Basic Information

Insect: Drosophila maculinotata
Gene Symbol: -
Assembly: GCA_035045305.1
Location: JAWNPD010000335.1:23008289-23012432[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00021 0.014 15.9 0.7 1 23 143 166 143 166 0.96

2 14 0.0019 0.13 12.9 3.1 2 23 215 237 211 237 0.90

3 14 0.0079 0.54 10.9 0.8 1 23 340 363 340 363 0.93

4 14 1.2 79 4.1 4.7 2 23 412 434 411 435 0.95

5 14 0.0035 0.24 12.0 0.5 1 23 498 521 498 521 0.88

6 14 2.1 1.4e+02 3.3 0.1 2 14 540 552 539 564 0.85

7 14 0.00074 0.05 14.1 3.3 2 23 572 594 572 594 0.96

8 14 8.3e-05 0.0056 17.1 0.2 1 23 686 709 686 709 0.95

9 14 0.00012 0.0079 16.7 0.3 1 23 762 785 762 785 0.93

10 14 0.0012 0.084 13.4 2.2 2 23 835 857 834 857 0.97

11 14 0.002 0.13 12.8 2.0 1 23 943 966 943 966 0.92

12 14 0.051 3.5 8.3 2.3 1 21 1018 1038 1018 1039 0.95

13 14 0.082 5.6 7.7 0.5 3 23 1081 1104 1080 1104 0.95

14 14 9.3 6.3e+02 1.2 1.4 1 12 1122 1135 1122 1146 0.64

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00021	0.014	15.9	0.7	1	23	143	166	143	166	0.96
2	14	0.0019	0.13	12.9	3.1	2	23	215	237	211	237	0.90
3	14	0.0079	0.54	10.9	0.8	1	23	340	363	340	363	0.93
4	14	1.2	79	4.1	4.7	2	23	412	434	411	435	0.95
5	14	0.0035	0.24	12.0	0.5	1	23	498	521	498	521	0.88
6	14	2.1	1.4e+02	3.3	0.1	2	14	540	552	539	564	0.85
7	14	0.00074	0.05	14.1	3.3	2	23	572	594	572	594	0.96
8	14	8.3e-05	0.0056	17.1	0.2	1	23	686	709	686	709	0.95
9	14	0.00012	0.0079	16.7	0.3	1	23	762	785	762	785	0.93
10	14	0.0012	0.084	13.4	2.2	2	23	835	857	834	857	0.97
11	14	0.002	0.13	12.8	2.0	1	23	943	966	943	966	0.92
12	14	0.051	3.5	8.3	2.3	1	21	1018	1038	1018	1039	0.95
13	14	0.082	5.6	7.7	0.5	3	23	1081	1104	1080	1104	0.95
14	14	9.3	6.3e+02	1.2	1.4	1	12	1122	1135	1122	1146	0.64

