Basic Information

Insect: Drosophila malerkotliana
Gene Symbol: -
Assembly: GCA_018153235.1
Location: JAECXV010000058.1:1164046-1166046[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.4e-06 0.0001 22.4 2.3 1 23 160 182 160 182 0.98

2 15 8.3e-05 0.0061 16.8 4.3 1 23 191 214 191 214 0.98

3 15 1.3e-06 9.5e-05 22.5 1.7 1 23 231 253 231 253 0.98

4 15 0.00039 0.029 14.7 4.0 1 23 259 282 259 282 0.98

5 15 7.4e-05 0.0054 16.9 2.4 1 23 293 315 293 315 0.98

6 15 0.0014 0.11 12.9 4.1 1 23 357 379 357 379 0.99

7 15 0.17 13 6.4 1.0 1 20 385 404 385 406 0.95

8 15 0.00018 0.013 15.8 2.3 1 23 418 440 418 440 0.99

9 15 5.2e-05 0.0038 17.4 3.7 1 23 446 468 446 468 0.97

10 15 6.6e-05 0.0048 17.1 1.6 1 23 482 504 482 504 0.97

11 15 6.1e-07 4.5e-05 23.5 0.4 1 23 510 532 510 532 0.94

12 15 7.4e-06 0.00054 20.1 1.5 1 23 538 561 538 561 0.95

13 15 8e-05 0.0058 16.9 0.7 1 23 567 589 567 589 0.98

14 15 0.00091 0.067 13.5 0.9 1 23 594 616 594 616 0.98

15 15 2.7e-06 0.0002 21.5 1.0 1 23 626 648 626 648 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.4e-06	0.0001	22.4	2.3	1	23	160	182	160	182	0.98
2	15	8.3e-05	0.0061	16.8	4.3	1	23	191	214	191	214	0.98
3	15	1.3e-06	9.5e-05	22.5	1.7	1	23	231	253	231	253	0.98
4	15	0.00039	0.029	14.7	4.0	1	23	259	282	259	282	0.98
5	15	7.4e-05	0.0054	16.9	2.4	1	23	293	315	293	315	0.98
6	15	0.0014	0.11	12.9	4.1	1	23	357	379	357	379	0.99
7	15	0.17	13	6.4	1.0	1	20	385	404	385	406	0.95
8	15	0.00018	0.013	15.8	2.3	1	23	418	440	418	440	0.99
9	15	5.2e-05	0.0038	17.4	3.7	1	23	446	468	446	468	0.97
10	15	6.6e-05	0.0048	17.1	1.6	1	23	482	504	482	504	0.97
11	15	6.1e-07	4.5e-05	23.5	0.4	1	23	510	532	510	532	0.94
12	15	7.4e-06	0.00054	20.1	1.5	1	23	538	561	538	561	0.95
13	15	8e-05	0.0058	16.9	0.7	1	23	567	589	567	589	0.98
14	15	0.00091	0.067	13.5	0.9	1	23	594	616	594	616	0.98
15	15	2.7e-06	0.0002	21.5	1.0	1	23	626	648	626	648	0.98

