCCTTTATGATGCCCCCGTTGCTAACACCGATATGGGGACATCGGACAATGCCATCTCCGACTCTGCCGCTGCCCTGCACTTCCAGATAAAAAGCGAATTGCCCGACGAGCTCTTGCCAGATGAAGATTTCATGCCTTGCAAACCAAGCGATCGTCTAGCTTGTCCATCACTTGAGTCCTCGCCGTTTTCTTCGCCAGCCTCTATGGAACTGACTGCAGTATCCGCCTCCGCTCCCAGTGGTGCACCAAGCGGATCGCAAGCGATGCCGTCACGTTCTGGGAACTACTATCTGCCCGCCTTTACGCTGAACGCCCAAGGAAAACTAAGCAGCATGGTTAATACAGTGCAATCAGTGGCCGCAGGAGTGCCAACAAGCCCTGCAATGCCCGTAGTAAATGTGCCACTGCTGGTACGCTCCAACCAGATGCTACCGTCAGTGGACACACTGCTGTTTACCACACAAACAGGCGCCAATCGATTCTTTGCGGGAAAATCGGCCACAGCAGCTACGCCGCATCTGACATGA
Protein Sequence: MECKGKGKRMKEEAPSKKLPPKIYGDGGTPTKAAHDEILSSLLRINNFDSISSIKDESLDIDLSACVTISSASLVNGNSLSSTDFWRVLDESAQNNTELNLSADVCRDDLAGSSSGSGSGLGTTTLLPASTSEHHSSSEFNVTFLRPEPPNAFTNSPFKKTSSGVPSSIKLSPEQLQLQQQQHQLVQPTLQRKPKLPATTALRLKVFKEEPPEEKQLQMGQSSAHVVTKVEVSEAEFLPPSFTIFQQPKPTSKTSAETDAASMPPPVIEAHEKSVEVDPAPLHKCLDCNGVLLETPEELAKHESAAHRLRLIYRCGECQREFEVLAGLKKHLKTHRTEGRKDTWKKCPDCGKCLKLGSMWMHRKIHSDNKKYQCDICGQKFVQKINLTHHARIHSSEKPYECPECQKRFQERSHLQRHQKYHAQTRSYRCEKCGKMYKTERCLKVHNLVHLEQRPFACTVCDKSFISNSKLKQHSNIHTGMRPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLENIPSYCSKKSTTSKAQKXXXXXXXXXXXXXXXDNPVPTHDLKTKSNPPPASTPAPAKQARKKKQPQQATLAALGITLPAGTALQQVHPVPTASQQQELSTVMVTLPPPPPKQAKAKRERKQLAPKQLQQKPQLQTPNQQPPSGLAPLSSISQIKKEPVQNPGPFLDLHGLSLTSAEDLIMEQALEMEECGLYDAPVANTDMGTSDNAISDSAAALHFQIKSELPDELLPDEDFMPCKPSDRLACPSLESSPFSSPASMELTAVSASAPSGAPSGSQAMPSRSGNYYLPAFTLNAQGKLSSMVNTVQSVAAGVPTSPAMPVVNVPLLVRSNQMLPSVDTLLFTTQTGANRFFAGKSATAATPHLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615106;
90% Identity: iTF_00504192;
80% Identity: -