Basic Information

Insect: Drosophila malerkotliana
Gene Symbol: -
Assembly: GCA_018153235.1
Location: JAECXV010000067.1:23114200-23117771[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 4.5e-05 0.0033 17.6 1.6 1 23 244 266 244 266 0.93

2 9 1.1e-08 8.2e-07 29.0 2.6 1 23 272 294 272 294 0.98

3 9 4.6e-06 0.00034 20.7 0.8 1 23 300 322 300 322 0.98

4 9 3.3e-06 0.00024 21.2 1.0 1 23 328 350 328 350 0.97

5 9 1.6e-05 0.0012 19.0 1.4 2 23 440 461 439 461 0.96

6 9 1.7e-09 1.3e-07 31.5 1.6 1 23 467 489 467 489 0.98

7 9 0.0021 0.15 12.4 0.9 3 23 497 517 495 517 0.97

8 9 5.7e-05 0.0042 17.3 0.9 1 23 523 545 523 545 0.99

9 9 8.9 6.5e+02 1.0 0.9 1 12 551 564 551 567 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	4.5e-05	0.0033	17.6	1.6	1	23	244	266	244	266	0.93
2	9	1.1e-08	8.2e-07	29.0	2.6	1	23	272	294	272	294	0.98
3	9	4.6e-06	0.00034	20.7	0.8	1	23	300	322	300	322	0.98
4	9	3.3e-06	0.00024	21.2	1.0	1	23	328	350	328	350	0.97
5	9	1.6e-05	0.0012	19.0	1.4	2	23	440	461	439	461	0.96
6	9	1.7e-09	1.3e-07	31.5	1.6	1	23	467	489	467	489	0.98
7	9	0.0021	0.15	12.4	0.9	3	23	497	517	495	517	0.97
8	9	5.7e-05	0.0042	17.3	0.9	1	23	523	545	523	545	0.99
9	9	8.9	6.5e+02	1.0	0.9	1	12	551	564	551	567	0.87

Sequence Information

Coding Sequence: ATGGCCATCAACTTTTCGGCCTCTTTCGCGGCCTGCATAGCAGCCGGGTTAAAAGTGCCGCGACAAATCATGTACTGCATTACGCAGGACACGGGGCAGCCTGGCGATGGTCGCCAGCAACAAGTGTCGCCTTCCTCCAGCCCCTACCCGTCGGTGCAGCAACGAGGAAATGGTGGGGGAGAAGAAGACGCAATGAACCAGCTGGCTAATCAACAGAACTCTGCGCCCAACCAAAACCAAAGCAGCAACGATCCCCAGCACGCCGCACCCAACGCTGGGGAGACCGGAAACCCACACGTGCAGCAGAACGGGGGTGGCCCTCAAGGGGATCCTGGAAACGGATTTCAAACTGCGCCGGACTACTACGCCTCTCGCCATGCGCCTCCCCAAGGGGGAATGCTAGCCCCTCCCGGATTTCCGCCTCTCCACTATCTTAACAAAGGCGTCTTGCCCATGGAGCAGGCCGGCGGTGGCGGCGGGGGAAGCGGAGGCGGAAGCGAATCCTACTCCATGCCCGAGCTACTGCCTAGTCAACAAAACGGCCAGCAAAGCGCCGGGCCGGCAAATGCAAATGCCAATGAAGGCGCTGCAGCGGCCAACGGAGGAGGAGTAGGTGCGACCGGTGCGGGAGCCGGCGTTGGCACGGTCAGTGGCGTGGCGACTGGAGGACGGACGGGTAATGGTCCCGGGCGTCCGCATAAAAACAAGCCACATAGTGATTTACGGTTGTTCAAGTGCCTCACATGCGGCAAGGACTTTAAGCAGAAAAGCACTCTGCTGCAACACGACCGCATCCATACAGACGCACGTCCCTTTCCGTGCTCCGAATGCGGAAAACGCTTCCGCCAGCAGTCGCACCTCACGCAACACCTGAGAATCCACGCCAACGAAAAGCCCTTCACCTGCCCGTACTGTTCGCGCAGCTTCCGGCAGCGTGCCATTCTTAACCAGCACATACGCATCCATTCGGGTGAGAAGCCCTTCGCCTGCCCCGAGTGCGGCAAGCACTTTCGCCAGAAGGCCATCCTCAATCAGCATGTGCGCACCCACCAAGATGTCTCACCCCATCTCATATTCAAGAACGGGCCGCACCCCACACTGTGGCCTTCGGACGTTCCTTTTCCGGGCGAGGAGAACGACACCAAGGGGGACATCGCAGGAGGCAGCGGGTATCACGACGAGGATTCGCAGGGTACACCCGATGGCAGTGGCGGCATGCATTATCCCTCATATTTCAAGGACGGCAAAGGACAAAAGATATTGCCCGAGGTCCTTCAGCATATTGGAGTACGGCCTGCCAACATGCCGCTTTACGTTCGCTGCCCCATCTGTGACAAAGAGTTTAAGCAAAAGACGACCCTTTTGCAACATGGTTGCATCCACATAGAATCGCGGCCATATCCTTGCCCGGAGTGCGGAAAGCGGTTCCGACAACAATCGCATCTTACGCAGCACCTTCGCATTCACACCAATGAAAAACCATTTGGCTGCATGTACTGCCCGCGCTTCTTCCGCCAGCGAACTATTCTTAACCAGCACTTGCGCATCCATACCGGTGAAAAGCCATACAAGTGTGGCCAGTGCGGCAAGGACTTCCGTCAAAAGGCCATACTTGACCAACACACACGCACCCACCAGGGAGACCGACCATTCTGCTGCCCGATGCCTAACTGCCGGCGGCGTTTTGCCACCGAGAACGAGACGGTCACGCTGTCTATCACGCTACCGCCTCCGCCGAGTACCCATTCGGATCATGCGGGCCATCCAGGAATGGCAAATGGAGCTCCATCCCAACCACCTACAACTTTATCACATGCAATTCCCATACATCCACATATACACTCGATATTTGGTTCTCTATAA
Protein Sequence: MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPGDGRQQQVSPSSSPYPSVQQRGNGGGEEDAMNQLANQQNSAPNQNQSSNDPQHAAPNAGETGNPHVQQNGGGPQGDPGNGFQTAPDYYASRHAPPQGGMLAPPGFPPLHYLNKGVLPMEQAGGGGGGSGGGSESYSMPELLPSQQNGQQSAGPANANANEGAAAANGGGVGATGAGAGVGTVSGVATGGRTGNGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEENDTKGDIAGGSGYHDEDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATENETVTLSITLPPPPSTHSDHAGHPGMANGAPSQPPTTLSHAIPIHPHIHSIFGSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00566232; iTF_00476069;
90% Identity: iTF_00566232;
80% Identity: -