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTATGGACGTCTATGTTTTCGGCCGACTTTGAGGAAGGCGATGCAGTGGCGGCCGGGAGCTATAATCATGCCGTGGGAGGGCTGATGGGCGATGGGGAGGAGGAGGAcgcagatgatgatgatgatggtggaGGGGGAGGGAAAAAAGGACCCGAGCCGGATGATGATGCCATATTTGATTTTGAACTGGAGCCAATTGTCAGCATTGCGGAACCGCCACGAACCCCAGCTGCCCGCTTGGCGCCAACAATCCCAGTTGCTCAGCCCGTGCGtccgcatcatcatcatatcCAGTCCTCGATGGGAATACGAGGAGGAGGTGCCGCTGCACCACCCACTCGACCGACAACATCACAAATCAATGCAACGGACGAGAATGGTGTGCCCATCAATTATGAACTGGGCGTCATTTATATATGTCCCGCCTGCGGCACAGAGTATCGTCACCAGGACATGTGGAAGAGACACATGAACCAGATGCATCAGTTTAATACGCGCCGTGGTCTCAACTTTGTGGGTATAGATAAGCTGTATCATCGCTGCCTGGAGTGCAACAAGCGGATCGCGATGCACAGCCGGGAGAATCTGCTGAAGCACAAGTTCACCCATTTGCCATTCCGTTGCACCAAGTGCTACATTTGTAAGCGCGAGTACAAGTACAGGCAGGACCTGATGGTCCATCTGCGCATGGTCCACTGTGATGAGGTGGTTGCGATGATGCGCGCCGGGGATGGTAGTGCTGGCAGGAAGACGCGCGTCCGTGAACCGCGCATTGAGCAGCAACGCGGTCCGGTTCATAACCTCTATAAGCCGGCGCGTGACGATGATGACGGCATAGAGGTCAAGAATGAGCTGTTGGACGCGGAGGGAACGGCTACCGATGAGTTGGATGACGATTCTAATCATATCTCCAACCAGGCCAAGAAGAAACGTACCAATACGCCTGCAGGCtctggcaatggcaatgccgGCGCTTCGGACATCTGCGAGGACTATATACACTACATGTGTCCTGATTGTGGGACAGAATGCGAAACTCATGCCCAGTGGAGTCAGCACATTGAGTTCGTGCACGACTATGTCAGCCGGCGTGGGCTCAACTTTCGCTGCGTGGACATGCAGATGCAGTGCCTCGAGTGCAAGCAGTTTGTCGTCCCGAACACAATCAAAACGCTGCGCGCACACAAGTTCAGCCATTTAGCGCAGCCGGAGTGGATACGTTGCAAGTTGTGTTACCAAGGCTACACGGAGCATCATGAGCTGGTTACGCATCTGCTCAAGCAGCATCATTTGGACACCCTAGTGCCCGACGAGGAGGAGCCAAAGCCAAGTTCCAGTGCCGGAGCCGGCGATGATGCTGAGGAGAACTCAGTCGTTGGCAATGGCTGCGATGATGAATCcttgttgcaatttgatgATGTGCCACGTAGAGGTGGGCGCATTGGTAGCGATGATATGTATGAGCCGCATATTGATTATCTGTGCCCGCAGTGCGGCAGAGAGTTCATTGAGAAGAAGCACTGGCGCACACATGTCGTTCAGGTGCACGGTATGAATGATCTGGCTAAGCTGAACTTTGAGGTCATCAACGATCGTCAGCTCAAGTGCACCGAATGCGACAAGATCATCACGAATGCCTATGGCATACAAAATGCCCAGCAGCATAGGATTACACATCTGCCCTTTAAAGCATATGCTCGTTGTCGCAAATGCCACAAGTCCTATACAGATCGCAAGGGTCTCGTCAAGCATTTGGCGACATACCATCGCGTGGGCTATGAGCCGCGCAAATCTGGAGCTAGTGGAGCGGTTGCCGGTGGATGTCCTGGCCAGGTCAAGCCACAGACACCGCGCAAGCAAATTGTAACCGTAGCTAATGAAACTTATGAGATTATCTATTTAGATGAGGAGCAATCGCCGCCAAGTAATAATAACATAAATGAGGAGAATGACTTTGGCGAGCAAATGCAAGCGGATGATGAGGATTATGCCATAGGCAGCACTAGTACAGCAGCTGCCCCCAATCCCAATGCGAATCGCTATAAATGCGTAGACTGCGGATCCTTGTTCTCCACCCAGTCGGCGCTCAAGACGCACATTAGCGAGGAGCATGACTTTATGGACACGCAATATGGTGCCAAGAAATTTGACAATGCTGAACCCACAAAGGAgacagcgccagcagcagcagcgggtgCACTCGTGGCGACCACCACATCACCAGCCAAAATCTGCACAAGTGGCTCCACCATCGAACAGAACTATATATTCCTTTGCCCATCGTGCGGCAAGCCCTACAAGACGCAATTCGAGTGGCGTCGCCACATCAACGAGGAGCACAACTTTGATAAGCGGCAATATTTGAATATGCGTCAGCTGGACAAGTATCGCTTTCAGTGCACACAGTGCAAGGACATTGTGTGCAATTCGAAGCTAAAAGGACTGCAGGATCATCATTTCCGACATCTGGCTTATAGACTTTACTTGAAGTGCCTCGTTTGCGGCACCTGCTACAACCATAAGCCCAACATTGCCGCACATTTGCGCACGCGCCACAACATCTACGAACGGGACACGAACTGGCGTGAACTGCAACCGAAGCCGCAAAATGGCTACGACACCATAAATTATAGAGATAAGGATATGCAAGCCATAGTCGGTTCCAGCTCAGGCTCGCCCACgcctggcagcagcagtggagGTCGCTCGCTGAAACCACAGCCTGGTCTGCTACCCACGCGACCCGCTGGCCTGAACACACTGGAGGACAGCATCTCCTATCATAATGCTGTCGATCTGGACTTCATTACCTACTACTGCCCCAAGTGCAACAAAAACTTTGATTCGCACGCCTTCTGGCGGAAACACATTGTCGAGCAGCACAATTTTAACAGCCGGCAGGGTTTAAACTTTCGCCAAATCGACAACCATCACTACCTGTGCCTGGAGTGTTATAAGCGGGTCACAGTCACCCATACCAAGGGTGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGGCACCTGCCTTACCGCTCTTTTAAGTGCTTGACCtgcaatggaaaatttgtgcgcaaacaaatgtttttcaagCACTTGAATCGGGATACCAATCGCTGCGATAGCAAACCTCTAAGCGTGGAGGATAACGACGATGACACCGCAGAGCAGCTGGAGAGAGCGGCGTCCGTTAACGATATCGCTGATACCGTTGCATATCGCCTGCTGTGCCCGCAGTGCGGCGATAAATTCAGCACCACCACAAAATCTCTGTGGCGCAAGCATATTAATATTCAGCATGGTCTAGCCAAGTGTGATGTGCTGCATATGCGTAAGCTGGGCGAGCAGCTCTATCGCTGCACGGACTGCGATGTGCAGATTCCAACGAAACAGCTGTGcgtgctgcagcagcatcgtTTCCAACATTTGCCCTATGCTGCCTATATACGCTGTCAGCTctgcgagcagcagcagccggatgGATTGGGTCATGGCGCTGTGTCAGCCGGAATGCACAGCATGCTGGAGCTAAAGCAGCACATGCGTGCTGAGCATCCCACGTTTGCAGATAACGAGCAAAAAATGGAAGTGCTGCTGGATGACGACGAGGACAGCCAGCCGGCGGACAACAATGAGAAGGCGGAGATCGATGAGTCGGATGACAATGGCCCGTATATGCCACTGCCGCCGCATTTACTGGACGACGACGTAGGTAACATAGGGTTTGAGGATCAATATTTGCTGGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEGDAVAAGSYNHAVGGLMGDGEEEDADDDDDGGGGGKKGPEPDDDAIFDFELEPIVSIAEPPRTPAARLAPTIPVAQPVRPHHHHIQSSMGIRGGGAAAPPTRPTTSQINATDENGVPINYELGVIYICPACGTEYRHQDMWKRHMNQMHQFNTRRGLNFVGIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRAGDGSAGRKTRVREPRIEQQRGPVHNLYKPARDDDDGIEVKNELLDAEGTATDELDDDSNHISNQAKKKRTNTPAGSGNGNAGASDICEDYIHYMCPDCGTECETHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVVPNTIKTLRAHKFSHLAQPEWIRCKLCYQGYTEHHELVTHLLKQHHLDTLVPDEEEPKPSSSAGAGDDAEENSVVGNGCDDESLLQFDDVPRRGGRIGSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKSGASGAVAGGCPGQVKPQTPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDEDYAIGSTSTAAAPNPNANRYKCVDCGSLFSTQSALKTHISEEHDFMDTQYGAKKFDNAEPTKETAPAAAAGALVATTTSPAKICTSGSTIEQNYIFLCPSCGKPYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRFQCTQCKDIVCNSKLKGLQDHHFRHLAYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERDTNWRELQPKPQNGYDTINYRDKDMQAIVGSSSGSPTPGSSSGGRSLKPQPGLLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGKFVRKQMFFKHLNRDTNRCDSKPLSVEDNDDDTAEQLERAASVNDIADTVAYRLLCPQCGDKFSTTTKSLWRKHINIQHGLAKCDVLHMRKLGEQLYRCTDCDVQIPTKQLCVLQQHRFQHLPYAAYIRCQLCEQQQPDGLGHGAVSAGMHSMLELKQHMRAEHPTFADNEQKMEVLLDDDEDSQPADNNEKAEIDESDDNGPYMPLPPHLLDDDVGNIGFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -