Basic Information

Insect: Drosophila malerkotliana
Gene Symbol: -
Assembly: GCA_018153235.1
Location: JAECXV010000198.1:701365-703766[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0029 0.21 12.0 0.8 1 23 170 192 170 192 0.98

2 7 0.0086 0.63 10.5 4.5 1 23 526 548 526 548 0.96

3 7 5.8e-06 0.00043 20.4 2.6 1 23 554 576 554 576 0.98

4 7 7.4e-06 0.00054 20.1 1.0 1 23 582 605 582 605 0.97

5 7 2e-06 0.00015 21.9 2.9 1 23 611 633 611 633 0.97

6 7 3.1e-06 0.00023 21.3 0.6 1 23 639 661 639 661 0.97

7 7 3.8e-07 2.7e-05 24.2 0.6 1 23 667 689 667 689 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0029	0.21	12.0	0.8	1	23	170	192	170	192	0.98
2	7	0.0086	0.63	10.5	4.5	1	23	526	548	526	548	0.96
3	7	5.8e-06	0.00043	20.4	2.6	1	23	554	576	554	576	0.98
4	7	7.4e-06	0.00054	20.1	1.0	1	23	582	605	582	605	0.97
5	7	2e-06	0.00015	21.9	2.9	1	23	611	633	611	633	0.97
6	7	3.1e-06	0.00023	21.3	0.6	1	23	639	661	639	661	0.97
7	7	3.8e-07	2.7e-05	24.2	0.6	1	23	667	689	667	689	0.98

Sequence Information

Coding Sequence: ATGGAGCGCAAGGAAGTGGACACCCAGCAGTTCATAGATCATACGCTGCTGGCCTCGGAACTGCTCCGCGGCGGGGACACCCATCCCTTCATAATGGACTTCATAGACCACTCGGGAGTGTTTCCGAAGGCCGAGGGACCCACGAACCTGAGCACGAATCCTGGCAACCCCACCAACAGCACCAGCGACTCTCTCACTCCCGAGCTGAACTTTCACAGCAGCATCTTCCAGTTCGTGAACAAATCCTCGCCGGAAACGGACGTGGTGGTGCCGCAGCAGGTGGCCCAGCCGGCCTTCCCGGCGCTGGCCATCGAGCCCACGGTTCCCATCGATGTGTCCGCCGGCCTGCACGAGGACGAGGAGCTGTTGTATGCCCCCAACGCCTCAACGACGAATGCGCGCAAGGTGCTGCCCCACAAGAAGCGGATCTCCAGGAAGCTCAAGGGGACCATCGAGGCTGACATGGAGCAGCACAAGAACGTTCAGGATGTGGCGCCTTCTGCCGTCTACAGTTGCGAGATCTGTGGCTACGCCGTGCACACCCAGCTGGACTTTTTCGCCCACCTCAAGCAGCACTACGAGCCCAGCGCCGTCCTGCAGGAGCGCTTGGTGGTCCAGCAGGCCCATCCACTCCCCCTCCCACACCAGCACCAACACCAACAGCAACCGCAGCAGCAAAAGGAGCCCCTTGACATGTGCGGGCTGTCTGCTCAGGACAAGCTGCAACAGGAGCAGGCCAAACTGGACCAGGTCTTCCAGGACGTCCAACTCAACTTTGAGAACTTTCAGAACATCGCCCACCACGTGGACGAAGTGACCAGTGGCGGCGTGAACATGGTCATGCATGGGCAGCCCAACAATGGAGAACAGTGTCCCATGGTGGTCGTCAATCCCGGCTCGAACCCCAGCACCGTTCCCGTGGTGGACGACGTGGAGTTCAGCGACACGGAGGACATGCTGGAAGGCATACGCAACGTGGTCGATAAGGTCTCCATAGAAGACACCTGCGACGAGCTGGTGGACCTCGAACTGACCTCCAGTGCCATGAGGGCGCCGTGGTTCAACAACAACTTCAGCGACATGACCTTCCCGGCTCTGTTGCTGCCCGGAGAACCGCCTCCGACTTCCGCAGAGCAGTCTGCCCCTCTGCTGAAAGACTCGGCCCATCATTCTGAGGACCACATGGCCCTGGACTTCCTGAGCCCCGAAAAGGACGACTCCCAGGGGGGCTCCAAGCTGGAAGAGTCTCTGCCAAAGCCTGGTGAGCCGAATGAGGCCCCCTTGATGGTTGCTGGTGCGCCGCCTCCAGTGTGCCAAACCCCTCCCCCGCCTTCGATCGTTGTTGCGCCCAATTCCACAATCGAGCAGCTGCGGAGATCTCCTCTGGGGCTGGGCGAAGCCTACAAGCTGGACAAAGAGGAACAGGAGGAGGAGGATGTGGGTGACAGCGGTCGGCCGTCTCCGTTCGAGGAGGACGAAGCAGAGGACCCTGAAGACGAGTGCGACGGCGGCTACCATTTAGAGACGCTGGACACGAGTTTGCCGGAGGAGGCTGGGAGCAAGTCGCGTCGGAAGCACTTCTGCGACAAGTGCCAGCGGGACTTCAACTCGTACAACGCCCTGAAGTACCACCAGTACACGCACAACCAGCAGAGATCCCACAAGTGCGACAGCTGCGAGAGGTCCTTCTACACCCAGAGCGCCCTGAAGGCCCACGAGAGGACCCACTCCGACGTGAAGCCGTTCAAGTGCGAAAAGTGCGAGTTCAGTTTCCGGCAGTGGGGCGACCTCAAGTACCACATCATCTCGCGGCACAGCGACATCAAGGCGCACATGTGCGAGTTCTGCGGCAAGAGCTTCTCCCGGCGCTACTCGCTGGTCCTCCACCGGCGCATCCACACCAGCGAGCGCAACTACGCCTGCCAATACTGCGACAAGACCTTCCGGGCCAGCTCCTACCTGATCAGCCACGTGAAAGTGCACACTGGGGAGCGGCCGTACGAGTGCTCCGTCTGCGGCAAGAAGTTCCGAGTGTCGGGGGATCTGAAGCGACATTCCCGGATCCACGATCCCGCCAGAGCCAGCAACCCCTCCCCCACAGCGGCGAAAGTCAAGAAGAAAAAGTCCGCCGGCCAAGCGGAACTGAGGCCGGCGGAGGAGTTGGAAGCCAGCCCAGGCACCCTTAATCACAAGTCTGACGCCATGTGCGAGTCCGAGCAGGGCGTTCTGCGCTTATAG
Protein Sequence: MERKEVDTQQFIDHTLLASELLRGGDTHPFIMDFIDHSGVFPKAEGPTNLSTNPGNPTNSTSDSLTPELNFHSSIFQFVNKSSPETDVVVPQQVAQPAFPALAIEPTVPIDVSAGLHEDEELLYAPNASTTNARKVLPHKKRISRKLKGTIEADMEQHKNVQDVAPSAVYSCEICGYAVHTQLDFFAHLKQHYEPSAVLQERLVVQQAHPLPLPHQHQHQQQPQQQKEPLDMCGLSAQDKLQQEQAKLDQVFQDVQLNFENFQNIAHHVDEVTSGGVNMVMHGQPNNGEQCPMVVVNPGSNPSTVPVVDDVEFSDTEDMLEGIRNVVDKVSIEDTCDELVDLELTSSAMRAPWFNNNFSDMTFPALLLPGEPPPTSAEQSAPLLKDSAHHSEDHMALDFLSPEKDDSQGGSKLEESLPKPGEPNEAPLMVAGAPPPVCQTPPPPSIVVAPNSTIEQLRRSPLGLGEAYKLDKEEQEEEDVGDSGRPSPFEEDEAEDPEDECDGGYHLETLDTSLPEEAGSKSRRKHFCDKCQRDFNSYNALKYHQYTHNQQRSHKCDSCERSFYTQSALKAHERTHSDVKPFKCEKCEFSFRQWGDLKYHIISRHSDIKAHMCEFCGKSFSRRYSLVLHRRIHTSERNYACQYCDKTFRASSYLISHVKVHTGERPYECSVCGKKFRVSGDLKRHSRIHDPARASNPSPTAAKVKKKKSAGQAELRPAEELEASPGTLNHKSDAMCESEQGVLRL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615069;
90% Identity: iTF_00550413;
80% Identity: -