Sequence Information

Coding Sequence: ATGGCGCATCCTGCAGTCTTGAGGCGCCACGTACCTATAAAGAGTGAGGCGACCGAAGAGGAGTACGTTCTTCAGGAAGCGTTTATACGAATTTCGGGCAAAAACGATGTGCTGCTCAATAAACTCAGGAGAAGTGAAGAGGAAGGCCCCGGATTCGGAAACAAAAACACATTCCTGGTGAAAAACGAGCCCATTGATGAAGAGCTTCTGTCGTATGGCATTTTGGAGCAGCCCCCTAGTCCAAGTGAGAGCATCCACTTTGATACCATTATTAAGGAAGAGGTCCCACAGCTTCCCATTGACGTCAACGAAAACTGCGTCGATGTGGAGTTTGAGAGTGAGGAAAGTTTGCTCGAAAGATTAAGCAATAGAGATAGTAGCTGCCACGATGGCGAAGTGGACTTTGACGATGAGGATGACGACTACGTGGAGTCTCAAGATAGTTCTGAGTACTCCGAAAACGAAGGCTCGGGTTCATTCAAGTGCTCCCGTTGTCCCAAGAGCTTTACATTTGCAAAAAACCTCAAGAAACACCTAAACGCTCACCCGTCTGACACGGGAAAGCGCACCTACAAGTGTAAACACTGCCAAAAGGTCTATACGCAAAGAGCACGCTACAAAAATCACCTTATCACCGACCACAATGATGAGGATTCGGAACTAGATGATAACTCCGATGAGGAAAAGATTTACAATTGCGCTCGTTGCCCCAAGACGTTCAAATATTTGTCAAACCTGCGAAAACACGCCCGGATGCACACTGCCGGGCTTCCCTACAAGTGCAACCGCTGTCATATGACCTTCTCCCAAAAAGCACGTTACGAGACACATAAGCGTGTTCCCCACAAAGCGGATGGAACACCTATGGATCGCCCATTCAAGTGCTCAAAGTGTGAAAAAAGGTTTAAAAAAGAAATCCAAATGATTCGTCACGCTCGGAGCCATAAATCCAGGAAAATGGCCAGGGGTAAGAAATCCTCAAAGGAGGATGAGAGTACAGATTCAGAGGTATCGGAAGAAGATGCCGAATGTTTTTCGAAAGAACTCCATGACGACGGCACATATACGTACAAGTGCCGATTTTGCAACCAAAGTATTAAATACAAGTGGAATTTTAAGAGGCACCTTCTTCGCCACGCTGACAGTCGTCCTTATAAGTGCGACCGATGCGCCGCAACCTTTTTCACTGAAAAACGCTACAAGAAGCACTTGTTGCTGATCAAACCTGATGGAAAGTGCCCGTCTGCTTCTTTTCAGTGCACTCAGTGCCTGGCGACTTTTGAATCGCAAAAATTTCTAACTCGTCACGTCCGGAGACATGACCCAAACTGGTGGCACGAATGTCTCATATGCCAGAAAACGTTTCAGAGCGCCAGTGGCCTCAGGAAACATCACAAAGTCCATATTTTTCCTAGAGAGCCCCCGAAACAACAGGCGCTTTCACACCACTGCAGCGTTTGTTCGAAATCTTTCGCGGCAGCTGGGTACCTGTTTATACACATGCGGGTGCATACGGGCGAAAGGCCATTCCAATGTACTGAATGTGGAAAAAGTTACAAACAGAAGGGGCAACTCGCTGTGCATATGCCTACCCATACCGGAGAGCGGAAGTACAATTGTGAACAGTGTACCATGTCGTTCACATACAAATCTTCACTCAAGCGGCATGTAATGAACGTACATAGTAACGGGCGGCCATTCGAATGTCCGGATTGCGATGAAACCTTTGCTTCAATGTATAGGATGCGGGAGCACAAGAAAACCCATTCCACTGAGCGCTACAAGTGCTCCGAATGCCCAATGACTTTCGTATCGGAACACGGCCAGAAAGTGCATAGGCTGATTCACCTAAAGCCACCTGTTGCAGCTAAACGATTCCAATGCCCCCATTGCCCCAAGAACTTTGCCAGAAATCAAGGGTTGAAGATGCACAGGATAGTCCACGAGATGCCCAGCTCTGCCAAAAAAAAACCGGAAATAGAATACGCAACCGAATCCTGA
Protein Sequence: MAHPAVLRRHVPIKSEATEEEYVLQEAFIRISGKNDVLLNKLRRSEEEGPGFGNKNTFLVKNEPIDEELLSYGILEQPPSPSESIHFDTIIKEEVPQLPIDVNENCVDVEFESEESLLERLSNRDSSCHDGEVDFDDEDDDYVESQDSSEYSENEGSGSFKCSRCPKSFTFAKNLKKHLNAHPSDTGKRTYKCKHCQKVYTQRARYKNHLITDHNDEDSELDDNSDEEKIYNCARCPKTFKYLSNLRKHARMHTAGLPYKCNRCHMTFSQKARYETHKRVPHKADGTPMDRPFKCSKCEKRFKKEIQMIRHARSHKSRKMARGKKSSKEDESTDSEVSEEDAECFSKELHDDGTYTYKCRFCNQSIKYKWNFKRHLLRHADSRPYKCDRCAATFFTEKRYKKHLLLIKPDGKCPSASFQCTQCLATFESQKFLTRHVRRHDPNWWHECLICQKTFQSASGLRKHHKVHIFPREPPKQQALSHHCSVCSKSFAAAGYLFIHMRVHTGERPFQCTECGKSYKQKGQLAVHMPTHTGERKYNCEQCTMSFTYKSSLKRHVMNVHSNGRPFECPDCDETFASMYRMREHKKTHSTERYKCSECPMTFVSEHGQKVHRLIHLKPPVAAKRFQCPHCPKNFARNQGLKMHRIVHEMPSSAKKKPEIEYATES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -